NO912902L - Nye vitamin d-analoger. - Google Patents

Nye vitamin d-analoger.

Info

Publication number
NO912902L
NO912902L NO91912902A NO912902A NO912902L NO 912902 L NO912902 L NO 912902L NO 91912902 A NO91912902 A NO 91912902A NO 912902 A NO912902 A NO 912902A NO 912902 L NO912902 L NO 912902L
Authority
NO
Norway
Prior art keywords
formula
compounds
groups
diseases
present
Prior art date
Application number
NO91912902A
Other languages
English (en)
Other versions
NO178065C (no
NO178065B (no
NO912902D0 (no
Inventor
Martin John Calverley
Kai Hansen
Lise Binderup
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Publication of NO912902L publication Critical patent/NO912902L/no
Publication of NO912902D0 publication Critical patent/NO912902D0/no
Publication of NO178065B publication Critical patent/NO178065B/no
Publication of NO178065C publication Critical patent/NO178065C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO912902A 1989-02-23 1991-07-25 Analogifremgangsmåte ved fremstilling av terapeutisk aktive nye vitamin D-analoger, samt mellomprodukt NO178065C (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898904154A GB8904154D0 (en) 1989-02-23 1989-02-23 Chemical compounds
PCT/DK1990/000036 WO1990009991A1 (en) 1989-02-23 1990-02-13 Novel vitamin d analogues
SG131794A SG131794G (en) 1989-02-23 1994-09-12 Novel vitamin D analogues

Publications (4)

Publication Number Publication Date
NO912902L true NO912902L (no) 1991-07-25
NO912902D0 NO912902D0 (no) 1991-07-25
NO178065B NO178065B (no) 1995-10-09
NO178065C NO178065C (no) 1996-01-17

Family

ID=26295003

Family Applications (1)

Application Number Title Priority Date Filing Date
NO912902A NO178065C (no) 1989-02-23 1991-07-25 Analogifremgangsmåte ved fremstilling av terapeutisk aktive nye vitamin D-analoger, samt mellomprodukt

Country Status (22)

