NO328812B1 - Middel for diagnose av vevsproliferasjonsaktivitet, nukleosidderivat og fremgangsmate for fremstilling av en radiomerket forbindelse - Google Patents
Middel for diagnose av vevsproliferasjonsaktivitet, nukleosidderivat og fremgangsmate for fremstilling av en radiomerket forbindelse Download PDFInfo
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- NO328812B1 NO328812B1 NO20024324A NO20024324A NO328812B1 NO 328812 B1 NO328812 B1 NO 328812B1 NO 20024324 A NO20024324 A NO 20024324A NO 20024324 A NO20024324 A NO 20024324A NO 328812 B1 NO328812 B1 NO 328812B1
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- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Pain & Pain Management (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001014954 | 2001-01-23 | ||
| PCT/JP2002/000408 WO2002058740A1 (fr) | 2001-01-23 | 2002-01-22 | Medicaments destines au diagnostic de l'activite reproductrice tissulaire ou au traitement de maladies proliferatives |
Publications (3)
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| NO20024324D0 NO20024324D0 (no) | 2002-09-10 |
| NO20024324L NO20024324L (no) | 2002-11-07 |
| NO328812B1 true NO328812B1 (no) | 2010-05-18 |
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| Country | Link |
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| US (2) | US7045115B2 (fr) |
| EP (1) | EP1270017B1 (fr) |
| JP (1) | JP4210118B2 (fr) |
| KR (1) | KR100867729B1 (fr) |
| CN (1) | CN100400107C (fr) |
| AT (1) | ATE322912T1 (fr) |
| AU (1) | AU2002226690B2 (fr) |
| CA (1) | CA2402991C (fr) |
| DE (1) | DE60210538T2 (fr) |
| HK (1) | HK1059396A1 (fr) |
| NO (1) | NO328812B1 (fr) |
| NZ (1) | NZ520934A (fr) |
| TW (1) | TWI247609B (fr) |
| WO (1) | WO2002058740A1 (fr) |
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| US7344702B2 (en) | 2004-02-13 | 2008-03-18 | Bristol-Myers Squibb Pharma Company | Contrast agents for myocardial perfusion imaging |
| EP1673353A4 (fr) * | 2003-09-05 | 2007-03-28 | Einstein Coll Med | Structure de l'etat de transition et inhibiteurs des thymidine phosphorylases |
| WO2005027962A1 (fr) * | 2003-09-18 | 2005-03-31 | Isis Pharmaceuticals, Inc. | 4’-thionucleosides et composes d'oligomeres |
| US7485283B2 (en) * | 2004-04-28 | 2009-02-03 | Lantheus Medical Imaging | Contrast agents for myocardial perfusion imaging |
| JP4841231B2 (ja) * | 2005-11-07 | 2011-12-21 | 日本メジフィジックス株式会社 | 組織増殖能診断用薬剤 |
| CA2649182C (fr) | 2006-04-07 | 2018-01-02 | The Board Of Regents Of The University Of Texas System | Procedes et compositions portant sur des particules de phage de virus adenoassocie |
| US7928210B2 (en) | 2007-03-01 | 2011-04-19 | Siemens Medical Solutions Usa, Inc. | Nucleoside based proliferation imaging markers |
| EP2155231B1 (fr) * | 2007-04-10 | 2012-08-08 | The Johns Hopkins University | Imagerie et thérapie des tumeurs associées à un virus |
