NO940598L - - Google Patents
Info
- Publication number
- NO940598L NO940598L NO940598A NO940598A NO940598L NO 940598 L NO940598 L NO 940598L NO 940598 A NO940598 A NO 940598A NO 940598 A NO940598 A NO 940598A NO 940598 L NO940598 L NO 940598L
- Authority
- NO
- Norway
- Prior art keywords
- sphingoglycolipid
- integer
- chem
- isopropyl
- sec
- Prior art date
Links
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
- 241001251200 Agelas Species 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 229940034982 antineoplastic agent Drugs 0.000 abstract 1
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000091 immunopotentiator Effects 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000002914 sec-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Crystallography & Structural Chemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- External Artificial Organs (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3244384A JPH0559081A (ja) | 1991-08-29 | 1991-08-29 | 新規スフインゴ糖脂質、その製造法および使用 |
| PCT/JP1992/000561 WO1993005055A1 (fr) | 1991-08-29 | 1992-04-28 | Nouveau sphingoglycolipide et son utilisation |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| NO940598D0 NO940598D0 (no) | 1994-02-22 |
| NO940598L true NO940598L (de) | 1994-04-27 |
| NO180338B NO180338B (no) | 1996-12-23 |
| NO180338C NO180338C (no) | 1997-04-02 |
Family
ID=17117885
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940598A NO180338C (no) | 1991-08-29 | 1994-02-22 | Glycosfingolipider, fremgangsmåte til fremstilling av slike, antitumormiddel og immunostimulator |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0609437B1 (de) |
| JP (2) | JPH0559081A (de) |
| KR (1) | KR100220793B1 (de) |
| AT (1) | ATE181922T1 (de) |
| AU (1) | AU665536B2 (de) |
| CA (1) | CA2116442C (de) |
| DE (1) | DE69229557T2 (de) |
| DK (1) | DK0609437T3 (de) |
| ES (1) | ES2134213T3 (de) |
| FI (1) | FI105189B (de) |
| GR (1) | GR3030723T3 (de) |
| HU (1) | HU223839B1 (de) |
| NO (1) | NO180338C (de) |
| PT (1) | PT100736B (de) |
| SG (1) | SG44031A1 (de) |
| TW (1) | TW197446B (de) |
| WO (1) | WO1993005055A1 (de) |
| ZA (1) | ZA923239B (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5936076A (en) * | 1991-08-29 | 1999-08-10 | Kirin Beer Kabushiki Kaisha | αgalactosylceramide derivatives |
| TW261533B (de) * | 1992-07-16 | 1995-11-01 | Kirin Brewery | |
| AU683026B2 (en) * | 1992-10-22 | 1997-10-30 | Kirin Pharma Kabushiki Kaisha | Novel shingoglycolipid and use thereof |
| EP0694558B1 (de) * | 1993-04-15 | 1999-01-27 | Kirin Beer Kabushiki Kaisha | Sphingoglycolipid und verwendung davon |
| TW555562B (en) | 1996-12-27 | 2003-10-01 | Kirin Brewery | Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof |
| TW575420B (en) * | 1997-09-22 | 2004-02-11 | Kirin Brewery | Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides |
| AU782539B2 (en) * | 2000-01-14 | 2005-08-04 | Meiji Dairies Corporation | Antigen-specific IgE antibody production inhibitors |
