ATE121385T1 - Harnstoffderivate, ihre herstellung und ihre verwendung bei der therapie. - Google Patents
Harnstoffderivate, ihre herstellung und ihre verwendung bei der therapie.Info
- Publication number
- ATE121385T1 ATE121385T1 AT92402131T AT92402131T ATE121385T1 AT E121385 T1 ATE121385 T1 AT E121385T1 AT 92402131 T AT92402131 T AT 92402131T AT 92402131 T AT92402131 T AT 92402131T AT E121385 T1 ATE121385 T1 AT E121385T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- therapy
- urea derivatives
- radical
- general formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/30—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by halogen atoms, or by nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/46—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylureas
- C07C275/48—Y being a hydrogen or a carbon atom
- C07C275/54—Y being a carbon atom of a six-membered aromatic ring, e.g. benzoylureas
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/18—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9109446A FR2679555B1 (fr) | 1991-07-25 | 1991-07-25 | Nouveaux derives de l'uree, leur preparation et leur application en therapeutique. |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE121385T1 true ATE121385T1 (de) | 1995-05-15 |
Family
ID=9415541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92402131T ATE121385T1 (de) | 1991-07-25 | 1992-07-23 | Harnstoffderivate, ihre herstellung und ihre verwendung bei der therapie. |
Country Status (8)
Country | Link |
---|---|
US (1) | US5288758A (de) |
EP (1) | EP0526313B1 (de) |
JP (1) | JPH05194359A (de) |
AT (1) | ATE121385T1 (de) |
DE (1) | DE69202120T2 (de) |
DK (1) | DK0526313T3 (de) |
ES (1) | ES2073258T3 (de) |
FR (1) | FR2679555B1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0640081B1 (de) * | 1992-03-31 | 2000-01-12 | Glaxo Group Limited | Substituierte phenylcarbamate und phenylharnstoffe, ihre herstellung und ihre verwendung als 5-ht4-antagonisten |
GB9206989D0 (en) * | 1992-03-31 | 1992-05-13 | Glaxo Group Ltd | Chemical compounds |
CA2189964A1 (en) * | 1994-05-18 | 1995-11-23 | Haruhiko Kikuchi | Novel diaminomethylidene derivative |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
CN1535682A (zh) | 1998-09-30 | 2004-10-13 | ����ҩƷ��ҵ��ʽ���� | 改善膀胱排泄能力的药物 |
WO2005080322A1 (ja) * | 2004-02-20 | 2005-09-01 | Astellas Pharma Inc. | フルオレン誘導体 |
WO2005079845A1 (ja) * | 2004-02-20 | 2005-09-01 | Astellas Pharma Inc. | 片頭痛予防薬 |
US20080171788A1 (en) * | 2005-02-08 | 2008-07-17 | Shinobu Akuzawa | Medicament For Irritable Bowel Syndrome |
US8076348B2 (en) * | 2005-08-08 | 2011-12-13 | Astellas Pharma Inc. | Acylguanidine derivative or salt thereof |
PE20070797A1 (es) * | 2005-11-25 | 2007-09-27 | Basf Ag | Compuestos de indanil- y tetrahidronaftil-amino-tiourea para combatir pestes animales |
JP6082250B2 (ja) | 2010-02-09 | 2017-02-15 | ザ・ジョンズ・ホプキンス・ユニバーシティー | 認知機能を改善するための方法および組成物 |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
WO2014144663A1 (en) | 2013-03-15 | 2014-09-18 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
EP2968220B1 (de) | 2013-03-15 | 2021-05-05 | Agenebio, Inc. | Verfahren und zusammensetzungen zur verbesserung von kognitiven funktionen |
CA2986598C (en) | 2015-05-22 | 2023-09-26 | Agenebio, Inc. | Extended release pharmaceutical compositions of levetiracetam |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3061640A (en) * | 1959-03-30 | 1962-10-30 | Monsanto Chemicals | 3, 4-dichlorophenyl dialkylaminoalkyl ureas and thioureas |
US3049562A (en) * | 1961-03-09 | 1962-08-14 | American Cyanamid Co | 1-(aralkyl, lower alkylamino lower alkyl), 1-phenyl, 3, 3-dilower alkylureas |
US3903154A (en) * | 1973-08-03 | 1975-09-02 | Chevron Res | Herbicidal substituted-haloethyl urea |
JPH0140026B2 (de) * | 1978-07-03 | 1989-08-24 | Amerikan Hoomu Purodakutsu Corp | |
US4474707A (en) * | 1980-10-09 | 1984-10-02 | American Home Products Corporation | N-3-Propenylaminopropyl-N'-phenylureas |
US4297373A (en) * | 1980-10-09 | 1981-10-27 | American Home Products Corporation | Method of suppressing cardiac arrhythmias |
US5015644A (en) * | 1987-06-02 | 1991-05-14 | Warner-Lambert Company | Antihyperlipidemic and antiatherosclerotic urea and carbamate compounds |
US5116848A (en) * | 1988-03-30 | 1992-05-26 | Warner-Lambert Company | N-(((2,6-disubstituted)phenyl)-n-diarylalkyl)ureas as antihyperlipidemic and antiatherosclerotic agents |
US5106873A (en) * | 1990-06-26 | 1992-04-21 | Warner-Lambert Company | ACAT inhibitors |
-
1991
- 1991-07-25 FR FR9109446A patent/FR2679555B1/fr not_active Expired - Fee Related
-
1992
- 1992-07-22 US US07/918,424 patent/US5288758A/en not_active Expired - Fee Related
- 1992-07-23 ES ES92402131T patent/ES2073258T3/es not_active Expired - Lifetime
- 1992-07-23 JP JP4197005A patent/JPH05194359A/ja not_active Withdrawn
- 1992-07-23 EP EP92402131A patent/EP0526313B1/de not_active Expired - Lifetime
- 1992-07-23 DK DK92402131.4T patent/DK0526313T3/da active
- 1992-07-23 AT AT92402131T patent/ATE121385T1/de not_active IP Right Cessation
- 1992-07-23 DE DE69202120T patent/DE69202120T2/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0526313B1 (de) | 1995-04-19 |
FR2679555A1 (fr) | 1993-01-29 |
US5288758A (en) | 1994-02-22 |
EP0526313A1 (de) | 1993-02-03 |
DK0526313T3 (da) | 1995-08-21 |
ES2073258T3 (es) | 1995-08-01 |
DE69202120D1 (de) | 1995-05-24 |
DE69202120T2 (de) | 1995-11-30 |
JPH05194359A (ja) | 1993-08-03 |
FR2679555B1 (fr) | 1993-11-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |