NO864993D0 - 2-((3,5-dihalo-4-aminobenzyl))imidazoliner. - Google Patents
2-((3,5-dihalo-4-aminobenzyl))imidazoliner.Info
- Publication number
- NO864993D0 NO864993D0 NO864993A NO864993A NO864993D0 NO 864993 D0 NO864993 D0 NO 864993D0 NO 864993 A NO864993 A NO 864993A NO 864993 A NO864993 A NO 864993A NO 864993 D0 NO864993 D0 NO 864993D0
- Authority
- NO
- Norway
- Prior art keywords
- aminobenzyl
- dihalo
- imidazoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/807,921 US4665095A (en) | 1985-12-11 | 1985-12-11 | Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion |
Publications (2)
Publication Number | Publication Date |
---|---|
NO864993D0 true NO864993D0 (no) | 1986-12-10 |
NO864993L NO864993L (no) | 1987-06-12 |
Family
ID=25197433
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO864993A NO864993L (no) | 1985-12-11 | 1986-12-10 | 2-((3,5-dihalo-4-aminobenzyl))imidazoliner. |
Country Status (9)
Country | Link |
---|---|
US (1) | US4665095A (no) |
EP (1) | EP0230532B1 (no) |
JP (1) | JPH07116038B2 (no) |
AU (1) | AU591740B2 (no) |
CA (1) | CA1282334C (no) |
DE (1) | DE3674569D1 (no) |
FI (1) | FI865025A (no) |
NO (1) | NO864993L (no) |
NZ (1) | NZ218334A (no) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5114979A (en) * | 1989-10-18 | 1992-05-19 | Schering Corporation | Fruity flavored nasal decongestant composition |
US4970240A (en) * | 1989-10-18 | 1990-11-13 | Schering Corporation | Fruity flavored nasal decongestant composition |
JP4096363B2 (ja) * | 1997-03-14 | 2008-06-04 | 日本新薬株式会社 | 鼻又は眼の充血治療剤 |
SG72827A1 (en) * | 1997-06-23 | 2000-05-23 | Hoffmann La Roche | Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives |
AU3883099A (en) * | 1998-05-06 | 1999-11-23 | Duke University | Method of treating bladder and lower urinary tract syndromes |
RU2008130455A (ru) * | 2006-01-27 | 2010-03-10 | Ф.Хоффманн-Ля Рош Аг (Ch) | Применение замещенных производных 2-имидазола или имидазолинов |
AU2007312389B2 (en) * | 2006-10-19 | 2012-02-23 | F. Hoffmann-La Roche Ag | Aminomethyl-2-imidazoles with affinity with the trace amine associated receptors |
CN101528710B (zh) * | 2006-10-19 | 2012-11-07 | 弗·哈夫曼-拉罗切有限公司 | 氨基甲基-4-咪唑类 |
EP2086959B1 (en) * | 2006-11-02 | 2011-11-16 | F. Hoffmann-La Roche AG | Substituted 2-imidazoles as modulators of the trace amine associated receptors |
CN101535298A (zh) * | 2006-11-16 | 2009-09-16 | 弗·哈夫曼-拉罗切有限公司 | 取代的4-咪唑类化合物 |
CN101557810B (zh) * | 2006-12-13 | 2012-11-21 | 弗·哈夫曼-拉罗切有限公司 | 作为痕量胺相关受体(taar)的配体的新的2-咪唑类 |
US20080146523A1 (en) | 2006-12-18 | 2008-06-19 | Guido Galley | Imidazole derivatives |
UA98951C2 (ru) | 2007-02-02 | 2012-07-10 | Ф. Хоффманн-Ля Рош Аг | 2-аминооксазолины и лекарственное средство, которое их содержит |
KR101222412B1 (ko) * | 2007-02-15 | 2013-01-15 | 에프. 호프만-라 로슈 아게 | Taar1 리간드로서의 2-아미노옥사졸린 |
AU2008270445A1 (en) | 2007-07-02 | 2009-01-08 | F. Hoffmann-La Roche Ag | 2 -imidazolines having a good affinity to the trace amine associated receptors (TAARs) |
