ATE195937T1 - Pyridazinone-derivate und verfahren zur deren herstellung - Google Patents
Pyridazinone-derivate und verfahren zur deren herstellungInfo
- Publication number
- ATE195937T1 ATE195937T1 AT96110412T AT96110412T ATE195937T1 AT E195937 T1 ATE195937 T1 AT E195937T1 AT 96110412 T AT96110412 T AT 96110412T AT 96110412 T AT96110412 T AT 96110412T AT E195937 T1 ATE195937 T1 AT E195937T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- pyridazinone derivatives
- pyridazinone
- derivatives
- Prior art date
Links
- AAILEWXSEQLMNI-UHFFFAOYSA-N 1h-pyridazin-6-one Chemical class OC1=CC=CN=N1 AAILEWXSEQLMNI-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
- C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
- C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D237/14—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Optical Couplings Of Light Guides (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP16062095 | 1995-06-27 | ||
| JP1985996 | 1996-02-06 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE195937T1 true ATE195937T1 (de) | 2000-09-15 |
Family
ID=26356726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96110412T ATE195937T1 (de) | 1995-06-27 | 1996-06-27 | Pyridazinone-derivate und verfahren zur deren herstellung |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5698554A (de) |
| EP (1) | EP0751132B1 (de) |
| KR (1) | KR970061873A (de) |
| CN (1) | CN1144802A (de) |
| AR (1) | AR002602A1 (de) |
| AT (1) | ATE195937T1 (de) |
| AU (1) | AU694955B2 (de) |
| BG (1) | BG62768B1 (de) |
| CA (1) | CA2179939A1 (de) |
| DE (1) | DE69610036T2 (de) |
| DK (1) | DK0751132T3 (de) |
| ES (1) | ES2151110T3 (de) |
| GR (1) | GR3034910T3 (de) |
| HU (1) | HUP9601766A3 (de) |
| IL (1) | IL118631A (de) |
| MY (1) | MY132263A (de) |
| NO (1) | NO311084B1 (de) |
| PT (1) | PT751132E (de) |
| RU (1) | RU2131419C1 (de) |
| SG (1) | SG46741A1 (de) |
| TW (1) | TW432052B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2235911C (en) * | 1997-05-27 | 2003-07-29 | Schneider (Usa) Inc. | Stent and stent-graft for treating branched vessels |
| DOP2000000070A (es) * | 1999-09-28 | 2002-02-28 | Bayer Healthcare Llc | Piridinas y piridacinas sustituidas con actividad de inhibición de angiogénesis |
| KR20030061051A (ko) * | 2002-01-07 | 2003-07-18 | 대한민국 (경상대학교 총장) | 신규한 아렌(혹은 알케인)술폰일피리다진온 유도체, 이의제조방법 및 유기반응에서의 용도 |
| AR050552A1 (es) * | 2004-09-02 | 2006-11-01 | Osi Pharm Inc | Mercaptoamidas como inhibidores de histona desacetilasa |
| CN101443317B (zh) * | 2006-03-17 | 2011-07-06 | 住友化学株式会社 | 哒嗪酮化合物及其作为除草剂的用途 |
| RS52626B (sr) | 2006-07-25 | 2013-06-28 | Cephalon Inc. | Derivati piridizinona |
| MX2010005070A (es) * | 2007-11-15 | 2010-05-24 | Angeletti P Ist Richerche Bio | Derivados de piridazinona como inhibidores de parp. |
| WO2011116287A1 (en) * | 2010-03-19 | 2011-09-22 | Purdue Research Foundation | Ccr5 modulators for treating hiv |
| CA2816983A1 (en) | 2010-11-05 | 2012-05-10 | Senomyx, Inc. | Compounds useful as modulators of trpm8 |
| EP2723717A2 (de) | 2011-06-24 | 2014-04-30 | Amgen Inc. | Trpm8-antagonisten und ihre verwendung bei behandlungen |
| AU2012272898A1 (en) | 2011-06-24 | 2013-04-11 | Amgen Inc. | TRPM8 antagonists and their use in treatments |
| WO2013097052A1 (en) | 2011-12-30 | 2013-07-04 | Abbott Laboratories | Bromodomain inhibitors |
| US8952009B2 (en) | 2012-08-06 | 2015-02-10 | Amgen Inc. | Chroman derivatives as TRPM8 inhibitors |
| US10392371B2 (en) | 2015-10-01 | 2019-08-27 | Senomyx, Inc. | Compounds useful as modulators of TRPM8 |
| RS60302B1 (sr) | 2016-04-15 | 2020-07-31 | Abbvie Inc | Inhibitori bromodomena |
| CN113226322A (zh) * | 2018-10-30 | 2021-08-06 | 诺维逊生物股份有限公司 | 作为bet抑制剂的杂环化合物 |
