NO963358L - Vertsvektor-system til anvendelse i genterapi - Google Patents
Vertsvektor-system til anvendelse i genterapiInfo
- Publication number
- NO963358L NO963358L NO963358A NO963358A NO963358L NO 963358 L NO963358 L NO 963358L NO 963358 A NO963358 A NO 963358A NO 963358 A NO963358 A NO 963358A NO 963358 L NO963358 L NO 963358L
- Authority
- NO
- Norway
- Prior art keywords
- gene
- env
- contg
- transgene
- sequence
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1276—RNA-directed DNA polymerase (2.7.7.49), i.e. reverse transcriptase or telomerase
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10361—Methods of inactivation or attenuation
- C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13045—Special targeting system for viral vectors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13051—Methods of production or purification of viral material
- C12N2740/13052—Methods of production or purification of viral material relating to complementing cells and packaging systems for producing virus or viral particles
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13061—Methods of inactivation or attenuation
- C12N2740/13062—Methods of inactivation or attenuation by genetic engineering
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2750/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssDNA viruses
- C12N2750/00011—Details
- C12N2750/14011—Parvoviridae
- C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
- C12N2750/14141—Use of virus, viral particle or viral elements as a vector
- C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/60—Vectors comprising as targeting moiety peptide derived from defined protein from viruses
- C12N2810/6045—RNA rev transcr viruses
- C12N2810/6054—Retroviridae
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2810/00—Vectors comprising a targeting moiety
- C12N2810/50—Vectors comprising as targeting moiety peptide derived from defined protein
- C12N2810/80—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates
- C12N2810/85—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian
- C12N2810/855—Vectors comprising as targeting moiety peptide derived from defined protein from vertebrates mammalian from receptors; from cell surface antigens; from cell surface determinants
Abstract
System for ekspressjon av et transgen i en målcelle eller humant eller animalt vev kjennetegnet ved at det består av en linjeetablert eukaryotisk celle, hvori det er transfektert: a) en rekombinant virussekvens hvori et gen har vært slettet enten fullstendig eller delvis og erstattet med transgenet; b) en nukleinsyresekvens hvilken inkluderer en sekens som koder det slettede protein, idet sekvensen styres av en promotor og, om nødvendig, er assosiert med transgenet, og ved sin 3' ende er flankert av et polyadenyleringspunkt. Det rekombinante virusgenom og sekvensen som bæres av en eller to plasmidformede bærere tenderer til å være transkomplimentære og gjøre det mulig for vertcellen å frembringe defekte infektuøse vimser.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9401994A FR2716461A1 (fr) | 1994-02-22 | 1994-02-22 | Système hôte-vecteur utilisable en thérapie génique. |
FR9415135A FR2716459B1 (fr) | 1994-02-22 | 1994-12-15 | Système hôte-vecteur utilisable en thérapie génique. |
PCT/FR1995/000208 WO1995022617A1 (fr) | 1994-02-22 | 1995-02-22 | Systeme hote-vecteur utilisable en therapie genique |
Publications (2)
Publication Number | Publication Date |
---|---|
NO963358D0 NO963358D0 (no) | 1996-08-13 |
NO963358L true NO963358L (no) | 1996-09-02 |
Family
ID=26230967
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO963358A NO963358L (no) | 1994-02-22 | 1996-08-13 | Vertsvektor-system til anvendelse i genterapi |
Country Status (14)
Country | Link |
---|---|
US (2) | US5948675A (no) |
EP (2) | EP0855185A3 (no) |
JP (1) | JP3681752B2 (no) |
AT (1) | ATE172496T1 (no) |
AU (1) | AU1851895A (no) |
CA (1) | CA2183151C (no) |
