NO911081L - Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler. - Google Patents

Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler.

Info

Publication number
NO911081L
NO911081L NO91911081A NO911081A NO911081L NO 911081 L NO911081 L NO 911081L NO 91911081 A NO91911081 A NO 91911081A NO 911081 A NO911081 A NO 911081A NO 911081 L NO911081 L NO 911081L
Authority
NO
Norway
Prior art keywords
ch2ph
alkyl
dialkylamino
procedure
preparation
Prior art date
Application number
NO91911081A
Other languages
English (en)
Norwegian (no)
Other versions
NO911081D0 (no
Inventor
Gerhard Jaehne
Manfred Roesner
Irvin Winkler
Matthias Helsberg
Thomas Scholl
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO911081D0 publication Critical patent/NO911081D0/no
Publication of NO911081L publication Critical patent/NO911081L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/24—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one nitrogen and one sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO91911081A 1990-03-20 1991-03-19 Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler. NO911081L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4008858A DE4008858A1 (de) 1990-03-20 1990-03-20 Substituierte purine, verfahren zu ihrer hertellung sowie ihre verwendung als antivirale mittel

Publications (2)

Publication Number Publication Date
NO911081D0 NO911081D0 (no) 1991-03-19
NO911081L true NO911081L (no) 1991-09-23

Family

ID=6402601

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91911081A NO911081L (no) 1990-03-20 1991-03-19 Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler.

Country Status (19)

Country Link
EP (1) EP0452680B1 (cs)
JP (1) JP3146423B2 (cs)
KR (1) KR910016751A (cs)
CN (1) CN1054982A (cs)
AT (1) ATE144984T1 (cs)
AU (1) AU644414B2 (cs)
CA (1) CA2038589A1 (cs)
CS (1) CS70891A2 (cs)
DE (2) DE4008858A1 (cs)
DK (1) DK0452680T3 (cs)
ES (1) ES2093651T3 (cs)
FI (1) FI911310A (cs)
GR (1) GR3021591T3 (cs)
HU (1) HUT57764A (cs)
IE (1) IE910908A1 (cs)
IL (1) IL97586A0 (cs)
NO (1) NO911081L (cs)
PT (1) PT97080A (cs)
ZA (1) ZA912015B (cs)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4210221A1 (de) * 1992-03-28 1993-09-30 Hoechst Ag Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung
EP0589335B1 (de) * 1992-09-24 2003-06-18 Hoechst Aktiengesellschaft N1-Substituierte 1H-1,2,3-Triazolo[4,5-d]pyrimidine, Verfahren zu ihrer Herstellung sowie ihre Verwendung als antivirale Mittel
DE4311801A1 (de) * 1993-04-09 1994-10-13 Hoechst Ag Neue Carbonsäureester von 2-Amino-7-(1,3-dihydroxy-2-propoxymethyl)purin, deren Herstellung sowie deren Verwendung
DE19536164A1 (de) * 1995-09-28 1997-04-03 Boehringer Ingelheim Kg Verbessertes Verfahren zur Herstellung von 9-[(2-Hyroxyethoxy)methyl]guanin (Acyclovir)
US5891881A (en) * 1997-11-21 1999-04-06 Clarion Pharmaceuticals Inc. Aminoheterocycle-substituted glycerols
FR2793794B1 (fr) * 1999-05-21 2001-07-27 Hoechst Marion Roussel Inc Nouveaux derives de la purine, leur procede de preparation, leur application a titre de medicaments, compositions pharmaceutiques et nouvelle utilisation
PE20030008A1 (es) 2001-06-19 2003-01-22 Bristol Myers Squibb Co Inhibidores duales de pde 7 y pde 4

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US4816447A (en) * 1981-08-26 1989-03-28 Merck & Co., Inc. Anti-viral guanine compounds
DE3627024A1 (de) * 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
AP160A (en) * 1987-08-15 1991-11-18 The Wellcome Foundation Ltd Therapeutic acyclic nucleosides.

Also Published As

Publication number Publication date
AU7351491A (en) 1991-09-26
FI911310A0 (fi) 1991-03-18
FI911310A (fi) 1991-09-21
ATE144984T1 (de) 1996-11-15
NO911081D0 (no) 1991-03-19
EP0452680B1 (de) 1996-11-06
HU910928D0 (en) 1991-10-28
GR3021591T3 (en) 1997-02-28
DK0452680T3 (da) 1997-04-07
KR910016751A (ko) 1991-11-05
DE59108319D1 (de) 1996-12-12
ES2093651T3 (es) 1997-01-01
PT97080A (pt) 1991-11-29
CA2038589A1 (en) 1991-09-21
IE910908A1 (en) 1991-09-25
CS70891A2 (en) 1991-11-12
EP0452680A1 (de) 1991-10-23
DE4008858A1 (de) 1991-09-26
JPH04217984A (ja) 1992-08-07
IL97586A0 (en) 1992-06-21
JP3146423B2 (ja) 2001-03-19
HUT57764A (en) 1991-12-30
AU644414B2 (en) 1993-12-09
ZA912015B (en) 1991-12-24
CN1054982A (zh) 1991-10-02

Similar Documents

Publication Publication Date Title
FI885623A (fi) Menetelmä lääkeaineina käyttökelpoisten substituoitujen propaani-fosfiinihappoyhdisteiden valmistamiseksi
PT97460A (pt) Processo para a preparacao de compostos anti-virus derivados de acido d-neuraminico e das suas formulacoes farmaceuticas
GR3036393T3 (en) ENANTIOMERICALLY PURE -g(b)-D-DIOXOLANE-NUCLEOSIDES.
IE872650L (en) Imidazopyridine derivatives, their production, and¹pharmaceutical compositions containing them
DE3376325D1 (en) Antiviral purine derivatives
NO911081D0 (no) Fremgangsmaate for fremstilling av substituerte puriner, og deres anvendelse som antivirale midler.
HUT57767A (en) Process for producing purine derivatives and pharmaceutical compositions comprising same
EP0310673A4 (en) 2'-alkylidenepyrimidine nucleoside derivatives, process for their preparation, and their use
EP0371139A4 (en) 6-substituted acyclicpyrimidine nucleoside derivatives and antiviral agents containing same as active ingredients
BG101523A (en) Method for the preparation of n-phosphonomethylglycine
AU2631188A (en) 9-(2-(Phosphonomethoxy)Ethoxy) Purine derivatives, intermediates and use as pharmaceuticals
ES2013379A6 (es) Procedimiento para preparar 6-sulfenamido-6, sulfinamido- y 6-sulfonamido-purinas, nucleosidos de purinas y nucleotidos de purinas antitumorales.
ATE151069T1 (de) Verfahren zur herstellung von kohlenhydrat- tensiden und ihren vorläufern
GB2016002A (en) Amino derivatives of pyrazolo[1,5-A]S.triazine
HU896136D0 (en) Process for producing compounds with antiviral effect and pharmaceutical compositions comprising same