NO953437L - Inhibitorer for Herpes virus ribonukleotid-reduktase - Google Patents

Inhibitorer for Herpes virus ribonukleotid-reduktase

Info

Publication number
NO953437L
NO953437L NO953437A NO953437A NO953437L NO 953437 L NO953437 L NO 953437L NO 953437 A NO953437 A NO 953437A NO 953437 A NO953437 A NO 953437A NO 953437 L NO953437 L NO 953437L
Authority
NO
Norway
Prior art keywords
alkyl
nhch
amino acid
inhibitors
herpes virus
Prior art date
Application number
NO953437A
Other languages
English (en)
Norwegian (no)
Other versions
NO953437D0 (no
Inventor
Robert Deziel
Neil Moss
Original Assignee
Bio Mega Boehringer Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bio Mega Boehringer Ingelheim filed Critical Bio Mega Boehringer Ingelheim
Publication of NO953437D0 publication Critical patent/NO953437D0/no
Publication of NO953437L publication Critical patent/NO953437L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • A61P31/22Antivirals for DNA viruses for herpes viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16611Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO953437A 1993-03-03 1995-09-01 Inhibitorer for Herpes virus ribonukleotid-reduktase NO953437L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2554093A 1993-03-03 1993-03-03
PCT/CA1994/000106 WO1994020528A1 (en) 1993-03-03 1994-02-28 Inhibitors of herpes viral ribonucleotide reductase

Publications (2)

Publication Number Publication Date
NO953437D0 NO953437D0 (no) 1995-09-01
NO953437L true NO953437L (no) 1995-09-01

Family

ID=21826675

Family Applications (1)

Application Number Title Priority Date Filing Date
NO953437A NO953437L (no) 1993-03-03 1995-09-01 Inhibitorer for Herpes virus ribonukleotid-reduktase

Country Status (27)

Country Link
US (1) US5476841A (cs)
EP (1) EP0618226B1 (cs)
JP (1) JPH08507760A (cs)
KR (1) KR960701090A (cs)
CN (1) CN1118601A (cs)
AT (1) ATE197802T1 (cs)
AU (1) AU683450B2 (cs)
BG (1) BG99889A (cs)
BR (1) BR9406346A (cs)
CA (1) CA2157196C (cs)
CZ (1) CZ224295A3 (cs)
DE (1) DE69426337T2 (cs)
DK (1) DK0618226T3 (cs)
ES (1) ES2152269T3 (cs)
FI (1) FI954048A0 (cs)
GR (1) GR3035295T3 (cs)
HU (1) HUT72894A (cs)
IL (1) IL108818A0 (cs)
LV (1) LV11037B (cs)
NO (1) NO953437L (cs)
NZ (1) NZ262073A (cs)
PL (1) PL310447A1 (cs)
PT (1) PT618226E (cs)
SG (1) SG65553A1 (cs)
SK (1) SK106095A3 (cs)
WO (1) WO1994020528A1 (cs)
ZA (1) ZA941449B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5846941A (en) * 1992-03-12 1998-12-08 Boehringer Ingelheim (Canada) Ltd. Isosteric antiherpes peptide derivatives II
US5830864A (en) * 1992-03-12 1998-11-03 Boehringer Ingelheim (Canada), Ltd. Antiherpes peptide derivatives having a ureido n-terminus
CA2152541C (en) * 1995-06-23 1998-12-15 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Herpes ribonucleotide reductase inhibitors
US5948935A (en) * 1997-01-23 1999-09-07 Boehringer Ingelheim (Canada) Ltd. Process and intermediates for (s)-α-amino-1-carboxycyclopentaneacetic acid
US8029815B2 (en) * 2004-04-28 2011-10-04 Elford Howard L Methods for treating or preventing restenosis and other vascular proliferative disorders
EP2030615A3 (en) * 2007-08-13 2009-12-02 ELFORD, Howard L. Ribonucleotide reductase inhibitors for use in the treatment or prevention of neuroinflammatory or autoimmune diseases
US20250057849A1 (en) * 2021-12-22 2025-02-20 Cj Cheiljedang Corporation Antiviral composition comprising nucleoside analogues derived from nucleic acid and pharmaceutically acceptable salt thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69017113T2 (de) * 1989-07-07 1995-08-03 Bio Mega Boehringer Ingelheim Pentapeptidderivate, wirksam gegen Herpes, die eine ersetzte Asparaginsäureseitenkette enthalten.
JPH03181498A (ja) * 1989-12-07 1991-08-07 Merck & Co Inc ペプチド抗ウイルス剤
CA2033448C (en) * 1990-12-31 1996-11-26 Boehringer Ingelheim (Canada) Ltd./ Boehringer Ingelheim (Canada) Ltee Antiherpes compositions and method of use

Also Published As

Publication number Publication date
AU683450B2 (en) 1997-11-13
DE69426337T2 (de) 2001-05-31
BR9406346A (pt) 1996-02-21
ES2152269T3 (es) 2001-02-01
ATE197802T1 (de) 2000-12-15
FI954048L (fi) 1995-08-29
IL108818A0 (en) 1994-06-24
WO1994020528A1 (en) 1994-09-15
KR960701090A (ko) 1996-02-24
FI954048A7 (fi) 1995-08-29
CN1118601A (zh) 1996-03-13
HU9502570D0 (en) 1995-11-28
ZA941449B (en) 1994-10-14
CA2157196C (en) 2000-06-13
BG99889A (bg) 1996-02-28
US5476841A (en) 1995-12-19
FI954048A0 (fi) 1995-08-29
SK106095A3 (en) 1996-02-07
EP0618226A1 (en) 1994-10-05
SG65553A1 (en) 1999-06-22
AU6151694A (en) 1994-09-26
NZ262073A (en) 1997-07-27
DE69426337D1 (de) 2001-01-04
LV11037A (lv) 1996-02-20
DK0618226T3 (da) 2000-12-27
JPH08507760A (ja) 1996-08-20
PT618226E (pt) 2001-03-30
EP0618226B1 (en) 2000-11-29
CZ224295A3 (en) 1996-02-14
NO953437D0 (no) 1995-09-01
HUT72894A (en) 1996-06-28
GR3035295T3 (en) 2001-04-30
LV11037B (en) 1996-06-20
CA2157196A1 (en) 1994-09-15
PL310447A1 (en) 1995-12-11

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