DE (1) | DE69505493T2 (no) |
DK (1) | DK0738327T3 (no) |
ES (1) | ES2124532T3 (no) |
FI (1) | FI963246A (no) |
FR (1) | FR2716459B1 (no) |
IL (1) | IL112736A0 (no) |
NO (1) | NO963358L (no) |
WO (1) | WO1995022617A1 (no) |
Families Citing this family (46)
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FR2736931B1 (fr) | 1995-07-17 | 1997-09-19 | Univ Paris Curie | Sequences regulatrices issues du gene cd4 et a expression specifique dans les lymphocytes t matures |
PT880594E (pt) * | 1996-01-23 | 2003-03-31 | Oxford Biomedica Ltd | Vector retroviral e sua utilizacao em terapia genica |
FR2747046B1 (fr) * | 1996-04-05 | 1998-06-19 | Univ Paris Curie | Nouveaux vaccins issus de plasmovirus |
US6818209B1 (en) | 1998-05-22 | 2004-11-16 | Oxford Biomedica (Uk) Limited | Retroviral delivery system |
ATE435297T1 (de) * | 1998-05-22 | 2009-07-15 | Oxford Biomedica Ltd | Retrovirales verabreichungssystem |
KR20000006334A (ko) * | 1998-06-26 | 2000-01-25 | 이선경 | 바이러스코딩염기서열이전혀없는고효율레트로바이러스벡터 |
EP1115290B1 (en) * | 1998-10-01 | 2009-03-04 | University of Southern California | Retroviral gene delivery system and methods of use |
IT1302403B1 (it) | 1998-11-06 | 2000-09-05 | Angeletti P Ist Richerche Bio | Cellule per la produzione di vettori adenovirali difettivi, metodoper la loro preparazione e loro uso. |
EP1046400B1 (en) * | 1999-04-20 | 2005-06-22 | Université Pierre et Marie Curie (Paris VI) | Use of an Equine herpes virus type-4 thymidine kinase and a nucleoside analog selected from ganciclovir and acyclovir for the killing of human proliferative cells |
WO2001055362A2 (en) * | 2000-01-31 | 2001-08-02 | The Governement Of The United States Of America, As Represented By The Secretary, Departement Of Health & Human Services, The National Institutes Of Health | Hybrid adeno-retroviral vector for the transfection of cells |
CA2402027A1 (en) * | 2000-03-08 | 2001-09-13 | Neurosearch A/S | A method of sensitising endothelial cells to prodrugs |
US20040235173A1 (en) * | 2000-07-03 | 2004-11-25 | Gala Design, Inc. | Production of host cells containing multiple integrating vectors by serial transduction |
US20030224415A1 (en) * | 2001-06-29 | 2003-12-04 | Gala Design, Inc. | Selection free growth of host cells containing multiple integrating vectors |
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US6852510B2 (en) | 2000-07-03 | 2005-02-08 | Gala Design Inc | Host cells containing multiple integrating vectors |
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EP1201750A1 (en) | 2000-10-26 | 2002-05-02 | Genopoietic | Synthetic viruses and uses thereof |
AU2001292310A1 (en) * | 2000-11-24 | 2002-06-03 | Chugai Seiyaku Kabushiki Kaisha | Method of regulating the activity of expression product of gene transferred intoliving body |
MXPA03005386A (es) | 2000-12-28 | 2004-04-20 | Wyeth Corp | Proteina protectora recombinante de streptococcus pneumoniae. |
WO2002061104A2 (en) * | 2001-01-30 | 2002-08-08 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Hybrid adenoviral vector |
EP1404842A2 (en) * | 2001-06-29 | 2004-04-07 | Novartis AG | Perv screening method and use thereof |
WO2003004088A2 (en) | 2001-07-05 | 2003-01-16 | Aventis Pharma S.A. | Method of administration of a gene of interest to the heart and vasculature |
US20040023910A1 (en) * | 2001-09-28 | 2004-02-05 | Zhiming Zhang | Use of cyr61 in the treatment and diagnosis of human uterine leiomyomas |
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
US7384738B2 (en) * | 2002-03-28 | 2008-06-10 | Bremel Robert D | Retrovirus-based genomic screening |
US20040038304A1 (en) * | 2002-03-28 | 2004-02-26 | Gala Design, Inc. | Antibody libraries |
US7785608B2 (en) | 2002-08-30 | 2010-08-31 | Wyeth Holdings Corporation | Immunogenic compositions for the prevention and treatment of meningococcal disease |
CN1482239A (zh) * | 2002-09-10 | 2004-03-17 | 本元正阳基因技术股份有限公司 | 用于生产慢病毒载体的人重组单纯疱疹病毒 |
