IL62866A0 - Mixtures of sulphated polysaccharides,their preparation and pharmaceutical compositions containing them - Google Patents
Mixtures of sulphated polysaccharides,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL62866A0 IL62866A0 IL62866A IL6286681A IL62866A0 IL 62866 A0 IL62866 A0 IL 62866A0 IL 62866 A IL62866 A IL 62866A IL 6286681 A IL6286681 A IL 6286681A IL 62866 A0 IL62866 A0 IL 62866A0
- Authority
- IL
- Israel
- Prior art keywords
- mixtures
- preparation
- pharmaceutical compositions
- compositions containing
- sulphated polysaccharides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Materials Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Polymers & Plastics (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8010791A FR2482611B1 (en) | 1980-05-14 | 1980-05-14 | NOVEL SULFATED POLYSACCHARIDES, METHODS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS |
Publications (2)
Publication Number | Publication Date |
---|---|
IL62866A0 true IL62866A0 (en) | 1981-07-31 |
IL62866A IL62866A (en) | 1984-06-29 |
Family
ID=9241965
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL62866A IL62866A (en) | 1980-05-14 | 1981-05-13 | Mixtures of sulphated polysaccharides,their preparation and pharmaceutical compositions containing them |
Country Status (23)
Country | Link |
---|---|
EP (1) | EP0040144B1 (en) |
JP (1) | JPS6051482B2 (en) |
KR (1) | KR840001753B1 (en) |
AR (1) | AR229510A1 (en) |
AT (1) | AT384428B (en) |
AU (1) | AU535791B2 (en) |
CA (1) | CA1181744A (en) |
DE (1) | DE3165361D1 (en) |
DK (1) | DK168824B1 (en) |
DZ (1) | DZ294A1 (en) |
ES (1) | ES502199A0 (en) |
FI (1) | FI67865C (en) |
FR (1) | FR2482611B1 (en) |
GR (1) | GR82283B (en) |
HU (1) | HU188667B (en) |
IE (1) | IE51283B1 (en) |
IL (1) | IL62866A (en) |
IN (1) | IN152828B (en) |
MA (1) | MA19143A1 (en) |
NO (1) | NO156129C (en) |
NZ (1) | NZ197081A (en) |
PT (1) | PT73024B (en) |
ZA (1) | ZA813176B (en) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2548672A1 (en) * | 1983-07-04 | 1985-01-11 | Pharmuka Lab | SULPHATE OLIGOSACCHARIDES AND THEIR USE AS MEDICAMENTS |
DE3422407A1 (en) * | 1984-06-16 | 1986-03-06 | B. Braun Melsungen Ag, 3508 Melsungen | USE OF HEPARINE DERIVATIVES FOR SELECTIVE EXTRA-CORPORAL PRECIPITATION OF LOW-DENSITY-LIPOPROTEINS FROM FULL SERUM OR PLASMA |
FR2584728B1 (en) * | 1985-07-12 | 1987-11-20 | Choay Sa | PROCESS FOR THE SULFATION OF GLYCOSAMINOGLYCANS AND THEIR FRAGMENTS |
EP0209924A1 (en) * | 1985-07-12 | 1987-01-28 | Akzo N.V. | New anti-trombosis agent based on glycosaminoglycan, process for its preparation, and pharmaceutical compositions |
ES2003197A6 (en) * | 1987-01-05 | 1988-10-16 | Rovi Lab Farmaceut Sa | Process for the depolymerization of heparin for obtaining heparin with a low molecular weight and having an antithrombotic activity. |
EP0337327A1 (en) * | 1988-04-09 | 1989-10-18 | Bioiberica, S.A. | Process for the preparation of new oligosaccharide fractions by controlled chemical depolimerization of heparin |
IT1230582B (en) | 1988-10-21 | 1991-10-28 | Opocrin S P A Lab Farmabiologi | DERMATAN SULPHATE AND HEPARIN OILGOSACCHARID WITH ANTI-THEROSCLEROTIC ACTIVITIES |
