NO329163B1 - Arylerte furan- og tiofenkarboksylsyreamider med kaliumkanalblokkerende virkning, anvendelse av forbindelsene samt farmasoytiske preparater inneholdende disse - Google Patents
Arylerte furan- og tiofenkarboksylsyreamider med kaliumkanalblokkerende virkning, anvendelse av forbindelsene samt farmasoytiske preparater inneholdende disse Download PDFInfo
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- NO329163B1 NO329163B1 NO20032535A NO20032535A NO329163B1 NO 329163 B1 NO329163 B1 NO 329163B1 NO 20032535 A NO20032535 A NO 20032535A NO 20032535 A NO20032535 A NO 20032535A NO 329163 B1 NO329163 B1 NO 329163B1
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- pharmaceutically acceptable
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- HDACQVRGBOVJII-JBDAPHQKSA-N ramipril Chemical compound C([C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@@H](C[C@@H]2CCC[C@@H]21)C(O)=O)CC1=CC=CC=C1 HDACQVRGBOVJII-JBDAPHQKSA-N 0.000 description 1
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- CTIRHWCPXYGDGF-HDICACEKSA-N tedisamil Chemical compound [H][C@]12CN(CC3CC3)C[C@]([H])(CN(CC3CC3)C1)C21CCCC1 CTIRHWCPXYGDGF-HDICACEKSA-N 0.000 description 1
- DFNZFCPEUDSNEO-UHFFFAOYSA-N tert-butyl n-[(2-bromophenyl)methyl]carbamate Chemical compound CC(C)(C)OC(=O)NCC1=CC=CC=C1Br DFNZFCPEUDSNEO-UHFFFAOYSA-N 0.000 description 1
- VTVJORGOSQDHJV-UHFFFAOYSA-N tert-butyl n-[[2-[2-(3-methylbutylcarbamoyl)thiophen-3-yl]phenyl]methyl]carbamate Chemical compound S1C=CC(C=2C(=CC=CC=2)CNC(=O)OC(C)(C)C)=C1C(=O)NCCC(C)C VTVJORGOSQDHJV-UHFFFAOYSA-N 0.000 description 1
- 125000005931 tert-butyloxycarbonyl group Chemical group [H]C([H])([H])C(OC(*)=O)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10061876A DE10061876A1 (de) | 2000-12-12 | 2000-12-12 | Arylierte Furan- und Thiophencarbonsäureamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| PCT/EP2001/013958 WO2002048131A1 (de) | 2000-12-12 | 2001-11-29 | Arylierte furan- und thiophencarbonsäureamide mit kalium kanal blockierender wirkung |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20032535D0 NO20032535D0 (no) | 2003-06-04 |
| NO20032535L NO20032535L (no) | 2003-07-29 |
| NO329163B1 true NO329163B1 (no) | 2010-08-30 |
Family
ID=7666837
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20032535A NO329163B1 (no) | 2000-12-12 | 2003-06-04 | Arylerte furan- og tiofenkarboksylsyreamider med kaliumkanalblokkerende virkning, anvendelse av forbindelsene samt farmasoytiske preparater inneholdende disse |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6982279B2 (zh) |
| EP (1) | EP1349846B1 (zh) |
| JP (1) | JP4252798B2 (zh) |
| KR (1) | KR20030061846A (zh) |
| CN (1) | CN1225463C (zh) |
| AR (1) | AR032781A1 (zh) |
| AT (1) | ATE288906T1 (zh) |
| AU (2) | AU2002235743B2 (zh) |
| BR (1) | BR0116084A (zh) |
| CA (1) | CA2431095A1 (zh) |
| CZ (1) | CZ20031633A3 (zh) |
| DE (2) | DE10061876A1 (zh) |
| DK (1) | DK1349846T3 (zh) |
| EE (1) | EE05306B1 (zh) |
| ES (1) | ES2236335T3 (zh) |
| HK (1) | HK1061850A1 (zh) |
| HR (1) | HRP20030469A2 (zh) |
| HU (1) | HUP0303665A3 (zh) |
| IL (2) | IL156314A0 (zh) |
| MX (1) | MXPA03004770A (zh) |
| NO (1) | NO329163B1 (zh) |
| NZ (1) | NZ526383A (zh) |
| PL (1) | PL362410A1 (zh) |
| PT (1) | PT1349846E (zh) |
| RS (1) | RS50336B (zh) |
| RU (1) | RU2275366C2 (zh) |
| SK (1) | SK287464B6 (zh) |
| TW (1) | TWI288134B (zh) |
| WO (1) | WO2002048131A1 (zh) |
| ZA (1) | ZA200304091B (zh) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8329924B2 (en) * | 2001-06-11 | 2012-12-11 | Vertex Pharmaceuticals (Canada) Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
| JP4544857B2 (ja) * | 2001-06-11 | 2010-09-15 | ヴァイロケム ファーマ インコーポレイテッド | Ｆｌａｖｉｖｉｒｕｓ感染の治療または予防のための化合物および方法 |
| US7402608B2 (en) * | 2002-12-10 | 2008-07-22 | Virochem Pharma Inc. | Compounds and methods for the treatment or prevention of Flavivirus infections |
| GB0315950D0 (en) | 2003-06-11 | 2003-08-13 | Xention Discovery Ltd | Compounds |
| EP1493739A1 (fr) * | 2003-07-03 | 2005-01-05 | Warner-Lambert Company LLC | Dérivés thiophényliques d'aminoacides, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent |
| GB0324269D0 (en) * | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
| GB0412986D0 (en) | 2004-06-10 | 2004-07-14 | Xention Discovery Ltd | Compounds |
| US7569589B2 (en) | 2004-07-29 | 2009-08-04 | Merck & Co., Inc. | Potassium channel inhibitors |
| US7576212B2 (en) | 2004-12-09 | 2009-08-18 | Xention Limited | Thieno[2,3-B] pyridines as potassium channel inhibitors |
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