NO951370L - Fremgangsmåte ved fremstilling av medikamentpelleter - Google Patents

Fremgangsmåte ved fremstilling av medikamentpelleter

Info

Publication number
NO951370L
NO951370L NO951370A NO951370A NO951370L NO 951370 L NO951370 L NO 951370L NO 951370 A NO951370 A NO 951370A NO 951370 A NO951370 A NO 951370A NO 951370 L NO951370 L NO 951370L
Authority
NO
Norway
Prior art keywords
rotor
granulating liquid
pellets
preparing drug
drug pellets
Prior art date
Application number
NO951370A
Other languages
English (en)
Norwegian (no)
Other versions
NO951370D0 (no
Inventor
Leena Hellen
Isabelle Husson
Eeva Kristoffersson
Jouko Yliruusi
Original Assignee
Leena Hellen
Isabelle Husson
Eeva Kristoffersson
Jouko Yliruusi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leena Hellen, Isabelle Husson, Eeva Kristoffersson, Jouko Yliruusi filed Critical Leena Hellen
Publication of NO951370D0 publication Critical patent/NO951370D0/no
Publication of NO951370L publication Critical patent/NO951370L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/003Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic followed by coating of the granules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/10Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic in stationary drums or troughs, provided with kneading or mixing appliances
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/20Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic by expressing the material, e.g. through sieves and fragmenting the extruded length
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2/00Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
    • B01J2/30Processes or devices for granulating materials, e.g. fertilisers in general; Rendering particulate materials free flowing in general, e.g. making them hydrophobic using agents to prevent the granules sticking together; Rendering particulate materials free flowing in general, e.g. making them hydrophobic
NO951370A 1992-10-09 1995-04-07 Fremgangsmåte ved fremstilling av medikamentpelleter NO951370L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI924590A FI101039B (sv) 1992-10-09 1992-10-09 Förfarande för framställning av läkemedelskorn
PCT/FI1993/000409 WO1994008567A1 (en) 1992-10-09 1993-10-08 Process for the preparation of drug pellets

Publications (2)

Publication Number Publication Date
NO951370D0 NO951370D0 (no) 1995-04-07
NO951370L true NO951370L (no) 1995-06-08

Family

ID=8536020

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951370A NO951370L (no) 1992-10-09 1995-04-07 Fremgangsmåte ved fremstilling av medikamentpelleter

Country Status (9)

Country Link
US (1) US5709885A (sv)
EP (1) EP0662823A1 (sv)
JP (1) JPH08502675A (sv)
AU (1) AU5112993A (sv)
CA (1) CA2146536A1 (sv)
FI (1) FI101039B (sv)
NO (1) NO951370L (sv)
WO (1) WO1994008567A1 (sv)
ZA (1) ZA937483B (sv)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2721512A1 (fr) * 1994-06-28 1995-12-29 Maurice Jacob Formulation et procédé de préparation de sphéroïdes à base de solutions d'origine végétale.
EP1014941B2 (en) 1996-06-26 2017-05-17 The Board Of Regents, The University Of Texas System Hot-melt extrudable pharmaceutical formulation
AUPP148398A0 (en) 1998-01-23 1998-02-19 Crop Care Australasia Pty Ltd Granulator
US6074689A (en) * 1998-03-10 2000-06-13 Immucell Corporation Colonic delivery of protein or peptide compositions
US6524620B2 (en) 1998-07-20 2003-02-25 Andrx Pharmaceuticals, Inc. Diltiazem controlled release formulation and method of manufacture
WO2000045734A1 (en) 1999-02-02 2000-08-10 Wright Medical Technology, Inc. Controlled release composite
MXPA02009534A (es) 2000-03-30 2003-05-14 Squibb Bristol Myers Co Granulos de liberacion sostenida que contienen estavudina.
FR2814366A1 (fr) * 2000-09-22 2002-03-29 Rhodia Chimie Sa Procede de granulation de matieres actives par extrusion basse pression pour l'obtention de granules directement compressibles
US7776314B2 (en) 2002-06-17 2010-08-17 Grunenthal Gmbh Abuse-proofed dosage system
KR100510270B1 (ko) * 2002-11-29 2005-08-26 센츄론(주) 펠렛타이저를 이용한 서방성 제제의 제조방법
US9107804B2 (en) * 2002-12-10 2015-08-18 Nortec Development Associates, Inc. Method of preparing biologically active formulations
DE10336400A1 (de) 2003-08-06 2005-03-24 Grünenthal GmbH Gegen Missbrauch gesicherte Darreichungsform
DE102005005446A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Bruchfeste Darreichungsformen mit retardierter Freisetzung
DE102004032051A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
US20070048228A1 (en) 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
DE10361596A1 (de) 2003-12-24 2005-09-29 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
EP1753405A4 (en) * 2004-06-10 2008-09-17 Glatt Air Tech Inc SLOW RELEASE PHARMACEUTICAL PREPARATION
DE102004032049A1 (de) 2004-07-01 2006-01-19 Grünenthal GmbH Gegen Missbrauch gesicherte, orale Darreichungsform
DE102005005449A1 (de) 2005-02-04 2006-08-10 Grünenthal GmbH Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
MX2007015377A (es) * 2005-06-08 2008-02-14 Orion Corp Forma de dosificacion oral.
US20070036859A1 (en) * 2005-08-11 2007-02-15 Perry Ronald L Sustained release antihistamine and decongestant composition
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
KR101616246B1 (ko) 2008-01-25 2016-05-02 그뤼넨탈 게엠베하 약제학적 투여형
MX2010012039A (es) 2008-05-09 2010-11-30 Gruenenthal Gmbh Proceso para la preparacion de una formulacion de polvo intermedia y una forma de dosificacion solida final bajo el uso de un paso de congelacion por rocio.
CN101744725B (zh) * 2008-12-09 2013-04-17 北京华素制药股份有限公司 缓释微丸包衣生产工艺参数的优化方法
GB0907413D0 (en) 2009-04-29 2009-06-10 Equateq Ltd Novel methods
RU2015138422A (ru) 2009-07-22 2018-12-25 Грюненталь Гмбх Стабильная при окислении, прочная на излом лекарственная форма
MX2012000317A (es) 2009-07-22 2012-02-08 Gruenenthal Gmbh Forma de dosificacion de liberacion controlada extruida por fusion en caliente.
CA2808219C (en) 2010-09-02 2019-05-14 Gruenenthal Gmbh Tamper resistant dosage form comprising inorganic salt
ES2487244T3 (es) 2010-09-02 2014-08-20 Grünenthal GmbH Forma de dosificación resistente a la manipulación que comprende un polímero aniónico
CA2839123A1 (en) 2011-07-29 2013-02-07 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
AU2012292418B2 (en) 2011-07-29 2017-02-16 Grunenthal Gmbh Tamper-resistant tablet providing immediate drug release
MX356421B (es) 2012-02-28 2018-05-29 Gruenenthal Gmbh Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
CN104394851B (zh) 2012-04-18 2017-12-01 格吕伦塔尔有限公司 抗篡改和抗剂量‑倾泻药物剂型
US10064945B2 (en) 2012-05-11 2018-09-04 Gruenenthal Gmbh Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
CA2907950A1 (en) 2013-05-29 2014-12-04 Grunenthal Gmbh Tamper-resistant dosage form containing one or more particles
AR096438A1 (es) 2013-05-29 2015-12-30 Gruenenthal Gmbh Forma de dosificación resistente al uso indebido con perfil de liberación bimodal, proceso
BR112016000194A8 (pt) 2013-07-12 2019-12-31 Gruenenthal Gmbh forma de dosagem resistente à violação contendo o polímero de acetato de etileno-vinila
CN105934241B (zh) 2013-11-26 2020-06-05 格吕伦塔尔有限公司 通过低温研磨制备粉末状药物组合物
WO2015173195A1 (en) 2014-05-12 2015-11-19 Grünenthal GmbH Tamper resistant immediate release capsule formulation comprising tapentadol
JP2017516789A (ja) 2014-05-26 2017-06-22 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング エタノール過量放出に対して防護されている多粒子
RU2020101477A (ru) 2014-06-04 2020-06-19 Дигнити Сайенсиз Лимитед Фармацевтические композиции, содержащие дглк, и их применение
EP3285745A1 (en) 2015-04-24 2018-02-28 Grünenthal GmbH Tamper-resistant dosage form with immediate release and resistance against solvent extraction
CA2998259A1 (en) 2015-09-10 2017-03-16 Grunenthal Gmbh Protecting oral overdose with abuse deterrent immediate release formulations
JP2017132716A (ja) * 2016-01-27 2017-08-03 ライオン株式会社 錠剤の製造方法
CN109925290B (zh) * 2017-12-18 2021-03-16 广州白云山明兴制药有限公司 茶碱缓释片及其制备工艺

