NO895028D0 - Ny chimerisk transformerende vekstfaktor-beta. - Google Patents

Ny chimerisk transformerende vekstfaktor-beta.

Info

Publication number
NO895028D0
NO895028D0 NO895028A NO895028A NO895028D0 NO 895028 D0 NO895028 D0 NO 895028D0 NO 895028 A NO895028 A NO 895028A NO 895028 A NO895028 A NO 895028A NO 895028 D0 NO895028 D0 NO 895028D0
Authority
NO
Norway
Prior art keywords
growth factor
transforming growth
factor beta
new chemical
amino acid
Prior art date
Application number
NO895028A
Other languages
English (en)
Other versions
NO300464B1 (no
NO895028L (no
Inventor
Anthony F Purchio
Linda Madisen
Original Assignee
Oncogen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oncogen filed Critical Oncogen
Publication of NO895028D0 publication Critical patent/NO895028D0/no
Publication of NO895028L publication Critical patent/NO895028L/no
Publication of NO300464B1 publication Critical patent/NO300464B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/495—Transforming growth factor [TGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Jellies, Jams, And Syrups (AREA)
NO895028A 1988-12-15 1989-12-14 Nukleotidsekvens som koder for chimerisk transformerende vekstfaktor <beta>1/<beta>2, celle og fremgangsmåte for fremstilling av terapeutisk aktiv chimerisk transformerende vekstfaktor <beta>1/<beta>2 NO300464B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28497288A 1988-12-15 1988-12-15

Publications (3)

Publication Number Publication Date
NO895028D0 true NO895028D0 (no) 1989-12-14
NO895028L NO895028L (no) 1990-06-18
NO300464B1 NO300464B1 (no) 1997-06-02

Family

ID=23092228

Family Applications (1)

Application Number Title Priority Date Filing Date
NO895028A NO300464B1 (no) 1988-12-15 1989-12-14 Nukleotidsekvens som koder for chimerisk transformerende vekstfaktor <beta>1/<beta>2, celle og fremgangsmåte for fremstilling av terapeutisk aktiv chimerisk transformerende vekstfaktor <beta>1/<beta>2

Country Status (18)

Country Link
US (1) US5244793A (no)
EP (1) EP0374044B1 (no)
JP (1) JPH0335794A (no)
KR (1) KR900009983A (no)
CN (1) CN1045994A (no)
AT (1) ATE111520T1 (no)
AU (1) AU634733B2 (no)
CA (1) CA2005120A1 (no)
DE (1) DE68918248T2 (no)
DK (1) DK633389A (no)
ES (1) ES2063834T3 (no)
FI (1) FI97299C (no)
HU (1) HUT52550A (no)
IE (1) IE66571B1 (no)
IL (1) IL92669A (no)
NO (1) NO300464B1 (no)
PT (1) PT92603B (no)
ZA (1) ZA899517B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304541A (en) * 1988-12-15 1994-04-19 Bristol-Myers Squibb Company Methods using novel chimeric transforming growth factor-β1/β2
CA2003886A1 (en) * 1988-12-16 1990-06-16 Anthony F. Purchio Cloning and expression of simian transforming growth factor-beta 1
US5169764A (en) * 1990-08-08 1992-12-08 Regeneron Pharmaceuticals, Inc. Multitrophic and multifunctional chimeric neurotrophic factors, and nucleic acids and plasmids encoding the chimeras
US5206023A (en) * 1991-01-31 1993-04-27 Robert F. Shaw Method and compositions for the treatment and repair of defects or lesions in cartilage
GB9106678D0 (en) * 1991-03-28 1991-05-15 Ferguson Mark W J Wound healing
US5270300A (en) * 1991-09-06 1993-12-14 Robert Francis Shaw Methods and compositions for the treatment and repair of defects or lesions in cartilage or bone
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
AU2738392A (en) * 1991-11-11 1993-05-13 Ciba-Geigy Ag Novel hybrid transforming growth factors
IT1259042B (it) * 1992-01-27 1996-03-11 Mini Ricerca Scient Tecnolog Preparazione di vettori di espressione per la sintesi del polipeptide chiamato fattore osteogenetico op-1 in cellule eucariotiche di spodoptera frugiperda via infezione con baculovirus ricombinante
US6395494B1 (en) 1993-05-13 2002-05-28 Neorx Corporation Method to determine TGF-β
US5420243A (en) * 1993-01-26 1995-05-30 Celtrix Pharmaceuticals, Inc. Biologically active TGF-β2 peptides
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
JPH08510451A (ja) * 1993-05-13 1996-11-05 ネオルックス コーポレイション 異常増殖性平滑筋細胞に関連した病因の予防及び治療
AU6959898A (en) 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
JP4033400B2 (ja) * 2002-03-12 2008-01-16 ティシュージーン，インク 軟骨細胞とＴＧＦ−βを用いた軟骨再生

Also Published As

Publication number Publication date
EP0374044B1 (en) 1994-09-14
NO300464B1 (no) 1997-06-02
AU4683489A (en) 1990-06-21
IE66571B1 (en) 1996-01-24
ZA899517B (en) 1990-09-26
IL92669A0 (en) 1990-08-31
DE68918248D1 (de) 1994-10-20
CN1045994A (zh) 1990-10-10
PT92603A (pt) 1990-06-29
FI97299C (fi) 1996-11-25
IE893984L (en) 1990-06-15
NO895028L (no) 1990-06-18
KR900009983A (ko) 1990-07-06
US5244793A (en) 1993-09-14
HU896613D0 (en) 1990-02-28
CA2005120A1 (en) 1990-06-15
EP0374044A2 (en) 1990-06-20
DE68918248T2 (de) 1995-05-04
PT92603B (pt) 1995-09-12
ATE111520T1 (de) 1994-09-15
HUT52550A (en) 1990-07-28
ES2063834T3 (es) 1995-01-16
JPH0335794A (ja) 1991-02-15
IL92669A (en) 1997-02-18
FI97299B (fi) 1996-08-15
DK633389A (da) 1990-06-16
AU634733B2 (en) 1993-03-04
EP0374044A3 (en) 1991-07-31
FI895935A0 (fi) 1989-12-12
DK633389D0 (da) 1989-12-14

Similar Documents

Publication Publication Date Title
NO895028L (no) Ny chimerisk transformerende vekstfaktor-beta.
DE68929510D1 (de) Nukleotidsequenzen, die für ein Protein mit Ureaseaktivität kodieren
FI895346A0 (fi) Bindande proteiner.
ATE364703T1 (de) Herstellung von proteinen aus pro-proteinen durch fusionsproteine abgeleitet von furin oder furinanalogen
DE3855449D1 (de) DNS-Klone von menschlichem Thrombomodulin
FI90667C (fi) Menetelmä valmistaa uutta ihmisen tyypin I interferoniproteiinia
ATE120494T1 (de) Fibronectinbindungsprotein und dessen herstellung.
ES2055149T3 (es) Derivado de hirudina.
DK38889D0 (da) Onkogen-indkodet polypeptid med vaekstfaktoraktivitet
DE59409964D1 (de) Rekombinante D-Hydantoinase, Verfahren zur Herstellung und Verwendung
ATE166231T1 (de) Produktion und verwendung von antihelmintischen substanzen und schützenden immunogenen
ATE109827T1 (de) Verfahren zur herstellung von peptiden, dazu zu verwendendes rekombinantes plasmid und mit diesem plasmid transformierte myelomzellen.
ATE199397T1 (de) Multiple virus-resistenz aufweisende transgene pflanzen und verfahren zu ihrer herstellung
DE59108261D1 (de) Peptide des HIV-gag Proteins, ihre Herstellung und Verwendung
GR3001086T3 (en) Substituted dioxanones, method for preparing same and use thereof
DE60138885D1 (de) Polypeptide mit aktivität der stimulierung von neutrophilen