WO2009003867A1 (en) * | 2007-07-03 | 2009-01-08 | F. Hoffmann-La Roche Ag | 4-imidazolines and their use as antidepressants |
CA2694362A1 (en) * | 2007-07-27 | 2009-02-05 | F. Hoffmann-La Roche Ag | 2-azetidinemethaneamines and 2-pyrrolidinemethaneamines as taar-ligands |
JP2010535172A (ja) * | 2007-08-02 | 2010-11-18 | エフ.ホフマン−ラ ロシュ アーゲー | Cns障害の処置のためのベンズアミド誘導体の使用 |
JP5341084B2 (ja) * | 2007-08-03 | 2013-11-13 | エフ.ホフマン−ラ ロシュ アーゲー | Taar1リガンドとしてのピリジンカルボキシアミド及びベンズアミド誘導体 |
US9381166B2 (en) * | 2007-10-02 | 2016-07-05 | Rigshospitalet | Systemic pro-hemostatic effect of sympathicomimetics with agonistic effects on alfa-adrenergic and/or beta-adrenergic receptors of the sympathetic nervous system, related to improved clot strength |
BRPI0916363A2 (pt) * | 2008-07-24 | 2018-05-29 | Hoffmann La Roche | derivados de 4,5-di-hidro-oxazol-2-ila |
US8242153B2 (en) * | 2008-07-24 | 2012-08-14 | Hoffmann-La Roche Inc. | 4,5-dihydro-oxazol-2YL derivatives |
US20100311798A1 (en) * | 2009-06-05 | 2010-12-09 | Decoret Guillaume | 2-aminooxazolines as taar1 ligands |
US8354441B2 (en) * | 2009-11-11 | 2013-01-15 | Hoffmann-La Roche Inc. | Oxazoline derivatives |
US9452980B2 (en) | 2009-12-22 | 2016-09-27 | Hoffmann-La Roche Inc. | Substituted benzamides |
MY195528A (en) | 2016-03-17 | 2023-01-30 | Hoffmann La Roche | 5-Ethyl-4-Methyl-Pyrazole-3-Carboxamide Derivative Having Activity as Agonist of Taar |
CN110944689B (zh) | 2017-06-07 | 2022-12-09 | 施菲姆德控股有限责任公司 | 血管内流体运动设备、系统和使用方法 |
CN111556763B (zh) | 2017-11-13 | 2023-09-01 | 施菲姆德控股有限责任公司 | 血管内流体运动装置、系统 |
EP3746149A4 (en) | 2018-02-01 | 2021-10-27 | Shifamed Holdings, LLC | INTRAVASCULAR BLOOD PUMPS AND METHODS OF USE AND METHODS OF MANUFACTURING |
US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
EP4034192A4 (en) | 2019-09-25 | 2023-11-29 | Shifamed Holdings, LLC | INTRAVASCULAR BLOOD PUMP SYSTEMS AND METHODS OF USE AND CONTROL THEREOF |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2731471A (en) * | 1956-01-17 | Nxg hi | ||
US2868802A (en) * | 1959-01-13 | Nxchj | ||
DE1617618B2 (de) * | 1966-06-18 | 1976-05-20 | Merck Patent Gmbh, 6100 Darmstadt | Schleimhautabschwellende mittel zur lokalen applikation |
DE1618005A1 (de) * | 1966-09-22 | 1971-09-09 | Thomae Gmbh Dr K | Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen |
US3660423A (en) * | 1970-02-13 | 1972-05-02 | Dow Chemical Co | 2-(substituted benzyl)methyl-2-imidazolines |
US3922282A (en) * | 1975-01-17 | 1975-11-25 | American Home Prod | 2-Aryl-2-imidazoline-1-propionic acids and their esters |
AU1623483A (en) * | 1978-02-01 | 1983-10-13 | Wellcome Foundation Limited, The | Formulations of imidazole derivatives |
US4506074A (en) * | 1982-11-08 | 1985-03-19 | Merck & Co., Inc. | 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and derivatives |
US4461914A (en) * | 1983-02-01 | 1984-07-24 | American Cyanamid Company | Method for the preparation of 1-(4'-amino-3',5'-dichlorophenyl)-2-alkyl(or dialkyl)aminoethanols |
