NO961521D0 - Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner - Google Patents

Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner

Info

Publication number
NO961521D0
NO961521D0 NO961521A NO961521A NO961521D0 NO 961521 D0 NO961521 D0 NO 961521D0 NO 961521 A NO961521 A NO 961521A NO 961521 A NO961521 A NO 961521A NO 961521 D0 NO961521 D0 NO 961521D0
Authority
NO
Norway
Prior art keywords
indenoylguanidines
antiarrhythmic
cardioprotective
substituted
useful
Prior art date
Application number
NO961521A
Other languages
English (en)
Other versions
NO305655B1 (no
NO961521L (no
Inventor
Nirogi Venkata Sat Ramakrishna
Tulsidas Sitaram More
Anagha Suhas Kulkarni
Bansi Lal
Roa Venkata Satya Ve Vadlamudi
Anil Vasantrao Ghate
Ravindra Dattatraya Gupte
Wolfgang Scholz
Hans-Jochen Lang
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO961521D0 publication Critical patent/NO961521D0/no
Publication of NO961521L publication Critical patent/NO961521L/no
Publication of NO305655B1 publication Critical patent/NO305655B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Optical Record Carriers And Manufacture Thereof (AREA)
NO961521A 1995-04-18 1996-04-17 Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner, deres anvendelse for fremstilling av legemidler, samt legemiddel inneholdende disse NO305655B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP95105724 1995-04-18
US08/633,223 US5733934A (en) 1995-04-18 1996-04-16 Antiarrythmic and cardioprotective substituted indenoylguanidines

Publications (3)

Publication Number Publication Date
NO961521D0 true NO961521D0 (no) 1996-04-17
NO961521L NO961521L (no) 1996-10-21
NO305655B1 NO305655B1 (no) 1999-07-05

Family

ID=26138562

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961521A NO305655B1 (no) 1995-04-18 1996-04-17 Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner, deres anvendelse for fremstilling av legemidler, samt legemiddel inneholdende disse

Country Status (23)

Country Link
US (1) US5733934A (no)
EP (1) EP0738712B1 (no)
JP (1) JPH08291131A (no)
CN (1) CN1061648C (no)
AT (1) ATE183498T1 (no)
AU (1) AU706055B2 (no)
BR (1) BR9601989A (no)
CA (1) CA2174406A1 (no)
CZ (1) CZ291538B6 (no)
DE (1) DE69603771T2 (no)
DK (1) DK0738712T3 (no)
ES (1) ES2135811T3 (no)
GR (1) GR3031540T3 (no)
HU (1) HUP9600998A3 (no)
IL (1) IL117927A (no)
NO (1) NO305655B1 (no)
NZ (1) NZ286380A (no)
PL (1) PL182566B1 (no)
RU (1) RU2182902C2 (no)
SI (1) SI0738712T1 (no)
SK (1) SK282011B6 (no)
TR (1) TR199600316A1 (no)
ZA (1) ZA963046B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002502414A (ja) * 1997-06-02 2002-01-22 藤沢薬品工業株式会社 細胞中のＮａ▲上＋▼／Ｈ▲上＋▼交換の阻害剤としてのグアニジン誘導体
US6160134A (en) * 1997-12-24 2000-12-12 Bristol-Myers Squibb Co. Process for preparing chiral cyclopropane carboxylic acids and acyl guanidines
US6011059A (en) * 1997-12-24 2000-01-04 Bristol-Myers Squibb Company Acyl guanidine sodium/proton exchange inhibitors and method
TW462964B (en) * 1998-05-26 2001-11-11 Sumitomo Pharma Guanidine derivatives for the treatment and prevention of disorders caused by inhibiting hyperactivity of Na/H exchange transport system and process for producing the same
DE19859727A1 (de) 1998-12-23 2000-06-29 Aventis Pharma Gmbh Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
JP2002542291A (ja) 1999-04-23 2002-12-10 ブリストル−マイヤーズ スクイブ カンパニー ジ環式アシルグアニジン・ナトリウム／プロトン交換抑制剤および方法
EP2617709B8 (en) * 2003-06-26 2022-12-21 Biotron Limited Guanidine derivatives as antiviral agents
US20070099968A1 (en) * 2004-06-26 2007-05-03 Biotron Limited Antiviral compounds and methods

