NO781076L - Antibiotikum ps-5 og derivater av dette med beta-laktamasehemmende aktivitet samt fremgangsmaate for dets fremstilling - Google Patents
Antibiotikum ps-5 og derivater av dette med beta-laktamasehemmende aktivitet samt fremgangsmaate for dets fremstillingInfo
- Publication number
- NO781076L NO781076L NO781076A NO781076A NO781076L NO 781076 L NO781076 L NO 781076L NO 781076 A NO781076 A NO 781076A NO 781076 A NO781076 A NO 781076A NO 781076 L NO781076 L NO 781076L
- Authority
- NO
- Norway
- Prior art keywords
- antibiotic
- compound
- hydrogen
- formula
- lactamase
- Prior art date
Links
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- 238000000034 method Methods 0.000 title claims description 44
- 108090000204 Dipeptidase 1 Proteins 0.000 title claims description 28
- 102000006635 beta-lactamase Human genes 0.000 title claims description 28
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- 238000002360 preparation method Methods 0.000 title description 32
- 230000002401 inhibitory effect Effects 0.000 title description 18
- -1 trimethylmethyl Chemical group 0.000 claims description 95
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- 150000001875 compounds Chemical class 0.000 claims description 53
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical class N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 claims description 46
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- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 claims description 22
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- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims description 9
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- 229930186147 Cephalosporin Chemical class 0.000 claims description 8
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP52035375A JPS604719B2 (ja) | 1977-03-31 | 1977-03-31 | β‐ラクタマーゼ阻害活性を有する抗生物質PS―5の製造方法 |
JP9465177A JPS5430195A (en) | 1977-08-09 | 1977-08-09 | Antibiotic substance ps-5 having beta-lactamase inhibiting activity, its derivative and their preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
NO781076L true NO781076L (no) | 1978-10-03 |
Family
ID=26374352
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO781076A NO781076L (no) | 1977-03-31 | 1978-03-29 | Antibiotikum ps-5 og derivater av dette med beta-laktamasehemmende aktivitet samt fremgangsmaate for dets fremstilling |
Country Status (21)
Country | Link |
---|---|
US (1) | US4318916A (fr) |
AR (1) | AR219738A1 (fr) |
AT (1) | AT362059B (fr) |
AU (1) | AU518781B2 (fr) |
CA (1) | CA1123767A (fr) |
CH (1) | CH643262A5 (fr) |
DE (1) | DE2813922A1 (fr) |
DK (1) | DK144098C (fr) |
FI (1) | FI59813C (fr) |
FR (1) | FR2408608B1 (fr) |
GB (1) | GB1598062A (fr) |
GR (1) | GR62185B (fr) |
IE (1) | IE46369B1 (fr) |
IL (1) | IL54118A (fr) |
IT (1) | IT1113066B (fr) |
LU (1) | LU79351A1 (fr) |
NL (1) | NL7802976A (fr) |
NO (1) | NO781076L (fr) |
NZ (1) | NZ186830A (fr) |
PT (1) | PT67848B (fr) |
SE (1) | SE7803623L (fr) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0011173B1 (fr) | 1978-11-01 | 1983-05-11 | Sanraku-Ocean Co., Ltd. | Procédé pour la production de composés antibiotiques bêta-lactame |
DE3146190A1 (de) * | 1981-11-21 | 1983-06-16 | Hoechst Ag, 6230 Frankfurt | Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen |
US5650290A (en) * | 1994-04-01 | 1997-07-22 | Hach Company | Method & Medium for use in detecting E. coli and total coliforms |
US5849515A (en) * | 1994-04-01 | 1998-12-15 | Hach Company | Method and medium for use in detecting E. coli and total coliforms |
KR100379075B1 (en) * | 2002-03-07 | 2003-04-08 | Jinis Biopharmaceuticals Co | Method for producing low cholesterol animal food product and food product therefrom |
FI20205368A1 (en) * | 2020-04-07 | 2021-10-08 | Aalto Univ Foundation Sr | FORMULATION |
CN111826334A (zh) * | 2020-07-24 | 2020-10-27 | 暨南大学 | 一种超长大肠杆菌及其制备方法与应用 |
CN113960188B (zh) * | 2021-09-09 | 2024-01-26 | 中车青岛四方机车车辆股份有限公司 | 高效液相色谱-串联质谱法测定样品中的4,4-二(二甲氨基)-4-甲氨基三苯甲醇 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3928569A (en) * | 1972-08-09 | 1975-12-23 | Microbial Chem Res Found | Two substances inhibiting beta-lactamase and their production |
GB1467413A (en) * | 1974-03-28 | 1977-03-16 | Beecham Group Ltd | Antibiotics |
US3950357A (en) * | 1974-11-25 | 1976-04-13 | Merck & Co., Inc. | Antibiotics |
US4162324A (en) * | 1975-11-21 | 1979-07-24 | Merck & Co., Inc. | Antibiotics 890A1 and 890A3 |
US4165379A (en) * | 1975-11-21 | 1979-08-21 | Merck & Co., Inc. | N-acetyl thienamycin |
DK145504C (da) * | 1976-04-28 | 1983-04-25 | Merck & Co Inc | Fremgangsmaade til fremstilling af det antibiotiske stof 890a2og/eller det antibiotiske stof 890a5 og farmaceutisk acceptable salte deraf |
NL7802826A (nl) * | 1977-04-08 | 1978-10-10 | Merck & Co Inc | Thienamycinederivaat, werkwijze voor het bereiden daarvan, alsmede farmaceutische preparaten. |
US4162323A (en) * | 1977-04-18 | 1979-07-24 | Merck & Co., Inc. | Antibiotic N-acetyl-dehydro-thienamycin |
US4235922A (en) * | 1979-06-15 | 1980-11-25 | Merck & Co., Inc. | 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid |
-
1978
- 1978-02-15 GR GR55463A patent/GR62185B/el unknown
- 1978-02-23 IL IL54118A patent/IL54118A/xx unknown
- 1978-02-28 FI FI780671A patent/FI59813C/fi not_active IP Right Cessation
- 1978-03-02 US US05/882,730 patent/US4318916A/en not_active Expired - Lifetime
- 1978-03-09 GB GB9338/78A patent/GB1598062A/en not_active Expired
- 1978-03-20 NL NL7802976A patent/NL7802976A/xx not_active Application Discontinuation
- 1978-03-29 AR AR271592A patent/AR219738A1/es active
- 1978-03-29 NO NO781076A patent/NO781076L/no unknown
- 1978-03-30 AT AT224578A patent/AT362059B/de not_active IP Right Cessation
- 1978-03-30 IT IT21748/78A patent/IT1113066B/it active
- 1978-03-30 CA CA300,097A patent/CA1123767A/fr not_active Expired
- 1978-03-30 NZ NZ186830A patent/NZ186830A/xx unknown
- 1978-03-30 IE IE638/78A patent/IE46369B1/en unknown
- 1978-03-30 CH CH340678A patent/CH643262A5/de not_active IP Right Cessation
- 1978-03-30 SE SE7803623A patent/SE7803623L/xx unknown
- 1978-03-30 AU AU34592/78A patent/AU518781B2/en not_active Expired
- 1978-03-30 PT PT67848A patent/PT67848B/pt unknown
- 1978-03-31 LU LU79351A patent/LU79351A1/fr unknown
- 1978-03-31 DK DK143678A patent/DK144098C/da not_active IP Right Cessation
- 1978-03-31 FR FR7809644A patent/FR2408608B1/fr not_active Expired
- 1978-03-31 DE DE19782813922 patent/DE2813922A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
FI780671A (fi) | 1978-10-01 |
GR62185B (en) | 1979-03-02 |
CA1123767A (fr) | 1982-05-18 |
DK144098C (da) | 1982-06-01 |
NZ186830A (en) | 1981-12-15 |
US4318916A (en) | 1982-03-09 |
IE46369B1 (en) | 1983-05-18 |
FI59813C (fi) | 1981-10-12 |
IL54118A (en) | 1981-09-13 |
AR219738A1 (es) | 1980-09-15 |
IT1113066B (it) | 1986-01-20 |
CH643262A5 (de) | 1984-05-30 |
PT67848A (en) | 1978-04-01 |
FR2408608A1 (fr) | 1979-06-08 |
IT7821748A0 (it) | 1978-03-30 |
PT67848B (en) | 1979-09-28 |
NL7802976A (nl) | 1978-10-03 |
LU79351A1 (fr) | 1979-03-26 |
FI59813B (fi) | 1981-06-30 |
FR2408608B1 (fr) | 1986-05-16 |
AU3459278A (en) | 1979-10-04 |
DE2813922A1 (de) | 1978-10-19 |
AT362059B (de) | 1981-04-27 |
ATA224578A (de) | 1980-09-15 |
DK144098B (da) | 1981-12-07 |
IE780638L (en) | 1978-09-30 |
AU518781B2 (en) | 1981-10-22 |
GB1598062A (en) | 1981-09-16 |
DK143678A (da) | 1978-10-01 |
SE7803623L (sv) | 1978-11-17 |
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