NO811632L - Sulfaterte polysakkarider, deres fremstilling og bruk - Google Patents

Sulfaterte polysakkarider, deres fremstilling og bruk

Info

Publication number
NO811632L
NO811632L NO811632A NO811632A NO811632L NO 811632 L NO811632 L NO 811632L NO 811632 A NO811632 A NO 811632A NO 811632 A NO811632 A NO 811632A NO 811632 L NO811632 L NO 811632L
Authority
NO
Norway
Prior art keywords
polysaccarides
sulphated
preparation
sulphated polysaccarides
Prior art date
Application number
NO811632A
Other languages
English (en)
Other versions
NO156129B (no
NO156129C (no
Inventor
Jean Mardiguian
Original Assignee
Pharmindustrie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9241965&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO811632(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmindustrie filed Critical Pharmindustrie
Publication of NO811632L publication Critical patent/NO811632L/no
Publication of NO156129B publication Critical patent/NO156129B/no
Publication of NO156129C publication Critical patent/NO156129C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polymers & Plastics (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
NO811632A 1980-05-14 1981-05-13 Fremgangsmaate for fremstilling av blandinger av sulfaterte polysakkarider med en generell heparinpolysakkarid-struktur. NO156129C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8010791A FR2482611B1 (fr) 1980-05-14 1980-05-14 Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments

Publications (3)

Publication Number Publication Date
NO811632L true NO811632L (no) 1981-11-16
NO156129B NO156129B (no) 1987-04-21
NO156129C NO156129C (no) 1987-07-29

Family

ID=9241965

Family Applications (1)

Application Number Title Priority Date Filing Date
NO811632A NO156129C (no) 1980-05-14 1981-05-13 Fremgangsmaate for fremstilling av blandinger av sulfaterte polysakkarider med en generell heparinpolysakkarid-struktur.

Country Status (23)

