PT67848B - Process for preparing a novel antibiotic and its derivatives having beta-lactamase inihbitory activity - Google Patents

Process for preparing a novel antibiotic and its derivatives having beta-lactamase inihbitory activity

Info

Publication number
PT67848B
PT67848B PT67848A PT6784878A PT67848B PT 67848 B PT67848 B PT 67848B PT 67848 A PT67848 A PT 67848A PT 6784878 A PT6784878 A PT 6784878A PT 67848 B PT67848 B PT 67848B
Authority
PT
Portugal
Prior art keywords
inihbitory
lactamase
beta
derivatives
preparing
Prior art date
Application number
PT67848A
Other languages
English (en)
Other versions
PT67848A (en
Inventor
Kazuhiko Okamura
Yasuo Fukagawa
Shoji Hirata
Joseph Lein
Yasushi Okumura
Tomoyuki Ishikura
Yasutaka Shimauchi
Kageaki Kauno
Original Assignee
Sanraku Ocean Co
Panlabs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP52035375A external-priority patent/JPS604719B2/ja
Priority claimed from JP9465177A external-priority patent/JPS5430195A/ja
Application filed by Sanraku Ocean Co, Panlabs Inc filed Critical Sanraku Ocean Co
Publication of PT67848A publication Critical patent/PT67848A/pt
Publication of PT67848B publication Critical patent/PT67848B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cephalosporin Compounds (AREA)
PT67848A 1977-03-31 1978-03-30 Process for preparing a novel antibiotic and its derivatives having beta-lactamase inihbitory activity PT67848B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP52035375A JPS604719B2 (ja) 1977-03-31 1977-03-31 β‐ラクタマーゼ阻害活性を有する抗生物質ＰＳ―５の製造方法
JP9465177A JPS5430195A (en) 1977-08-09 1977-08-09 Antibiotic substance ps-5 having beta-lactamase inhibiting activity, its derivative and their preparation

Publications (2)

Publication Number Publication Date
PT67848A PT67848A (en) 1978-04-01
PT67848B true PT67848B (en) 1979-09-28

Family

ID=26374352

Family Applications (1)

Application Number Title Priority Date Filing Date
PT67848A PT67848B (en) 1977-03-31 1978-03-30 Process for preparing a novel antibiotic and its derivatives having beta-lactamase inihbitory activity

Country Status (21)

Country Link
US (1) US4318916A (pt)
AR (1) AR219738A1 (pt)
AT (1) AT362059B (pt)
AU (1) AU518781B2 (pt)
CA (1) CA1123767A (pt)
CH (1) CH643262A5 (pt)
DE (1) DE2813922A1 (pt)
DK (1) DK144098C (pt)
FI (1) FI59813C (pt)
FR (1) FR2408608B1 (pt)
GB (1) GB1598062A (pt)
GR (1) GR62185B (pt)
IE (1) IE46369B1 (pt)
IL (1) IL54118A (pt)
IT (1) IT1113066B (pt)
LU (1) LU79351A1 (pt)
NL (1) NL7802976A (pt)
NO (1) NO781076L (pt)
NZ (1) NZ186830A (pt)
PT (1) PT67848B (pt)
SE (1) SE7803623L (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011173B1 (en) 1978-11-01 1983-05-11 Sanraku-Ocean Co., Ltd. Process for producing antibiotic beta-lactam compounds
DE3146190A1 (de) * 1981-11-21 1983-06-16 Hoechst Ag, 6230 Frankfurt Isolierung von chemisch instabilen antibiotika aus fermentationsloesungen
US5650290A (en) * 1994-04-01 1997-07-22 Hach Company Method & Medium for use in detecting E. coli and total coliforms
US5849515A (en) * 1994-04-01 1998-12-15 Hach Company Method and medium for use in detecting E. coli and total coliforms
KR100379075B1 (en) * 2002-03-07 2003-04-08 Jinis Biopharmaceuticals Co Method for producing low cholesterol animal food product and food product therefrom
FI20205368A1 (en) * 2020-04-07 2021-10-08 Aalto Univ Foundation Sr FORMULATION
CN111826334A (zh) * 2020-07-24 2020-10-27 暨南大学 一种超长大肠杆菌及其制备方法与应用
CN113960188B (zh) * 2021-09-09 2024-01-26 中车青岛四方机车车辆股份有限公司 高效液相色谱-串联质谱法测定样品中的4,4-二(二甲氨基)-4-甲氨基三苯甲醇

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3928569A (en) * 1972-08-09 1975-12-23 Microbial Chem Res Found Two substances inhibiting beta-lactamase and their production
GB1467413A (en) * 1974-03-28 1977-03-16 Beecham Group Ltd Antibiotics
US3950357A (en) * 1974-11-25 1976-04-13 Merck & Co., Inc. Antibiotics
US4165379A (en) * 1975-11-21 1979-08-21 Merck & Co., Inc. N-acetyl thienamycin
US4162324A (en) * 1975-11-21 1979-07-24 Merck & Co., Inc. Antibiotics 890A1 and 890A3
NL7704040A (nl) * 1976-04-28 1977-11-01 Merck & Co Inc Werkwijze voor het bereiden van nieuwe anti- biotica.
NL7802826A (nl) * 1977-04-08 1978-10-10 Merck & Co Inc Thienamycinederivaat, werkwijze voor het bereiden daarvan, alsmede farmaceutische preparaten.
US4162323A (en) * 1977-04-18 1979-07-24 Merck & Co., Inc. Antibiotic N-acetyl-dehydro-thienamycin
US4235922A (en) * 1979-06-15 1980-11-25 Merck & Co., Inc. 3-(2-Aminoethylthio)-6-ethyl-7-oxo-1-azabicyclo [3.2.0]hept-2-ene-2-carboxylic acid

Also Published As

Publication number Publication date
IE46369B1 (en) 1983-05-18
US4318916A (en) 1982-03-09
FR2408608A1 (fr) 1979-06-08
IT7821748A0 (it) 1978-03-30
IE780638L (en) 1978-09-30
GR62185B (en) 1979-03-02
IT1113066B (it) 1986-01-20
SE7803623L (sv) 1978-11-17
DE2813922A1 (de) 1978-10-19
PT67848A (en) 1978-04-01
AU518781B2 (en) 1981-10-22
NL7802976A (nl) 1978-10-03
DK144098C (da) 1982-06-01
DK144098B (da) 1981-12-07
AR219738A1 (es) 1980-09-15
DK143678A (da) 1978-10-01
FI780671A (fi) 1978-10-01
NO781076L (no) 1978-10-03
IL54118A (en) 1981-09-13
LU79351A1 (fr) 1979-03-26
FI59813B (fi) 1981-06-30
FI59813C (fi) 1981-10-12
AU3459278A (en) 1979-10-04
GB1598062A (en) 1981-09-16
AT362059B (de) 1981-04-27
ATA224578A (de) 1980-09-15
CA1123767A (en) 1982-05-18
NZ186830A (en) 1981-12-15
FR2408608B1 (fr) 1986-05-16
CH643262A5 (de) 1984-05-30

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