NO962643L - Pyridazinonderivater samt fremgangsmåte til fremstilling av samme - Google Patents

Pyridazinonderivater samt fremgangsmåte til fremstilling av samme

Info

Publication number
NO962643L
NO962643L NO962643A NO962643A NO962643L NO 962643 L NO962643 L NO 962643L NO 962643 A NO962643 A NO 962643A NO 962643 A NO962643 A NO 962643A NO 962643 L NO962643 L NO 962643L
Authority
NO
Norway
Prior art keywords
preparing
well
same
pyridazinone derivatives
pyridazinone
Prior art date
Application number
NO962643A
Other languages
English (en)
Other versions
NO962643D0 (no
NO311084B1 (no
Inventor
Akihiko Ishada
Harutami Yamada
Michihisa Yato
Shinsuke Nishiyama
Fumikazu Okumura
Original Assignee
Tanabe Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co filed Critical Tanabe Seiyaku Co
Publication of NO962643D0 publication Critical patent/NO962643D0/no
Publication of NO962643L publication Critical patent/NO962643L/no
Publication of NO311084B1 publication Critical patent/NO311084B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D237/00Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Optical Couplings Of Light Guides (AREA)
NO19962643A 1995-06-27 1996-06-21 Pyridazinonforbindelse NO311084B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16062095 1995-06-27
JP1985996 1996-02-06

Publications (3)

Publication Number Publication Date
NO962643D0 NO962643D0 (no) 1996-06-21
NO962643L true NO962643L (no) 1996-12-30
NO311084B1 NO311084B1 (no) 2001-10-08

Family

ID=26356726

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19962643A NO311084B1 (no) 1995-06-27 1996-06-21 Pyridazinonforbindelse

Country Status (21)

Country Link
US (2) US5698554A (no)
EP (1) EP0751132B1 (no)
KR (1) KR970061873A (no)
CN (1) CN1144802A (no)
AR (1) AR002602A1 (no)
AT (1) ATE195937T1 (no)
AU (1) AU694955B2 (no)
BG (1) BG62768B1 (no)
CA (1) CA2179939A1 (no)
DE (1) DE69610036T2 (no)
DK (1) DK0751132T3 (no)
ES (1) ES2151110T3 (no)
GR (1) GR3034910T3 (no)
HU (1) HUP9601766A3 (no)
IL (1) IL118631A (no)
MY (1) MY132263A (no)
NO (1) NO311084B1 (no)
PT (1) PT751132E (no)
RU (1) RU2131419C1 (no)
SG (1) SG46741A1 (no)
TW (1) TW432052B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2235911C (en) * 1997-05-27 2003-07-29 Schneider (Usa) Inc. Stent and stent-graft for treating branched vessels
KR20030061051A (ko) * 2002-01-07 2003-07-18 대한민국 (경상대학교 총장) 신규한 아렌(혹은 알케인)술폰일피리다진온 유도체, 이의제조방법 및 유기반응에서의 용도
AR050552A1 (es) * 2004-09-02 2006-11-01 Osi Pharm Inc Mercaptoamidas como inhibidores de histona desacetilasa
CN101443317B (zh) * 2006-03-17 2011-07-06 住友化学株式会社 哒嗪酮化合物及其作为除草剂的用途
PL2069312T3 (pl) * 2006-07-25 2013-03-29 Cephalon Inc Pochodne pirydazynonu
US8268827B2 (en) * 2007-11-15 2012-09-18 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa. Pyridazinone derivatives as PARP inhibitors
WO2011116287A1 (en) * 2010-03-19 2011-09-22 Purdue Research Foundation Ccr5 modulators for treating hiv
MX340488B (es) 2010-11-05 2016-07-08 Senomyx Inc Compuestos utiles como moduladores de trpm8.
MX2013015058A (es) 2011-06-24 2014-01-20 Amgen Inc Antagonistas de melastatina 8 de potencial receptor transitorio y su uso en tratamientos.
CN103906733A (zh) 2011-06-24 2014-07-02 安姆根有限公司 Trpm8拮抗剂及其在治疗中的用途
WO2013097052A1 (en) 2011-12-30 2013-07-04 Abbott Laboratories Bromodomain inhibitors
US8952009B2 (en) 2012-08-06 2015-02-10 Amgen Inc. Chroman derivatives as TRPM8 inhibitors
CN108473484B (zh) 2015-10-01 2021-06-29 弗门尼舍公司 可用作trpm8调节剂的化合物
MA44674B1 (fr) 2016-04-15 2020-06-30 Abbvie Inc Inhibiteurs de bromodomaine
AU2019372121A1 (en) * 2018-10-30 2021-05-27 Nuvation Bio Inc. Heterocyclic compounds as BET inhibitors
EP3877376B1 (en) 2018-11-06 2023-08-23 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
BR112021026668A2 (pt) 2019-07-02 2022-02-15 Nuvation Bio Inc Compostos heterocíclicos como inibidores de bet

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6053022B2 (ja) * 1977-04-07 1985-11-22 ウェルファイド株式会社 ピリダジノン誘導体
GB8323553D0 (en) * 1983-09-02 1983-10-05 Smith Kline French Lab Pharmaceutical compositions
JPS6193169A (ja) * 1984-10-12 1986-05-12 Sankyo Co Ltd ピリダジノン誘導体及びその製法
EP0194548A3 (de) * 1985-03-12 1988-08-17 Dr. Karl Thomae GmbH Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE3508692A1 (de) 1985-03-12 1986-09-18 Dr. Karl Thomae Gmbh, 7950 Biberach 3-(4-(2-benzolsulfonylamino-aethyl)-benzoyl)propionsaeure, diese verbindung enthaltende arzneimittel und verfahren zu ihrer herstellung
KR860007219A (ko) * 1985-03-12 1986-10-08 베쩰, 좀머 설포닐아미노에틸 화합물의 제조방법
DE3623944A1 (de) 1986-07-16 1988-02-11 Thomae Gmbh Dr K Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
JPS63145272A (ja) * 1986-12-09 1988-06-17 Morishita Seiyaku Kk 4,5−ジヒドロ−6−(4−置換フエニル)−3(2h)−ピリダジノン誘導体
DE3728491A1 (de) * 1987-08-26 1989-03-09 Heumann Pharma Gmbh & Co Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE4134467A1 (de) * 1991-10-18 1993-04-22 Thomae Gmbh Dr K Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE69211133T2 (de) * 1991-03-01 1996-10-31 Zeria Pharmaceutical Co., Ltd., Tokio/Tokyo Indan-derivate als thromboxan-antagonisten
CA2099743A1 (en) * 1992-07-02 1994-01-03 Akihiko Ishida Pyridazinone derivatives and processes for preparing the same
JP2616584B2 (ja) * 1992-07-02 1997-06-04 田辺製薬株式会社 ピリダジノン誘導体及びその製法
CA2138812A1 (en) * 1993-12-28 1995-06-29 Akihiko Ishida Indane derivative and processes for preparing the same
CA2139088A1 (en) * 1993-12-28 1995-06-29 Akihiko Ishida Indane derivatives, processes for preparing the same and synthetic intermediate of the same
JP2757353B2 (ja) * 1993-12-28 1998-05-25 田辺製薬株式会社 インダン誘導体、その製法及びその合成中間体

Also Published As

Publication number Publication date
HUP9601766A2 (en) 1997-02-28
TW432052B (en) 2001-05-01
DK0751132T3 (da) 2000-11-13
US5808065A (en) 1998-09-15
ES2151110T3 (es) 2000-12-16
RU2131419C1 (ru) 1999-06-10
HUP9601766A3 (en) 1998-04-28
DE69610036D1 (de) 2000-10-05
NO962643D0 (no) 1996-06-21
EP0751132A1 (en) 1997-01-02
HU9601766D0 (en) 1996-08-28
AU694955B2 (en) 1998-08-06
EP0751132B1 (en) 2000-08-30
BG62768B1 (bg) 2000-07-31
DE69610036T2 (de) 2001-04-12
SG46741A1 (en) 1998-02-20
IL118631A (en) 2002-05-23
US5698554A (en) 1997-12-16
AR002602A1 (es) 1998-03-25
GR3034910T3 (en) 2001-02-28
KR970061873A (ko) 1997-09-12
CN1144802A (zh) 1997-03-12
BG100684A (bg) 1997-03-31
AU5622196A (en) 1997-01-09
MY132263A (en) 2007-09-28
NO311084B1 (no) 2001-10-08
IL118631A0 (en) 1996-10-16
CA2179939A1 (en) 1996-12-28
PT751132E (pt) 2000-12-29
ATE195937T1 (de) 2000-09-15

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