Country Link
EP (1) EP0040144B1 (no)
JP (1) JPS6051482B2 (no)
KR (1) KR840001753B1 (no)
AR (1) AR229510A1 (no)
AT (1) AT384428B (no)
AU (1) AU535791B2 (no)
CA (1) CA1181744A (no)
DE (1) DE3165361D1 (no)
DK (1) DK168824B1 (no)
DZ (1) DZ294A1 (no)
ES (1) ES502199A0 (no)
FI (1) FI67865C (no)
FR (1) FR2482611B1 (no)
GR (1) GR82283B (no)
HU (1) HU188667B (no)
IE (1) IE51283B1 (no)
IL (1) IL62866A (no)
IN (1) IN152828B (no)
MA (1) MA19143A1 (no)
NO (1) NO156129C (no)
NZ (1) NZ197081A (no)
PT (1) PT73024B (no)
ZA (1) ZA813176B (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2548672A1 (fr) * 1983-07-04 1985-01-11 Pharmuka Lab Oligosaccharides sulfates et leur utilisation comme medicaments
DE3422407A1 (de) * 1984-06-16 1986-03-06 B. Braun Melsungen Ag, 3508 Melsungen Verwendung von heparinderivaten zur selektiven extrakorporalen praezipitation von low-density-lipoproteinen aus vollserum oder plasma
EP0209924A1 (en) * 1985-07-12 1987-01-28 Akzo N.V. New anti-trombosis agent based on glycosaminoglycan, process for its preparation, and pharmaceutical compositions
FR2584728B1 (fr) * 1985-07-12 1987-11-20 Choay Sa Procede de sulfatation de glycosaminoglycanes et de leurs fragments
ES2003197A6 (es) * 1987-01-05 1988-10-16 Rovi Lab Farmaceut Sa Procedimiento de despolimerizacion de la heparina para la obtencion de una heparina de bajo peso molecular dotada de actividad antitrombotica
EP0337327A1 (en) * 1988-04-09 1989-10-18 Bioiberica, S.A. Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin
IT1230582B (it) 1988-10-21 1991-10-28 Opocrin S P A Lab Farmabiologi Oliogosaccaridi di dermatan solfato ed eparina aventi attivita' antiaterosclerotica
IT1234826B (it) * 1989-01-30 1992-05-29 Alfa Wassermann Spa Derivati eparinici e procedimento per la loro preparazione
US5340932A (en) * 1989-08-18 1994-08-23 Ajorca S.A. Substances with heparin-like structure and their method of production
USRE38743E1 (en) 1990-06-26 2005-06-14 Aventis Pharma S.A. Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events
FR2663639B1 (fr) * 1990-06-26 1994-03-18 Rhone Poulenc Sante Melanges de polysaccharides de bas poids moleculaires procede de preparation et utilisation.
DE4121115B9 (de) * 1990-06-26 2005-09-29 Aventis Pharma S.A. Gemische sulfatierter Polysaccharide mit der Grundstruktur der das Heparin bildenden Polysaccharide und mit niedrigem Molekulargewicht, deren Herstellungsverfahren und Verwendung
US5707973A (en) * 1991-04-23 1998-01-13 Rhone-Poulenc Rorer S.A. Sulfated polysaccharids for treatment or prevention of thromboses
IT1256236B (it) * 1992-12-23 1995-11-29 Mediolanum Farmaceutici Srl Oligosaccaridi aventi attivita' biologica e procedimento per la loro preparazione di glicosaminoglicani
ES2077533B1 (es) * 1994-02-28 1996-07-01 Bioiberica Procedimiento de obtencion de fracciones de oligosacaridos por despolimerizacion quimica de heparina.
DK0946185T4 (da) * 1996-11-27 2010-08-30 Aventis Pharma Inc Farmaceutisk præparat, som omfatter en forbindelse med anti-Xa-aktivitet og en blodpladeaggregations antagonistforbindelse
AUPO556297A0 (en) 1997-03-11 1997-04-10 Australian National University, The Sulfated oligosaccharides having anticoagulant/ antithrombotic activity
JP4897991B2 (ja) * 1999-07-23 2012-03-14 ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ 超低分子量ヘパリン組成物
FR2811992B1 (fr) * 2000-07-21 2003-07-04 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
US6969705B2 (en) 2000-07-21 2005-11-29 Aventis Pharma S.A. Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
ES2282368T3 (es) * 2002-06-20 2007-10-16 Chemi S.P.A. Procedimiento para la preparacion de esteres de heparina.
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
FR2845686B1 (fr) * 2002-10-10 2013-08-30 Aventis Pharma Sa Melanges de polysaccharides derives d'heparine, leur preparation et les compositions pharmaceutiques les contenant
JP2006096668A (ja) * 2002-11-08 2006-04-13 Ono Pharmaceut Co Ltd エラスターゼ阻害剤と血液凝固系および／または線溶系酵素阻害剤との組み合わせからなる医薬
DE10260958A1 (de) * 2002-12-20 2004-07-08 Sustech Gmbh & Co. Kg Kompositmaterialien aus Calciumverbindungen und Glucuronsäure- und/oder Iduronsäurehaltigen Polysacchariden
US7956046B2 (en) 2003-07-24 2011-06-07 Aventis Pharma S.A. Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them
ITMI20031679A1 (it) * 2003-08-29 2005-02-28 Opocrin Spa Processo per la produzione di eparine a basso peso
EP1582531A1 (en) 2004-03-24 2005-10-05 Aventis Pharma S.A. Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products
US20050261241A1 (en) 2004-05-19 2005-11-24 Celsus Biopharmaceuticals, Inc. Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses
ATE552004T1 (de) 2005-11-30 2012-04-15 Istituto G Ronzoni Oral verabreichbare heparinderivate
ES2340902B1 (es) * 2008-07-01 2011-05-03 Laboratorios Farmaceuticos Rovi, S.A. Composicion farmaceutica con glicosaminoglicanos y su uso en tratamiento de ulceras cronicas.
WO2012036152A1 (ja) * 2010-09-14 2012-03-22 国立大学法人 宮崎大学 高純度ヘパリンおよびその製造方法
CA3085285A1 (en) 2017-12-11 2019-06-20 Biological E Limited Process for the preparation of low molecular weight heparin
WO2022015794A1 (en) 2020-07-14 2022-01-20 Optimvia, Llc Methods for synthesizing non-anticoagulant heparan sulfate
EP3997238A1 (en) 2019-07-09 2022-05-18 Optimvia, LLC Methods for synthesizing anticoagulant polysaccharides
ES2792298B2 (es) 2020-04-27 2022-04-20 Farm Rovi Lab Sa Procedimiento para la obtencion de heparinas de bajo peso molecular y heparinas de bajo peso molecular obtenidas por el mismo

