NO329773B1 - In vitro fremgangsmate for transfeksjon av et polynukleotid inn i celler, et transfeksjonsmiddel og en farmasoytisk sammensetning. - Google Patents
In vitro fremgangsmate for transfeksjon av et polynukleotid inn i celler, et transfeksjonsmiddel og en farmasoytisk sammensetning. Download PDFInfo
- Publication number
- NO329773B1 NO329773B1 NO20020983A NO20020983A NO329773B1 NO 329773 B1 NO329773 B1 NO 329773B1 NO 20020983 A NO20020983 A NO 20020983A NO 20020983 A NO20020983 A NO 20020983A NO 329773 B1 NO329773 B1 NO 329773B1
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- NO
- Norway
- Prior art keywords
- cyclodextrin
- beta
- cells
- polynucleotide
- transfection
- Prior art date
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
- Y10T436/105831—Protein or peptide standard or control [e.g., hemoglobin, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Urology & Nephrology (AREA)
- Dermatology (AREA)
- Reproductive Health (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Gynecology & Obstetrics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ2593A AUPQ259399A0 (en) | 1999-09-01 | 1999-09-01 | Therapeutic agents |
| PCT/SG2000/000130 WO2001015755A2 (en) | 1999-09-01 | 2000-09-01 | Methods and compositions for delivery of pharmaceutical agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20020983D0 NO20020983D0 (no) | 2002-02-27 |
| NO20020983L NO20020983L (no) | 2002-04-24 |
| NO329773B1 true NO329773B1 (no) | 2010-12-13 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20020983A NO329773B1 (no) | 1999-09-01 | 2002-02-27 | In vitro fremgangsmate for transfeksjon av et polynukleotid inn i celler, et transfeksjonsmiddel og en farmasoytisk sammensetning. |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US7320963B2 (ja) |
| EP (1) | EP1208218B1 (ja) |
| JP (1) | JP4995388B2 (ja) |
| AT (1) | ATE292187T1 (ja) |
| AU (2) | AUPQ259399A0 (ja) |
| CA (1) | CA2384425C (ja) |
| DE (1) | DE60019134T2 (ja) |
| ES (1) | ES2240157T3 (ja) |
| NO (1) | NO329773B1 (ja) |
| TW (1) | TWI262085B (ja) |
| WO (1) | WO2001015755A2 (ja) |
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| AUPQ259399A0 (en) * | 1999-09-01 | 1999-09-23 | Lustre Investments Pte Ltd | Therapeutic agents |
| EP1233671A4 (en) * | 1999-11-29 | 2005-11-02 | Mirus Corp | COMPOSITIONS AND METHODS OF DISPOSING MEDICAMENTS USING AMPHIPHILIC BINDING MOLECULARS |
| WO2003038103A1 (en) * | 2001-10-29 | 2003-05-08 | Atso Raasmaja | Method for gene transfection using synergistic combinations of cationic lipids and cationic polymers |
| US7153905B2 (en) * | 2003-03-21 | 2006-12-26 | The General Hospital Corporation | Hyperbranched dendron and methods of synthesis and use thereof |
| US8545830B2 (en) * | 2003-03-24 | 2013-10-01 | University Of Tennessee Research Foundation | Multi-functional polymeric materials and their uses |
| JP4649571B2 (ja) * | 2003-07-16 | 2011-03-09 | 英俊 有馬 | 細胞にｒｎａを導入する方法 |
| CA2577447C (en) | 2004-08-16 | 2017-08-01 | Cellresearch Corporation Pte Ltd | Isolation of stem/progenitor cells from amniotic membrane of umbilical cord |
| US9346029B2 (en) | 2005-06-06 | 2016-05-24 | The University Of British Columbia | Polymer-based serum albumin substitute |
