NO329592B1 - Anvendelse av ikke-merket B-celleutarmende antistoff for fremstilling av et medikament til reduksjon av hematologisk toksisitet fra radiomerket antistoff - Google Patents

Anvendelse av ikke-merket B-celleutarmende antistoff for fremstilling av et medikament til reduksjon av hematologisk toksisitet fra radiomerket antistoff Download PDF

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Publication number
NO329592B1
NO329592B1 NO20020637A NO20020637A NO329592B1 NO 329592 B1 NO329592 B1 NO 329592B1 NO 20020637 A NO20020637 A NO 20020637A NO 20020637 A NO20020637 A NO 20020637A NO 329592 B1 NO329592 B1 NO 329592B1
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NO
Norway
Prior art keywords
antibody
use according
cell
bone marrow
radiolabeled
Prior art date
Application number
NO20020637A
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English (en)
Norwegian (no)
Other versions
NO20020637L (no
NO20020637D0 (no
Inventor
William Rastetter
Christine White
Original Assignee
Biogen Idec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Idec Inc filed Critical Biogen Idec Inc
Publication of NO20020637D0 publication Critical patent/NO20020637D0/no
Publication of NO20020637L publication Critical patent/NO20020637L/no
Publication of NO329592B1 publication Critical patent/NO329592B1/no

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Physiology (AREA)
  • Ecology (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20020637A 1999-08-11 2002-02-08 Anvendelse av ikke-merket B-celleutarmende antistoff for fremstilling av et medikament til reduksjon av hematologisk toksisitet fra radiomerket antistoff NO329592B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14828899P 1999-08-11 1999-08-11
US09/625,856 US6451284B1 (en) 1999-08-11 2000-07-26 Clinical parameters for determining hematologic toxicity prior to radioimmunotheraphy
PCT/US2000/020733 WO2001010461A1 (en) 1999-08-11 2000-07-31 New clinical parameters for determining hematologic toxicity prior to radioimmunotherapy

Publications (3)

Publication Number Publication Date
NO20020637D0 NO20020637D0 (no) 2002-02-08
NO20020637L NO20020637L (no) 2002-04-11
NO329592B1 true NO329592B1 (no) 2010-11-22

Family

ID=26845721

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020637A NO329592B1 (no) 1999-08-11 2002-02-08 Anvendelse av ikke-merket B-celleutarmende antistoff for fremstilling av et medikament til reduksjon av hematologisk toksisitet fra radiomerket antistoff

Country Status (17)

Country Link
US (3) US6451284B1 (https=)
EP (1) EP1207904B1 (https=)
JP (1) JP4662672B2 (https=)
CN (2) CN100540053C (https=)
AT (1) ATE387915T1 (https=)
AU (2) AU780222B2 (https=)
CA (1) CA2378584C (https=)
CY (1) CY1108118T1 (https=)
DE (1) DE60038239T2 (https=)
DK (1) DK1207904T3 (https=)
ES (1) ES2302698T3 (https=)
MX (1) MXPA02001403A (https=)
MY (1) MY135734A (https=)
NO (1) NO329592B1 (https=)
PT (1) PT1207904E (https=)
TW (1) TWI317284B (https=)
WO (1) WO2001010461A1 (https=)

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CA2525251C (en) * 2003-05-09 2015-10-27 Duke University Cd20-specific antibodies and methods employing same
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US7914785B2 (en) 2008-01-02 2011-03-29 Bergen Teknologieverforing As B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome
EP2077281A1 (en) 2008-01-02 2009-07-08 Bergen Teknologioverforing AS Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome
EP2365003A1 (en) 2008-04-11 2011-09-14 Emergent Product Development Seattle, LLC CD37 immunotherapeutic and combination with bifunctional chemotherapeutic thereof
TW201014605A (en) 2008-09-16 2010-04-16 Genentech Inc Methods for treating progressive multiple sclerosis
WO2010075249A2 (en) 2008-12-22 2010-07-01 Genentech, Inc. A method for treating rheumatoid arthritis with b-cell antagonists
CN104059955A (zh) 2009-08-11 2014-09-24 弗·哈夫曼-拉罗切有限公司 在无谷氨酰胺的细胞培养基中的蛋白质生产
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US5843439A (en) * 1992-11-13 1998-12-01 Anderson; Darrell R. Therapeutic application of chimeric and radiolabeled antibodies to human B lymphocyte restricted differentiation antigen for treatment of B cell lymphoma

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Also Published As

Publication number Publication date
AU2005202560B2 (en) 2008-01-31
JP4662672B2 (ja) 2011-03-30
CN1596985A (zh) 2005-03-23
MY135734A (en) 2008-06-30
AU780222B2 (en) 2005-03-10
CA2378584A1 (en) 2001-02-15
CA2378584C (en) 2011-10-11
DE60038239T2 (de) 2009-04-30
MXPA02001403A (es) 2002-08-12
TWI317284B (en) 2009-11-21
NO20020637L (no) 2002-04-11
EP1207904A4 (en) 2002-10-25
DK1207904T3 (da) 2008-07-07
EP1207904A1 (en) 2002-05-29
US7195750B2 (en) 2007-03-27
US6451284B1 (en) 2002-09-17
US20030211038A1 (en) 2003-11-13
PT1207904E (pt) 2008-06-17
ES2302698T3 (es) 2008-08-01
JP2003506414A (ja) 2003-02-18
WO2001010461A1 (en) 2001-02-15
ATE387915T1 (de) 2008-03-15
DE60038239D1 (de) 2008-04-17
NO20020637D0 (no) 2002-02-08
AU2005202560A1 (en) 2005-07-07
CY1108118T1 (el) 2014-02-12
US20070148714A1 (en) 2007-06-28
AU7052100A (en) 2001-03-05
EP1207904B1 (en) 2008-03-05
CN100540053C (zh) 2009-09-16
CN1450911A (zh) 2003-10-22

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