ZA9222B - Trifluoromethyl 1-carba(1-dethia)cephems. - Google Patents
Trifluoromethyl 1-carba(1-dethia)cephems.Info
- Publication number
- ZA9222B ZA9222B ZA9222A ZA9222A ZA9222B ZA 9222 B ZA9222 B ZA 9222B ZA 9222 A ZA9222 A ZA 9222A ZA 9222 A ZA9222 A ZA 9222A ZA 9222 B ZA9222 B ZA 9222B
- Authority
- ZA
- South Africa
- Prior art keywords
- dethia
- cephems
- carba
- trifluoromethyl
- Prior art date
Links
- 150000001782 cephems Chemical class 0.000 title 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D463/00—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D463/10—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D463/14—Heterocyclic compounds containing 1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hetero atoms directly attached in position 7
- C07D463/16—Nitrogen atoms
- C07D463/18—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof
- C07D463/20—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D463/22—Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/639,475 US5099015A (en) | 1991-01-10 | 1991-01-10 | Trifluoromethyl 1-carba(1-dethia)cephems |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA9222B true ZA9222B (en) | 1993-07-02 |
Family
ID=24564249
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA9222A ZA9222B (en) | 1991-01-10 | 1992-01-02 | Trifluoromethyl 1-carba(1-dethia)cephems. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5099015A (xx) |
EP (1) | EP0494733A1 (xx) |
JP (1) | JPH05140160A (xx) |
KR (1) | KR920014809A (xx) |
CN (1) | CN1063104A (xx) |
AU (1) | AU640072B2 (xx) |
BR (1) | BR9200004A (xx) |
CA (1) | CA2058699A1 (xx) |
CS (1) | CS792A3 (xx) |
FI (1) | FI920019A (xx) |
HU (1) | HUT60267A (xx) |
IE (1) | IE920021A1 (xx) |
IL (1) | IL100573A (xx) |
MX (1) | MX9200017A (xx) |
NO (1) | NO920050L (xx) |
NZ (1) | NZ241160A (xx) |
PT (1) | PT99969A (xx) |
RU (1) | RU2089551C1 (xx) |
TW (1) | TW213912B (xx) |
YU (1) | YU200791A (xx) |
ZA (1) | ZA9222B (xx) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9305837D0 (en) * | 1993-03-20 | 1993-05-05 | Smithkline Beecham Plc | Novel compounds |
US5525599A (en) * | 1993-07-21 | 1996-06-11 | Eli Lilly And Company | 7-substituted-amino-3-substituted-3-cephem-4-carboxylic acids |
WO2004037163A2 (en) * | 2002-05-14 | 2004-05-06 | Northwestern University | STERICALLY-AWKWARD β-LACTAMASE INHIBITORS |
US20050245498A1 (en) * | 2002-05-14 | 2005-11-03 | Shoichet Brian K | Sterically-awkward beta-lactamase inhibitors |
CN101267815B (zh) * | 2005-09-22 | 2013-11-06 | 明治制果药业株式会社 | 金属-β-内酰胺酶抑制剂 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4347367A (en) * | 1977-10-19 | 1982-08-31 | Merck & Co., Inc. | 3-Substituted-6-(1'-hydroxyethyl)-7-oxo-1-azabicyclo[3.2.0]-hept-2-ene-2-carboxylic acid |
NO155547C (no) * | 1979-02-10 | 1987-04-15 | Kyowa Hakko Kogyo Kk | Optisk aktive cefalosporin-analoge og salter derav samt fremgangsmaate for deres fremstilling. |
DK389080A (da) * | 1979-09-13 | 1981-03-14 | Kyowa Hakko Kogyo Kk | Fremgangsmaade til fremstilling af racemiske eller optisk aktive cephalosporin-analoge carbacephemforbindelser eller farmaceutisk accepable salte deraf |
JPS5842860B2 (ja) * | 1979-10-12 | 1983-09-22 | 三菱瓦斯化学株式会社 | 2−ペンテン酸エステルの製造方法 |
EP0027882B1 (en) * | 1979-10-25 | 1985-01-02 | Kyowa Hakko Kogyo Co., Ltd | Optically active cephalosporin analogs, process for their preparation and their use |
JPS5849382A (ja) * | 1981-09-18 | 1983-03-23 | Kyowa Hakko Kogyo Co Ltd | β−ラクタム化合物 |
JPS60174787A (ja) * | 1984-02-21 | 1985-09-09 | Kyowa Hakko Kogyo Co Ltd | 3位置換カルバセフエム化合物 |
US4673737A (en) * | 1985-08-02 | 1987-06-16 | Harvard University | 7-acylamino-(or 7-amino)-3-trifluoromethylsulfonyloxy-1-carba(1-dethia)-3-cephem-4-carboxylic acids and esters thereof |
US4708956A (en) * | 1985-12-12 | 1987-11-24 | Kyowa Hakko Kogyo Co., Ltd. | 3-position halogenated cephalosporin analogs and pharmaceutical compositions |