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2470599A1 (fr) * 1979-12-07 1981-06-12 Panoz Donald Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus
JPS5949840A (ja) * 1982-09-14 1984-03-22 Taiyo Yakuhin Kogyo Kk 顆粒、細粒の固着防止方法
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
GB8702411D0 (en) * 1987-02-03 1987-03-11 Zyma Sa Swellable pellets
HU206828B (en) * 1989-08-10 1993-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing veterinary compositions containing benzimidazol derivatives as active components
DK162506C (da) * 1989-12-22 1992-03-30 Ferrosan As Fremgangsmaade til fremstilling af et tabletterbart granulat
IT1243390B (it) * 1990-11-22 1994-06-10 Vectorpharma Int Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
GB9119052D0 (en) * 1991-09-06 1991-10-23 Boots Co Plc Pharmaceutical compositions
WO1993007859A1 (en) * 1991-10-23 1993-04-29 Warner-Lambert Company Novel pharmaceutical pellets and process for their production

Also Published As

Publication number Publication date
FI101039B (sv) 1998-04-15
AU5112993A (en) 1994-05-09
US5709885A (en) 1998-01-20
FI924590A (fi) 1994-04-10
NO951370D0 (no) 1995-04-07
FI924590A0 (fi) 1992-10-09
ZA937483B (en) 1994-04-26
CA2146536A1 (en) 1994-04-28
JPH08502675A (ja) 1996-03-26
WO1994008567A1 (en) 1994-04-28
EP0662823A1 (en) 1995-07-19

Similar Documents

Publication Publication Date Title
NO951370L (no) Fremgangsmåte ved fremstilling av medikamentpelleter
CA2091370A1 (en) Tablets, granulates and pellets with a high active substance content for highly concentrated, solid dosage forms
WO1997036996A3 (en) Process for the preparation of a granular microbial biomass and isolation of valuable compounds therefrom
DE69832621D1 (de) Pharmazeutische formulierungen mit kontrollierter freigabe von wirkstoffen
AU2054188A (en) Skin treatment composition
AU4657085A (en) High density, delayed release lacquered pharmaceutical pellets
NO20001670L (no) Fremgangsmate for fremstilling av en smaksmaskert farmasoytisk blanding og smaksmaskert farmasoytisk blanding fremstilt ifolge denne fremgangsmaten, samt smaksmaskerte tyggbare tabletter
MX9206952A (es) Polvo de dispercion redispersable a partir de un copolimerizado de acetato de vinilo de n-vinilpirrolidona su preparcion y su empleo
SE8603247D0 (sv) Farmaceutiskt granulat
DE3772072D1 (de) Pharmazeutische zusammensetzung.
DK459486D0 (da) Vitaminholdigt granulat, fremstilling deraf og tabletter fremstillet deraf
NO963678L (no) Fremgangsmåte for fremstilling av preparat med vedvarende frigiving
WO1993009176A3 (en) Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
EP0171528A3 (en) Controlled release pharmaceutical preparations
DK1171111T3 (da) Granulat, som har højt indhold af L-carnitin eller et alkanoyl L-carnitin, og som er særlig egnet til fremstilling af tabletter ved direkte presning
MX9305539A (es) Procedimiento para la fabricacion de pellets a partir de un derivado de efedrina.
ATE77049T1 (de) Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe.
AU8989991A (en) Salinomycin biomass granules which are free-flowing and dust-free and have unrestricted bioavailability of active substance, and a process for the production thereof
DK557587A (da) Fremgangsmaade til fremstilling af et bindemiddelfrit celiprolol-hydrochlorid-granulat, der let lader sig presse til tabletter
HUP0100752A2 (hu) Eljárás bevont, gömbölyű granulátumszemcsék előállítására
JPS57137317A (en) Production of sealing cell
JPS5282715A (en) Long acting drug composition
KR930011874A (ko) 과립마늘제품의 제조방법
JPS5259650A (en) Preparation of granular composite stabilizer for polyvinyl chloride
HUP0500512A2 (hu) Megnövelt dózisú nelfinavir tabletta és eljárás a tabletta előállítására