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3835112A (en) * 1970-06-08 1974-09-10 Etude Et D Exploit De Marques Heparin esters
CA1136620A (en) * 1979-01-08 1982-11-30 Ulf P.F. Lindahl Heparin fragments having selective anticoagulation activity

Also Published As

Publication number Publication date
ATA213681A (de) 1987-04-15
DE3165361D1 (en) 1984-09-13
FI67865C (fi) 1985-06-10
JPS5710601A (en) 1982-01-20
ZA813176B (en) 1982-05-26
AR229510A1 (es) 1983-09-15
MA19143A1 (fr) 1981-12-31
DK168824B1 (da) 1994-06-20
AU7051981A (en) 1981-11-19
KR830006333A (ko) 1983-09-24
HU188667B (en) 1986-05-28
IN152828B (no) 1984-04-14
FI67865B (fi) 1985-02-28
NO156129B (no) 1987-04-21
EP0040144A1 (fr) 1981-11-18
DK211981A (da) 1981-11-15
IE811074L (en) 1981-11-14
JPS6051482B2 (ja) 1985-11-14
IL62866A0 (en) 1981-07-31
FR2482611B1 (fr) 1986-03-07
CA1181744A (fr) 1985-01-29
AT384428B (de) 1987-11-10
KR840001753B1 (ko) 1984-10-19
NZ197081A (en) 1984-07-31
ES8206555A1 (es) 1982-08-16
FI811469L (fi) 1981-11-15
IL62866A (en) 1984-06-29
PT73024A (fr) 1981-06-01
DZ294A1 (fr) 2004-09-13
ES502199A0 (es) 1982-08-16
IE51283B1 (en) 1986-11-26
FR2482611A1 (fr) 1981-11-20
NO156129C (no) 1987-07-29
HUT34769A (en) 1985-04-28
PT73024B (fr) 1982-07-01
AU535791B2 (en) 1984-04-05
GR82283B (no) 1984-12-13
EP0040144B1 (fr) 1984-08-08

Similar Documents

Publication Publication Date Title
NO811632L (no) Sulfaterte polysakkarider, deres fremstilling og bruk
DK155583A (da) Hydantoiner, deres fremstilling og anvendelse
DK437883A (da) Vandige mikroemulsioner, deres fremstilling og anvendelse
DK168579A (da) Corticoid-21-halogen-17-alkylcarbonater deres fremstilling og anvendelse
DK313077A (da) Polygalactosido-sucrose-poly (h)-sulfater deres fremstilling og anvendelser
DK301980A (da) Nikkomyciner i,j, og n, deres fremstilling og anvendelse
DK441184A (da) Pyrethroid-holdige formlegemer, deres fremstilling og anvendelse
DK227884D0 (da) 1-pyrimidinyloxy-3-hetarylalkyl-amino-2-propanoler,deres fremstilling og anvendelse
DK594884A (da) Tvaerbundne polymerisater, deres fremstilling og anvendelse
DK168879A (da) Beta-lactamantibiotika og deres fremstilling
DK291478A (da) N!-phenyl-n-methylurinstofderivater deres fremstilling og anvendelse
DK616584A (da) Pyrrolderivater, deres fremstilling og anvendelse
DK172183D0 (da) Ozazolderivater, deres fremstilling og anvendelse
NO821159L (no) 2-piperazinopyrimidin og deres fremstilling.
DK58581A (da) Thiolestere deres fremstilling og anvendelse
DK286480A (da) Oxinethere deres fremstilling og anvendelse
DK514382A (da) Azolylvinyldithioacetaler, deres fremstilling og anvendelse
NO803713L (no) Bensement og anvendelse derav.
DK319478A (da) Angiotensinpeptider og deres fremstilling
DK254077A (da) Benzylcyanocetaler deres fremstilling og anvendelse
DK157935C (da) Acetoacetylaminophenyl-disazo-diphenylpigmenter, deres fremstilling og anvendelse
DK36479A (da) 2,6-dinitrobenzenaminer deres fremstilling og anvendelse
DK156783D0 (da) N-pteridinylurinstoffer, deres fremstilling og anvendelse
DK356481A (da) Hetero-prostaglandinderivater og deres fremstilling
DK516982A (da) P-phenylendiaminer, deres fremstilling og anvendelse

Legal Events

Date Code Title Description
MK1K Patent expired

Free format text: EXPIRED IN MAY 2001