DE3880229T2 (de) * | 1987-07-31 | 1993-08-12 | Lilly Co Eli | Verfahren zum entschuetzen von 3-aminoazetidinonen. |
DE3803169A1 (de) * | 1988-02-03 | 1989-08-17 | Bayer Ag | Ss-lactam-antibiotika, verfahren zu ihrer herstellung und ihre verwendung als und in arzneimitteln |
-
1991
- 1991-01-10 US US07/639,475 patent/US5099015A/en not_active Expired - Fee Related
- 1991-12-23 NZ NZ241160A patent/NZ241160A/en unknown
- 1991-12-27 JP JP3360564A patent/JPH05140160A/ja not_active Withdrawn
- 1991-12-30 YU YU200791A patent/YU200791A/sh unknown
-
1992
- 1992-01-01 IL IL10057392A patent/IL100573A/xx not_active IP Right Cessation
- 1992-01-02 CS CS927A patent/CS792A3/cs unknown
- 1992-01-02 FI FI920019A patent/FI920019A/fi not_active Application Discontinuation
- 1992-01-02 CA CA002058699A patent/CA2058699A1/en not_active Abandoned
- 1992-01-02 HU HU9200011A patent/HUT60267A/hu unknown
- 1992-01-02 ZA ZA9222A patent/ZA9222B/xx unknown
- 1992-01-02 BR BR929200004A patent/BR9200004A/pt not_active Application Discontinuation
- 1992-01-02 AU AU10011/92A patent/AU640072B2/en not_active Ceased
- 1992-01-02 PT PT99969A patent/PT99969A/pt not_active Application Discontinuation
- 1992-01-03 EP EP92300040A patent/EP0494733A1/en not_active Withdrawn
- 1992-01-03 CN CN92100039A patent/CN1063104A/zh active Pending
- 1992-01-03 MX MX9200017A patent/MX9200017A/es unknown
- 1992-01-03 TW TW081100001A patent/TW213912B/zh active
- 1992-01-03 RU SU925010586A patent/RU2089551C1/ru active
- 1992-01-03 KR KR1019920000009A patent/KR920014809A/ko not_active Application Discontinuation
- 1992-01-03 NO NO92920050A patent/NO920050L/no unknown
- 1992-01-03 IE IE002192A patent/IE920021A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0494733A1 (en) | 1992-07-15 |
TW213912B (xx) | 1993-10-01 |
HU9200011D0 (en) | 1992-03-30 |
HUT60267A (en) | 1992-08-28 |
RU2089551C1 (ru) | 1997-09-10 |
NZ241160A (en) | 1994-04-27 |
US5099015A (en) | 1992-03-24 |
KR920014809A (ko) | 1992-08-25 |
IL100573A0 (en) | 1992-09-06 |
FI920019A (fi) | 1992-07-11 |
BR9200004A (pt) | 1992-09-08 |
NO920050L (no) | 1992-07-13 |
FI920019A0 (fi) | 1992-01-02 |
IE920021A1 (en) | 1992-07-15 |
YU200791A (xx) | 1994-01-20 |
CA2058699A1 (en) | 1992-07-11 |
NO920050D0 (no) | 1992-01-03 |
JPH05140160A (ja) | 1993-06-08 |
PT99969A (pt) | 1993-02-26 |
AU1001192A (en) | 1992-07-16 |
CS792A3 (en) | 1992-07-15 |
AU640072B2 (en) | 1993-08-12 |
CN1063104A (zh) | 1992-07-29 |
IL100573A (en) | 1997-01-10 |
MX9200017A (es) | 1992-07-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA92908B (en) | Compounds. | |
PH31071A (en) | Substituted pyrridopyrimidines useful antgiotensinII antagonists. | |
ZA929790B (en) | Imidazopyridines. | |
ZA929517B (en) | Compounds. | |
ZA927129B (en) | Soldering. | |
DE59204008D1 (en) | Trachealstent. | |
GR3014994T3 (en) | Transmission. | |
ZA926482B (en) | Cyanophenylpyrroles. | |
ZA927792B (en) | Anti-alpha6-integrin-antibodies. | |
EP0666851A4 (en) | Substituted phthalazinones as nerotensin antagonists. | |
EP0668864A4 (en) | SUBSTITUTED BIPHENYLMETHYLIMIDAZOPYRIDINES. | |
ZA928822B (en) | Telecomnnunications network. | |
ZA929375B (en) | N-aryl-nitrogen heterocycles. | |
OA09716A (en) | Benzoxaiole derivatives. | |
ZA927997B (en) | Pyrazolines. | |
EP0576606A4 (en) | RESIDUAL PROTEASE-III. | |
DE69205795D1 (en) | Mesoprotheseunterlage. | |
ZA927998B (en) | Pyrazolines. | |
EP0572573A4 (en) | Thyroid-derived chondrocyte-stimulating factor. | |
ZA926706B (en) | Heterocyclically substituted quinolylmethoxy-phenylacetamides. | |
ZA9222B (en) | Trifluoromethyl 1-carba(1-dethia)cephems. | |
ZA925185B (en) | Dithianes. | |
DE69203865D1 (en) | Thermo-transferdrucksystem. | |
DE69204801D1 (en) | Hydroxy- oder oxosubstituierte alkylcyclopentene. | |
ZA929820B (en) | Heisswinderschieber. |