Country Link
EP (1) EP0460032B1 (no)
JP (1) JP2807083B2 (no)
KR (1) KR0163194B1 (no)
AT (1) ATE104957T1 (no)
AU (1) AU627001B2 (no)
CA (1) CA2044280C (no)
DE (1) DE69008517T2 (no)
DK (1) DK0460032T3 (no)
ES (1) ES2055905T3 (no)
FI (1) FI92929C (no)
GB (1) GB8904154D0 (no)
HK (1) HK128894A (no)
HU (1) HU211025B (no)
IE (1) IE63123B1 (no)
LT (1) LT3983B (no)
LV (1) LV10428B (no)
NO (1) NO178065C (no)
PT (1) PT93232B (no)
RO (1) RO109939B1 (no)
RU (1) RU2037484C1 (no)
SG (1) SG131794G (no)
WO (1) WO1990009991A1 (no)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8904153D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds
DE4011682A1 (de) * 1990-04-06 1991-10-10 Schering Ag 24-oxa-derivate in der vitamin d-reihe
GB9015774D0 (en) * 1990-07-18 1990-09-05 Leo Pharm Prod Ltd Novel treatment
US5486509A (en) * 1991-06-28 1996-01-23 University Of Miami Method of preventing and treating chemotherapy-induced alopecia
AU666563B2 (en) * 1992-08-07 1996-02-15 Wisconsin Alumni Research Foundation Preparation of 19-nor-vitamin D compounds
GB9220272D0 (en) * 1992-09-25 1992-11-11 Leo Pharm Prod Ltd Chemical compounds
GB9220439D0 (en) * 1992-09-28 1992-11-11 Leo Pharm Prod Ltd Chemical compounds
US5449668A (en) * 1993-06-04 1995-09-12 Duphar International Research B.V. Vitamin D compounds and method of preparing these compounds
US6392071B1 (en) 1997-03-17 2002-05-21 Wisconsin Alumni: Research Foundation 26,27-homologated-20-EPI-2-alkylidene-19-nor-vitamin D compounds
US6316642B1 (en) 1997-03-17 2001-11-13 Wisconsin Alumni Research Foundation 26,27-Homologated-20-EPI-2alkyl-19-nor-vitamin D compounds
US5945410A (en) 1997-03-17 1999-08-31 Wisconsin Alumni Research Foundation 2-alkyl-19-nor-vitamin D compounds
US6306844B1 (en) 1997-03-17 2001-10-23 Wisconsin Alumni Research Foundation Use of 2α-methyl-19-nor-20(S)-1α, 25-dihydroxyvitamin D3 to increase bone strength
US5939406A (en) 1997-07-21 1999-08-17 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US6359152B2 (en) 1997-07-21 2002-03-19 Wisconsin Alumni Research Foundation 18-substituted-19-nor-vitamin D compounds
US5962707A (en) * 1998-08-18 1999-10-05 Wisconsin Alumni Research Foundation 19-nor-vitamin D3 compounds with calcemic activity
EP1275643A4 (en) * 2000-04-19 2009-06-03 Chugai Pharmaceutical Co Ltd DERIVATIVES OF VITAMIN D
US20030018017A1 (en) * 2001-01-25 2003-01-23 Deluca Hector F. Method of treatment of type I diabetes
ATE556999T1 (de) 2003-04-10 2012-05-15 Wisconsin Alumni Res Found 2-propyliden-19-nor-vitamin d verbindungen
US6894037B2 (en) 2003-07-03 2005-05-17 Wisconsin Alumni Research Foundation 2-methylene-19-nor-20(S)-25-methyl-1α-hydroxycalciferol and its uses
US7713951B2 (en) 2004-04-09 2010-05-11 Wisconsin Alumni Research Foundation 2-alkylidene-18,19-dinor-vitamin D compounds
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
US8058265B2 (en) 2006-04-05 2011-11-15 Wisconsin Alumni Research Foundation 1a-hydroxy-2-(3'-hydroxypropylidene)-19-nor-vitamin D compounds and methods of making and treatment thereof
US8377913B2 (en) * 2007-11-20 2013-02-19 Abbvie Inc. Vitamin D receptor activators and methods of making
JP5563324B2 (ja) * 2010-02-03 2014-07-30 フォーモサ・ラボラトリーズ・インコーポレーテッド マキサカルシトール中間体およびその製造方法
JP2014514274A (ja) 2011-03-09 2014-06-19 テバ ファーマシューティカル インダストリーズ リミティド マキサカルシトールの多形およびマキサカルシトールの調製方法
CN102796134B (zh) * 2012-08-31 2015-07-01 甘肃皓天化学科技有限公司 一种马沙骨化醇中间体的制备方法
CN103910666A (zh) * 2014-04-15 2014-07-09 湖南华腾制药有限公司 一种制备马沙骨化醇的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL67153A (en) 1981-11-02 1986-12-31 Res Inst Medicine Chem Intermediates in the production of vitamin d analogues and method for their production
CA1332841C (en) * 1984-11-27 1994-11-01 Noboru Kubodera Vitamin d derivatives and process for producing the same
JPH07100685B2 (ja) 1985-08-02 1995-11-01 レオ・ファ−マシュ−ティカル・プロダクツ・リミテッド・エイ／エス（レ−ベンス・ケミスケ・ファブリック・プロデュクチオンスアクチ−セルスカブ） 新規ビタミンｄ類似体
AU614372B2 (en) 1988-04-21 1991-08-29 Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) Novel vitamin d analogues
GB8904153D0 (en) * 1989-02-23 1989-04-05 Leo Pharm Prod Ltd Chemical compounds

Also Published As

Publication number Publication date
RU2037484C1 (ru) 1995-06-19
JPH04503669A (ja) 1992-07-02
LV10428B (en) 1995-10-20
NO178065C (no) 1996-01-17
IE63123B1 (en) 1995-03-22
HK128894A (en) 1994-11-25
DE69008517D1 (de) 1994-06-01
EP0460032A1 (en) 1991-12-11
FI913812A0 (fi) 1991-08-12
EP0460032B1 (en) 1994-04-27
LT3983B (en) 1996-06-25
IE900421L (en) 1990-08-23
HU211025B (en) 1995-09-28
CA2044280C (en) 1999-12-21
DK0460032T3 (da) 1994-06-06
JP2807083B2 (ja) 1998-09-30
KR920701145A (ko) 1992-08-11
RO109939B1 (ro) 1995-07-28
FI92929C (fi) 1995-01-25
ES2055905T3 (es) 1994-09-01
CA2044280A1 (en) 1990-08-24
HUT59664A (en) 1992-06-29
LV10428A (lv) 1995-02-20
WO1990009991A1 (en) 1990-09-07
SG131794G (en) 1995-01-13
GB8904154D0 (en) 1989-04-05
FI92929B (fi) 1994-10-14
AU5198390A (en) 1990-09-26
ATE104957T1 (de) 1994-05-15
PT93232B (pt) 1995-12-29
PT93232A (pt) 1990-08-31
DE69008517T2 (de) 1994-08-18
LTIP1536A (en) 1995-09-25
AU627001B2 (en) 1992-08-13
NO178065B (no) 1995-10-09
NO912902D0 (no) 1991-07-25
KR0163194B1 (ko) 1999-01-15

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