NO832430L - Fremgangsmaate for fremstilling av terapeutisk aktive fenyleddiksyre-derivater - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive fenyleddiksyre-derivater

Info

Publication number
NO832430L
NO832430L NO832430A NO832430A NO832430L NO 832430 L NO832430 L NO 832430L NO 832430 A NO832430 A NO 832430A NO 832430 A NO832430 A NO 832430A NO 832430 L NO832430 L NO 832430L
Authority
NO
Norway
Prior art keywords
phenyledic
procedure
preparation
acid derivatives
therapeutic active
Prior art date
Application number
NO832430A
Other languages
English (en)
Other versions
NO159590B (no
NO159590C (no
Inventor
Wolfgang Grell
Rudolf Hurnaus
Gerhart Griss
Robert Sauter
Eckhard Rupprecht
Joachim Kaehling
Bernhard Eisele
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19823225188 external-priority patent/DE3225188A1/de
Priority claimed from DE19823225155 external-priority patent/DE3225155A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO832430L publication Critical patent/NO832430L/no
Publication of NO159590B publication Critical patent/NO159590B/no
Publication of NO159590C publication Critical patent/NO159590C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40Acylated substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/12Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
    • C07D295/135Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Fertilizers (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO832430A 1982-07-06 1983-07-04 Analogifremgangsm te for fremstilling av terapeutisk aktive fenyleddiksyre-derivater. NO159590C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19823225188 DE3225188A1 (de) 1982-07-06 1982-07-06 Neue phenylessigsaeurederivate, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE19823225155 DE3225155A1 (de) 1982-07-06 1982-07-06 Neue n-benzylamide und deren salze, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO832430L true NO832430L (no) 1984-01-09
NO159590B NO159590B (no) 1988-10-10
NO159590C NO159590C (no) 1989-01-18

Family

ID=25802849

Family Applications (1)

Application Number Title Priority Date Filing Date
NO832430A NO159590C (no) 1982-07-06 1983-07-04 Analogifremgangsm te for fremstilling av terapeutisk aktive fenyleddiksyre-derivater.

Country Status (21)

Country Link
EP (1) EP0099017B1 (no)
KR (1) KR900004925B1 (no)
AU (1) AU561274B2 (no)
CA (1) CA1214773A (no)
CS (1) CS240970B2 (no)
DD (1) DD210907A5 (no)
DE (1) DE3375783D1 (no)
DK (1) DK159850C (no)
ES (4) ES523869A0 (no)
FI (1) FI78477C (no)
GB (1) GB2124220B (no)
GR (1) GR78661B (no)
HU (1) HU195651B (no)
IE (1) IE56171B1 (no)
IL (1) IL69172A (no)
NO (1) NO159590C (no)
NZ (1) NZ204814A (no)
PL (1) PL143992B1 (no)
PT (1) PT76986B (no)
SU (1) SU1170969A3 (no)
YU (1) YU146883A (no)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312924A (en) 1983-12-30 1994-05-17 Dr. Karl Thomae Gmbh Phenylacetic acid benzylamides
DE3347565A1 (de) * 1983-12-30 1985-07-11 Thomae Gmbh Dr K Neue phenylessigsaeurederivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
FR2763590B1 (fr) * 1997-05-22 2000-03-24 Synthelabo Derives d'acides[[[(arylmethyl)amino]carbonyl] alkyl]- aromatiques, leur preparation et leur application en therapeutique
JP4550811B2 (ja) 2003-06-09 2010-09-22 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング パピローマウイルスのインヒビター
EP2364977A1 (en) 2010-01-26 2011-09-14 Reuter Chemische Apparatebau KG Process for the enantiomeric enrichment of 3-methyl-1-(2-piperidinophenyl)-1-butylamine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE764238A (fr) * 1971-03-17 1971-09-13 Lilly Industries Ltd Derives de phenylalkylamine
NL7305171A (no) * 1973-04-13 1974-10-15
DE3100575A1 (de) * 1981-01-10 1982-09-02 Dr. Karl Thomae Gmbh, 7950 Biberach "neue benzoesaeuren, ihre herstellung und ihre verwendung als arzneimittel"

Also Published As

Publication number Publication date
NZ204814A (en) 1986-10-08
ES529807A0 (es) 1984-11-01
PT76986B (de) 1986-04-11
GR78661B (no) 1984-09-27
GB8318250D0 (en) 1983-08-10
DK159850C (da) 1991-05-06
SU1170969A3 (ru) 1985-07-30
ES529806A0 (es) 1984-11-01
FI78477B (fi) 1989-04-28
HU195651B (en) 1988-06-28
DE3375783D1 (en) 1988-04-07
FI832374L (fi) 1984-01-07
FI78477C (fi) 1989-08-10
DK310883D0 (da) 1983-07-05
ES8501382A1 (es) 1984-11-16
ES8500742A1 (es) 1984-11-01
GB2124220A (en) 1984-02-15
ES523869A0 (es) 1984-11-16
KR900004925B1 (ko) 1990-07-12
CS240970B2 (en) 1986-03-13
IL69172A0 (en) 1983-11-30
ES8500924A1 (es) 1984-11-01
YU146883A (en) 1986-04-30
CA1214773A (en) 1986-12-02
KR840005438A (ko) 1984-11-12
AU561274B2 (en) 1987-05-07
EP0099017A2 (de) 1984-01-25
NO159590B (no) 1988-10-10
IL69172A (en) 1987-10-20
ES8500923A1 (es) 1984-11-01
ES529808A0 (es) 1984-11-01
AU1657683A (en) 1984-01-12
EP0099017B1 (de) 1988-03-02
IE831573L (en) 1984-01-06
PT76986A (de) 1983-08-01
PL242873A1 (en) 1984-09-10
PL143992B1 (en) 1988-04-30
DK310883A (da) 1984-01-07
NO159590C (no) 1989-01-18
DD210907A5 (de) 1984-06-27
GB2124220B (en) 1985-11-13
IE56171B1 (en) 1991-05-08
DK159850B (da) 1990-12-17
FI832374A0 (fi) 1983-06-29
EP0099017A3 (en) 1984-02-22

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