NO772473L - Fremgangsm}te ved fremstilling av nye thieno (2,3-c) og (3,2-c) pyridiner - Google Patents
Fremgangsm}te ved fremstilling av nye thieno (2,3-c) og (3,2-c) pyridinerInfo
- Publication number
- NO772473L NO772473L NO772473A NO772473A NO772473L NO 772473 L NO772473 L NO 772473L NO 772473 A NO772473 A NO 772473A NO 772473 A NO772473 A NO 772473A NO 772473 L NO772473 L NO 772473L
- Authority
- NO
- Norway
- Prior art keywords
- formula
- compound
- thieno
- pyridine
- tetrahydro
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 38
- 238000002360 preparation method Methods 0.000 title claims description 14
- RQMWVVBHJMUJNZ-UHFFFAOYSA-N 4-chloropyridin-2-amine Chemical compound NC1=CC(Cl)=CC=N1 RQMWVVBHJMUJNZ-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 claims description 21
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 9
- 125000005843 halogen group Chemical group 0.000 claims description 8
- -1 hydroxy, nitro, amino Chemical group 0.000 claims description 7
- 125000000217 alkyl group Chemical group 0.000 claims description 6
- ULSIYEODSMZIPX-UHFFFAOYSA-N phenylethanolamine Chemical compound NCC(O)C1=CC=CC=C1 ULSIYEODSMZIPX-UHFFFAOYSA-N 0.000 claims description 6
- 125000003545 alkoxy group Chemical group 0.000 claims description 5
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- 125000004453 alkoxycarbonyl group Chemical group 0.000 claims description 2
- 125000003710 aryl alkyl group Chemical group 0.000 claims description 2
- 125000003118 aryl group Chemical group 0.000 claims description 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 2
- 150000003839 salts Chemical class 0.000 claims description 2
- 125000001424 substituent group Chemical group 0.000 claims description 2
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 claims description 2
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- 239000002253 acid Substances 0.000 claims 1
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- GDQBPBMIAFIRIU-UHFFFAOYSA-N thieno[2,3-c]pyridine Chemical compound C1=NC=C2SC=CC2=C1 GDQBPBMIAFIRIU-UHFFFAOYSA-N 0.000 description 24
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- PYEZYNAHBMWJFR-UHFFFAOYSA-N thieno[3,2-c]pyridine Chemical compound N1=CC=C2S[C]=CC2=C1 PYEZYNAHBMWJFR-UHFFFAOYSA-N 0.000 description 16
- 239000000203 mixture Substances 0.000 description 11
- 238000006243 chemical reaction Methods 0.000 description 10
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 10
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- 238000003756 stirring Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 238000001356 surgical procedure Methods 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000006188 syrup Substances 0.000 description 1
- 235000020357 syrup Nutrition 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- DBDCNCCRPKTRSD-UHFFFAOYSA-N thieno[3,2-b]pyridine Chemical class C1=CC=C2SC=CC2=N1 DBDCNCCRPKTRSD-UHFFFAOYSA-N 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
- 150000003626 triacylglycerols Chemical class 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- 229940045860 white wax Drugs 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7621440A FR2358150A1 (fr) | 1976-07-13 | 1976-07-13 | Nouvelles thieno (2,3-c) et (3,2-c) pyridines, leur procede de preparation et leur application |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO772473L true NO772473L (no) | 1978-01-16 |
Family
ID=9175680
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO772473A NO772473L (no) | 1976-07-13 | 1977-07-12 | Fremgangsm}te ved fremstilling av nye thieno (2,3-c) og (3,2-c) pyridiner |
Country Status (32)
| Country | Link |
|---|---|
| US (1) | US4104390A (es) |
| JP (1) | JPS6019757B2 (es) |
| AR (1) | AR220897A1 (es) |
| AT (1) | AT357160B (es) |
| AU (1) | AU511878B2 (es) |
| BE (1) | BE856732A (es) |
| CA (1) | CA1106378A (es) |
| CH (1) | CH624409A5 (es) |
| DD (1) | DD131559A5 (es) |
| DE (1) | DE2730832A1 (es) |
| DK (1) | DK315477A (es) |
| ES (1) | ES460034A1 (es) |
| FI (1) | FI772172A (es) |
| FR (1) | FR2358150A1 (es) |
| GB (1) | GB1578542A (es) |
| GR (1) | GR63653B (es) |
| HU (1) | HU173504B (es) |
| IE (1) | IE45149B1 (es) |
| IL (1) | IL52370A (es) |
| LU (1) | LU77439A1 (es) |
| MX (1) | MX4547E (es) |
| NL (1) | NL7706987A (es) |
| NO (1) | NO772473L (es) |
| NZ (1) | NZ184605A (es) |
| PH (1) | PH13101A (es) |
| PL (1) | PL102917B1 (es) |
| PT (1) | PT66769B (es) |
| RO (1) | RO72103A (es) |
| SE (1) | SE432766B (es) |
| SU (1) | SU668605A3 (es) |
| YU (1) | YU40673B (es) |
| ZA (1) | ZA773808B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2423494A1 (fr) * | 1977-06-02 | 1979-11-16 | Parcor | Benzo (b) thieno pyridines, leur procede de preparation et leurs applications therapeutiques |
| AT368504B (de) * | 1977-10-15 | 1982-10-25 | Boehringer Sohn Ingelheim | Verfahren zur herstellung neuer 4-phenyl-thieno- (2,3-c)-piperidine |
| US4282227A (en) * | 1980-05-22 | 1981-08-04 | Smithkline Corporation | Renal vasodilating 3,4-dihydroxyphenyltetrahydrothienopyridines |
| DE3175410D1 (en) * | 1980-07-29 | 1986-11-06 | Sanofi Sa | Acid stabilized compositions of thieno-pyridine derived compounds and process for preventing degradation of such compounds |
| US4321266A (en) * | 1980-10-06 | 1982-03-23 | Sanofi | 5-o-Cyanobenzyl-4,5,6,7-tetrahydrothieno [3,2-C] pyridine |
| DD210278A5 (de) * | 1982-03-05 | 1984-06-06 | Boehringer Ingelheim Kg | Verfahren zur herstellung neuer basisch substituierter 4-phenyl-4,5,6,7-tetrahydro-thieno-(2,3-c)pyridine |
| IL71661A0 (en) * | 1983-04-27 | 1984-07-31 | Boehringer Ingelheim Kg | 4-phenyl-tetrahydro-furano-pyridines,their preparation and pharmaceutical compositions containing them |
| US4572911A (en) * | 1984-08-02 | 1986-02-25 | Mcneilab, Inc. | Hexahydroindolinzine compounds, pharmaceutical compositions and methods and intermediates |
| GB8429087D0 (en) * | 1984-11-16 | 1984-12-27 | Scras | Thienopyridine derivatives |
| US4775757A (en) * | 1986-09-22 | 1988-10-04 | Ortho Pharmaceutical Corporation | Thienopyridines useful as cardiovascular agents |
| US4876261A (en) * | 1987-03-27 | 1989-10-24 | Akihiro Tanaka | Substituted tetrahydroisoquinoline compounds and composition containing them |
| HUP0400644A3 (en) * | 2000-12-25 | 2009-06-29 | Ube Industries | Pharmaceutical compositions containing aspirin |
| US9137912B1 (en) * | 2013-02-05 | 2015-09-15 | Htc Corporation | Casing of electronic device and method of manufacturing the same |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3632592A (en) * | 1969-02-03 | 1972-01-04 | Yoshitomi Pharmaceutical | Certain substituted thieno(2 3-c)4 5 6 7-tetrahydro pyridines |
-
1976
- 1976-07-13 FR FR7621440A patent/FR2358150A1/fr active Granted
-
1977
- 1977-05-27 LU LU77439A patent/LU77439A1/xx unknown
- 1977-05-27 CH CH653477A patent/CH624409A5/fr not_active IP Right Cessation
- 1977-06-13 YU YU1456/77A patent/YU40673B/xx unknown
- 1977-06-21 IE IE1263/77A patent/IE45149B1/en unknown
- 1977-06-21 US US05/808,694 patent/US4104390A/en not_active Expired - Lifetime
- 1977-06-22 IL IL52370A patent/IL52370A/xx unknown
- 1977-06-23 NL NL7706987A patent/NL7706987A/xx not_active Application Discontinuation
- 1977-06-23 ES ES460034A patent/ES460034A1/es not_active Expired
- 1977-06-24 ZA ZA00773808A patent/ZA773808B/xx unknown
- 1977-06-30 CA CA281,824A patent/CA1106378A/en not_active Expired
- 1977-07-02 RO RO7790903A patent/RO72103A/ro unknown
- 1977-07-06 PT PT66769A patent/PT66769B/pt unknown
- 1977-07-07 AR AR268365A patent/AR220897A1/es active
- 1977-07-07 AT AT487977A patent/AT357160B/de not_active IP Right Cessation
- 1977-07-08 NZ NZ184605A patent/NZ184605A/xx unknown
- 1977-07-08 GR GR53920A patent/GR63653B/el unknown
- 1977-07-08 DE DE19772730832 patent/DE2730832A1/de not_active Withdrawn
- 1977-07-11 MX MX775886U patent/MX4547E/es unknown
- 1977-07-11 SE SE7708029A patent/SE432766B/xx not_active IP Right Cessation
- 1977-07-11 DD DD7700199989A patent/DD131559A5/xx unknown
- 1977-07-12 PH PH19985A patent/PH13101A/en unknown
- 1977-07-12 PL PL1977199562A patent/PL102917B1/pl unknown
- 1977-07-12 DK DK315477A patent/DK315477A/da unknown
- 1977-07-12 NO NO772473A patent/NO772473L/no unknown
- 1977-07-12 GB GB29233/77A patent/GB1578542A/en not_active Expired
- 1977-07-12 FI FI772172A patent/FI772172A/fi not_active Application Discontinuation
- 1977-07-12 BE BE179275A patent/BE856732A/xx not_active IP Right Cessation
- 1977-07-13 AU AU26993/77A patent/AU511878B2/en not_active Expired
- 1977-07-13 SU SU772501203A patent/SU668605A3/ru active
- 1977-07-13 JP JP52083994A patent/JPS6019757B2/ja not_active Expired
- 1977-07-13 HU HU77PA1291A patent/HU173504B/hu unknown
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