| CN113272280B (zh) | 2018-11-06 | 2026-01-09 | 艾知怀斯治疗学公司 | 哒嗪酮化合物及其用途 |
| JP7162132B2 (ja) | 2018-11-06 | 2022-10-27 | エッジワイズ セラピューティクス， インコーポレイテッド | ピリダジノン化合物およびその使用 |
| CA3118908A1 (en) | 2018-11-06 | 2020-05-14 | Edgewise Therapeutics, Inc. | Pyridazinone compounds and uses thereof |
| JP7465945B2 (ja) | 2019-07-02 | 2024-04-11 | ニューベイション・バイオ・インコーポレイテッド | Ｂｅｔ阻害剤としてのヘテロ環式化合物 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6053022B2 (ja) * | 1977-04-07 | 1985-11-22 | ウェルファイド株式会社 | ピリダジノン誘導体 |
| GB8323553D0 (en) * | 1983-09-02 | 1983-10-05 | Smith Kline French Lab | Pharmaceutical compositions |
| JPS6193169A (ja) * | 1984-10-12 | 1986-05-12 | Sankyo Co Ltd | ピリダジノン誘導体及びその製法 |
| DE3508692A1 (de) | 1985-03-12 | 1986-09-18 | Dr. Karl Thomae Gmbh, 7950 Biberach | 3-(4-(2-benzolsulfonylamino-aethyl)-benzoyl)propionsaeure, diese verbindung enthaltende arzneimittel und verfahren zu ihrer herstellung |
| EP0194548A3 (de) * | 1985-03-12 | 1988-08-17 | Dr. Karl Thomae GmbH | Neue Sulfonylaminoäthylverbindungen, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung |
| KR860007219A (ko) * | 1985-03-12 | 1986-10-08 | 베쩰, 좀머 | 설포닐아미노에틸 화합물의 제조방법 |
| DE3623944A1 (de) * | 1986-07-16 | 1988-02-11 | Thomae Gmbh Dr K | Neue benzolsulfonamido-indanylverbindungen, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| JPS63145272A (ja) * | 1986-12-09 | 1988-06-17 | Morishita Seiyaku Kk | ４，５−ジヒドロ−６−（４−置換フエニル）−３（２ｈ）−ピリダジノン誘導体 |
| SU1486061A3 (ru) * | 1987-03-26 | 1989-06-07 | Mitsubishi Chem Ind | Способ получения производных пиридазинона или их солей |
| DE3728491A1 (de) * | 1987-08-26 | 1989-03-09 | Heumann Pharma Gmbh & Co | Dihydropyridazinon-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE4134467A1 (de) * | 1991-10-18 | 1993-04-22 | Thomae Gmbh Dr K | Heterobiarylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung |
| JP2558208B2 (ja) * | 1991-03-01 | 1996-11-27 | ゼリア新薬工業株式会社 | インダン誘導体及び該化合物を含有するトロンボキサン拮抗剤 |
| CA2099743A1 (en) * | 1992-07-02 | 1994-01-03 | Akihiko Ishida | Pyridazinone derivatives and processes for preparing the same |
| JP2616584B2 (ja) * | 1992-07-02 | 1997-06-04 | 田辺製薬株式会社 | ピリダジノン誘導体及びその製法 |
| CA2139088A1 (en) * | 1993-12-28 | 1995-06-29 | Akihiko Ishida | Indane derivatives, processes for preparing the same and synthetic intermediate of the same |
| JP2757353B2 (ja) * | 1993-12-28 | 1998-05-25 | 田辺製薬株式会社 | インダン誘導体、その製法及びその合成中間体 |
| CA2138812A1 (en) * | 1993-12-28 | 1995-06-29 | Akihiko Ishida | Indane derivative and processes for preparing the same |
-
1996
- 1996-06-01 IL IL11863196A patent/IL118631A/en not_active IP Right Cessation
- 1996-06-21 NO NO19962643A patent/NO311084B1/no unknown
- 1996-06-26 TW TW085107678A patent/TW432052B/zh not_active IP Right Cessation
- 1996-06-26 SG SG1996010164A patent/SG46741A1/en unknown
- 1996-06-26 RU RU96112778/04A patent/RU2131419C1/ru not_active IP Right Cessation
- 1996-06-26 CA CA002179939A patent/CA2179939A1/en not_active Abandoned
- 1996-06-26 MY MYPI96002583A patent/MY132263A/en unknown
- 1996-06-26 HU HU9601766A patent/HUP9601766A3/hu unknown
- 1996-06-26 AR AR10332096A patent/AR002602A1/es unknown
- 1996-06-27 BG BG100684A patent/BG62768B1/bg unknown
- 1996-06-27 AU AU56221/96A patent/AU694955B2/en not_active Ceased
- 1996-06-27 US US08/671,485 patent/US5698554A/en not_active Expired - Fee Related
- 1996-06-27 ES ES96110412T patent/ES2151110T3/es not_active Expired - Lifetime
- 1996-06-27 AT AT96110412T patent/ATE195937T1/de not_active IP Right Cessation
- 1996-06-27 DE DE69610036T patent/DE69610036T2/de not_active Expired - Fee Related
- 1996-06-27 DK DK96110412T patent/DK0751132T3/da active
