NO883392L - Fremgangsmaate ved fremstilling av tiometyl- og sulfinylmetylderivater. - Google Patents

Fremgangsmaate ved fremstilling av tiometyl- og sulfinylmetylderivater.

Info

Publication number
NO883392L
NO883392L NO88883392A NO883392A NO883392L NO 883392 L NO883392 L NO 883392L NO 88883392 A NO88883392 A NO 88883392A NO 883392 A NO883392 A NO 883392A NO 883392 L NO883392 L NO 883392L
Authority
NO
Norway
Prior art keywords
sulphinylmethyl
thiomethyl
derivatives
procedure
preparation
Prior art date
Application number
NO88883392A
Other languages
English (en)
Other versions
NO172489C (no
NO883392D0 (no
NO172489B (no
Inventor
Paolo Chiesi
Vittorino Servadio
Roberta Razzetti
Original Assignee
Chiesi Farma Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farma Spa filed Critical Chiesi Farma Spa
Publication of NO883392D0 publication Critical patent/NO883392D0/no
Publication of NO883392L publication Critical patent/NO883392L/no
Publication of NO172489B publication Critical patent/NO172489B/no
Publication of NO172489C publication Critical patent/NO172489C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36Sulfur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/26Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36Sulfur atom
    • C07D473/38Sulfur atom attached in position 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO883392A 1987-07-31 1988-07-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktive imidazolderivater NO172489C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21538/87A IT1222412B (it) 1987-07-31 1987-07-31 Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono

Publications (4)

Publication Number Publication Date
NO883392D0 NO883392D0 (no) 1988-07-29
NO883392L true NO883392L (no) 1989-02-01
NO172489B NO172489B (no) 1993-04-19
NO172489C NO172489C (no) 1993-07-28

Family

ID=11183290

Family Applications (1)

Application Number Title Priority Date Filing Date
NO883392A NO172489C (no) 1987-07-31 1988-07-29 Analogifremgangsmaate ved fremstilling av terapeutisk aktive imidazolderivater

Country Status (13)