IT1234826B (en) * | 1989-01-30 | 1992-05-29 | Alfa Wassermann Spa | HEPARIN DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION |
US5340932A (en) * | 1989-08-18 | 1994-08-23 | Ajorca S.A. | Substances with heparin-like structure and their method of production |
DE4121115B9 (en) * | 1990-06-26 | 2005-09-29 | Aventis Pharma S.A. | Mixtures of sulfated polysaccharides with the basic structure of heparin-forming polysaccharides and low molecular weight, their method of preparation and use |
FR2663639B1 (en) * | 1990-06-26 | 1994-03-18 | Rhone Poulenc Sante | LOW MOLECULAR WEIGHT POLYSACCHARIDE BLENDS PROCESS FOR PREPARATION AND USE. |
USRE38743E1 (en) | 1990-06-26 | 2005-06-14 | Aventis Pharma S.A. | Mixtures of particular LMW heparinic polysaccharides for the prophylaxis/treatment of acute thrombotic events |
US5707973A (en) * | 1991-04-23 | 1998-01-13 | Rhone-Poulenc Rorer S.A. | Sulfated polysaccharids for treatment or prevention of thromboses |
IT1256236B (en) * | 1992-12-23 | 1995-11-29 | Mediolanum Farmaceutici Srl | OLIGOSACCHARIDES WITH BIOLOGICAL ACTIVITY AND PROCEDURE FOR THEIR PREPARATION OF GLYCOSAMINOGLICANS |
ES2077533B1 (en) * | 1994-02-28 | 1996-07-01 | Bioiberica | PROCEDURE FOR OBTAINING OLIGOSACCHARIDE FRACTIONS BY CHEMICAL DEPOLYMERIZATION OF HEPARIN. |
PT946185E (en) * | 1996-11-27 | 2005-02-28 | Aventis Pharm Prod Inc | PHARMACEUTICAL COMPOSITION COMPOSING A COMPOUND WHICH HAS ANTI-XA ACTIVITY AND AN ANTAGONIST COMPOUND OF THE PLAQUETARY AGGREGATION |
AUPO556297A0 (en) * | 1997-03-11 | 1997-04-10 | Australian National University, The | Sulfated oligosaccharides having anticoagulant/ antithrombotic activity |
JP4897991B2 (en) * | 1999-07-23 | 2012-03-14 | ラボラトリオス ファルマセウティコス ロビ ソシエダッド アノニマ | Ultra low molecular weight heparin composition |
US6969705B2 (en) * | 2000-07-21 | 2005-11-29 | Aventis Pharma S.A. | Compositions of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
FR2811992B1 (en) * | 2000-07-21 | 2003-07-04 | Aventis Pharma Sa | MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
ES2282368T3 (en) * | 2002-06-20 | 2007-10-16 | Chemi S.P.A. | PROCEDURE FOR THE PREPARATION OF ESTERES DE HEPARINA. |
US20040171819A1 (en) | 2002-10-10 | 2004-09-02 | Aventis Pharma S.A. | Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them |
FR2845686B1 (en) * | 2002-10-10 | 2013-08-30 | Aventis Pharma Sa | MIXTURES OF HEPARIN-DERIVED POLYSACCHARIDES, THEIR PREPARATION AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
JP2006096668A (en) * | 2002-11-08 | 2006-04-13 | Ono Pharmaceut Co Ltd | Medicine comprising combination of elastase inhibitor with enzyme inhibitor of blood coagulation system and/or fibrinolysis system |
DE10260958A1 (en) * | 2002-12-20 | 2004-07-08 | Sustech Gmbh & Co. Kg | Composite materials made from calcium compounds and polysaccharides containing glucuronic acid and / or iduronic acid |
US7956046B2 (en) | 2003-07-24 | 2011-06-07 | Aventis Pharma S.A. | Oligosaccharide mixtures derived from heparin, preparation thereof and pharmaceutical compositions containing them |
ITMI20031679A1 (en) * | 2003-08-29 | 2005-02-28 | Opocrin Spa | PROCESS FOR THE PRODUCTION OF LOW WEIGHT EPARINES |
