HU230786B1 - Pharmaceutical compositions suitable for treating primary insomnia - Google Patents

Pharmaceutical compositions suitable for treating primary insomnia Download PDF

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Publication number
HU230786B1
HU230786B1 HU0401042A HUP0401042A HU230786B1 HU 230786 B1 HU230786 B1 HU 230786B1 HU 0401042 A HU0401042 A HU 0401042A HU P0401042 A HUP0401042 A HU P0401042A HU 230786 B1 HU230786 B1 HU 230786B1
Authority
HU
Hungary
Prior art keywords
sleep
melatonin
patients
medicament
primary insomnia
Prior art date
Application number
HU0401042A
Other languages
English (en)
Hungarian (hu)
Inventor
Nava Zisapel
Original Assignee
Neurim Pharmaceuticals 1991 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11075696&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HU230786(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharmaceuticals 1991 Ltd filed Critical Neurim Pharmaceuticals 1991 Ltd
Publication of HUP0401042A2 publication Critical patent/HUP0401042A2/hu
Publication of HUP0401042A3 publication Critical patent/HUP0401042A3/hu
Publication of HU230786B1 publication Critical patent/HU230786B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Inorganic Chemistry (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
HU0401042A 2001-08-14 2002-08-12 Pharmaceutical compositions suitable for treating primary insomnia HU230786B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL144900A IL144900A (en) 2001-08-14 2001-08-14 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
PCT/IL2002/000662 WO2003015690A2 (en) 2001-08-14 2002-08-12 Method for treating primary insomnia

Publications (3)

Publication Number Publication Date
HUP0401042A2 HUP0401042A2 (hu) 2004-08-30
HUP0401042A3 HUP0401042A3 (en) 2009-07-28
HU230786B1 true HU230786B1 (en) 2018-05-02

Family

ID=11075696

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401042A HU230786B1 (en) 2001-08-14 2002-08-12 Pharmaceutical compositions suitable for treating primary insomnia

Country Status (35)

Country Link
US (1) US8962024B2 (OSRAM)
EP (2) EP3103443B1 (OSRAM)
JP (1) JP2005501095A (OSRAM)
KR (1) KR20040032917A (OSRAM)
CN (1) CN100453078C (OSRAM)
AR (1) AR034975A1 (OSRAM)
AU (1) AU2002326114C1 (OSRAM)
BR (1) BR0211855A (OSRAM)
CA (1) CA2454699C (OSRAM)
CL (1) CL2002001701A1 (OSRAM)
CR (1) CR7271A (OSRAM)
CY (2) CY1118924T1 (OSRAM)
DK (2) DK1441702T3 (OSRAM)
EA (1) EA200400302A1 (OSRAM)
ES (2) ES2626591T3 (OSRAM)
GT (1) GT200200164A (OSRAM)
HU (1) HU230786B1 (OSRAM)
IL (1) IL144900A (OSRAM)
IS (1) IS3004B (OSRAM)
JO (1) JO3446B1 (OSRAM)
LT (1) LT1441702T (OSRAM)
MX (1) MXPA04001372A (OSRAM)
NO (1) NO334788B2 (OSRAM)
NZ (1) NZ531318A (OSRAM)
PA (1) PA8552301A1 (OSRAM)
PE (1) PE20030331A1 (OSRAM)
PL (1) PL367872A1 (OSRAM)
PT (2) PT3103443T (OSRAM)
PY (1) PY0218122A (OSRAM)
RU (1) RU2560840C2 (OSRAM)
SI (1) SI1441702T1 (OSRAM)
UA (1) UA87262C2 (OSRAM)
UY (1) UY27401A1 (OSRAM)
WO (1) WO2003015690A2 (OSRAM)
ZA (1) ZA200402005B (OSRAM)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
IL149377A (en) * 2002-04-28 2012-10-31 Neurim Pharma 1991 Pharmaceutical formulation comprising melatonin for the potentiation of the effect of hypnotic compounds
AR056076A1 (es) * 2005-09-20 2007-09-19 Takeda Pharmaceutical Agente profilactico o terapeutico para el desorden de sueno
US20070088079A1 (en) * 2005-09-20 2007-04-19 Takeda Pharmaceutical Company Limited Prophylactic or therapeutic agent for sleep disorder
WO2007134077A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
US8940326B2 (en) 2007-03-19 2015-01-27 Vita Sciences Llc Transdermal patch and method for delivery of vitamin B12
WO2008122102A1 (en) * 2007-04-05 2008-10-16 Iomedix Development International Srl Melatonin-based composition for improved sleep
US20080248106A1 (en) 2007-04-05 2008-10-09 Marvin Heuer Melatonin-based composition for improved sleep
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
WO2012103411A2 (en) * 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
MX386987B (es) 2016-10-31 2025-03-19 Neurim Pharma 1991 Mini-tabletas de melatonina y métodos de fabricación de las mismas.
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same