US20050221429A1 (en) * | 2004-01-16 | 2005-10-06 | Cardinal Health Pts, Llc | Host cells containing multiple integrating vectors comprising an amplifiable marker |
AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
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MX350142B (es) | 2010-08-23 | 2017-08-28 | Wyeth Llc * | Formulaciones estables de antigenos rlp2086 de neisseria meningitidis. |
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WO2013063383A2 (en) | 2011-10-27 | 2013-05-02 | Wellstat Ophthalmics Corporation | Vectors encoding rod-derived cone viability factor |
KR101784644B1 (ko) | 2012-03-09 | 2017-10-11 | 화이자 인코포레이티드 | 수막염균 조성물 및 이의 사용 방법 |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
ES2786051T3 (es) | 2012-10-25 | 2020-10-08 | Tocagen Inc | Vector retroviral con casete de mini-promotor |
WO2014136064A2 (en) | 2013-03-08 | 2014-09-12 | Pfizer Inc. | Immunogenic fusion polypeptides |
US10981961B2 (en) | 2013-03-11 | 2021-04-20 | University Of Florida Research Foundation, Incorporated | Delivery of card protein as therapy for occular inflammation |
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EP3107939B1 (en) | 2014-02-19 | 2020-06-17 | University of Florida Research Foundation, Inc. | Delivery of nrf2 as therapy for protection against reactive oxygen species |
KR20170103009A (ko) | 2015-02-19 | 2017-09-12 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
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US5587308A (en) * | 1992-06-02 | 1996-12-24 | The United States Of America As Represented By The Department Of Health & Human Services | Modified adeno-associated virus vector capable of expression from a novel promoter |
US5834256A (en) * | 1993-06-11 | 1998-11-10 | Cell Genesys, Inc. | Method for production of high titer virus and high efficiency retroviral mediated transduction of mammalian cells |
US5714353A (en) * | 1994-05-24 | 1998-02-03 | Research Corporation Technologies, Inc. | Safe vectors for gene therapy |
-
1994
- 1994-12-15 FR FR9415135A patent/FR2716459B1/fr not_active Expired - Fee Related
-
1995
- 1995-02-22 DE DE69505493T patent/DE69505493T2/de not_active Expired - Lifetime
- 1995-02-22 EP EP98103971A patent/EP0855185A3/fr not_active Ceased
- 1995-02-22 AU AU18518/95A patent/AU1851895A/en not_active Abandoned
- 1995-02-22 JP JP52163795A patent/JP3681752B2/ja not_active Expired - Fee Related
- 1995-02-22 CA CA002183151A patent/CA2183151C/fr not_active Expired - Fee Related
- 1995-02-22 DK DK95910583T patent/DK0738327T3/da active
- 1995-02-22 WO PCT/FR1995/000208 patent/WO1995022617A1/fr active IP Right Grant
- 1995-02-22 ES ES95910583T patent/ES2124532T3/es not_active Expired - Lifetime
- 1995-02-22 IL IL11273695A patent/IL112736A0/xx unknown
- 1995-02-22 EP EP95910583A patent/EP0738327B1/fr not_active Expired - Lifetime
- 1995-02-22 AT AT95910583T patent/ATE172496T1/de active
- 1995-02-22 US US08/696,941 patent/US5948675A/en not_active Expired - Lifetime
-
1996
- 1996-08-13 NO NO963358A patent/NO963358L/no not_active Application Discontinuation
- 1996-08-19 FI FI963246A patent/FI963246A/fi unknown
-
1999
- 1999-05-06 US US09/306,422 patent/US20020051763A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69505493D1 (de) | 1998-11-26 |
EP0738327A1 (fr) | 1996-10-23 |
FR2716459B1 (fr) | 1996-05-10 |
EP0738327B1 (fr) | 1998-10-21 |
EP0855185A2 (fr) | 1998-07-29 |
FR2716459A1 (fr) | 1995-08-25 |
JPH09509060A (ja) | 1997-09-16 |
US5948675A (en) | 1999-09-07 |
ES2124532T3 (es) | 1999-02-01 |
CA2183151A1 (fr) | 1995-08-24 |
US20020051763A1 (en) | 2002-05-02 |
WO1995022617A1 (fr) | 1995-08-24 |
FI963246A0 (fi) | 1996-08-19 |
FI963246A (fi) | 1996-10-16 |
ATE172496T1 (de) | 1998-11-15 |
DE69505493T2 (de) | 1999-04-22 |
EP0855185A3 (fr) | 1998-11-18 |
IL112736A0 (en) | 1995-05-26 |
AU1851895A (en) | 1995-09-04 |
JP3681752B2 (ja) | 2005-08-10 |
DK0738327T3 (da) | 1999-06-28 |
NO963358D0 (no) | 1996-08-13 |
CA2183151C (fr) | 2008-12-09 |
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