NO334788B2 - Fremgangsmåte for behandling av søvnløshet - Google Patents

Fremgangsmåte for behandling av søvnløshet

Info

Publication number
NO334788B2
NO334788B2 NO20040087A NO20040087A NO334788B2 NO 334788 B2 NO334788 B2 NO 334788B2 NO 20040087 A NO20040087 A NO 20040087A NO 20040087 A NO20040087 A NO 20040087A NO 334788 B2 NO334788 B2 NO 334788B2
Authority
NO
Norway
Prior art keywords
procedure
treating insomnia
insomnia
treating
Prior art date
Application number
NO20040087A
Other languages
English (en)
Norwegian (no)
Other versions
NO20040087L (no
NO334788B1 (no
Inventor
Nava Zisapel
Original Assignee
Neurim Pharmaceuticals 1991 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO334788(B2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharmaceuticals 1991 Ltd filed Critical Neurim Pharmaceuticals 1991 Ltd
Publication of NO20040087L publication Critical patent/NO20040087L/no
Publication of NO334788B1 publication Critical patent/NO334788B1/no
Publication of NO334788B2 publication Critical patent/NO334788B2/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
NO20040087A 2001-08-14 2004-01-09 Fremgangsmåte for behandling av søvnløshet NO334788B2 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
PCT/IL2002/000662 WO2003015690A2 (en) 2001-08-14 2002-08-12 Method for treating primary insomnia

Publications (3)

Publication Number Publication Date
NO20040087L NO20040087L (no) 2004-02-19
NO334788B1 NO334788B1 (no) 2014-05-26
NO334788B2 true NO334788B2 (no) 2014-05-26

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040087A NO334788B2 (no) 2001-08-14 2004-01-09 Fremgangsmåte for behandling av søvnløshet

Country Status (35)

Country Link
US (1) US8962024B2 (OSRAM)
EP (2) EP3103443B1 (OSRAM)
JP (1) JP2005501095A (OSRAM)
KR (1) KR20040032917A (OSRAM)
CN (1) CN100453078C (OSRAM)
AR (1) AR034975A1 (OSRAM)
AU (1) AU2002326114C1 (OSRAM)
BR (1) BR0211855A (OSRAM)
CA (1) CA2454699C (OSRAM)
CL (1) CL2002001701A1 (OSRAM)
CR (1) CR7271A (OSRAM)
CY (2) CY1118924T1 (OSRAM)
DK (2) DK1441702T3 (OSRAM)
EA (1) EA200400302A1 (OSRAM)
ES (2) ES2626591T3 (OSRAM)
GT (1) GT200200164A (OSRAM)
HU (1) HU230786B1 (OSRAM)
IL (1) IL144900A (OSRAM)
IS (1) IS3004B (OSRAM)
JO (1) JO3446B1 (OSRAM)
LT (1) LT1441702T (OSRAM)
MX (1) MXPA04001372A (OSRAM)
NO (1) NO334788B2 (OSRAM)
NZ (1) NZ531318A (OSRAM)
PA (1) PA8552301A1 (OSRAM)
PE (1) PE20030331A1 (OSRAM)
PL (1) PL367872A1 (OSRAM)
PT (2) PT3103443T (OSRAM)
PY (1) PY0218122A (OSRAM)
RU (1) RU2560840C2 (OSRAM)
SI (1) SI1441702T1 (OSRAM)
UA (1) UA87262C2 (OSRAM)
UY (1) UY27401A1 (OSRAM)
WO (1) WO2003015690A2 (OSRAM)
ZA (1) ZA200402005B (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
US8940326B2 (en) 2007-03-19 2015-01-27 Vita Sciences Llc Transdermal patch and method for delivery of vitamin B12
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) * 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
MX386987B (es) 2016-10-31 2025-03-19 Neurim Pharma 1991 Mini-tabletas de melatonina y métodos de fabricación de las mismas.
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0513702A2 (en) * 1991-05-13 1992-11-19 I.F.L.O. ISTITUTO FARMACOLOGICO LOMBARDO S.A.S. di Giorgio & Aldo Laguzzi & C. Melatonin derivaties for use in the therapy of sleep disorders and in pre-anaesthetic medication
EP0724878A2 (en) * 1995-02-01 1996-08-07 Neurim Pharmaceuticals (1991) Limited Use of melatonin for treating patients suffering from drug dependencies
US5707652A (en) * 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
NO981489L (no) * 1995-10-03 1998-05-22 Interneuron Pharma Blandinger av melatonin og analgetika samt anvendelser derav

