NO920050D0 - Trifluormetyl-1-karba(1-detia)cefemer - Google Patents

Trifluormetyl-1-karba(1-detia)cefemer

Info

Publication number
NO920050D0
NO920050D0 NO920050A NO920050A NO920050D0 NO 920050 D0 NO920050 D0 NO 920050D0 NO 920050 A NO920050 A NO 920050A NO 920050 A NO920050 A NO 920050A NO 920050 D0 NO920050 D0 NO 920050D0
Authority
NO
Norway
Prior art keywords
dethia
carba
cephem
trifluoromethyl
Prior art date
Application number
NO920050A
Other languages
English (en)
Other versions
NO920050L (no
Inventor
Gwendolyn Kay Cook
William Joseph Hornback
Iii John Hampton Mcdonald
John Edwin Munroe
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO920050D0 publication Critical patent/NO920050D0/no
Publication of NO920050L publication Critical patent/NO920050L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
    • C07D463/16—Nitrogen atoms
    • C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
    • C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO92920050A 1991-01-10 1992-01-03 Trifluormetyl-1-karba(1-detia)cefemer NO920050L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/639,475 US5099015A (en) 1991-01-10 1991-01-10 Trifluoromethyl 1-carba(1-dethia)cephems

Publications (2)

Publication Number Publication Date
NO920050D0 true NO920050D0 (no) 1992-01-03
NO920050L NO920050L (no) 1992-07-13

Family

ID=24564249

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92920050A NO920050L (no) 1991-01-10 1992-01-03 Trifluormetyl-1-karba(1-detia)cefemer

Country Status (21)

Country Link
US (1) US5099015A (no)
EP (1) EP0494733A1 (no)
JP (1) JPH05140160A (no)
KR (1) KR920014809A (no)
CN (1) CN1063104A (no)
AU (1) AU640072B2 (no)
BR (1) BR9200004A (no)
CA (1) CA2058699A1 (no)
CS (1) CS792A3 (no)
FI (1) FI920019A (no)
HU (1) HUT60267A (no)
IE (1) IE920021A1 (no)
IL (1) IL100573A (no)
MX (1) MX9200017A (no)
NO (1) NO920050L (no)
NZ (1) NZ241160A (no)
PT (1) PT99969A (no)
RU (1) RU2089551C1 (no)
TW (1) TW213912B (no)
YU (1) YU200791A (no)
ZA (1) ZA9222B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9305837D0 (en) * 1993-03-20 1993-05-05 Smithkline Beecham Plc Novel compounds
US5525599A (en) * 1993-07-21 1996-06-11 Eli Lilly And Company 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids
AU2003298513A1 (en) * 2002-05-14 2004-05-13 Northwestern University STERICALLY-AWKWARD Beta-LACTAMASE INHIBITORS
US20050245498A1 (en) * 2002-05-14 2005-11-03 Shoichet Brian K Sterically-awkward beta-lactamase inhibitors
RU2462450C2 (ru) * 2005-09-22 2012-09-27 Мейдзи Сейка Кайся, Лтд. ИНГИБИТОРЫ МЕТАЛЛО-β-ЛАКТАМАЗЫ

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347367A (en) * 1977-10-19 1982-08-31 Merck & Co., Inc. 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid
NO155547C (no) * 1979-02-10 1987-04-15 Kyowa Hakko Kogyo Kk Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling.
EP0025602B1 (en) * 1979-09-13 1984-12-19 Kyowa Hakko Kogyo Co., Ltd Acylated cephalosporin analogs, process for their preparation and pharmaceutical compositions comprising them
JPS5842860B2 (ja) * 1979-10-12 1983-09-22 三菱瓦斯化学株式会社 ２−ペンテン酸エステルの製造方法
AU6235580A (en) * 1979-10-25 1982-07-29 Kyowa Hakko Kogyo Co. Ltd. Cephalosporin analogs
JPS5849382A (ja) * 1981-09-18 1983-03-23 Kyowa Hakko Kogyo Co Ltd β−ラクタム化合物
JPS60174787A (ja) * 1984-02-21 1985-09-09 Kyowa Hakko Kogyo Co Ltd ３位置換カルバセフエム化合物
US4673737A (en) * 1985-08-02 1987-06-16 Harvard University 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof
US4708956A (en) * 1985-12-12 1987-11-24 Kyowa Hakko Kogyo Co., Ltd. 3-position halogenated cephalosporin analogs and pharmaceutical compositions
EP0301877B1 (en) * 1987-07-31 1993-04-14 Eli Lilly And Company A method of deprotection of 3-amino azetidinones
DE3803169A1 (de) * 1988-02-03 1989-08-17 Bayer Ag Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln

Also Published As

Publication number Publication date
NO920050L (no) 1992-07-13
CA2058699A1 (en) 1992-07-11
AU640072B2 (en) 1993-08-12
TW213912B (no) 1993-10-01
HU9200011D0 (en) 1992-03-30
HUT60267A (en) 1992-08-28
YU200791A (sh) 1994-01-20
IL100573A (en) 1997-01-10
JPH05140160A (ja) 1993-06-08
CS792A3 (en) 1992-07-15
FI920019A (fi) 1992-07-11
CN1063104A (zh) 1992-07-29
BR9200004A (pt) 1992-09-08
EP0494733A1 (en) 1992-07-15
AU1001192A (en) 1992-07-16
RU2089551C1 (ru) 1997-09-10
IE920021A1 (en) 1992-07-15
PT99969A (pt) 1993-02-26
NZ241160A (en) 1994-04-27
KR920014809A (ko) 1992-08-25
FI920019A0 (fi) 1992-01-02
US5099015A (en) 1992-03-24
MX9200017A (es) 1992-07-01
IL100573A0 (en) 1992-09-06
ZA9222B (en) 1993-07-02

Similar Documents

Publication Publication Date Title
ATE137279T1 (de) Stoffauflauf
ATA131391A (de) Reibring
BR9204511A (pt) Recolhedor-enrolador
NO923755L (no) Sportsstoevel
FI934710A (fi) 4-aryl-3-(heteroarylureido)kinolinderivat
FI934447A0 (fi) Nytt immunhaemmande aemne fraon strptomyces braegensis
ATA170491A (de) Mauerstein
ATA39792A (de) Maehwerk
NO920050D0 (no) Trifluormetyl-1-karba(1-detia)cefemer
FI930257A (fi) Skivfilter
ATE163916T1 (de) Ethyl-6-formyloxy-4-hexenoat
ATA67791A (de) Rollski
ATA9892A (de) Formstein
NO922920D0 (no) Froebehandlingsmiddel
KR920019121U (ko) 도마
KR930010369U (ko) 도마
CA68725S (fr) Mobilier-jeu
ITRE910005V0 (it) Supporto - lombare
BR7101342U (pt) Hamburgueira
ATA23591A (de) Muenzkassa
NO923671D0 (no) Sirkelverktoey-anordning
ATA235591A (de) Eluiergeraet
ATA188391A (de) Alpinski
BR7100567U (pt) Auto-transponder
BR9102019A (pt) Brazbloc