NO850769L - Nukleinsyre-protein konjugat - Google Patents
Nukleinsyre-protein konjugatInfo
- Publication number
- NO850769L NO850769L NO850769A NO850769A NO850769L NO 850769 L NO850769 L NO 850769L NO 850769 A NO850769 A NO 850769A NO 850769 A NO850769 A NO 850769A NO 850769 L NO850769 L NO 850769L
- Authority
- NO
- Norway
- Prior art keywords
- nucleic acid
- protein
- linked
- labeled
- label
- Prior art date
Links
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- GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 description 1
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- LOKCTEFSRHRXRJ-UHFFFAOYSA-I dipotassium trisodium dihydrogen phosphate hydrogen phosphate dichloride Chemical compound P(=O)(O)(O)[O-].[K+].P(=O)(O)([O-])[O-].[Na+].[Na+].[Cl-].[K+].[Cl-].[Na+] LOKCTEFSRHRXRJ-UHFFFAOYSA-I 0.000 description 1
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- MIKKOBKEXMRYFQ-WZTVWXICSA-N meglumine amidotrizoate Chemical compound C[NH2+]C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CC(=O)NC1=C(I)C(NC(C)=O)=C(I)C(C([O-])=O)=C1I MIKKOBKEXMRYFQ-WZTVWXICSA-N 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/682—Signal amplification
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/964—Chemistry: molecular biology and microbiology including enzyme-ligand conjugate production, e.g. reducing rate of nonproductive linkage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/828—Protein A
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/588,858 US4748111A (en) | 1984-03-12 | 1984-03-12 | Nucleic acid-protein conjugate used in immunoassay |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO850769L true NO850769L (no) | 1985-09-13 |
Family
ID=24355587
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO850769A NO850769L (no) | 1984-03-12 | 1985-02-26 | Nukleinsyre-protein konjugat |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4748111A (ja) |
| EP (1) | EP0154884A3 (ja) |
| JP (1) | JPS60226900A (ja) |
| AU (1) | AU578933B2 (ja) |
| CA (1) | CA1222706A (ja) |
| DK (1) | DK110885A (ja) |
| ES (1) | ES8606653A1 (ja) |
| FI (1) | FI850925L (ja) |
| IL (1) | IL74539A (ja) |
| NO (1) | NO850769L (ja) |
| NZ (1) | NZ211366A (ja) |
| ZA (1) | ZA851797B (ja) |
Families Citing this family (67)
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| US4957858A (en) * | 1986-04-16 | 1990-09-18 | The Salk Instute For Biological Studies | Replicative RNA reporter systems |
| US4925785A (en) * | 1986-03-07 | 1990-05-15 | Biotechnica Diagnostics, Inc. | Nucleic acid hybridization assays |
| US5384241A (en) * | 1987-09-11 | 1995-01-24 | Enzo Diagnostics, Inc. | Specific binding assay compound with inhibitive self-quenching characteristics |
| DE3732145A1 (de) * | 1987-09-24 | 1989-04-06 | Merck Patent Gmbh | Verfahren und reagenz zur durchfuehrung von hybridisierungsreaktionen |
| US5428132A (en) * | 1987-10-11 | 1995-06-27 | United States Of America | Conjugate and method for integration of foreign DNA into cells |
| US5656731A (en) * | 1987-10-15 | 1997-08-12 | Chiron Corporation | Nucleic acid-amplified immunoassay probes |
| US5359100A (en) * | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
| US5525465A (en) * | 1987-10-28 | 1996-06-11 | Howard Florey Institute Of Experimental Physiology And Medicine | Oligonucleotide-polyamide conjugates and methods of production and applications of the same |
| WO1989003849A1 (en) * | 1987-10-28 | 1989-05-05 | Howard Florey Institute Of Experimental Physiology | Oligonucleotide-polyamide conjugates |
| US4921788A (en) * | 1988-04-12 | 1990-05-01 | The Research Foundation Of State University Of New York | Competitive nucleic acid immunoassay for the detection of analytes |
| US5109124A (en) * | 1988-06-01 | 1992-04-28 | Biogen, Inc. | Nucleic acid probe linked to a label having a terminal cysteine |
| CA2031659A1 (en) * | 1990-01-26 | 1991-07-27 | John B. Findlay | Water-insoluble reagent, nucleic acid probe, test kit and diagnostic and purification methods |
| US5763162A (en) | 1990-03-14 | 1998-06-09 | The Regents Of University Of California | Multichromophore fluorescent DNA intercalation complexes |
| US5783687A (en) * | 1990-03-14 | 1998-07-21 | The Regents Of The University Of California | Dyes designed for high sensitivity detection of double-stranded DNA |
| JPH05505526A (ja) * | 1990-03-14 | 1993-08-19 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 多発光団蛍光プローブ |
| EP0528870B1 (en) * | 1990-05-04 | 1998-12-02 | Chiron Corporation | Protein-nucleic acid probes and immunoassays using same |
| US5677440A (en) * | 1990-07-16 | 1997-10-14 | Howard Florey Institute Of Experimental Physiology And Medicine | Oligonucleotide-polyamide conjugates |
| EP0488152A3 (en) * | 1990-11-30 | 1992-11-25 | Hitachi, Ltd. | Method for immunoassay and apparatus therefor |
| WO1992014758A1 (en) * | 1991-02-13 | 1992-09-03 | The Austin Research Institute | Conjugate molecules |
| WO1993010461A1 (en) * | 1991-11-12 | 1993-05-27 | Promega Corporation | Non-radioactive enzyme assay |
| JPH05149949A (ja) * | 1991-11-26 | 1993-06-15 | Nisshin Flour Milling Co Ltd | 新規な微量物質測定法 |
| US5747244A (en) * | 1991-12-23 | 1998-05-05 | Chiron Corporation | Nucleic acid probes immobilized on polystyrene surfaces |
| WO1993015760A1 (en) * | 1992-02-11 | 1993-08-19 | U.S. Government, As Represented By The Secretary Of The Army | Dual carrier immunogenic construct |
| US5573905A (en) * | 1992-03-30 | 1996-11-12 | The Scripps Research Institute | Encoded combinatorial chemical libraries |
| US5354658A (en) * | 1993-01-28 | 1994-10-11 | Dennis Wright | Non-radioactive method for detecting a labelled segment and a solution or composition therefor |
| JP3197277B2 (ja) * | 1993-05-10 | 2001-08-13 | 日水製薬株式会社 | 一種類以上の免疫学的配位子の分析方法，その分析試薬およびそのキット |
| GB9404709D0 (en) * | 1994-03-11 | 1994-04-27 | Multilyte Ltd | Binding assay |
| US5876924A (en) * | 1994-06-22 | 1999-03-02 | Mount Sinai School Of Medicine | Nucleic acid amplification method hybridization signal amplification method (HSAM) |
| NZ290810A (en) * | 1994-07-25 | 1998-01-26 | Boehringer Mannheim Gmbh | Oligomer carrier molecules with selectively incorporated marker and hapten groups |
| SE504798C2 (sv) * | 1995-06-16 | 1997-04-28 | Ulf Landegren | Immunanalys och testkit med två reagens som kan tvärbindas om de adsorberats till analyten |
| US5854033A (en) | 1995-11-21 | 1998-12-29 | Yale University | Rolling circle replication reporter systems |
| JP3974941B2 (ja) | 1995-11-21 | 2007-09-12 | イェール ユニバーシティ | 単分子セグメントの増幅および検出 |
| JP3130538B2 (ja) * | 1996-06-10 | 2001-01-31 | 株式会社 分子バイオホトニクス研究所 | 高感度蛍光アッセイ |
| WO1998016636A1 (fr) * | 1996-10-17 | 1998-04-23 | Mitsubishi Chemical Corporation | Molecule permettant d'homologuer un genotype et un phenotype, et utilisation de celle-ci |
| US6225074B1 (en) | 1997-08-18 | 2001-05-01 | Dennis Wright | Direct chloramphenicol acetyl transferase assay |
| EP1098996A1 (en) | 1998-07-20 | 2001-05-16 | Yale University | Method for detecting nucleic acids using target-mediated ligation of bipartite primers |
| CA2342838A1 (en) * | 1998-09-15 | 2000-03-23 | Yale University | Molecular cloning using rolling circle amplification |
| WO2000015849A1 (en) * | 1998-09-15 | 2000-03-23 | Yale University | Artificial long terminal repeat vectors |
| US6203989B1 (en) | 1998-09-30 | 2001-03-20 | Affymetrix, Inc. | Methods and compositions for amplifying detectable signals in specific binding assays |
| US6232068B1 (en) * | 1999-01-22 | 2001-05-15 | Rosetta Inpharmatics, Inc. | Monitoring of gene expression by detecting hybridization to nucleic acid arrays using anti-heteronucleic acid antibodies |
| FR2791141B1 (fr) * | 1999-03-15 | 2001-06-01 | Cis Bio Int | Procede de reduction de l'extinction de fluorescence due au milieu de mesure |
| WO2000072869A1 (en) * | 1999-06-01 | 2000-12-07 | Phylos, Inc. | Methods for producing 5'-nucleic acid-protein conjugates |
| US20060166227A1 (en) * | 2000-06-20 | 2006-07-27 | Stephen Kingsmore | Protein expression profiling |
| US6323009B1 (en) * | 2000-06-28 | 2001-11-27 | Molecular Staging, Inc. | Multiply-primed amplification of nucleic acid sequences |
| DE60130763T2 (de) | 2000-06-30 | 2008-07-17 | Qiagen Gmbh | Signalamplifikation mit "lollipop"-hydridisierungsproben |
| DE10041766A1 (de) * | 2000-08-25 | 2002-03-14 | Friz Biochem Gmbh | Verfahren zur Markierung chemischer Substanzen |
| US6573051B2 (en) * | 2001-03-09 | 2003-06-03 | Molecular Staging, Inc. | Open circle probes with intramolecular stem structures |
| US7553619B2 (en) * | 2002-02-08 | 2009-06-30 | Qiagen Gmbh | Detection method using dissociated rolling circle amplification |
| US20040003559A1 (en) * | 2002-04-24 | 2004-01-08 | Minke Ronald C. | Doors and methods of producing same |
| US9487823B2 (en) | 2002-12-20 | 2016-11-08 | Qiagen Gmbh | Nucleic acid amplification |
| US7955795B2 (en) * | 2003-06-06 | 2011-06-07 | Qiagen Gmbh | Method of whole genome amplification with reduced artifact production |
| US6977153B2 (en) * | 2002-12-31 | 2005-12-20 | Qiagen Gmbh | Rolling circle amplification of RNA |
| US8043834B2 (en) | 2003-03-31 | 2011-10-25 | Qiagen Gmbh | Universal reagents for rolling circle amplification and methods of use |
| US8309303B2 (en) | 2005-04-01 | 2012-11-13 | Qiagen Gmbh | Reverse transcription and amplification of RNA with simultaneous degradation of DNA |
| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| JP2009511019A (ja) * | 2005-10-06 | 2009-03-19 | ルシジェン コーポレイション | 耐熱性ウィルス性ポリメラーゼ及びその使用法 |
| US7811810B2 (en) | 2007-10-25 | 2010-10-12 | Industrial Technology Research Institute | Bioassay system including optical detection apparatuses, and method for detecting biomolecules |
| US7767441B2 (en) * | 2007-10-25 | 2010-08-03 | Industrial Technology Research Institute | Bioassay system including optical detection apparatuses, and method for detecting biomolecules |
| JP2011515656A (ja) * | 2008-02-14 | 2011-05-19 | スリーエム イノベイティブ プロパティズ カンパニー | 微生物を検出する方法及び組成物 |
| JP2011519755A (ja) * | 2008-05-05 | 2011-07-14 | ダウ グローバル テクノロジーズ リミティド ライアビリティ カンパニー | フレキシブルシートのエッジを封入するための改良法 |
| US9778188B2 (en) | 2009-03-11 | 2017-10-03 | Industrial Technology Research Institute | Apparatus and method for detection and discrimination molecular object |
| US9482615B2 (en) * | 2010-03-15 | 2016-11-01 | Industrial Technology Research Institute | Single-molecule detection system and methods |
| US8865078B2 (en) | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
| US8865077B2 (en) | 2010-06-11 | 2014-10-21 | Industrial Technology Research Institute | Apparatus for single-molecule detection |
| JP6791750B2 (ja) | 2013-03-11 | 2020-11-25 | メソ スケール テクノロジーズ エルエルシー | 多重化アッセイを行うための改良された方法 |
| EP3465162A4 (en) * | 2016-06-02 | 2020-03-25 | Ultivue, Inc. | COMPOSITIONS AND METHODS FOR ACCELERATING ANTIBODY EXCHANGE IMAGING |
| CN115060912B (zh) * | 2022-06-23 | 2024-02-02 | 南京浦光生物科技有限公司 | 检测目标抗体的试剂组合、试剂盒、检测系统及检测方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2422956A1 (fr) * | 1978-04-13 | 1979-11-09 | Pasteur Institut | Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede |
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| ES8307897A1 (es) * | 1981-04-13 | 1983-08-01 | Hoechst Co American | Un metodo de determinar la presencia de un antigeno en un medio liquido sospechoso de contenerlo. |
| FR2519005B1 (fr) * | 1981-12-29 | 1985-10-25 | Pasteur Institut | Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn |
| US4469787A (en) * | 1982-05-14 | 1984-09-04 | Mallinckrodt Inc. | Immunoassay involving soluble complex of second antibody and labeled binding protein |
| CA1223831A (en) * | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| US4556643A (en) * | 1982-07-26 | 1985-12-03 | Agracetus | Assay method and probe for polynucleotide sequences |
| GB8306426D0 (en) * | 1983-03-09 | 1983-04-13 | Malcolm A D B | Detecting polynucleotide sequence |
| US4737454A (en) * | 1983-07-14 | 1988-04-12 | Molecular Diagnostics, Inc. | Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays |
| US4587044A (en) * | 1983-09-01 | 1986-05-06 | The Johns Hopkins University | Linkage of proteins to nucleic acids |
-
1984
- 1984-03-12 US US06/588,858 patent/US4748111A/en not_active Expired - Fee Related
- 1984-11-26 CA CA000468604A patent/CA1222706A/en not_active Expired
-
1985
- 1985-02-26 NO NO850769A patent/NO850769L/no unknown
- 1985-02-27 EP EP85102130A patent/EP0154884A3/en not_active Withdrawn
- 1985-03-01 AU AU39434/85A patent/AU578933B2/en not_active Ceased
- 1985-03-07 IL IL74539A patent/IL74539A/xx unknown
- 1985-03-08 ES ES541077A patent/ES8606653A1/es not_active Expired
- 1985-03-08 NZ NZ211366A patent/NZ211366A/en unknown
- 1985-03-08 FI FI850925A patent/FI850925L/fi not_active Application Discontinuation
- 1985-03-11 JP JP60046684A patent/JPS60226900A/ja active Pending
- 1985-03-11 DK DK110885A patent/DK110885A/da not_active Application Discontinuation
- 1985-03-11 ZA ZA851797A patent/ZA851797B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL74539A0 (en) | 1985-06-30 |
| AU578933B2 (en) | 1988-11-10 |
| ZA851797B (en) | 1985-11-27 |
| ES8606653A1 (es) | 1986-04-16 |
| DK110885A (da) | 1985-09-13 |
| CA1222706A (en) | 1987-06-09 |
| ES541077A0 (es) | 1986-04-16 |
| EP0154884A3 (en) | 1988-11-30 |
| IL74539A (en) | 1989-01-31 |
| EP0154884A2 (en) | 1985-09-18 |
| US4748111A (en) | 1988-05-31 |
| DK110885D0 (da) | 1985-03-11 |
| FI850925A0 (fi) | 1985-03-08 |
| AU3943485A (en) | 1985-09-19 |
| JPS60226900A (ja) | 1985-11-12 |
| NZ211366A (en) | 1988-05-30 |
| FI850925L (fi) | 1985-09-13 |
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