FR2549049B1 (fr) * | 1983-07-13 | 1986-06-20 | Chauvin Blache Lab | Nouvelles amidines, leur procede de preparation et leur application therapeutique |
-
1985
- 1985-12-11 US US06/807,921 patent/US4665095A/en not_active Expired - Fee Related
-
1986
- 1986-10-30 EP EP86115057A patent/EP0230532B1/en not_active Expired - Lifetime
- 1986-10-30 DE DE8686115057T patent/DE3674569D1/de not_active Expired - Fee Related
- 1986-11-19 NZ NZ218334A patent/NZ218334A/xx unknown
- 1986-11-28 JP JP61282192A patent/JPH07116038B2/ja not_active Expired - Lifetime
- 1986-12-02 CA CA000524368A patent/CA1282334C/en not_active Expired - Fee Related
- 1986-12-09 AU AU66319/86A patent/AU591740B2/en not_active Ceased
- 1986-12-10 NO NO864993A patent/NO864993L/no unknown
- 1986-12-10 FI FI865025A patent/FI865025A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
FI865025A (fi) | 1987-06-12 |
NO864993L (no) | 1987-06-12 |
CA1282334C (en) | 1991-04-02 |
AU6631986A (en) | 1987-06-18 |
AU591740B2 (en) | 1989-12-14 |
NZ218334A (en) | 1989-03-29 |
JPS62145067A (ja) | 1987-06-29 |
EP0230532B1 (en) | 1990-09-26 |
EP0230532A1 (en) | 1987-08-05 |
FI865025A0 (fi) | 1986-12-10 |
JPH07116038B2 (ja) | 1995-12-13 |
US4665095A (en) | 1987-05-12 |
DE3674569D1 (de) | 1990-10-31 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO864993D0 (no) | 2-((3,5-dihalo-4-aminobenzyl))imidazoliner. | |
DE3577547D1 (de) | 2-(2'-nitrobenzoyl)-1,3-cyclohexandionen. | |
FI861210A0 (fi) | N,n'-dialkylguanidinodipeptider. | |
FI853193L (fi) | Smaertstillande 1,2-benzisotiazol-3 -ylpiperazinderivat. | |
ATE38827T1 (de) | Bestimmte 2-(2'-alkylbenzoyl)-1,3cyclohexandione. | |
DE3669876D1 (de) | 3,4-dihydrobenzopyranderivate. | |
DE3775802D1 (de) | 2-(4'-alkoxyphenyl)-5-alkylpyridine. | |
NL971040I2 (nl) | 1-Dimethylcarbamoyl-3-gesubstitueerde-5-gesubstitueerde-1H-1,2,4-triazolen. | |
ATE45741T1 (de) | 1-oxa-3-oxo-4,8-diaza-spiro-(4,5>decanverbindungen. | |
IT8521944A0 (it) | 1,4-diidropiridine-2-sostituite. | |
DE3674054D1 (de) | 1,3-disubstituierte imidazoliumsalze. | |
DE3585315D1 (de) | 5,6,7,8-tetrafluoranthrachinonderivate. | |
DE3586745T2 (de) | 9,11-epoxy-21-hydroxypregnan-derivate. | |
FI863300A0 (fi) | 7-oxo-4-tia-1-azabicyclo/3,2,0/ hept-2-enderivat. | |
FI861950A0 (fi) | 1,3-dioxan-etrar. | |
DE3684900D1 (de) | 2,2'-bi-1h-imidazole. | |
FI853421L (fi) | 7-oxo-4-tia-1-azabicyklo/3,2,0/ hept-2-enderivat. | |
FI865158A0 (fi) | 1-h-pyrido/3,2//1,4/-tiaziner. | |
DE3586541T2 (de) | 1,3-dithiol-2-ylidenderivate. | |
IT8620495A0 (it) | 2,4-dicloro-5-nitro-tiazolo. | |
DE3674284D1 (de) | Kationische 1,2,3-thiadiazolazoverbindungen. | |
ATE61586T1 (de) | 2-(arylbenzothiazin)-derivate. | |
DE3678154D1 (de) | 2-(arylbenzothiazin)-derivate. | |
ATE45349T1 (de) | Substituierte 2,3,4,9-tetrahydro-1h-carbazol-1essigs|urederivate. | |
NO892008L (no) | Substituert 1,2,4-oksadiazol. |