GR81143B - Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents - Google Patents

Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents

Info

Publication number
GR81143B
GR81143B GR81143A GR840181143A GR81143B GR 81143 B GR81143 B GR 81143B GR 81143 A GR81143 A GR 81143A GR 840181143 A GR840181143 A GR 840181143A GR 81143 B GR81143 B GR 81143B
Authority
GR
Greece
Prior art keywords
pyridylmethyl
thio
substituted
antisecretory agents
gastric antisecretory
Prior art date
Application number
GR81143A
Other languages
English (en)
Inventor
Sih Charles John
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GR81143B publication Critical patent/GR81143B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR81143A 1983-12-05 1984-12-03 Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents GR81143B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US55808783A 1983-12-05 1983-12-05
US06/648,118 US4575554A (en) 1983-12-05 1984-09-06 Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Publications (1)

Publication Number Publication Date
GR81143B true GR81143B (en) 1985-04-04

Family

ID=27071629

Family Applications (1)

Application Number Title Priority Date Filing Date
GR81143A GR81143B (en) 1983-12-05 1984-12-03 Substituted 2-pyridylmethyl-thio and sulfinyl benzimidazoles as gastric antisecretory agents

Country Status (16)

Country Link
US (1) US4575554A (el)
EP (1) EP0150586B1 (el)
JP (1) JPS60139689A (el)
KR (1) KR890000382B1 (el)
AU (1) AU571907B2 (el)
DE (1) DE3484565D1 (el)
DK (1) DK577584A (el)
ES (1) ES8603711A1 (el)
FI (1) FI83418C (el)
GR (1) GR81143B (el)
IE (1) IE58431B1 (el)
IL (1) IL73433A (el)
MX (1) MX160796A (el)
NO (1) NO164473C (el)
NZ (1) NZ210135A (el)
PH (1) PH19962A (el)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161160B (en) * 1984-07-06 1989-05-24 Fisons Plc Heterocyclic sulphinyl compounds
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
EP0178438A1 (en) * 1984-09-19 1986-04-23 Beecham Group Plc Novel compounds
KR890000387B1 (ko) * 1984-09-24 1989-03-16 디 엎존 캄파니 2-(피리딜알켄술 피닐)벤즈 이미드아졸류의 n-치환 유도체의 제조방법
JO1406B1 (en) * 1984-11-02 1986-11-30 سميث كلاين اند فرينش لابوراتوريز ليمتد Chemical compounds
US4743609A (en) * 1985-02-12 1988-05-10 Banyu Pharmaceutical Co., Ltd. Indole derivatives having gastric and antisecretory and cytoprotective properties, and pharmaceutical preparations containing same
EP0234485B1 (de) * 1986-02-20 1992-04-01 Hoechst Aktiengesellschaft Substituierte Thienoimidazol-Derivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung als Magensäuresekretionshemmer
WO1987005296A1 (en) * 1986-03-07 1987-09-11 Pfizer Inc. 2-[(2-pyridyl)methylsulfinyl]thienoimidazoles and related compounds as antiulcer agents
US4772619A (en) * 1986-07-17 1988-09-20 G. D. Searle & Co. [(1H-benzimidazol-2-ylsulfinyl)methyl]-2-pyridinamines
EP0425505B1 (en) * 1988-06-30 1993-03-17 The Upjohn Company Transdermal antisecretory agents for gastrointestinal disease
US4965269A (en) * 1989-12-20 1990-10-23 Ab Hassle Therapeutically active chloro substituted benzimidazoles
EP0673246A1 (de) * 1992-12-10 1995-09-27 Byk Gulden Lomberg Chemische Fabrik GmbH Verwendung von alkylthiopyridinen zur bekämpfung von heliobacter-bakterien
CA2166327A1 (en) * 1993-06-29 1995-01-12 Bernhard Kohl Substituted arylthioalkylthiopyridines
RU2142459C1 (ru) * 1994-06-10 1999-12-10 Бык Гульден Ломберг Хемише Фабрик Гмбх Тиопиридины для борьбы с бактериями helicobakter
SK284291B6 (sk) * 1995-09-21 2005-01-03 Pharma Pass L.L.C. Farmaceutická kompozícia vo forme tabliet alebo mikrotabliet obsahujúca acidolabilný omeprazol a spôsob jej prípravy
US6245913B1 (en) 1999-06-30 2001-06-12 Wockhardt Europe Limited Synthetic procedure for 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methylthio]-IH-benzimidazole hydrochloride and its conversion to omeprazole
WO2002026210A2 (en) * 2000-09-29 2002-04-04 Geneva Pharmaceuticals Inc. Proton pump inhibitor formulation
US20030228363A1 (en) * 2002-06-07 2003-12-11 Patel Mahendra R. Stabilized pharmaceutical compositons containing benzimidazole compounds
US20060024362A1 (en) 2004-07-29 2006-02-02 Pawan Seth Composition comprising a benzimidazole and process for its manufacture
CN112142653B (zh) * 2020-10-22 2022-02-11 成都百泉生物医药科技有限公司 奥美拉唑中间体的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
ZA825106B (en) * 1981-08-13 1983-04-27 Haessle Ab Novel pharmaceutical compositions
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
JPS58135881A (ja) * 1981-11-05 1983-08-12 ビク−グルデン・ロムベルク・ヘミツシエ・フアブリク・ゲゼルシヤフト・ミト・ベシユレンクテル・ハフツング 置換ベンズイミダゾ−ル類、その製造方法と利用、およびこれを含む医薬
DE3216843C2 (de) * 1982-05-05 1986-10-23 Ludwig Heumann & Co GmbH, 8500 Nürnberg 3-Thiomethyl-pyridin-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
SE8300736D0 (sv) * 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds

Also Published As

Publication number Publication date
NO164473C (no) 1990-10-10
NO844836L (no) 1985-06-06
JPH0572392B2 (el) 1993-10-12
EP0150586A3 (en) 1985-08-28
ES8603711A1 (es) 1986-01-16
PH19962A (en) 1986-08-20
IL73433A0 (en) 1985-02-28
IL73433A (en) 1988-11-30
JPS60139689A (ja) 1985-07-24
KR890000382B1 (ko) 1989-03-15
FI83418B (fi) 1991-03-28
AU571907B2 (en) 1988-04-28
DE3484565D1 (de) 1991-06-13
FI83418C (fi) 1991-07-10
MX160796A (es) 1990-05-22
EP0150586A2 (en) 1985-08-07
NZ210135A (en) 1989-01-06
KR850004483A (ko) 1985-07-15
AU3564384A (en) 1985-06-13
DK577584D0 (da) 1984-12-04
ES538249A0 (es) 1986-01-16
IE58431B1 (en) 1993-09-22
NO164473B (no) 1990-07-02
DK577584A (da) 1985-06-06
FI844755L (fi) 1985-06-06
FI844755A0 (fi) 1984-12-03
IE843095L (en) 1985-06-05
EP0150586B1 (en) 1991-05-08
US4575554A (en) 1986-03-11

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