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2734904A (en) * 1956-02-14 Xcxnhxc-nh
US3780027A (en) * 1970-04-29 1973-12-18 Merck & Co Inc Anthranilic acid derivatives
US4544670A (en) * 1982-08-24 1985-10-01 William H. Rorer, Inc. Method of treating coccidiosis with acyl guanidines
EP0556673B1 (de) * 1992-02-15 1997-09-17 Hoechst Aktiengesellschaft Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4326005A1 (de) * 1993-08-03 1995-02-09 Hoechst Ag Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament
EP0639573A1 (de) * 1993-08-03 1995-02-22 Hoechst Aktiengesellschaft Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
MX9601424A (es) 1997-07-31
CA2174406A1 (en) 1996-10-19
HUP9600998A2 (en) 1997-01-28
ZA963046B (en) 1996-10-22
HU9600998D0 (en) 1996-06-28
GR3031540T3 (en) 2000-01-31
BR9601989A (pt) 1998-04-07
CZ291538B6 (cs) 2003-03-12
IL117927A (en) 2001-12-23
SK48396A3 (en) 1996-12-04
HUP9600998A3 (en) 1997-11-28
AU5067696A (en) 1996-10-31
ES2135811T3 (es) 1999-11-01
DE69603771D1 (de) 1999-09-23
CZ109696A3 (en) 1996-11-13
IL117927A0 (en) 1996-08-04
TR199600316A1 (tr) 1997-03-21
SI0738712T1 (en) 1999-12-31
NZ286380A (en) 1997-09-22
PL182566B1 (pl) 2002-01-31
CN1061648C (zh) 2001-02-07
AU706055B2 (en) 1999-06-10
EP0738712A1 (en) 1996-10-23
CN1140164A (zh) 1997-01-15
DE69603771T2 (de) 2000-09-07
SK282011B6 (sk) 2001-10-08
RU2182902C2 (ru) 2002-05-27
ATE183498T1 (de) 1999-09-15
NO305655B1 (no) 1999-07-05
NO961521L (no) 1996-10-21
US5733934A (en) 1998-03-31
DK0738712T3 (da) 2000-03-06
JPH08291131A (ja) 1996-11-05
EP0738712B1 (en) 1999-08-18

Similar Documents

Publication Publication Date Title
DE68920125T2 (de) Pyrimidindion-Derivate, Verfahren zu deren Herstellung und diese enthaltende antiarrythmische Mittel.
DK0379979T3 (no)
HUT47217A (en) Process for producing pharmaceutical compositions containing indol derivatives as active components
DK0430045T3 (da) Ascorbinsyretocopherylphosphatdiestere til hæmning af Maillards reaktion
IT1229570B (it) Derivati fluorurati di acidi biliari, loro preparazione e composizioni farmaceutiche che li contengono.
RU94037246A (ru) Применение 2-фенил-3-ароилбензотиофенов для ингибирования разрушения хряща
NO961521L (no) Antiarytmiske og kardiobeskyttende substituerte indenoylguanidiner
ATE2423T1 (de) 1-acyloxyphenyl-1,2-diphenylalken-derivate, verfahren zu deren herstellung und eine diese derivate enthaltende pharmazeutische zusammensetzung.
IL97855A0 (en) Bromide containing pharmaceutical compositions for treatment of psoriasis
HUT49283A (en) Process for production of medical compositions applicable for treatment of peptical ulcer
CA1268468C (en) PROSTAGLANDIN ANALOGS WITH SUBSTITUTE THIABICYCLOHEPTAN GROUP
HK1067948A1 (en) Antitumor indolopyprolocarbazole derivative
AR004481A1 (es) Indenoilguanidinas sustituidas antiarritmicas y cardioprotectoras
ATE21908T1 (de) Derivate von 1,4-diaminocyclitol, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ATE109454T1 (de) Catecholaminester.
MX9606397A (es) Cromanilsulfonil(tio)ureas sustituidas, procedimientos para prepararlas, y su utilizacion en preparados farmaceuticos, asi como preparados farmaceuticos que las contienen.
RU92016472A (ru) Противовирусные средства, содержащие гетерополимолибдаты, способ лечения или профилактики инфекций, связанных с ретровирусом, применение гетерополимолибдатов для получения лекарственных средств, гетерополимолибдаты

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees