NZ288940A - 4-amino-2-oxo-1-piperidineacetic acid tripeptide derivatives as thrombin inhibitors - Google Patents

4-amino-2-oxo-1-piperidineacetic acid tripeptide derivatives as thrombin inhibitors

Info

Publication number
NZ288940A
NZ288940A NZ288940A NZ28894095A NZ288940A NZ 288940 A NZ288940 A NZ 288940A NZ 288940 A NZ288940 A NZ 288940A NZ 28894095 A NZ28894095 A NZ 28894095A NZ 288940 A NZ288940 A NZ 288940A
Authority
NZ
New Zealand
Prior art keywords
oxo
amino
thrombin inhibitors
piperidineacetic acid
tripeptide derivatives
Prior art date
Application number
NZ288940A
Other languages
English (en)
Inventor
Joseph Edward Semple
Robert J Ardecky
Ruth F Nutt
William Charles Ripka
David C Rowley
Marguerita S Lim-Wilby
Terrence K Brunck
Original Assignee
Corvas Int Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corvas Int Inc filed Critical Corvas Int Inc
Priority claimed from PCT/US1995/007661 external-priority patent/WO1995035311A1/en
Publication of NZ288940A publication Critical patent/NZ288940A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NZ288940A 1994-06-17 1995-06-19 4-amino-2-oxo-1-piperidineacetic acid tripeptide derivatives as thrombin inhibitors NZ288940A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US26137894A 1994-06-17 1994-06-17
US35683194A 1994-12-13 1994-12-13
US48700795A 1995-06-07 1995-06-07
PCT/US1995/007661 WO1995035311A1 (en) 1994-06-17 1995-06-19 3-amino-2-oxo-1-piperidineacetic derivatives as enzyme inhibitors

Publications (1)

Publication Number Publication Date
NZ288940A true NZ288940A (en) 1999-01-28

Family

ID=27401400

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ288940A NZ288940A (en) 1994-06-17 1995-06-19 4-amino-2-oxo-1-piperidineacetic acid tripeptide derivatives as thrombin inhibitors

Country Status (8)

Country Link
EP (1) EP0802923A1 (xx)
CN (1) CN1151166A (xx)
AU (1) AU700808B2 (xx)
BR (1) BR9508048A (xx)
CA (1) CA2192210A1 (xx)
MX (1) MX9606566A (xx)
NO (1) NO965353L (xx)
NZ (1) NZ288940A (xx)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4192875A (en) * 1979-02-02 1980-03-11 Merck & Co., Inc. Cyclic hexapeptide

Also Published As

Publication number Publication date
NO965353L (no) 1997-02-17
MX9606566A (es) 1997-07-31
AU700808B2 (en) 1999-01-14
EP0802923A1 (en) 1997-10-29
CA2192210A1 (en) 1995-12-28
NO965353D0 (no) 1996-12-13
BR9508048A (pt) 1997-11-18
AU2863095A (en) 1996-01-15
CN1151166A (zh) 1997-06-04

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