NO864993D0 - 2-((3,5-dihalo-4-aminobenzyl))imidazoliner. - Google Patents

2-((3,5-dihalo-4-aminobenzyl))imidazoliner.

Info

Publication number
NO864993D0
NO864993D0 NO864993A NO864993A NO864993D0 NO 864993 D0 NO864993 D0 NO 864993D0 NO 864993 A NO864993 A NO 864993A NO 864993 A NO864993 A NO 864993A NO 864993 D0 NO864993 D0 NO 864993D0
Authority
NO
Norway
Prior art keywords
aminobenzyl
dihalo
imidazoline
Prior art date
Application number
NO864993A
Other languages
English (en)
Other versions
NO864993L (no
Inventor
Martin Winn
John Francis Debernardis
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of NO864993D0 publication Critical patent/NO864993D0/no
Publication of NO864993L publication Critical patent/NO864993L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/24—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicinal Preparation (AREA)
NO864993A 1985-12-11 1986-12-10 2-((3,5-dihalo-4-aminobenzyl))imidazoliner. NO864993L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/807,921 US4665095A (en) 1985-12-11 1985-12-11 Use of 2-[(3,5-dihalo-4-aminobenzyl)]imidazolines to stimulate alpha-1 adrenergic receptors and to treat nasal congestion

Publications (2)

Publication Number Publication Date
NO864993D0 true NO864993D0 (no) 1986-12-10
NO864993L NO864993L (no) 1987-06-12

Family

ID=25197433

Family Applications (1)

Application Number Title Priority Date Filing Date
NO864993A NO864993L (no) 1985-12-11 1986-12-10 2-((3,5-dihalo-4-aminobenzyl))imidazoliner.

Country Status (9)

Country Link
US (1) US4665095A (no)
EP (1) EP0230532B1 (no)
JP (1) JPH07116038B2 (no)
AU (1) AU591740B2 (no)
CA (1) CA1282334C (no)
DE (1) DE3674569D1 (no)
FI (1) FI865025A (no)
NO (1) NO864993L (no)
NZ (1) NZ218334A (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5114979A (en) * 1989-10-18 1992-05-19 Schering Corporation Fruity flavored nasal decongestant composition
US4970240A (en) * 1989-10-18 1990-11-13 Schering Corporation Fruity flavored nasal decongestant composition
WO1998041199A1 (fr) * 1997-03-14 1998-09-24 Nippon Shinyaku Co., Ltd. Decongestionnant nasal ou oculaire
SG72827A1 (en) * 1997-06-23 2000-05-23 Hoffmann La Roche Phenyl-and aminophenyl-alkylsulfonamide and urea derivatives
AU3883099A (en) * 1998-05-06 1999-11-23 Duke University Method of treating bladder and lower urinary tract syndromes
KR20080080410A (ko) * 2006-01-27 2008-09-03 에프. 호프만-라 로슈 아게 이미다졸린 유도체의 치환된 2-이미다졸의 용도
AU2007312390B2 (en) * 2006-10-19 2013-03-28 F. Hoffmann-La Roche Ag Aminomethyl-4-imidazoles
KR101172940B1 (ko) * 2006-10-19 2012-08-10 에프. 호프만-라 로슈 아게 트레이스 아민 관련 수용체에 대해 친화도를 갖는 아미노메틸-2-이미다졸
JP5064511B2 (ja) * 2006-11-02 2012-10-31 エフ．ホフマン−ラ ロシュ アーゲー 痕跡アミン関連受容体調節剤としての置換２−イミダゾール
KR101134226B1 (ko) * 2006-11-16 2012-04-10 에프. 호프만-라 로슈 아게 치환된 4-이미다졸
WO2008071574A1 (en) * 2006-12-13 2008-06-19 F. Hoffmann-La Roche Ag Novel 2 -imidazoles as ligands for trace amine associated receptors (taar)
US20080146523A1 (en) 2006-12-18 2008-06-19 Guido Galley Imidazole derivatives
JP5248528B2 (ja) 2007-02-02 2013-07-31 エフ．ホフマン−ラ ロシュ アーゲー Ｃｎｓ疾患用のｔａａｒ１リガンドとしての新規２−アミノオキサゾリン
CA2676944C (en) * 2007-02-15 2016-01-19 F. Hoffmann-La Roche Ag 2-aminooxazolines as taar1 ligands
EP2173720A2 (en) 2007-07-02 2010-04-14 F. Hoffmann-Roche AG 2-imidazolines having a good affinity to the trace amine associated receptors (taars)
BRPI0812833A2 (pt) * 2007-07-03 2014-12-09 Hoffmann La Roche 4-imidazolinas e seu uso como antidepressivos
KR101133862B1 (ko) * 2007-07-27 2012-04-06 에프. 호프만-라 로슈 아게 Ｔａａｒ 리간드로서의 2-아제티딘메테인아민 및 2-피롤리딘메테인아민
JP2010535172A (ja) * 2007-08-02 2010-11-18 エフ．ホフマン−ラ ロシュ アーゲー Ｃｎｓ障害の処置のためのベンズアミド誘導体の使用
AU2008285795A1 (en) * 2007-08-03 2009-02-12 F. Hoffmann-La Roche Ag Pyridinecarboxamide and benzamide derivatives as TAAR1 ligands
CA2701555A1 (en) * 2007-10-02 2009-04-09 Hemostasis Holding Aps Systemic pro-hemostatic effect of sympathicomimetics with agonistic effects on .alpha.-adrenergic and/or .beta.-adrenergic receptors of the sympathetic nervous system, related to improved clot strength
US8242153B2 (en) * 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
CN102083805A (zh) * 2008-07-24 2011-06-01 弗·哈夫曼-拉罗切有限公司 4,5-二氢-唑-2-基衍生物
US20100311798A1 (en) * 2009-06-05 2010-12-09 Decoret Guillaume 2-aminooxazolines as taar1 ligands
US8354441B2 (en) * 2009-11-11 2013-01-15 Hoffmann-La Roche Inc. Oxazoline derivatives
US9452980B2 (en) 2009-12-22 2016-09-27 Hoffmann-La Roche Inc. Substituted benzamides
SG11201807516UA (en) 2016-03-17 2018-09-27 Hoffmann La Roche 5-ethyl-4-methyl-pyrazole-3-carboxamide derivative having activity as agonist of taar
WO2018226991A1 (en) 2017-06-07 2018-12-13 Shifamed Holdings, Llc Intravascular fluid movement devices, systems, and methods of use
CN111556763B (zh) 2017-11-13 2023-09-01 施菲姆德控股有限责任公司 血管内流体运动装置、系统
EP4085965A1 (en) 2018-02-01 2022-11-09 Shifamed Holdings, LLC Intravascular blood pumps and methods of use and manufacture
JP2022540616A (ja) 2019-07-12 2022-09-16 シファメド・ホールディングス・エルエルシー 血管内血液ポンプならびに製造および使用の方法
US11654275B2 (en) 2019-07-22 2023-05-23 Shifamed Holdings, Llc Intravascular blood pumps with struts and methods of use and manufacture
WO2021062270A1 (en) 2019-09-25 2021-04-01 Shifamed Holdings, Llc Catheter blood pumps and collapsible pump housings
EP4034192A4 (en) 2019-09-25 2023-11-29 Shifamed Holdings, LLC INTRAVASCULAR BLOOD PUMP SYSTEMS AND METHODS OF USE AND CONTROL THEREOF

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2868802A (en) * 1959-01-13 Nxchj
US2731471A (en) * 1956-01-17 Nxg hi
DE1617618B2 (de) * 1966-06-18 1976-05-20 Merck Patent Gmbh, 6100 Darmstadt Schleimhautabschwellende mittel zur lokalen applikation
DE1618005A1 (de) * 1966-09-22 1971-09-09 Thomae Gmbh Dr K Verfahren zur Herstellung von neuen Amino-dihalogen-phenyl-aethylaminen
US3660423A (en) * 1970-02-13 1972-05-02 Dow Chemical Co 2-(substituted benzyl)methyl-2-imidazolines
US3922282A (en) * 1975-01-17 1975-11-25 American Home Prod 2-Aryl-2-imidazoline-1-propionic acids and their esters
AU1623483A (en) * 1978-02-01 1983-10-13 Wellcome Foundation Limited, The Formulations of imidazole derivatives
US4506074A (en) * 1982-11-08 1985-03-19 Merck & Co., Inc. 2-[2-Pyridinyloxy(thio or amino)methyl]-1H-imidazoles and derivatives
US4461914A (en) * 1983-02-01 1984-07-24 American Cyanamid Company Method for the preparation of 1-(4'-amino-3',5'-dichlorophenyl)-2-alkyl(or dialkyl)aminoethanols
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique

Also Published As

Publication number Publication date
US4665095A (en) 1987-05-12
NZ218334A (en) 1989-03-29
DE3674569D1 (de) 1990-10-31
JPS62145067A (ja) 1987-06-29
NO864993L (no) 1987-06-12
AU591740B2 (en) 1989-12-14
EP0230532B1 (en) 1990-09-26
FI865025A0 (fi) 1986-12-10
AU6631986A (en) 1987-06-18
CA1282334C (en) 1991-04-02
EP0230532A1 (en) 1987-08-05
JPH07116038B2 (ja) 1995-12-13
FI865025A (fi) 1987-06-12

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