TW197446B - - Google Patents

Info

Publication number
TW197446B
TW197446B TW081103536A TW81103536A TW197446B TW 197446 B TW197446 B TW 197446B TW 081103536 A TW081103536 A TW 081103536A TW 81103536 A TW81103536 A TW 81103536A TW 197446 B TW197446 B TW 197446B
Authority
TW
Taiwan
Prior art keywords
sphingoglycolipid
integer
chem
isopropyl
sec
Prior art date
Application number
TW081103536A
Other languages
English (en)
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Application granted granted Critical
Publication of TW197446B publication Critical patent/TW197446B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
TW081103536A 1991-08-29 1992-05-06 TW197446B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3244384A JPH0559081A (ja) 1991-08-29 1991-08-29 新規スフインゴ糖脂質、その製造法および使用

Publications (1)

Publication Number Publication Date
TW197446B true TW197446B (zh) 1993-01-01

Family

ID=17117885

Family Applications (1)

Application Number Title Priority Date Filing Date
TW081103536A TW197446B (zh) 1991-08-29 1992-05-06

Country Status (19)

Country Link
EP (1) EP0609437B1 (zh)
JP (2) JPH0559081A (zh)
KR (1) KR100220793B1 (zh)
AT (1) ATE181922T1 (zh)
AU (1) AU665536B2 (zh)
CA (1) CA2116442C (zh)
DE (1) DE69229557T2 (zh)
DK (1) DK0609437T3 (zh)
ES (1) ES2134213T3 (zh)
FI (1) FI105189B (zh)
GR (1) GR3030723T3 (zh)
HK (1) HK1009967A1 (zh)
HU (1) HU223839B1 (zh)
NO (1) NO180338C (zh)
PT (1) PT100736B (zh)
SG (1) SG44031A1 (zh)
TW (1) TW197446B (zh)
WO (1) WO1993005055A1 (zh)
ZA (1) ZA923239B (zh)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5936076A (en) * 1991-08-29 1999-08-10 Kirin Beer Kabushiki Kaisha αgalactosylceramide derivatives
TW261533B (zh) * 1992-07-16 1995-11-01 Kirin Brewery
US5849716A (en) * 1992-10-22 1998-12-15 Kirin Beer Kabushiki Kaisha Sphingoglycolipids, their preparation, and therapeutic methods of use
DE69416306T2 (de) * 1993-04-15 1999-06-17 Kirin Brewery Sphingoglycolipid und verwendung davon
TW555562B (en) * 1996-12-27 2003-10-01 Kirin Brewery Method for activation of human antigen-presenting cells, activated human antigen-presenting cells and use thereof
TW575420B (en) * 1997-09-22 2004-02-11 Kirin Brewery Composition for enhancing cellular immunogenicity comprising alpha-glycosylceramides
CN100384472C (zh) * 2000-01-14 2008-04-30 明治乳业株式会社 抗原特异性IgE抗体产生抑制剂
JP2002030093A (ja) * 2000-03-13 2002-01-29 Nof Corp グリコシルセラミドの精製方法
ATE342910T1 (de) * 2001-08-16 2006-11-15 Daiichi Asubio Pharma Co Ltd Neues glykolipid, und heilmittel für autoimmunerkrankungen, das dieses als wirkstoff enthält
WO2004026318A1 (ja) * 2002-09-20 2004-04-01 Kirin Beer Kabushiki Kaisha α-グリコシルセラミドを有効成分とするＣ型肝炎ウイルス抑制剤
JP4585172B2 (ja) * 2003-01-31 2010-11-24 森永乳業株式会社 骨形成促進剤
BRPI0407501A (pt) * 2003-02-14 2006-02-14 Daiichi Suntory Pharma Co Ltd glicolipìdeos e método sintético dos mesmos bem como seus intermediários sintéticos, e método sintético dos mesmos
WO2006068041A1 (ja) * 2004-12-20 2006-06-29 Okayasu Shoten Co., Ltd. 体内脂肪の分解促進作用を有する組成物及びそれを含有する食品又は食品配合剤
JP2007070311A (ja) * 2005-09-09 2007-03-22 Gunma Univ α−ガラクトシルセラミドからなる感染症予防剤及び感染症治療剤
EP1776963A1 (en) 2005-10-19 2007-04-25 Gbf-Gesellschaft Für Biotechnologische Forschung Mbh Hexosylceramides as adjuvants and their uses in pharmaceutical compositions
WO2008047174A1 (en) * 2006-10-18 2008-04-24 Centre National De La Recherche Scientifique Alpha-galactosylceramide analogs, their methods of manufacture, intermediate compounds useful in these methods, and pharmaceutical compositions containing them
KR100868959B1 (ko) * 2006-12-30 2008-11-17 재단법인서울대학교산학협력재단 알파-갈락토실세라마이드 유도체, 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 함유하는면역보조용 약학적 조성물
CA2678088A1 (en) 2007-02-21 2008-08-28 Universiteit Gent Combination therapy using tnf and alfa-galactosyl ceramide
JP4995172B2 (ja) * 2008-10-10 2012-08-08 壽製薬株式会社 糖脂質誘導体、その製造方法並びにそれを有効成分とする医薬
PT2939683T (pt) 2009-02-16 2017-04-07 Cerenis Therapeutics Holding Sa Miméticos da apolipoproteína a-i
JP5025692B2 (ja) * 2009-07-06 2012-09-12 壽製薬株式会社 糖脂質誘導体の製造方法
JP5095683B2 (ja) * 2009-07-06 2012-12-12 壽製薬株式会社 新規糖脂質誘導体及びこれを有効成分とする製剤
JP2010254718A (ja) * 2010-08-13 2010-11-11 Morinaga Milk Ind Co Ltd 骨形成促進剤
KR20180014188A (ko) 2010-10-18 2018-02-07 세레니스 쎄라퓨틱스 홀딩 에스에이 콜레스테롤 이동에 유용한 화합물, 조성물 및 방법
JPWO2012074116A1 (ja) 2010-12-02 2014-05-19 独立行政法人理化学研究所 アロＮＫＴ細胞を用いた免疫療法およびそのためのＴ細胞抗原受容体（ＴＣＲ）遺伝子のα鎖領域が均一なＶα−Ｊαに再構成されている細胞および該細胞由来ＮＫＴ細胞のバンキング
US9464105B2 (en) 2012-08-03 2016-10-11 Riken Hydroxylated KRN7000 analogue and use thereof
WO2014053482A1 (en) 2012-10-03 2014-04-10 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and pharmaceutical compositions for the prophylactic treatment of bacterial superinfections post-influenza with invariant nkt cell agonists
PL2923208T3 (pl) 2012-11-21 2019-09-30 Institut National De La Santé Et De La Recherche Médicale (Inserm) Sposoby określania ryzyka ostrej choroby przeszczep przeciwko gospodarzowi
WO2017207040A1 (en) 2016-06-01 2017-12-07 Vib Vzw ANTI-CANCER THERAPY USING A LEPTIN ANTAGONIST AND AN iNKT-CELL ACTIVATOR
KR102328367B1 (ko) * 2019-11-05 2021-11-18 한국해양과학기술원 아젤록심 d를 유효성분으로 함유하는 방사선 민감성 증진용 조성물
IL303285A (en) 2020-12-04 2023-07-01 Regimmune Corp A liposome preparation containing a ligand-CD1D compound with improved pharmacokinetics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6157594A (ja) * 1984-08-30 1986-03-24 Suntory Ltd ガラクトスフインゴ脂質及びその製造法
JP2588729B2 (ja) * 1987-10-05 1997-03-12 塩野義製薬株式会社 スフィンゴシン誘導体
DE3840044A1 (de) * 1988-11-27 1990-06-07 Behringwerke Ag Glykosphingolipide mit kopplungsfaehiger gruppe im sphingoidanteil, ihre herstellung und verwendung

Also Published As

Publication number Publication date
KR100220793B1 (ko) 1999-10-01
WO1993005055A1 (en) 1993-03-18
NO180338C (no) 1997-04-02
ATE181922T1 (de) 1999-07-15
PT100736B (pt) 1999-04-30
EP0609437B1 (en) 1999-07-07
FI940851A0 (fi) 1994-02-23
ZA923239B (en) 1993-05-05
HU223839B1 (hu) 2005-02-28
DE69229557D1 (de) 1999-08-12
AU665536B2 (en) 1996-01-11
CA2116442A1 (en) 1993-03-18
HU9400596D0 (en) 1994-05-30
JPH0559081A (ja) 1993-03-09
PT100736A (pt) 1993-09-30
EP0609437A1 (en) 1994-08-10
HK1009967A1 (en) 1999-09-17
NO180338B (no) 1996-12-23
EP0609437A4 (en) 1994-08-24
NO940598D0 (no) 1994-02-22
CA2116442C (en) 2000-09-05
FI940851A (fi) 1994-02-23
FI105189B (fi) 2000-06-30
JP2774194B2 (ja) 1998-07-09
ES2134213T3 (es) 1999-10-01
HUT70435A (en) 1995-10-30
SG44031A1 (en) 1997-11-14
DE69229557T2 (de) 1999-11-25
GR3030723T3 (en) 1999-11-30
DK0609437T3 (da) 2000-01-31
NO940598L (zh) 1994-04-27
AU1666492A (en) 1993-04-05

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Legal Events

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