| JP2002030093A (ja) * | 2000-03-13 | 2002-01-29 | Nof Corp | グリコシルセラミドの精製方法 |
| EP1437358B1 (de) | 2001-08-16 | 2006-10-18 | Daiichi Asubio Pharma Co., Ltd. | Neues glykolipid, und heilmittel für autoimmunerkrankungen, das dieses als wirkstoff enthält |
| BR0314640A (pt) * | 2002-09-20 | 2005-08-02 | Kirin Brewery | Inibidor de vìrus de hepatite c compreendendo, como um ingrediente ativo, alfa-glicosilceramida |
| JP4585172B2 (ja) * | 2003-01-31 | 2010-11-24 | 森永乳業株式会社 | 骨形成促進剤 |
| ES2676345T3 (es) | 2003-02-14 | 2018-07-18 | Japan As Represented By President Of National Center Of Neurology And Psychiatry Ministry Of Health | Derivados del glicolípido, proceso para su producción, intermedios para la síntesis del mismo, y proceso para la producción de los intermedios |
| JP4753089B2 (ja) * | 2004-12-20 | 2011-08-17 | 株式会社岡安商店 | 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤 |
| JP2007070311A (ja) * | 2005-09-09 | 2007-03-22 | Gunma Univ | α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤 |
| EP1776963A1 (de) | 2005-10-19 | 2007-04-25 | Gbf-Gesellschaft Für Biotechnologische Forschung Mbh | Hexosylceramiden als Adjuvantien und ihre Verwendung in pharmazeutischen Zusammensetzungen |
| WO2008047174A1 (en) * | 2006-10-18 | 2008-04-24 | Centre National De La Recherche Scientifique | Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them |
| KR100868959B1 (ko) * | 2006-12-30 | 2008-11-17 | 재단법인서울대학교산학협력재단 | 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물 |
| US7959907B2 (en) | 2007-02-21 | 2011-06-14 | Vib Vzw | Method of treating cancer by combination therapy using TNF and alpha-galactosylceramide |
| JP4995172B2 (ja) * | 2008-10-10 | 2012-08-08 | 壽製薬株式会社 | 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬 |
| JP5719783B2 (ja) | 2009-02-16 | 2015-05-20 | セレニス セラピューティクス ホールディング エスアー | アポリポタンパクａ−ｉ模倣物 |
| JP5095683B2 (ja) * | 2009-07-06 | 2012-12-12 | 壽製薬株式会社 | 新規糖脂質誘導体及びこれを有効成分とする製剤 |
| JP5025692B2 (ja) * | 2009-07-06 | 2012-09-12 | 壽製薬株式会社 | 糖脂質誘導体の製造方法 |
| JP2010254718A (ja) * | 2010-08-13 | 2010-11-11 | Morinaga Milk Ind Co Ltd | 骨形成促進剤 |
| SG189019A1 (en) | 2010-10-18 | 2013-05-31 | Cerenis Therapeutics Holding Sa | Compounds, compositions and methods useful for cholesterol mobilisation |
| WO2012074116A1 (ja) | 2010-12-02 | 2012-06-07 | 独立行政法人理化学研究所 | アロNKT細胞を用いた免疫療法およびそのためのT細胞抗原受容体（TCR）遺伝子のα鎖領域が均一なVα-Jαに再構成されている細胞および該細胞由来NKT細胞のバンキング |
| WO2014021464A1 (ja) * | 2012-08-03 | 2014-02-06 | 独立行政法人理化学研究所 | 水酸化ｋｒｎ７０００類縁体及びその用途 |
| WO2014053482A1 (en) | 2012-10-03 | 2014-04-10 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists |
| PL2923208T3 (pl) | 2012-11-21 | 2019-09-30 | Institut National De La Santé Et De La Recherche Médicale (Inserm) | Sposoby określania ryzyka ostrej choroby przeszczep przeciwko gospodarzowi |
| WO2017207040A1 (en) | 2016-06-01 | 2017-12-07 | Vib Vzw | ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR |
| KR102328367B1 (ko) * | 2019-11-05 | 2021-11-18 | 한국해양과학기술원 | 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물 |
| CN116528839A (zh) | 2020-12-04 | 2023-08-01 | 瑞格国际生技股份有限公司 | 药代动力学被改善的含CD1d配体化合物的脂质体制剂 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6157594A (ja) * | 1984-08-30 | 1986-03-24 | Suntory Ltd | ガラクトスフインゴ脂質及びその製造法 |
| JP2588729B2 (ja) * | 1987-10-05 | 1997-03-12 | 塩野義製薬株式会社 | スフィンゴシン誘導体 |
| DE3840044A1 (de) * | 1988-11-27 | 1990-06-07 | Behringwerke Ag | Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung |
| JP3068910B2 (ja) * | 1990-11-08 | 2000-07-24 | 麒麟麦酒株式会社 | 新規スフィンゴ糖脂質、その製造法および使用 |
-
1991
- 1991-08-29 JP JP3244384A patent/JPH0559081A/ja active Pending
-
1992
- 1992-04-28 EP EP92909489A patent/EP0609437B1/de not_active Expired - Lifetime
- 1992-04-28 DK DK92909489T patent/DK0609437T3/da active
- 1992-04-28 ES ES92909489T patent/ES2134213T3/es not_active Expired - Lifetime
- 1992-04-28 SG SG1996009529A patent/SG44031A1/en unknown
- 1992-04-28 AT AT92909489T patent/ATE181922T1/de active
- 1992-04-28 DE DE69229557T patent/DE69229557T2/de not_active Expired - Lifetime
- 1992-04-28 AU AU16664/92A patent/AU665536B2/en not_active Expired
- 1992-04-28 WO PCT/JP1992/000561 patent/WO1993005055A1/ja not_active Ceased
- 1992-04-28 JP JP4508706A patent/JP2774194B2/ja not_active Expired - Lifetime
- 1992-04-28 HU HU9400596A patent/HU223839B1/hu active IP Right Grant
- 1992-04-28 CA CA002116442A patent/CA2116442C/en not_active Expired - Lifetime
- 1992-04-28 KR KR1019940700662A patent/KR100220793B1/ko not_active Expired - Fee Related
- 1992-05-05 ZA ZA923239A patent/ZA923239B/xx unknown
- 1992-05-06 TW TW081103536A patent/TW197446B/zh not_active IP Right Cessation
- 1992-07-28 PT PT100736A patent/PT100736B/pt not_active IP Right Cessation
-
1994
- 1994-02-22 NO NO940598A patent/NO180338C/no not_active IP Right Cessation
- 1994-02-23 FI FI940851A patent/FI105189B/fi not_active IP Right Cessation
-
1999
- 1999-07-08 GR GR990400800T patent/GR3030723T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU665536B2 (en) | 1996-01-11 |
| CA2116442A1 (en) | 1993-03-18 |
| HK1009967A1 (en) | 1999-09-17 |
| HU9400596D0 (en) | 1994-05-30 |
| CA2116442C (en) | 2000-09-05 |
| DK0609437T3 (da) | 2000-01-31 |
| EP0609437A4 (en) | 1994-08-24 |
| DE69229557D1 (de) | 1999-08-12 |
| ZA923239B (en) | 1993-05-05 |
| EP0609437A1 (de) | 1994-08-10 |
| EP0609437B1 (de) | 1999-07-07 |
| JP2774194B2 (ja) | 1998-07-09 |
| NO180338C (no) | 1997-04-02 |
| AU1666492A (en) | 1993-04-05 |
| NO180338B (no) | 1996-12-23 |
| HUT70435A (en) | 1995-10-30 |
| GR3030723T3 (en) | 1999-11-30 |
| TW197446B (de) | 1993-01-01 |
| JPH0559081A (ja) | 1993-03-09 |
| DE69229557T2 (de) | 1999-11-25 |
| WO1993005055A1 (fr) | 1993-03-18 |
| HU223839B1 (hu) | 2005-02-28 |
| FI940851A7 (fi) | 1994-02-23 |
| ES2134213T3 (es) | 1999-10-01 |
| FI105189B (fi) | 2000-06-30 |
| FI940851A0 (fi) | 1994-02-23 |
| PT100736B (pt) | 1999-04-30 |
| NO940598D0 (no) | 1994-02-22 |
| KR100220793B1 (ko) | 1999-10-01 |
| SG44031A1 (en) | 1997-11-14 |
| ATE181922T1 (de) | 1999-07-15 |
| PT100736A (pt) | 1993-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |