NO844836L - Fremgangsmaate ved fremstilling av 2-pyridylmethyl-thio- og -sulfinylbenzimidazoler - Google Patents

Fremgangsmaate ved fremstilling av 2-pyridylmethyl-thio- og -sulfinylbenzimidazoler

Info

Publication number
NO844836L
NO844836L NO844836A NO844836A NO844836L NO 844836 L NO844836 L NO 844836L NO 844836 A NO844836 A NO 844836A NO 844836 A NO844836 A NO 844836A NO 844836 L NO844836 L NO 844836L
Authority
NO
Norway
Prior art keywords
pyridylmethyl
thio
procedure
preparation
sulfinyl benzimidazoles
Prior art date
Application number
NO844836A
Other languages
English (en)
Other versions
NO164473C (no
NO164473B (no
Inventor
John Charles Sih
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of NO844836L publication Critical patent/NO844836L/no
Publication of NO164473B publication Critical patent/NO164473B/no
Publication of NO164473C publication Critical patent/NO164473C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO844836A 1983-12-05 1984-12-04 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2-pyridylmethyl-thio- og -sulfinylbenzimidazoler. NO164473C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55808783A 1983-12-05 1983-12-05
US06/648,118 US4575554A (en) 1983-12-05 1984-09-06 Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Publications (3)

Publication Number Publication Date
NO844836L true NO844836L (no) 1985-06-06
NO164473B NO164473B (no) 1990-07-02
NO164473C NO164473C (no) 1990-10-10

Family

ID=27071629

Family Applications (1)

Application Number Title Priority Date Filing Date
NO844836A NO164473C (no) 1983-12-05 1984-12-04 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 2-pyridylmethyl-thio- og -sulfinylbenzimidazoler.

Country Status (16)

Country Link
US (1) US4575554A (no)
EP (1) EP0150586B1 (no)
JP (1) JPS60139689A (no)
KR (1) KR890000382B1 (no)
AU (1) AU571907B2 (no)
DE (1) DE3484565D1 (no)
DK (1) DK577584A (no)
ES (1) ES8603711A1 (no)
FI (1) FI83418C (no)
GR (1) GR81143B (no)
IE (1) IE58431B1 (no)
IL (1) IL73433A (no)
MX (1) MX160796A (no)
NO (1) NO164473C (no)
NZ (1) NZ210135A (no)
PH (1) PH19962A (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
EP0178438A1 (en) * 1984-09-19 1986-04-23 Beecham Group Plc Novel compounds
KR890000387B1 (ko) * 1984-09-24 1989-03-16 디 엎존 캄파니 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
US4743609A (en) * 1985-02-12 1988-05-10 Banyu Pharmaceutical Co., Ltd. Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
EP0234485B1 (de) * 1986-02-20 1992-04-01 Hoechst Aktiengesellschaft Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
EP0425505B1 (en) * 1988-06-30 1993-03-17 The Upjohn Company Transdermal antisecretory agents for gastrointestinal disease
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
WO1994013290A1 (de) * 1992-12-10 1994-06-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien
ATE198887T1 (de) * 1993-06-29 2001-02-15 Byk Gulden Lomberg Chem Fab Substituierte arylthioalkylthiopyridine
AU698249B2 (en) * 1994-06-10 1998-10-29 Altana Pharma Ag Thiopyridines for combating (helicobacter) bacteria
ES2236628T3 (es) * 1995-09-21 2005-07-16 Pharma Pass Ii Llc Composicion farmaceutica que contiene un omeprazol labil de acido, y procedimiento para su preparacion.
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
WO2002026210A2 (en) * 2000-09-29 2002-04-04 Geneva Pharmaceuticals Inc. Proton pump inhibitor formulation
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
CN112142653B (zh) * 2020-10-22 2022-02-11 成都百泉生物医药科技有限公司 奥美拉唑中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
IL66340A (en) * 1981-08-13 1986-08-31 Haessle Ab Pharmaceutical compositions comprising pyridylmethyl-thiobenzimidazole derivatives,certain such novel derivatives and their preparation
JPS58135881A (ja) * 1981-11-05 1983-08-12 ビク−グルデン・ロムベルク・ヘミツシエ・フアブリク・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング 置換ベンズイミダゾ−ル類、その製造方法と利用、およびこれを含む医薬
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds

Also Published As

Publication number Publication date
IE58431B1 (en) 1993-09-22
ES538249A0 (es) 1986-01-16
FI83418C (fi) 1991-07-10
NZ210135A (en) 1989-01-06
IE843095L (en) 1985-06-05
KR850004483A (ko) 1985-07-15
EP0150586A3 (en) 1985-08-28
DK577584D0 (da) 1984-12-04
MX160796A (es) 1990-05-22
IL73433A0 (en) 1985-02-28
EP0150586B1 (en) 1991-05-08
IL73433A (en) 1988-11-30
JPS60139689A (ja) 1985-07-24
DK577584A (da) 1985-06-06
ES8603711A1 (es) 1986-01-16
FI844755L (fi) 1985-06-06
FI844755A0 (fi) 1984-12-03
EP0150586A2 (en) 1985-08-07
GR81143B (en) 1985-04-04
AU3564384A (en) 1985-06-13
US4575554A (en) 1986-03-11
NO164473C (no) 1990-10-10
NO164473B (no) 1990-07-02
FI83418B (fi) 1991-03-28
PH19962A (en) 1986-08-20
JPH0572392B2 (no) 1993-10-12
DE3484565D1 (de) 1991-06-13
KR890000382B1 (ko) 1989-03-15
AU571907B2 (en) 1988-04-28

Similar Documents

Publication Publication Date Title
NO844836L (no) Fremgangsmaate ved fremstilling av 2-pyridylmethyl-thio- og -sulfinylbenzimidazoler
NO843956L (no) Fremgangsmaate for fremstilling av karboksyalkenamido-cefalosporiner
RO90861A (ro) Procedeu pentru prepararea etielnglicolului
NO841158L (no) Fremgangsmaate for fremstilling av 2-azetidin-4-substituerte forbindelser
NO171556C (no) Fremgangsmaate for fremstilling av azitromycin dihydrat
NO811731L (no) Fremgangsmaate for fremstilling av imidazo-rifamycin-derivater
NO813678L (no) Fremgangsmaate for fremstilling av karbostyrilderivater
NO173498C (no) Analogifremgangsmaate for fremstilling av substituerte 9-amino-tetrahydroakridiner
NO844388L (no) Fremgangsmaate for fremstilling av aminoeteralkoholer
NO814065L (no) Fremgansmaate for fremstilling av imidazolylfenylamidiner
NO844631L (no) Fremgangsmaate for fremstilling av tremasse
ES537502A0 (es) Procedimiento para la preparacion de imidazolinonas
NO845207L (no) Fremgangsmaate for fremstilling av diaminopolyalkenyletere
NO830988L (no) Fremgangsmaate ved fremstilling av stabiliserte pge-derivater
NO170019C (no) Fremgangsmaate for fremstilling av deglucoteicoplanin (antibiotikum l 17392)
NO843055L (no) Fremgangsmaate ved fremstilling av cephalosporinderivater
NO842868L (no) Framgangsmaate for framstilling av alkoholer
NO844118L (no) Fremgangsmaate for fremstilling av imidazolinderivater
NO832830L (no) Fremgangsmaate for fremstilling av alfa-arylalkansyrer
NO833531L (no) Fremgangsmaate for fremstilling av 7-substituerte-3-vinyl-3-cefem-forbindelser
NO845193L (no) Fremgangsmaate ved fremstilling av gonadoliberinderivater
NO830176L (no) Fremgangsmaate for fremstilling av ultrarent toriumfluorid
NO830784L (no) Fremgangsmaate for fremstilling av tioetere
NO813477L (no) Fremgangsmaate for fremstilling av karbostyrilderivater
NO830309L (no) Fremgangsmaate for fremstilling av tennsats for varmeanordning