- 1996-06-27 PT PT96110412T patent/PT751132E/pt unknown
- 1996-06-27 EP EP96110412A patent/EP0751132B1/de not_active Expired - Lifetime
- 1996-06-27 CN CN96106873A patent/CN1144802A/zh active Pending
- 1996-06-27 KR KR1019960024718A patent/KR970061873A/ko not_active Ceased
-
1997
- 1997-08-25 US US08/917,113 patent/US5808065A/en not_active Expired - Fee Related
-
2000
- 2000-11-24 GR GR20000402616T patent/GR3034910T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| MY132263A (en) | 2007-09-28 |
| HUP9601766A3 (en) | 1998-04-28 |
| RU2131419C1 (ru) | 1999-06-10 |
| AU5622196A (en) | 1997-01-09 |
| SG46741A1 (en) | 1998-02-20 |
| US5698554A (en) | 1997-12-16 |
| DE69610036D1 (de) | 2000-10-05 |
| NO962643L (no) | 1996-12-30 |
| PT751132E (pt) | 2000-12-29 |
| DK0751132T3 (da) | 2000-11-13 |
| EP0751132A1 (de) | 1997-01-02 |
| IL118631A (en) | 2002-05-23 |
| IL118631A0 (en) | 1996-10-16 |
| DE69610036T2 (de) | 2001-04-12 |
| HUP9601766A2 (en) | 1997-02-28 |
| CN1144802A (zh) | 1997-03-12 |
| KR970061873A (ko) | 1997-09-12 |
| AR002602A1 (es) | 1998-03-25 |
| AU694955B2 (en) | 1998-08-06 |
| US5808065A (en) | 1998-09-15 |
| ES2151110T3 (es) | 2000-12-16 |
| TW432052B (en) | 2001-05-01 |
| GR3034910T3 (en) | 2001-02-28 |
| BG100684A (bg) | 1997-03-31 |
| NO962643D0 (no) | 1996-06-21 |
| NO311084B1 (no) | 2001-10-08 |
| BG62768B1 (bg) | 2000-07-31 |
| EP0751132B1 (de) | 2000-08-30 |
| CA2179939A1 (en) | 1996-12-28 |
| HU9601766D0 (en) | 1996-08-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59404480D1 (de) | Fullerenderivate, verfahren zur herstellung und deren verwendung | |
| DE69532895D1 (de) | Biomaterial und verfahren zu dessen herstellung | |
| DE69530312D1 (de) | Stabiles lycopin konzentrat und verfahren zu seiner herstellung | |
| DE69941054D1 (de) | Isosorbid enthaltende poyester und verfahren zu deren herstellung | |
| DE69623926D1 (de) | Kugelgelenk und verfahren zur herstellung | |
| DE69635345D1 (de) | Kautschukzusammensetzung und verfahren zu deren herstellung | |
| DE69535720D1 (de) | Faserstoffbahn und verfahren zur dessen herstellung | |
| DE69610226D1 (de) | Adsorptionsmedium und verfahren zur dessen herstellung | |
| DE69528111D1 (de) | Biosensor und Verfahren zur Herstellung desselben | |
| DE69804217D1 (de) | Dekorfolie und verfahren zu deren herstellung | |
| DE69720523D1 (de) | Polyolefin-polyethylenoxid-mischungen und verfahren zu deren herstellung | |
| DE69630732D1 (de) | Mehrzelliges Dämpfungselement und Verfahren zur dessen Herstellung | |
| DE69511714D1 (de) | Fahrzeugfenster und verfahren zu dessen herstellung | |
| DE69616516D1 (de) | Wasserschutzzusammensetzungen und verfahren zu deren herstellung | |
| DE69715661D1 (de) | Verfahren und anlage zur herstellung von methanol | |
| DE69530954D1 (de) | Mikromechanisches Bauelement und Verfahren zur Herstellung desselben | |
| DE69710484D1 (de) | Übergezogene süsswaren und verfahren zu deren herstellung | |
| ATE195937T1 (de) | Pyridazinone-derivate und verfahren zur deren herstellung | |
| DE69815126D1 (de) | Pyrimidinderivate und verfahren zu deren herstellung | |
| DE19681517T1 (de) | Dekorationsfolie und Verfahren zur Herstellung derselben | |
| DE59603734D1 (de) | Integrales plattenförmiges bauteil und verfahren zu seiner herstellung | |
| DE69519739D1 (de) | Epdm zusammensetzungen und verfahren zur herstellung davon | |
| ATE262532T1 (de) | Substituierte camptothecinderivate und verfahren zur ihrer herstellung | |
| DE69608359D1 (de) | Hexaazaisowurtzitan-derivate und verfahren zu deren herstellung | |
| DE69503332D1 (de) | Gleitstück und verfahren zu dessen herstellung |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |