NO934196L - N,N-disubstituerte arylcykloalkylaminer, deres salter, legemidler inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for deres fremstilling - Google Patents
N,N-disubstituerte arylcykloalkylaminer, deres salter, legemidler inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for deres fremstillingInfo
- Publication number
- NO934196L NO934196L NO934196A NO934196A NO934196L NO 934196 L NO934196 L NO 934196L NO 934196 A NO934196 A NO 934196A NO 934196 A NO934196 A NO 934196A NO 934196 L NO934196 L NO 934196L
- Authority
- NO
- Norway
- Prior art keywords
- salts
- compounds
- preparation
- drugs containing
- arylcycloalkylamines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/20—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/57—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
- C07C233/62—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/79—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
- C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/07—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
Abstract
Oppfinnelsen angår N,N-disubstituerte arylcykloalkylaminer med den generelle formel hvor n, m, A, X og R1 til R7 er som definert i krav l, deres isomerer, isomerblandinger og deres salter, som oppviser verdifulle egenskaper, spesielt utøver en inhiberende virkning på kolesterolbiosyntesen.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4239151A DE4239151A1 (de) | 1992-11-20 | 1992-11-20 | N,N-Disubstituierte Arylcycloalkylamine, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
NO934196D0 NO934196D0 (no) | 1993-11-19 |
NO934196L true NO934196L (no) | 1994-05-24 |
Family
ID=6473324
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO934196A NO934196L (no) | 1992-11-20 | 1993-11-19 | N,N-disubstituerte arylcykloalkylaminer, deres salter, legemidler inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for deres fremstilling |
Country Status (19)
Country | Link |
---|---|
US (1) | US5455273A (no) |
EP (1) | EP0599203A1 (no) |
JP (1) | JPH06211763A (no) |
KR (1) | KR940011435A (no) |
CN (1) | CN1093082A (no) |
AU (1) | AU665281B2 (no) |
CA (1) | CA2103381A1 (no) |
CZ (1) | CZ248593A3 (no) |
DE (1) | DE4239151A1 (no) |
FI (1) | FI935110A (no) |
HU (1) | HU211996B (no) |
IL (1) | IL107653A0 (no) |
MX (1) | MX9307232A (no) |
NO (1) | NO934196L (no) |
NZ (1) | NZ250230A (no) |
PL (1) | PL301101A1 (no) |
SK (1) | SK123993A3 (no) |
TW (1) | TW252097B (no) |
ZA (1) | ZA938647B (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4239150A1 (de) * | 1992-11-20 | 1994-05-26 | Thomae Gmbh Dr K | O-Acyl-4-phenyl-cyclohexanole, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
US5962507A (en) * | 1994-04-25 | 1999-10-05 | Dr. Karl Thomae Gmbh | O-acyl-4-phenyl-cyclohexanols, their salts, medicaments containing such compounds, and their use, as well as a method of preparing them |
IL110943A (en) * | 1994-09-13 | 1997-02-18 | Univ Ramot | Compositions comprising an inhibitor of cholesterol synthesis for the treatment of skin disorders |
EP0738510A3 (fr) * | 1995-04-20 | 2005-12-21 | L'oreal | Utilisation d'un inhibiteur d'HMG-coenzyme A-reductase pour lutter contre le vieillissement de la peau et pour traiter l'acné. Composition comprenant au moins un inhibiteur HMG-coenzyme A reductase et au moins un actif possédant des propriétes desquamantes |
EP2201944B1 (en) | 1997-11-21 | 2012-05-23 | Purdue Neuroscience Company | Use of substituted 2-aminoacetamides for treating, preventing or ameliorating manic depression |
DE19754795A1 (de) * | 1997-12-10 | 1999-06-17 | Boehringer Ingelheim Pharma | Neue Urethane, ihre Thio- und Dithioanaloga, deren Salze, diese Verbindungen enthaltende Arzneimittel und deren Verwendung sowie Verfahren zu ihrer Herstellung |
US6410521B1 (en) * | 1998-06-12 | 2002-06-25 | Osteoscreen, Inc. | Nutritional supplements for stimulating bone growth |
JP2003535851A (ja) | 2000-06-06 | 2003-12-02 | ワーナー−ランバート・カンパニー、リミテッド、ライアビリティ、カンパニー | 二環式シクロヘキシルアミン類およびそれらのnmda受容体アンタゴニストとしての使用 |
RU2225393C1 (ru) * | 2000-08-16 | 2004-03-10 | Ф.Хоффманн-Ля Рош Аг | Новые производные аминоциклогексана |
ES2276974T3 (es) * | 2001-12-12 | 2007-07-01 | F. Hoffmann-La Roche Ag | Derivados de ciclohexano sustituidos. |
US7012077B2 (en) | 2001-12-20 | 2006-03-14 | Hoffmann-La Roche Inc. | Substituted cyclohexane derivatives |
WO2004026259A2 (en) * | 2002-09-20 | 2004-04-01 | Griscom Bettle, Iii | Transdermal compositions |
TW200808695A (en) * | 2006-06-08 | 2008-02-16 | Amgen Inc | Benzamide derivatives and uses related thereto |
KR101420730B1 (ko) | 2007-10-31 | 2014-07-18 | 삼성전자주식회사 | 영상기기 및 그의 영상신호 수신방법 |
JP5453165B2 (ja) * | 2010-05-13 | 2014-03-26 | 信越化学工業株式会社 | アルデヒド及びケトンの製造方法 |
RU2016149812A (ru) | 2014-06-06 | 2018-07-17 | Флексус Байосайенсиз, Инк. | Иммунорегулирующие средства |
WO2016073738A2 (en) | 2014-11-05 | 2016-05-12 | Flexus Biosciences, Inc. | Immunoregulatory agents |
UY36390A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
AR102537A1 (es) | 2014-11-05 | 2017-03-08 | Flexus Biosciences Inc | Agentes inmunomoduladores |
JP2019516681A (ja) * | 2016-05-04 | 2019-06-20 | ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company | インドールアミン2,3−ジオキシゲナーゼ阻害剤およびその使用方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3979444A (en) * | 1974-05-28 | 1976-09-07 | The Upjohn Company | 4-Arylcyclohexylamines |
US4886929A (en) * | 1987-06-15 | 1989-12-12 | Uop Inc. | Separation of para-xylene |
CA2044533A1 (en) * | 1990-06-29 | 1991-12-30 | Philippe Guerry | Substituted aminoalkylbiphenyl derivatives |
-
1992
- 1992-11-20 DE DE4239151A patent/DE4239151A1/de not_active Withdrawn
-
1993
- 1993-10-19 TW TW082108692A patent/TW252097B/zh active
- 1993-11-05 SK SK1239-93A patent/SK123993A3/sk unknown
- 1993-11-18 NZ NZ250230A patent/NZ250230A/en unknown
- 1993-11-18 FI FI935110A patent/FI935110A/fi not_active Application Discontinuation
- 1993-11-18 CA CA002103381A patent/CA2103381A1/en not_active Abandoned
- 1993-11-18 EP EP93118595A patent/EP0599203A1/de not_active Ceased
- 1993-11-18 IL IL10765393A patent/IL107653A0/xx unknown
- 1993-11-19 NO NO934196A patent/NO934196L/no unknown
- 1993-11-19 KR KR1019930024711A patent/KR940011435A/ko not_active Application Discontinuation
- 1993-11-19 JP JP5290687A patent/JPH06211763A/ja active Pending
- 1993-11-19 PL PL93301101A patent/PL301101A1/xx unknown
- 1993-11-19 AU AU51825/93A patent/AU665281B2/en not_active Expired - Fee Related
- 1993-11-19 CZ CZ932485A patent/CZ248593A3/cs unknown
- 1993-11-19 MX MX9307232A patent/MX9307232A/es unknown
- 1993-11-19 CN CN93114684A patent/CN1093082A/zh active Pending
- 1993-11-19 HU HU9303298A patent/HU211996B/hu not_active IP Right Cessation
- 1993-11-19 US US08/154,644 patent/US5455273A/en not_active Expired - Fee Related
