NO942095L - Imidazopyridiner - Google Patents
ImidazopyridinerInfo
- Publication number
- NO942095L NO942095L NO942095A NO942095A NO942095L NO 942095 L NO942095 L NO 942095L NO 942095 A NO942095 A NO 942095A NO 942095 A NO942095 A NO 942095A NO 942095 L NO942095 L NO 942095L
- Authority
- NO
- Norway
- Prior art keywords
- well
- imidazopyridines
- aldosteronism
- angiotensin
- salts
- Prior art date
Links
- 150000005232 imidazopyridines Chemical class 0.000 title 1
- 102000005862 Angiotensin II Human genes 0.000 abstract 1
- 101800000733 Angiotensin-2 Proteins 0.000 abstract 1
- 206010019280 Heart failures Diseases 0.000 abstract 1
- 206010020571 Hyperaldosteronism Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 abstract 1
- 229950006323 angiotensin ii Drugs 0.000 abstract 1
- 230000003042 antagnostic effect Effects 0.000 abstract 1
- 208000015114 central nervous system disease Diseases 0.000 abstract 1
- 125000004857 imidazopyridinyl group Chemical class N1C(=NC2=C1C=CC=N2)* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Ophthalmology & Optometry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Reproductive Health (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4318813A DE4318813A1 (de) | 1993-06-07 | 1993-06-07 | Imidazopyridine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO942095D0 NO942095D0 (no) | 1994-06-06 |
| NO942095L true NO942095L (no) | 1994-12-08 |
Family
ID=6489765
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO942095A NO942095L (no) | 1993-06-07 | 1994-06-06 | Imidazopyridiner |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5438063A (fa) |
| EP (1) | EP0628556A1 (fa) |
| JP (1) | JPH072854A (fa) |
| KR (1) | KR950000697A (fa) |
| CN (1) | CN1100721A (fa) |
| AU (1) | AU689468B2 (fa) |
| CA (1) | CA2125077A1 (fa) |
| CZ (1) | CZ137694A3 (fa) |
| DE (1) | DE4318813A1 (fa) |
| HU (1) | HUT71483A (fa) |
| NO (1) | NO942095L (fa) |
| PL (1) | PL303715A1 (fa) |
| RU (1) | RU94019981A (fa) |
| SK (1) | SK67794A3 (fa) |
| TW (1) | TW269689B (fa) |
| ZA (1) | ZA943996B (fa) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2708612B1 (fr) * | 1993-08-05 | 1996-03-01 | Roussel Uclaf | Nouveaux dérivés bicycliques de l'imidazole, leur procédé de préparation, les nouveaux intermédiaires obtenus, leur application à titre de médicaments et les compositions pharmaceutiques les renfermant. |
| DE4432860A1 (de) * | 1994-09-15 | 1996-03-21 | Merck Patent Gmbh | Imidazopyridine |
| PT930076E (pt) * | 1996-07-15 | 2005-01-31 | Sankyo Co | Composicoes medicinais |
| DE19845153A1 (de) * | 1998-10-01 | 2000-04-06 | Merck Patent Gmbh | Imidazo[4,5]-pyridin-4-on-derivate |
| GB0215293D0 (en) | 2002-07-03 | 2002-08-14 | Rega Foundation | Viral inhibitors |
| EP1558581A4 (en) | 2002-10-07 | 2007-07-25 | Bristol Myers Squibb Co | DERIVATIVES OF TRIAZOLONE AND TRIAZOLETHIONE |
| EP1706403B9 (en) | 2003-12-22 | 2012-07-25 | K.U.Leuven Research & Development | Imidazo[4,5-c]pyridine compounds and methods of antiviral treatment |
| US20060252791A1 (en) | 2004-12-21 | 2006-11-09 | Gilead Sciences, Inc. | Imidazo[4,5-c]pyridine compound and method of antiviral treatment |
| HRP20080552A9 (en) * | 2005-03-30 | 2009-08-31 | Takeda Pharmaceutical Company Limited | Benzimidazole derivative and use thereof |
| TWI360549B (en) | 2006-07-07 | 2012-03-21 | Gilead Sciences Inc | Novel pyridazine compound and use thereof |
| UA99466C2 (en) | 2007-07-06 | 2012-08-27 | Гилиад Сайенсиз, Инк. | Crystalline pyridazine compound |
| JP2011526881A (ja) * | 2008-06-25 | 2011-10-20 | ファイザー・インク | ジアリール化合物およびそれらの使用 |
| WO2009158309A2 (en) * | 2008-06-25 | 2009-12-30 | Ligand Pharmaceuticals Inc. | Biphenyl sulfonamides as dual angiotensin endothelin receptor antagonists |
| JP5528339B2 (ja) | 2008-07-08 | 2014-06-25 | 株式会社カネカ | α−ヘテロ置換アルキルハロヒドロシランの製造方法およびその利用 |
| CZ306650B6 (cs) * | 2011-03-04 | 2017-04-19 | Zentiva, K.S. | Způsob výroby 2-ethoxy-1-((2´-((hydroxyamino)iminomethyl)bifenyl-4-yl)methyl)-1H-benzo[d]imidazol-7-karboxylové kyseliny a jejích esterů, klíčových intermediátů syntézy azilsartanu |
| US9617246B2 (en) | 2013-12-18 | 2017-04-11 | Merck Sharp & Dohme Corp. | Thioether-piperidinyl orexin receptor antagonists |
| CN105669495A (zh) * | 2014-11-21 | 2016-06-15 | 重庆朗天制药有限公司 | 一种阿奇沙坦及其中间体新的制备方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4880804A (en) * | 1988-01-07 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking benzimidazoles |
| IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
| US5332744A (en) * | 1989-05-30 | 1994-07-26 | Merck & Co., Inc. | Substituted imidazo-fused 6-membered heterocycles as angiotensin II antagonists |
| US5223499A (en) * | 1989-05-30 | 1993-06-29 | Merck & Co., Inc. | 6-amino substituted imidazo[4,5-bipyridines as angiotensin II antagonists |
| EP0430709A3 (en) * | 1989-12-01 | 1992-02-12 | Glaxo Group Limited | Benzthiophen derivatives |
| DE4110019C2 (de) * | 1991-03-27 | 2000-04-13 | Merck Patent Gmbh | Imidazopyridine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
| IL102183A (en) * | 1991-06-27 | 1999-11-30 | Takeda Chemical Industries Ltd | Biphenyl substituted heterocyclic compounds their production and pharmaceutical compositions comprising them |
| DE4141788A1 (de) * | 1991-12-18 | 1993-06-24 | Merck Patent Gmbh | Imidazopyridine |
| DE4305602A1 (de) * | 1992-06-17 | 1993-12-23 | Merck Patent Gmbh | Imidazopyridine |
-
1993
- 1993-06-07 DE DE4318813A patent/DE4318813A1/de not_active Withdrawn
-
1994
- 1994-05-30 EP EP94108296A patent/EP0628556A1/de not_active Withdrawn
- 1994-06-01 AU AU63487/94A patent/AU689468B2/en not_active Expired - Fee Related
- 1994-06-03 CA CA002125077A patent/CA2125077A1/en not_active Abandoned
- 1994-06-03 SK SK677-94A patent/SK67794A3/sk unknown
- 1994-06-03 TW TW083105084A patent/TW269689B/zh active
- 1994-06-04 KR KR1019940012630A patent/KR950000697A/ko not_active Withdrawn
- 1994-06-04 CN CN94106500A patent/CN1100721A/zh active Pending
- 1994-06-06 CZ CZ941376A patent/CZ137694A3/cs unknown
- 1994-06-06 US US08/254,834 patent/US5438063A/en not_active Expired - Fee Related
- 1994-06-06 HU HU9401692A patent/HUT71483A/hu unknown
- 1994-06-06 RU RU94019981/04A patent/RU94019981A/ru unknown
- 1994-06-06 NO NO942095A patent/NO942095L/no unknown
- 1994-06-06 PL PL94303715A patent/PL303715A1/xx unknown
- 1994-06-07 ZA ZA943996A patent/ZA943996B/xx unknown
- 1994-06-07 JP JP6125330A patent/JPH072854A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH072854A (ja) | 1995-01-06 |
| SK67794A3 (en) | 1995-02-08 |
| NO942095D0 (no) | 1994-06-06 |
| AU6348794A (en) | 1994-12-08 |
| KR950000697A (ko) | 1995-01-03 |
| CZ137694A3 (en) | 1994-12-15 |
| RU94019981A (ru) | 1996-06-10 |
| CA2125077A1 (en) | 1994-12-08 |
| PL303715A1 (en) | 1995-01-09 |
| AU689468B2 (en) | 1998-04-02 |
| DE4318813A1 (de) | 1994-12-08 |
| EP0628556A1 (de) | 1994-12-14 |
| US5438063A (en) | 1995-08-01 |
| CN1100721A (zh) | 1995-03-29 |
| HUT71483A (en) | 1995-11-28 |
| TW269689B (fa) | 1996-02-01 |
| ZA943996B (en) | 1995-02-06 |
| HU9401692D0 (en) | 1994-09-28 |
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