Country Link
US (2) US5049566A (no)
EP (1) EP0301422A3 (no)
JP (1) JPS6463575A (no)
KR (1) KR890002115A (no)
AU (1) AU615933B2 (no)
DK (1) DK427288A (no)
FI (1) FI883511A (no)
HU (1) HU201058B (no)
IT (1) IT1222412B (no)
NO (1) NO172489C (no)
NZ (1) NZ225629A (no)
PT (1) PT88141A (no)
ZA (1) ZA885585B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
AU622866B2 (en) * 1987-07-21 1992-04-30 Hoechst Aktiengesellschaft Substituted thienoimidazole derivatives, processes for their preparation, pharmaceutical formulations containing them and their use as gastric acid secretion inhibitors
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono
JPS6440467A (en) * 1987-08-04 1989-02-10 Hisamitsu Pharmaceutical Co Novel substituted diphenylimidazole derivative
JP2582406B2 (ja) * 1988-04-11 1997-02-19 日清製粉株式会社 新規なキノキサリン誘導体及びそれを含有する坑潰瘍剤
JP2614756B2 (ja) * 1988-08-10 1997-05-28 日本ケミファ株式会社 イミダゾール誘導体およびその製造法ならびにこれを含有する抗潰瘍剤
JP2679745B2 (ja) * 1989-06-29 1997-11-19 明治製菓株式会社 アゾール誘導体及びそれらを有効成分とする抗潰瘍剤
ATE102610T1 (de) * 1989-08-10 1994-03-15 Nippon Chemiphar Co Imidazolderivate, verfahren zu deren herstellung und diese enthaltende antiulkusmittel.
JP2933739B2 (ja) * 1990-04-09 1999-08-16 明治製菓株式会社 チアゾールまたはイミダゾール誘導体および抗潰瘍剤
JPH0770083A (ja) * 1993-07-05 1995-03-14 Nippon Chemiphar Co Ltd イミダゾール誘導体を有効成分とする血圧降下剤
JP3046924B2 (ja) * 1995-03-27 2000-05-29 株式会社アラクス イミダゾリン誘導体又はそれらの可能な互変異性体及びそれらの製造方法並びにそれらを有効成分とする創傷治療薬
FR2751649B1 (fr) * 1996-07-26 1998-08-28 Adir Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US6159968A (en) * 1998-01-15 2000-12-12 University Of Cincinnati Activation of chloride channels for correction of defective chloride transport
JP5911476B2 (ja) * 2010-05-26 2016-04-27 スノビオン プハルマセウトイカルス インコーポレイテッド ヘテロアリール化合物及びその使用方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2580475A (en) * 1947-10-30 1952-01-01 Schering Corp Imidazolinylalkyl ethers of pyridylcarbinols
US3238207A (en) * 1960-03-01 1966-03-01 Burroughs Wellcome Co 6-oxyorganopurines and method of preparing them
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
GB2038825B (en) * 1978-12-16 1983-02-09 Wyeth John & Brother Ltd Heterocyclic compounds substituted by heterocyclyl-alkyl-thio groups
US4330552A (en) * 1980-11-06 1982-05-18 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-arylthioimidazoles
AU4640985A (en) * 1984-08-31 1986-03-06 Nippon Chemiphar Co. Ltd. Benzimidazole derivatives
EP0187977B1 (en) * 1984-12-18 1990-08-29 Otsuka Pharmaceutical Co., Ltd. Tetrahydroquinoline derivatives, process for preparing the same and anti-peptic ulcer compositions containg the same
FI861772A (fi) * 1985-05-07 1986-11-08 Chemie Linz Ag Nya tieno(2,3-d)imidazolderivat och foerfarande for deras framstaellning.
AR243167A1 (es) * 1985-08-24 1993-07-30 Hoechst Ag Procedimiento para la preparacion de toluidinas sustituidas.
KR950001015B1 (ko) * 1986-01-10 1995-02-07 닛뽕 케미화 가부시끼가이샤 술폭시드 유도체의 제조방법
ES2032394T3 (es) * 1986-02-20 1993-02-16 Hoechst Aktiengesellschaft Procedimiento para preparar derivados de tienoimidazol sustituidos.
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
JPH0643426B2 (ja) * 1986-07-25 1994-06-08 東京田辺製薬株式会社 イミダゾ〔4,5−b〕ピリジン誘導体、その製造法及びそれを含有する抗潰瘍剤
DE3639926A1 (de) * 1986-11-22 1988-06-01 Hoechst Ag Substituierte thienoimidazoltoluidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer
DE3723327A1 (de) * 1987-07-15 1989-02-02 Hoechst Ag Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
IT1222412B (it) * 1987-07-31 1990-09-05 Chiesi Farma Spa Tiometil e sulfinil metil derivati ad azione antisecretiva acida gastrica,loro procedimento di preparazione e composizioni farmaceutiche che li contengono

Also Published As

Publication number Publication date
US5066652A (en) 1991-11-19
AU2022888A (en) 1989-02-02
FI883511A0 (fi) 1988-07-26
IT8721538A0 (it) 1987-07-31
NZ225629A (en) 1991-01-29
EP0301422A3 (en) 1990-03-28
KR890002115A (ko) 1989-04-07
EP0301422A2 (en) 1989-02-01
ZA885585B (en) 1989-04-26
NO172489C (no) 1993-07-28
NO883392D0 (no) 1988-07-29
PT88141A (pt) 1989-06-30
JPS6463575A (en) 1989-03-09
HUT47930A (en) 1989-04-28
HU201058B (en) 1990-09-28
DK427288D0 (da) 1988-07-29
IT1222412B (it) 1990-09-05
FI883511A (fi) 1989-02-01
NO172489B (no) 1993-04-19
AU615933B2 (en) 1991-10-17
DK427288A (da) 1989-02-01
US5049566A (en) 1991-09-17

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