EP1582531A1 (en) | 2004-03-24 | 2005-10-05 | Aventis Pharma S.A. | Process for oxidizing unfractionated heparins and detecting presence or absence of glycoserine in heparin and heparin products |
US20050261241A1 (en) | 2004-05-19 | 2005-11-24 | Celsus Biopharmaceuticals, Inc. | Use of dermatan sulfates and/or desulfated heparins to treat or prevent heparinoid-induced autoimmune responses |
EP1792621B1 (en) | 2005-11-30 | 2012-04-04 | Istituto di Ricerche Chimiche e Biochimiche "G. Ronzoni" | Orally administrable heparin derivatives |
ES2340902B1 (en) * | 2008-07-01 | 2011-05-03 | Laboratorios Farmaceuticos Rovi, S.A. | PHARMACEUTICAL COMPOSITION WITH GLYCAMINOGLYGANS AND ITS USE IN THE TREATMENT OF CHRONIC ULCERAS. |
CN103209997B (en) * | 2010-09-14 | 2016-03-16 | 国立大学法人宫崎大学 | high-purity heparin and preparation method thereof |
CA3085285A1 (en) | 2017-12-11 | 2019-06-20 | Biological E Limited | Process for the preparation of low molecular weight heparin |
JP2022540849A (en) | 2019-07-09 | 2022-09-20 | オプティムヴィア、エルエルシー | Method for synthesizing anticoagulant polysaccharide |
CN114072430B (en) | 2020-04-27 | 2023-07-28 | 罗威制药股份有限公司 | Low molecular weight heparin acquisition procedure and low molecular weight heparin obtained |
EP4182452A4 (en) | 2020-07-14 | 2024-07-31 | Optimvia Llc | Methods for synthesizing non-anticoagulant heparan sulfate |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3835112A (en) * | 1970-06-08 | 1974-09-10 | Etude Et D Exploit De Marques | Heparin esters |
CA1136620A (en) * | 1979-01-08 | 1982-11-30 | Ulf P.F. Lindahl | Heparin fragments having selective anticoagulation activity |
-
1980
- 1980-05-14 FR FR8010791A patent/FR2482611B1/en not_active Expired
-
1981
- 1981-05-08 EP EP81400728A patent/EP0040144B1/en not_active Expired
- 1981-05-08 GR GR64889A patent/GR82283B/el unknown
- 1981-05-08 DE DE8181400728T patent/DE3165361D1/en not_active Expired
- 1981-05-11 MA MA19352A patent/MA19143A1/en unknown
- 1981-05-12 PT PT73024A patent/PT73024B/en unknown
- 1981-05-12 HU HU811300A patent/HU188667B/en unknown
- 1981-05-13 KR KR1019810001640A patent/KR840001753B1/en active
- 1981-05-13 DK DK211981A patent/DK168824B1/en not_active IP Right Cessation
- 1981-05-13 NO NO811632A patent/NO156129C/en not_active IP Right Cessation
- 1981-05-13 FI FI811469A patent/FI67865C/en not_active IP Right Cessation
- 1981-05-13 NZ NZ197081A patent/NZ197081A/en unknown
- 1981-05-13 DZ DZ816189A patent/DZ294A1/en active
- 1981-05-13 IE IE1074/81A patent/IE51283B1/en not_active IP Right Cessation
- 1981-05-13 ES ES502199A patent/ES502199A0/en active Granted
- 1981-05-13 IL IL62866A patent/IL62866A/en not_active IP Right Cessation
- 1981-05-13 ZA ZA00813176A patent/ZA813176B/en unknown
- 1981-05-13 AU AU70519/81A patent/AU535791B2/en not_active Expired
- 1981-05-13 AT AT0213681A patent/AT384428B/en not_active IP Right Cessation
- 1981-05-14 IN IN513/CAL/81A patent/IN152828B/en unknown
- 1981-05-14 AR AR285321A patent/AR229510A1/en active
- 1981-05-14 CA CA000377577A patent/CA1181744A/en not_active Expired
- 1981-05-14 JP JP56072858A patent/JPS6051482B2/en not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
EXP | Patent expired |