- 1993-11-19 ZA ZA938647A patent/ZA938647B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
SK123993A3 (en) | 1994-09-07 |
CA2103381A1 (en) | 1994-05-21 |
TW252097B (no) | 1995-07-21 |
US5455273A (en) | 1995-10-03 |
EP0599203A1 (de) | 1994-06-01 |
HU211996B (en) | 1996-01-29 |
FI935110A (fi) | 1994-05-21 |
ZA938647B (en) | 1995-05-19 |
DE4239151A1 (de) | 1994-05-26 |
HUT65760A (en) | 1994-07-28 |
PL301101A1 (en) | 1994-06-27 |
AU5182593A (en) | 1994-06-02 |
FI935110A0 (fi) | 1993-11-18 |
JPH06211763A (ja) | 1994-08-02 |
AU665281B2 (en) | 1995-12-21 |
NO934196D0 (no) | 1993-11-19 |
MX9307232A (es) | 1994-07-29 |
KR940011435A (ko) | 1994-06-21 |
HU9303298D0 (en) | 1994-03-28 |
CZ248593A3 (en) | 1994-06-15 |
NZ250230A (en) | 1996-02-27 |
CN1093082A (zh) | 1994-10-05 |
IL107653A0 (en) | 1994-02-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO934196L (no) | N,N-disubstituerte arylcykloalkylaminer, deres salter, legemidler inneholdende disse forbindelser, deres anvendelse og fremgangsmåte for deres fremstilling | |
MY107740A (en) | Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof | |
DK0741694T3 (da) | Phenyleddikesyrederivater, fremgangsmåder og mellemprodukter til deres fremstilling og midler indeholdende disse | |
MX9707453A (es) | Derivados de quinazolina. | |
MY119150A (en) | Azetidine derivatives, their preparation and medicaments containing them | |
SE9904505D0 (sv) | Novel compounds | |
NO20022558L (no) | 4-karboksyamino-2-etyl-1,2,3,4-tetrahydrokinolinkrystall som CETP inhibitor | |
DK0506539T3 (da) | heterocykliske alkylamider, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
ATE211732T1 (de) | N-benzylpiperidin- und tetrahydropyridin-derivate | |
DK0759919T3 (da) | Azolidindioner som antihyperglykæmiske midler | |
ES2098947T3 (es) | Derivados de beta,beta-dimetil-4-piperidinoetanamina como inhibidores de la biosintesis del colesterol. | |
DK0649846T3 (da) | Galanthaminderivater, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler | |
NO20000957L (no) | Forgrenede alkoksy-substituerte 2-aminopyridiner som NOS inhibitorer | |
MX9803730A (es) | Nuevo proceso de preparacion de derivados de fenilimidazolidina. | |
NO981393L (no) | Guanidinoproteasehemmere | |
DK0526313T3 (da) | Nye ureaderivater, deres fremstilling og terapeutiske anvendelse | |
YU44202A (sh) | Kvaternerne soli n-substituisanih cikiličnih ili ne- cikličnih amina kao farmaceutski preparati | |
DK0632026T3 (da) | Alfa-aminosyrederivater, en fremgangsmåde til deres fremstilling og farmaceutiske sammensætninger, der indeholder dem | |
ES2152563T3 (es) | Procedimiento para preparar derivados de dihidroxipirimidina. | |
DK0452204T3 (da) | Hidtil ukendte 3-aminochromanderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
NO982072L (no) | Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase | |
EA200000389A3 (ru) | Новые замещенные пиридины или пиперидины, способ их получения и содержащие их фармацевтические композиции | |
NO964525D0 (no) | O-Acyl-4-fenyl-cykloheksanoler, deres salter, legemidler som inneholder disse forbindelser og deres anvendelse, samt fremgangsmåter for fremstilling av dem | |
DK0535192T3 (da) | Hidtil ukendte DNA-gyraseinhibitorer, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende dem | |
DK1000067T3 (da) | Thiazolobenzoheterocycliske forbindelser, deres fremstilling og lægemidler indeholdende forbindelserne |