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US3048581A (en) 1960-04-25 1962-08-07 Olin Mathieson Acetals and ketals of 16, 17-dihydroxy steroids
US3749712A (en) 1970-09-25 1973-07-31 Sigma Tau Ind Farmaceuti Triamcinolone acetonide esters and process for their preparation
SE378110B (OSRAM) 1972-05-19 1975-08-18 Bofors Ab
US3996359A (en) 1972-05-19 1976-12-07 Ab Bofors Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
SE378109B (OSRAM) 1972-05-19 1975-08-18 Bofors Ab
JPS6045513A (ja) * 1983-05-18 1985-03-12 モナシユ　ユニバ−シテイ 身体行動および機能の日周期の不調を軽減する薬剤
DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
US5151446A (en) 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
FR2658818B1 (fr) 1990-02-27 1993-12-31 Adir Cie Nouveaux derives a structure naphtalenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5591768A (en) * 1990-12-04 1997-01-07 State Of Oregan, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Methods for treating circadian rhythm phase disturbances
EP0518468B1 (en) * 1991-05-09 1999-06-30 Neurim Pharmaceuticals (1991) Limited Melatonin containing compositions
FR2680507B1 (fr) 1991-08-23 1993-10-08 Adir Cie Nouvelles naphtylethylurees et naphtylethylthiourees, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
ATE141051T1 (de) * 1992-04-07 1996-08-15 Neurim Pharma 1991 Verwendung von melatonin zur herstellung eines arzneimittels zur behandlung der gutartigen prostatahyperplasie
US5449683A (en) * 1992-10-01 1995-09-12 Massachussetts Institute Of Technology Methods of inducing sleep using melatonin
IL103411A (en) 1992-10-11 1996-11-14 Neurim Pharma 1991 Melatonin Controlled Pharmacy Preparation for the Correction of Melatonin Deficiency or Distortion in Melatonin in Human Plasma
TW336932B (en) 1992-12-17 1998-07-21 Pfizer Amino-substituted pyrazoles
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TW444018B (en) 1992-12-17 2001-07-01 Pfizer Pyrazolopyrimidines
ES2128544T3 (es) 1992-12-17 1999-05-16 Pfizer Pirrolopirimidinas como antagonistas del crf.
US5712303A (en) 1992-12-17 1998-01-27 Pfizer Inc. Pyrazoles and pyrazolopyrimidines having CRF antagonistic activity
AU7550994A (en) 1993-07-26 1995-02-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Sustained release oral compositions containing melatonin
US5654325A (en) * 1993-11-18 1997-08-05 Eli Lilly And Company Melatonin derivatives for use in treating sleep disorders
US5403851A (en) 1994-04-05 1995-04-04 Interneuron Pharmaceuticals, Inc. Substituted tryptamines, phenalkylamines and related compounds
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
EP0748627A3 (en) 1995-06-14 1997-05-21 Lilly Co Eli Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate
US6274604B1 (en) * 1996-07-17 2001-08-14 Merck & Co., Inc. Alteration of circadian rhythmicity with a tachykinin antagonist
US5776969A (en) 1997-02-27 1998-07-07 Eli Lilly And Company Treatment of sleep disorders
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HK1052655A1 (zh) * 2000-01-05 2003-09-26 纽里姆药品(1991)有限公司 用於治療對抗高血壓藥的抗藥性和相關病症的方法和製劑
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
US6703412B1 (en) * 2002-09-27 2004-03-09 Holly A. Rosenthal Method of treating sleeplessness with melatonin on an acute basis
JP2014533981A (ja) 2011-09-27 2014-12-18 アイビス・メディカル・インコーポレーテッド 胃内インプラントデバイス

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5707652A (en) * 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
EP0513702A2 (en) * 1991-05-13 1992-11-19 I.F.L.O. ISTITUTO FARMACOLOGICO LOMBARDO S.A.S. di Giorgio & Aldo Laguzzi & C. Melatonin derivaties for use in the therapy of sleep disorders and in pre-anaesthetic medication
EP0724878A2 (en) * 1995-02-01 1996-08-07 Neurim Pharmaceuticals (1991) Limited Use of melatonin for treating patients suffering from drug dependencies
NO981489L (no) * 1995-10-03 1998-05-22 Interneuron Pharma Blandinger av melatonin og analgetika samt anvendelser derav

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FAINSTEIN ET AL: "Effects of melatonin in elderly patients with sleep disturbance: a pilot study", CURRENT THERAPEUTIC RESEARCH, vol. 58, no. 12, December 1997 (1997-12-01), pages 990-1000, Dated: 01.01.0001 *

Also Published As

Publication number Publication date
IL144900A0 (en) 2002-06-30
US20040248966A1 (en) 2004-12-09
WO2003015690B1 (en) 2004-03-11
UY27401A1 (es) 2003-02-28
GT200200164A (es) 2003-09-26
US8962024B2 (en) 2015-02-24
EP3103443A1 (en) 2016-12-14
WO2003015690A3 (en) 2003-09-25
CY1118924T1 (el) 2018-01-10
MXPA04001372A (es) 2005-06-06
HK1066161A1 (zh) 2005-03-18
CL2002001701A1 (es) 2010-06-25
HU230786B1 (en) 2018-05-02
IS7136A (is) 2004-01-30
NZ531318A (en) 2005-08-26
PY0218122A (es) 2004-03-01
IS3004B (is) 2018-09-15
JP2005501095A (ja) 2005-01-13
EP1441702B1 (en) 2017-05-10
DK1441702T3 (en) 2017-06-06
EP1441702A4 (en) 2007-09-26
JO3446B1 (ar) 2020-07-05
EP3103443B1 (en) 2021-06-30
PA8552301A1 (es) 2003-06-30
NO20040087L (no) 2004-02-19
PT1441702T (pt) 2017-06-02
CN100453078C (zh) 2009-01-21
CA2454699C (en) 2012-03-27
DK3103443T3 (da) 2021-08-30
CA2454699A1 (en) 2003-02-27
AU2002326114C1 (en) 2019-03-21
CR7271A (es) 2004-05-17
ES2882584T3 (es) 2021-12-02
LT1441702T (lt) 2017-06-12
ZA200402005B (en) 2005-07-27
KR20040032917A (ko) 2004-04-17
NO334788B1 (no) 2014-05-26
EP1441702A2 (en) 2004-08-04
HUP0401042A2 (hu) 2004-08-30
AU2002326114B2 (en) 2007-03-08
RU2560840C2 (ru) 2015-08-20
SI1441702T1 (sl) 2017-08-31
PE20030331A1 (es) 2003-06-27
HUP0401042A3 (en) 2009-07-28
BR0211855A (pt) 2004-09-21
ES2626591T3 (es) 2017-07-25
IL144900A (en) 2013-12-31
RU2011131532A (ru) 2013-03-27
AR034975A1 (es) 2004-03-24
WO2003015690A2 (en) 2003-02-27
UA87262C2 (uk) 2009-07-10
CY1124763T1 (el) 2022-07-22
AU2002326114A1 (en) 2003-03-03
CN1541092A (zh) 2004-10-27
PL367872A1 (en) 2005-03-07
PT3103443T (pt) 2021-08-12
EA200400302A1 (ru) 2004-10-28

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