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DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
US5151446A (en) 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
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US5707652A (en) 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
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EP0518468B1 (en) * 1991-05-09 1999-06-30 Neurim Pharmaceuticals (1991) Limited Melatonin containing compositions
IT1251544B (it) * 1991-05-13 1995-05-17 Gabriele Biella Composizioni farmaceutiche attive nella terapia dei disturbi del sonno comprendenti melatonina o un suo derivato in associazione con un derivato benzodiazepinico
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IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
US6703412B1 (en) * 2002-09-27 2004-03-09 Holly A. Rosenthal Method of treating sleeplessness with melatonin on an acute basis
JP2014533981A (ja) 2011-09-27 2014-12-18 アイビス・メディカル・インコーポレーテッド 胃内インプラントデバイス

Also Published As

Publication number Publication date
IL144900A0 (en) 2002-06-30
US20040248966A1 (en) 2004-12-09
WO2003015690B1 (en) 2004-03-11
UY27401A1 (es) 2003-02-28
GT200200164A (es) 2003-09-26
US8962024B2 (en) 2015-02-24
EP3103443A1 (en) 2016-12-14
WO2003015690A3 (en) 2003-09-25
CY1118924T1 (el) 2018-01-10
MXPA04001372A (es) 2005-06-06
HK1066161A1 (zh) 2005-03-18
CL2002001701A1 (es) 2010-06-25
IS7136A (is) 2004-01-30
NZ531318A (en) 2005-08-26
PY0218122A (es) 2004-03-01
IS3004B (is) 2018-09-15
JP2005501095A (ja) 2005-01-13
EP1441702B1 (en) 2017-05-10
DK1441702T3 (en) 2017-06-06
EP1441702A4 (en) 2007-09-26
JO3446B1 (ar) 2020-07-05
EP3103443B1 (en) 2021-06-30
PA8552301A1 (es) 2003-06-30
NO20040087L (no) 2004-02-19
PT1441702T (pt) 2017-06-02
CN100453078C (zh) 2009-01-21
CA2454699C (en) 2012-03-27
DK3103443T3 (da) 2021-08-30
CA2454699A1 (en) 2003-02-27
AU2002326114C1 (en) 2019-03-21
CR7271A (es) 2004-05-17
ES2882584T3 (es) 2021-12-02
LT1441702T (lt) 2017-06-12
ZA200402005B (en) 2005-07-27
KR20040032917A (ko) 2004-04-17
NO334788B1 (no) 2014-05-26
EP1441702A2 (en) 2004-08-04
HUP0401042A2 (hu) 2004-08-30
AU2002326114B2 (en) 2007-03-08
RU2560840C2 (ru) 2015-08-20
SI1441702T1 (sl) 2017-08-31
PE20030331A1 (es) 2003-06-27
HUP0401042A3 (en) 2009-07-28
BR0211855A (pt) 2004-09-21
ES2626591T3 (es) 2017-07-25
IL144900A (en) 2013-12-31
RU2011131532A (ru) 2013-03-27
AR034975A1 (es) 2004-03-24
WO2003015690A2 (en) 2003-02-27
UA87262C2 (uk) 2009-07-10
CY1124763T1 (el) 2022-07-22
NO334788B2 (no) 2014-05-26
AU2002326114A1 (en) 2003-03-03
CN1541092A (zh) 2004-10-27
PL367872A1 (en) 2005-03-07
PT3103443T (pt) 2021-08-12
EA200400302A1 (ru) 2004-10-28

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