NO915036L - Analogifremgangsmaate for fremstilling av terapeutisk virksomme 1,3-dioxolanderivater - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk virksomme 1,3-dioxolanderivater

Info

Publication number
NO915036L
NO915036L NO91915036A NO915036A NO915036L NO 915036 L NO915036 L NO 915036L NO 91915036 A NO91915036 A NO 91915036A NO 915036 A NO915036 A NO 915036A NO 915036 L NO915036 L NO 915036L
Authority
NO
Norway
Prior art keywords
lower alkyl
hydrogen
dioxolander
derivatives
preparation
Prior art date
Application number
NO91915036A
Other languages
English (en)
Other versions
NO915036D0 (no
NO179006B (no
NO179006C (no
Inventor
Keith A M Walker
Pamela M Burton
David C Swinney
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of NO915036D0 publication Critical patent/NO915036D0/no
Publication of NO915036L publication Critical patent/NO915036L/no
Publication of NO179006B publication Critical patent/NO179006B/no
Publication of NO179006C publication Critical patent/NO179006C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
NO915036A 1990-12-20 1991-12-19 Analogifremgangsmåte for fremstilling av terapeutisk virksomme 1,3-dioxolanderivater NO179006C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/633,599 US5158949A (en) 1990-12-20 1990-12-20 1,3-dioxolane derivatives as cholesterol-lowering agents

Publications (4)

Publication Number Publication Date
NO915036D0 NO915036D0 (no) 1991-12-19
NO915036L true NO915036L (no) 1992-06-22
NO179006B NO179006B (no) 1996-04-09
NO179006C NO179006C (no) 1996-07-17

Family

ID=24540306

Family Applications (1)

Application Number Title Priority Date Filing Date
NO915036A NO179006C (no) 1990-12-20 1991-12-19 Analogifremgangsmåte for fremstilling av terapeutisk virksomme 1,3-dioxolanderivater

Country Status (21)

Country Link
US (1) US5158949A (no)
EP (1) EP0492474B1 (no)
JP (1) JPH04308588A (no)
KR (1) KR920011484A (no)
AT (1) ATE149495T1 (no)
AU (1) AU650079B2 (no)
CA (1) CA2058068A1 (no)
DE (1) DE69124956T2 (no)
DK (1) DK0492474T3 (no)
FI (1) FI916018A (no)
GR (1) GR3022740T3 (no)
HU (2) HUT61998A (no)
IE (1) IE914442A1 (no)
IL (1) IL100430A (no)
IT (1) IT1250362B (no)
MX (1) MX9102703A (no)
NO (1) NO179006C (no)
NZ (1) NZ241068A (no)
PT (1) PT99859A (no)
TW (1) TW230208B (no)
ZA (1) ZA9110019B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208331A (en) * 1992-06-18 1993-05-04 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
US5274108A (en) * 1992-06-18 1993-12-28 Syntex (U.S.A.) Inc. Process for preparing 1,3-dioxolane derivatives
KR100331609B1 (ko) * 1995-04-21 2002-11-18 성 렬 류 신규한시스-튜불라졸유도체및그의제조방법
KR100704710B1 (ko) * 1999-10-29 2007-04-09 주식회사 중외제약 간 섬유화 억제작용을 나타내는 벤조[3,4-ｄ]1,3-디옥솔란 유도체
WO2008151437A1 (en) * 2007-06-14 2008-12-18 Osta Biotechnologies Heme-oxygenase inhibitors and use of the same in the treatment of cancer and diseases of the central nervous system
BR112019006451A2 (pt) * 2016-09-29 2019-06-25 Bayer Ag derivados substituídos de 1,5 imidazóis como fungicidas para proteção de plantação.
KR20210040945A (ko) 2018-06-21 2021-04-14 유마니티 테라퓨틱스, 인크. 신경장애의 치료 및 예방을 위한 조성물 및 방법

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4078071A (en) * 1976-03-08 1978-03-07 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkyl imidazoles
US4144346A (en) * 1977-01-31 1979-03-13 Janssen Pharmaceutica N.V. Novel 1-(1,3-dioxolan-2-ylmethyl)-1H-imidazoles
US4321272A (en) * 1980-08-25 1982-03-23 Syntex (U.S.A.) Inc. Derivatives of substituted N-alkylimidazoles
EP0052905B1 (en) * 1980-11-24 1984-10-03 Janssen Pharmaceutica N.V. Novel (2-aryl-4-phenylthioalkyl-1,3-dioxolan-2-yl-methyl)azole derivatives
US4490540A (en) * 1981-09-14 1984-12-25 Janssen Pharmaceutica N.V. (2-Aryl-4-phenylthioalkyl-1,3-dioxolan-2-ylmethyl)azole derivatives
US4359475A (en) * 1981-12-21 1982-11-16 Syntex (U.S.A.) Inc. Thioketal substituted N-alkyl imidazoles
US4375474A (en) * 1982-02-11 1983-03-01 Syntex (U.S.A.) Inc. Dioxalane containing imidazole compounds, compositions and use
DK305884A (da) * 1983-06-24 1984-12-25 Yamanouchi Pharma Co Ltd Phenoxyderivat, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende et saadant derivat
US4518607A (en) * 1983-07-18 1985-05-21 Syntex (U.S.A.) Inc. Male oral contraceptive N-alkylimidazole derivatives, compositions, and method of use therefor
US4940799A (en) * 1987-07-20 1990-07-10 Ciba-Geigy Corporation Preparation of the diastereomeric mixture 2R,4S-1-[2-(2,4-dichlorophenyl)-4-n-propyl-1,3-dioxolan-2-ylmethyl]-1H-1,2,4-triazole
AU614818B2 (en) * 1988-03-28 1991-09-12 Janssen Pharmaceutica N.V. 2-imidazolylmethyl-1,3-dioxolanyl methylthiophenyl carbamate derivatives and their use as antineoplastic agents

Also Published As

Publication number Publication date
IL100430A (en) 1997-03-18
ZA9110019B (en) 1993-06-21
GR3022740T3 (en) 1997-06-30
DE69124956D1 (de) 1997-04-10
EP0492474B1 (en) 1997-03-05
HUT61998A (en) 1993-03-29
PT99859A (pt) 1992-12-31
IE914442A1 (en) 1992-07-01
CA2058068A1 (en) 1992-06-21
HU210718A9 (en) 1995-06-28
FI916018A (fi) 1992-06-21
ATE149495T1 (de) 1997-03-15
EP0492474A1 (en) 1992-07-01
ITTO910999A1 (it) 1992-06-21
US5158949A (en) 1992-10-27
IT1250362B (it) 1995-04-07
AU8990591A (en) 1992-06-25
JPH04308588A (ja) 1992-10-30
NO915036D0 (no) 1991-12-19
NO179006B (no) 1996-04-09
MX9102703A (es) 1992-06-01
DE69124956T2 (de) 1997-06-12
DK0492474T3 (da) 1997-03-24
IL100430A0 (en) 1992-09-06
AU650079B2 (en) 1994-06-09
HU914024D0 (en) 1992-03-30
ITTO910999A0 (it) 1991-12-19
TW230208B (no) 1994-09-11
NZ241068A (en) 1996-12-20
KR920011484A (ko) 1992-07-24
NO179006C (no) 1996-07-17
FI916018A0 (fi) 1991-12-19

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