DK0526313T3 - Nye ureaderivater, deres fremstilling og terapeutiske anvendelse - Google Patents

Nye ureaderivater, deres fremstilling og terapeutiske anvendelse

Info

Publication number
DK0526313T3
DK0526313T3 DK92402131.4T DK92402131T DK0526313T3 DK 0526313 T3 DK0526313 T3 DK 0526313T3 DK 92402131 T DK92402131 T DK 92402131T DK 0526313 T3 DK0526313 T3 DK 0526313T3
Authority
DK
Denmark
Prior art keywords
group
urea derivatives
preparation
radical
new urea
Prior art date
Application number
DK92402131.4T
Other languages
English (en)
Inventor
Dennis Bigg
Jean-Louis Vidaluc
Original Assignee
Pierre Fabre M Dicament
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre M Dicament filed Critical Pierre Fabre M Dicament
Application granted granted Critical
Publication of DK0526313T3 publication Critical patent/DK0526313T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
    • C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
    • C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
    • C07C275/48—Y being a hydrogen or a carbon atom
    • C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/04—Derivatives of thiourea
    • C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C335/18—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK92402131.4T 1991-07-25 1992-07-23 Nye ureaderivater, deres fremstilling og terapeutiske anvendelse DK0526313T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9109446A FR2679555B1 (fr) 1991-07-25 1991-07-25 Nouveaux derives de l'uree, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
DK0526313T3 true DK0526313T3 (da) 1995-08-21

Family

ID=9415541

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92402131.4T DK0526313T3 (da) 1991-07-25 1992-07-23 Nye ureaderivater, deres fremstilling og terapeutiske anvendelse

Country Status (8)

Country Link
US (1) US5288758A (da)
EP (1) EP0526313B1 (da)
JP (1) JPH05194359A (da)
AT (1) ATE121385T1 (da)
DE (1) DE69202120T2 (da)
DK (1) DK0526313T3 (da)
ES (1) ES2073258T3 (da)
FR (1) FR2679555B1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9206989D0 (en) * 1992-03-31 1992-05-13 Glaxo Group Ltd Chemical compounds
ES2141763T3 (es) * 1992-03-31 2000-04-01 Glaxo Group Ltd Fenilcarbonatos y fenilureas sustituidos, su preparacion y su uso como antagonistas de 5-ht4.
KR970703301A (ko) * 1994-05-18 1997-07-03 쇼오다 오사무 신규 디아미노메틸리덴 유도체(novel diamincmethylidene derivative)
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
CN1163224C (zh) 1998-09-30 2004-08-25 武田药品工业株式会社 改善膀胱排泄能力的药物
JPWO2005080322A1 (ja) * 2004-02-20 2007-10-25 アステラス製薬株式会社 フルオレン誘導体
JPWO2005079845A1 (ja) * 2004-02-20 2007-08-02 アステラス製薬株式会社 片頭痛予防薬
EP1852129A4 (en) * 2005-02-08 2009-07-15 Astellas Pharma Inc REMEDIES FOR IRRITATION SYNDROME
EP1923387B1 (en) * 2005-08-08 2011-10-19 Astellas Pharma Inc. Acylguanidine derivative or salt thereof
PE20070797A1 (es) 2005-11-25 2007-09-27 Basf Ag Compuestos de indanil- y tetrahidronaftil-amino-tiourea para combatir pestes animales
WO2011100373A1 (en) * 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
AU2016268096B2 (en) 2015-05-22 2021-04-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3061640A (en) * 1959-03-30 1962-10-30 Monsanto Chemicals 3, 4-dichlorophenyl dialkylaminoalkyl ureas and thioureas
US3049562A (en) * 1961-03-09 1962-08-14 American Cyanamid Co 1-(aralkyl, lower alkylamino lower alkyl), 1-phenyl, 3, 3-dilower alkylureas
US3903154A (en) * 1973-08-03 1975-09-02 Chevron Res Herbicidal substituted-haloethyl urea
JPH0140026B2 (da) * 1978-07-03 1989-08-24 Amerikan Hoomu Purodakutsu Corp
US4474707A (en) * 1980-10-09 1984-10-02 American Home Products Corporation N-3-Propenylaminopropyl-N'-phenylureas
US4297373A (en) * 1980-10-09 1981-10-27 American Home Products Corporation Method of suppressing cardiac arrhythmias
US5015644A (en) * 1987-06-02 1991-05-14 Warner-Lambert Company Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds
US5116848A (en) * 1988-03-30 1992-05-26 Warner-Lambert Company N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents
US5106873A (en) * 1990-06-26 1992-04-21 Warner-Lambert Company ACAT inhibitors

