NO801119L - Fremgangsmaate ved fremstilling av blandede salter av essensielle eller semi-essensielle aminosyrer og nitrogenfrie analoger derav - Google Patents

Fremgangsmaate ved fremstilling av blandede salter av essensielle eller semi-essensielle aminosyrer og nitrogenfrie analoger derav

Info

Publication number
NO801119L
NO801119L NO801119A NO801119A NO801119L NO 801119 L NO801119 L NO 801119L NO 801119 A NO801119 A NO 801119A NO 801119 A NO801119 A NO 801119A NO 801119 L NO801119 L NO 801119L
Authority
NO
Norway
Prior art keywords
essential
semi
procedure
preparation
amino acids
Prior art date
Application number
NO801119A
Other languages
English (en)
Other versions
NO155239B (no
NO155239C (no
Inventor
Mackenzie M D Walser
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Publication of NO801119L publication Critical patent/NO801119L/no
Publication of NO155239B publication Critical patent/NO155239B/no
Publication of NO155239C publication Critical patent/NO155239C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO801119A 1979-04-18 1980-04-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive, blandede salter av essensielle eller semi-essensielle aminosyrer og nitrogenfri analoger derav. NO155239C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/031,274 US4296127A (en) 1979-04-18 1979-04-18 Mixed salts of essential or semi-essential amino acids and nitrogen-free analogs thereof

Publications (3)

Publication Number Publication Date
NO801119L true NO801119L (no) 1980-10-20
NO155239B NO155239B (no) 1986-11-24
NO155239C NO155239C (no) 1987-03-04

Family

ID=21858554

Family Applications (1)

Application Number Title Priority Date Filing Date
NO801119A NO155239C (no) 1979-04-18 1980-04-17 Analogifremgangsmaate ved fremstilling av terapeutisk aktive, blandede salter av essensielle eller semi-essensielle aminosyrer og nitrogenfri analoger derav.

Country Status (16)

Country Link
US (1) US4296127A (no)
JP (1) JPS6024094B2 (no)
BE (1) BE882833A (no)
CA (1) CA1139768A (no)
DE (1) DE3015076A1 (no)
DK (1) DK159147C (no)
ES (1) ES8102804A1 (no)
FI (1) FI70206C (no)
FR (1) FR2454434A1 (no)
GB (1) GB2048867B (no)
IE (1) IE49586B1 (no)
IT (1) IT1141482B (no)
LU (1) LU82369A1 (no)
NL (1) NL191583C (no)
NO (1) NO155239C (no)
SE (1) SE460902B (no)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61501558A (ja) * 1984-01-16 1986-07-31 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテッド 中および長鎖トリグリセライドの非経口栄養補給
DE3438455A1 (de) * 1984-10-19 1986-06-26 Institut Dr. Ziegler, Bettingen L-lysin- und l-histidinpyruvat
US4677121A (en) * 1985-01-22 1987-06-30 The Johns Hopkins University Method of inhibiting muscle protein degradation
US4752619A (en) * 1985-12-23 1988-06-21 The Johns Hopkins University Nutritional supplement for treatment of uremia
US4871552A (en) * 1986-09-25 1989-10-03 W. R. Grace & Co.-Conn. Hydantoins as animal food supplements
US4744990A (en) * 1986-09-25 1988-05-17 W. R. Grace & Co. Hydantoins as animal food supplements
FR2615734B1 (fr) * 1987-05-27 1989-12-01 Synthelabo Compositions pharmaceutiques contenant un melange de sels de cetoacides et d'amino-acides utiles pour le traitement de l'uremie
FR2618331B1 (fr) * 1987-07-23 1991-10-04 Synthelabo Compositions pharmaceutiques utiles pour le traitement de l'uremie
JP2522034B2 (ja) * 1988-12-27 1996-08-07 味の素株式会社 α−ケト酸・アミノ酸塩化合物及びその製造方法
US4957938A (en) * 1989-06-21 1990-09-18 Abbott Laboratories Nutritional formulation for the treatment of renal disease
DE3936319C3 (de) * 1989-11-01 1997-05-07 Bartz Volker Phosphatbinder zur oralen Verabreichung
DE3940052A1 (de) * 1989-12-04 1991-06-06 Nephro Medica Pharma Dialysier- und spuelloesung zur intraperitonealen verabreichung
DE3943424A1 (de) * 1989-12-30 1991-07-04 Nephro Medica Pharma Infusions- und injektionsloesung zur intravenoesen verabreichung
US5234696A (en) * 1991-12-27 1993-08-10 Abbott Laboratories Method of producing tablets, tablets produced thereby, and method of treatment using same
US5256697A (en) * 1992-04-16 1993-10-26 Abbott Laboratories Method of administering pyruvate and methods of synthesizing pyruvate precursors
US5276018A (en) * 1992-07-17 1994-01-04 Brigham And Women's Hospital Composition comprising amino acids and methods for decreasing muscle breakdown
US6797289B2 (en) * 1998-02-13 2004-09-28 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US20070141181A1 (en) 1998-02-13 2007-06-21 Nutramax Laboratories, Inc. Use of anabolic agents, anti-catabolic agents, antioxidant agents, and analgesics for protection, treatment and repair of connective tissues in humans and animals
US20010000472A1 (en) * 1998-02-27 2001-04-26 Nutramax Laboratories, Inc. L-ergothioneine, milk thistle, and s-adenosylmethionine for the prevention, treatment and repair of liver damage
JP2002504514A (ja) 1998-02-27 2002-02-12 ニュートラマックス ラボラトリーズ,インコーポレイテッド 肝臓傷害の予防、治療及び修復のためのl−エルゴチオネイン、ノゲシ及びs−アデノシルメテオニン
US8680329B2 (en) * 2010-10-13 2014-03-25 Tianjin Tiancheng Pharmaceutical Co., Ltd. (China) Process for preparation of α-ketoglutaric acid
US8754256B2 (en) * 2010-10-13 2014-06-17 Tianjin Tiancheng Pharmaceutical Co., Ltd. (China) Process for preparation of L-Arginine α-ketoglutarate 1:1 and 2:1
US20140187815A1 (en) * 2012-12-28 2014-07-03 Guoji Zhang Process for preparation of l-arginine alpha-ketoglutarate 1:1 and 2:1
CN113677787A (zh) * 2019-04-11 2021-11-19 默克专利股份公司 包含酮酸的细胞培养基

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2457820A (en) * 1945-12-27 1949-01-04 Merck & Co Inc Amino acid solution and process for preparing the same
US3441650A (en) * 1965-07-23 1969-04-29 Lab Jacques Logeais Sa Therapy of ammonical intoxications by di-l-ornithine alpha-ketoglutarate
US3764703A (en) * 1969-11-07 1973-10-09 Astra Ab Amino acid mixture for use in treatment of uremic conditions
DE2335215B2 (de) * 1972-07-13 1979-04-05 The Johns Hopkins University, Baltimore, Md. (V.St.A.) Verwendung einer Mischung bei der Bekämpfung von zur Urämie führenden Nierenerkrankungen
GB1442154A (en) * 1973-04-30 1976-07-07 Walser M Composition for promotion of protein synthesis and suppression of urea formation in the body
GB1511302A (en) * 1974-04-15 1978-05-17 Univ Johns Hopkins Pharmaceutical compositions comprising amino acid analogues
US4100161A (en) * 1974-04-15 1978-07-11 The Johns Hopkins University Promotion of protein synthesis and suppression of urea formation in the body by keto analogs of essential amino acids
FR2315916A2 (fr) * 1976-03-23 1977-01-28 Univ Johns Hopkins Melanges therapeutiques comprenant des analogues alpha hydroxy acides d'acides amines essentiels et leur administration a l'homme en vue de l'amelioration de la synthese proteique et la suppression de la formation d'uree
DE2759133A1 (de) * 1976-12-31 1978-07-13 Carmelo Prof Giordano Gemisch essentieller aminosaeuren und/oder analoger ketosaeuren und verwendung derselben diaetzusatz bei niereninsuffizienz
US4228099A (en) * 1978-03-17 1980-10-14 The Johns Hopkins University Ornithine and arginine salts of branched chain keto acids and uses in treatment of hepatic and renal disorders

Also Published As

Publication number Publication date
IE800781L (en) 1980-10-19
DE3015076A1 (de) 1980-10-30
NO155239B (no) 1986-11-24
FR2454434B1 (no) 1984-02-24
NL191583C (nl) 1995-10-03
BE882833A (fr) 1980-08-18
DK159147C (da) 1991-02-11
ES490649A0 (es) 1981-02-16
CA1139768A (en) 1983-01-18
NL8002297A (nl) 1980-10-21
SE8002900L (sv) 1980-12-12
DK159147B (da) 1990-09-10
FI70206B (fi) 1986-02-28
JPS6024094B2 (ja) 1985-06-11
US4296127A (en) 1981-10-20
SE460902B (sv) 1989-12-04
GB2048867A (en) 1980-12-17
NL191583B (nl) 1995-06-01
DK163180A (da) 1980-10-19
NO155239C (no) 1987-03-04
DE3015076C2 (no) 1988-01-21
FI801225A (fi) 1980-10-19
ES8102804A1 (es) 1981-02-16
LU82369A1 (fr) 1980-07-31
JPS5653641A (en) 1981-05-13
FI70206C (fi) 1986-09-15
FR2454434A1 (fr) 1980-11-14
GB2048867B (en) 1983-03-16
IT1141482B (it) 1986-10-01
IE49586B1 (en) 1985-10-30
IT8021498A0 (it) 1980-04-18

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