| EP1937326B1 (en) | 2005-10-21 | 2018-09-12 | CellResearch Corporation Pte Ltd | Isolation and cultivation of stem/progenitor cells from the amniotic membrane of umbilical cord and uses of cells differentiated therefrom |
| ITMI20071173A1 (it) * | 2007-06-11 | 2008-12-12 | Univ Degli Studi Milano | Polimeri iperramificati a base di ciclodestrine e poli(amidoammine) per il rilascio controllato di farmaci insolubili |
| CN106432747B (zh) | 2010-03-01 | 2019-11-05 | 不列颠哥伦比亚大学 | 衍生的超支化聚丙三醇 |
| CA2819635A1 (en) | 2010-12-01 | 2012-06-07 | Spinal Modulation, Inc. | Directed delivery of agents to neural anatomy |
| US8962662B2 (en) | 2011-11-15 | 2015-02-24 | Byocoat Enterprises, Inc. | Antimicrobial compositions and methods of use thereof |
| WO2014025795A1 (en) | 2012-08-07 | 2014-02-13 | Northeastern University | Compositions for the delivery of rna and drugs into cells |
| WO2014204264A1 (ko) * | 2013-06-21 | 2014-12-24 | 가톨릭대학교 산학협력단 | 약물 전달용 환원성 또는 비환원성 폴리뉴클레오타이드 고분자 및 이의 제조방법 |
| CA2944181C (en) | 2014-03-27 | 2019-09-17 | Salk Institute For Biological Studies | Compositions and methods for treating type 1 and type 2 diabetes and related disorders |
| US10920199B2 (en) | 2015-02-27 | 2021-02-16 | Salk Institute For Biological Studies | Reprogramming progenitor compositions and methods of use therefore |
| AU2017269364B2 (en) | 2016-05-25 | 2023-08-31 | Salk Institute For Biological Studies | Compositions and methods for organoid generation and disease modeling |
| CN106924746B (zh) * | 2017-03-03 | 2020-11-03 | 中山大学 | 复合基因载体及其应用 |
| WO2019115472A1 (en) | 2017-12-11 | 2019-06-20 | Fondazione Istituto Firc Di Oncologia Molecolare (Ifom) | Polycomb inhibitors and uses thereof |
| US20220107320A1 (en) | 2019-02-15 | 2022-04-07 | Incelldx, Inc. | Assaying Bladder-Associated Samples, Identifying and Treating Bladder-Associated Neoplasia, and Kits for Use Therein |
| CN113181119B (zh) * | 2021-05-08 | 2023-08-29 | 深圳市第二人民医院(深圳市转化医学研究院) | 载药系统及其制备方法、药物组合物 |
| CN113082001B (zh) * | 2021-05-25 | 2023-05-26 | 中国科学院广州生物医药与健康研究院 | 一种核酸递送系统及其制备方法和应用 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5703055A (en) * | 1989-03-21 | 1997-12-30 | Wisconsin Alumni Research Foundation | Generation of antibodies through lipid mediated DNA delivery |
| US5264618A (en) | 1990-04-19 | 1993-11-23 | Vical, Inc. | Cationic lipids for intracellular delivery of biologically active molecules |
| ES2188612T3 (es) | 1993-04-22 | 2003-07-01 | Skyepharma Inc | Liposomas multivesiculares de ciclodextrina para encapsular compuestos farmacologicos y metodos para su uso. |
| US5614503A (en) | 1993-11-12 | 1997-03-25 | Aronex Pharmaceuticals, Inc. | Amphipathic nucleic acid transporter |
| US5691316A (en) | 1994-06-01 | 1997-11-25 | Hybridon, Inc. | Cyclodextrin cellular delivery system for oligonucleotides |
| US5543152A (en) | 1994-06-20 | 1996-08-06 | Inex Pharmaceuticals Corporation | Sphingosomes for enhanced drug delivery |
| US5993850A (en) | 1994-09-13 | 1999-11-30 | Skyepharma Inc. | Preparation of multivesicular liposomes for controlled release of encapsulated biologically active substances |
| JPH11508231A (ja) | 1995-05-26 | 1999-07-21 | ソマティックス セラピー コーポレイション | 安定な脂質／核酸複合体を含む送達ビヒクル |
| US5830878A (en) | 1995-06-07 | 1998-11-03 | Megabios Corporation | Cationic lipid: DNA complexes for gene targeting |
| US5932241A (en) | 1995-06-07 | 1999-08-03 | Valentis, Incorporated | Cationic lipid DNA complexes for gene targeting |
| ATE209902T1 (de) | 1996-08-19 | 2001-12-15 | Us Gov Health & Human Serv | Neue liposomkomplexe mit erhöhter systemischer verabreichung |
| AU1987197A (en) * | 1997-03-10 | 1998-09-29 | Heather Lynn Davis | Gene delivery to mucosal epithelium for immunization or therapeutic purpose |
| AU6949098A (en) | 1997-04-04 | 1998-10-30 | Valentis, Inc. | Improved methods of delivery using cationic lipids and helper lipids |
| WO1998051285A2 (en) * | 1997-05-15 | 1998-11-19 | Genzyme Corporation | Cationic amphiphile formulations |
| JP2001500897A (ja) * | 1997-06-10 | 2001-01-23 | ジエンザイム コーポレイション | 治療用分子の細胞内送達のための陽イオン性両親媒性組成物 |
| US6391336B1 (en) | 1997-09-22 | 2002-05-21 | Royer Biomedical, Inc. | Inorganic-polymer complexes for the controlled release of compounds including medicinals |
| AU9404398A (en) | 1997-09-23 | 1999-04-12 | Megabios Corporation | Methods for preparing lipids/polynucleotide transfection complexes |
| AUPQ259399A0 (en) * | 1999-09-01 | 1999-09-23 | Lustre Investments Pte Ltd | Therapeutic agents |
| EP1242609A2 (en) * | 1999-12-30 | 2002-09-25 | Novartis AG | Novel colloid synthetic vectors for gene therapy |
-
1999
- 1999-09-01 AU AUPQ2593A patent/AUPQ259399A0/en not_active Abandoned
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2000
- 2000-09-01 AU AU73275/00A patent/AU781684B2/en not_active Ceased
- 2000-09-01 EP EP00961303A patent/EP1208218B1/en not_active Expired - Lifetime
- 2000-09-01 ES ES00961303T patent/ES2240157T3/es not_active Expired - Lifetime
- 2000-09-01 AT AT00961303T patent/ATE292187T1/de active
- 2000-09-01 WO PCT/SG2000/000130 patent/WO2001015755A2/en active IP Right Grant
- 2000-09-01 CA CA2384425A patent/CA2384425C/en not_active Expired - Fee Related
- 2000-09-01 DE DE60019134T patent/DE60019134T2/de not_active Expired - Lifetime
- 2000-09-01 JP JP2001520166A patent/JP4995388B2/ja not_active Expired - Fee Related
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2001
- 2001-02-12 TW TW090103013A patent/TWI262085B/zh not_active IP Right Cessation
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2002
- 2002-02-27 NO NO20020983A patent/NO329773B1/no not_active IP Right Cessation
- 2002-03-01 US US10/086,973 patent/US7320963B2/en not_active Expired - Fee Related
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2007
- 2007-11-26 US US11/986,829 patent/US7709457B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20090054364A1 (en) | 2009-02-26 |
| JP2003508456A (ja) | 2003-03-04 |
| ATE292187T1 (de) | 2005-04-15 |
| US7320963B2 (en) | 2008-01-22 |
| CA2384425C (en) | 2011-01-25 |
| DE60019134T2 (de) | 2006-02-09 |
| WO2001015755A3 (en) | 2002-02-28 |
| DE60019134D1 (de) | 2005-05-04 |
| TWI262085B (en) | 2006-09-21 |
| JP4995388B2 (ja) | 2012-08-08 |
| WO2001015755A2 (en) | 2001-03-08 |
| US7709457B2 (en) | 2010-05-04 |
| EP1208218A2 (en) | 2002-05-29 |
| NO20020983D0 (no) | 2002-02-27 |
| AUPQ259399A0 (en) | 1999-09-23 |
| AU781684B2 (en) | 2005-06-09 |
| CA2384425A1 (en) | 2001-03-08 |
| ES2240157T3 (es) | 2005-10-16 |
| EP1208218B1 (en) | 2005-03-30 |
| US20020146830A1 (en) | 2002-10-10 |
| NO20020983L (no) | 2002-04-24 |
| AU7327500A (en) | 2001-03-26 |
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| MM1K | Lapsed by not paying the annual fees |