Also Published As

Publication number Publication date
JPH05194359A (ja) 1993-08-03
ES2073258T3 (es) 1995-08-01
ATE121385T1 (de) 1995-05-15
DE69202120T2 (de) 1995-11-30
EP0526313A1 (fr) 1993-02-03
EP0526313B1 (fr) 1995-04-19
FR2679555B1 (fr) 1993-11-19
US5288758A (en) 1994-02-22
DE69202120D1 (de) 1995-05-24
FR2679555A1 (fr) 1993-01-29

Similar Documents

Publication Publication Date Title
FR2508035B1 (da)
DK0526313T3 (da) Nye ureaderivater, deres fremstilling og terapeutiske anvendelse
NO20045369L (no) Nye, substituerte sulfamatanticonvulsivaderivater
DK0958296T3 (da) Heterocykliske forbindelser, fremgangsmåde til deres fremstilling og farmaceutiske præparater, der indeholder dem, og deres anvendelse i behandlingen af diabetes og beslægtede sygdomme
NO953305L (no) Antranilsyrederivat
DK256890A (da) Benzo-piperidin-, -piperidyliden- og piperazinforbindelser, kompositioner indeholdende forbindelserne og fremgangsmaader til forbindelsernes fremstilling og anvendelse
NO990433L (no) Nye forbindelser og blandinger for behandling av sykdommer i forbindelse med tryptase-aktivitet
ES2132284T3 (es) Derivados de carbamato de 2-(piperidin-4-il, piridin-4-il y tetrahidropiridin-4-il)-benzofurano-7, su preparacion y su uso como inhibidores de acetilcolinesterasa.
DE68917485D1 (de) Pyridazinon-Derivate und diese enthaltende pharmazeutische Zubereitungen.
BR0006333A (pt) Compostos heteroaril-fenil-pirazol como agentesantiinflamatórios e analgésicos
MX9806171A (es) Derivados 2,3-benzodiazepina y sus usos como inhibidores del receptor-ampa.
DK492288D0 (da) Amidforbindelser, farmaceutisk praeparat indeholdende samme samt fremgangsmaade til fremstilling af forbindelserne
DK1000067T3 (da) Thiazolobenzoheterocycliske forbindelser, deres fremstilling og lægemidler indeholdende forbindelserne
NO923983D0 (no) Bisfenyletanderivater, fremgangsmaate for deres fremstilling og deres terapeutiske anvendelse
NO913543D0 (no) Fremgangsmaate for fremstilling av 3-(1h-indazol-3-yl)-4-pyridinaminer og mellomprodukter, og anvendelse som medikamenter.
DK360388A (da) Laegemiddel til behandling af hjerteinsufficiens
NO893039D0 (no) Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler.
NO961719D0 (no) 3-aryl-4-alkyl og 4,5-dialkyl-4H-1,2,4-triazoler som er anvendbare som hukommelsesforsterkere
DK0784973T3 (da) Quinoxalinderivater til behandling af tinnitus
GR3022450T3 (en) Piperidine derivatives with antihistaminic and antileukohienic activity.
NO932002L (no) Nye tiosemikarbazonsyreestere
NO954764L (no) Psoralen-derivater, deres fremstilling og anvendelse
DK0587048T3 (da) Heteroarenylpiperaziner, en fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
ATE95697T1 (de) Uricosuretische zusammensetzung.
DK0622372T3 (da) Hidtil ukendt forbindelse, Leustroducsin H, dens fremstilling og dens terapeutiske anvendelse