| CA2967254C (fr) * | 2008-02-29 | 2019-03-26 | Lantheus Medical Imaging, Inc. | Agents de contraste destine aux applications comprenant l'imagerie du cancer |
| GB0815831D0 (en) * | 2008-09-01 | 2008-10-08 | Imp Innovations Ltd | Compounds |
| EP2419096B1 (fr) | 2009-04-15 | 2019-11-13 | Lantheus Medical Imaging, Inc. | Stabilisation de compositions radiopharmaceutiques à l'aide d'acide ascorbique |
| JP6092628B2 (ja) | 2010-02-08 | 2017-03-08 | ランセウス メディカル イメージング， インコーポレイテッド | 造影剤およびその中間体を合成するための方法および装置 |
| US8835612B2 (en) * | 2010-10-09 | 2014-09-16 | Fabio Polato | Isolation of phosphoproteins, glycoproteins and fragments thereof |
| JP5794521B2 (ja) * | 2011-03-29 | 2015-10-14 | 国立大学法人福井大学 | アポトーシス誘導剤 |
| SG11201406080VA (en) | 2012-03-28 | 2014-11-27 | Fujifilm Corp | SALT OF 1-(2-DEOXY-2-FLUORO-4-THIO-β-D-ARABINOFURANOSYL)CYTOSINE |
| AU2013203000B9 (en) | 2012-08-10 | 2017-02-02 | Lantheus Medical Imaging, Inc. | Compositions, methods, and systems for the synthesis and use of imaging agents |
| RU2633355C2 (ru) * | 2012-08-13 | 2017-10-12 | Фуджифилм Корпорэйшн | СИНТЕТИЧЕСКОЕ ПРОМЕЖУТОЧНОЕ СОЕДИНЕНИЕ 1-(2-ДЕЗОКСИ-2-ФТОР-4-ТИО-β-D-АРАБИНОФУРАНОЗИЛ)ЦИТОЗИНА, СИНТЕТИЧЕСКОЕ ПРОМЕЖУТОЧНОЕ СОЕДИНЕНИЕ ТИОНУКЛЕОЗИДА И СПОСОБ ИХ ПОЛУЧЕНИЯ |
| JP2014062054A (ja) * | 2012-09-20 | 2014-04-10 | Gyoseiin Genshino Iinkai Kakuno Kenkyusho | よう素−１２３標記チミン類似物［１２３Ｉ］−ＩａｒａＵのプローブ |
| JP6351107B2 (ja) * | 2014-02-18 | 2018-07-04 | 富士フイルム株式会社 | チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物 |
| TWI678373B (zh) | 2014-10-31 | 2019-12-01 | 日商富士軟片股份有限公司 | 硫代核苷衍生物或其鹽及醫藥組合物 |
| WO2018043530A1 (fr) | 2016-08-31 | 2018-03-08 | 富士フイルム株式会社 | Agent antitumoral, activateur d'effet antitumoral et kit anti-tumoral |
| CA3089728C (fr) | 2018-01-29 | 2023-01-10 | Fujifilm Corporation | Agent antitumoral contre le cancer biliaire et methode de traitement du cancer biliaire |
| CN113683648A (zh) * | 2021-08-26 | 2021-11-23 | 上海皓鸿生物医药科技有限公司 | 一种2’-氟-2’-脱氧尿苷的合成方法及其中间体 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE74701B1 (en) * | 1989-10-04 | 1997-07-30 | Univ Birmingham | Further antiviral pyrimidine nucleosides |
| US5077034A (en) | 1990-03-30 | 1991-12-31 | The President And Fellows Of Harvard College | Treatment of tumors with 5-radioiodo-2'-deoxyuridine |
| US5248771A (en) | 1991-06-26 | 1993-09-28 | Triumf | Process for preparing no-carrier-added radiohalogenated vinyl nucleosides |
| GB9421223D0 (en) | 1994-10-21 | 1994-12-07 | Univ Alberta | Tissue imaging in gene therapy |
| US5574148A (en) | 1995-02-02 | 1996-11-12 | President U Fellows Of Harvard College | Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides |
| US5703056A (en) * | 1995-03-15 | 1997-12-30 | Sloan-Kettering Institute For Cancer Research | Non-invasive imaging of gene transfer |
| US5720935A (en) * | 1995-06-09 | 1998-02-24 | President & Fellows Of Harvard College | Rapid synthesis of radiolabeled pyrimidine nucleosides or nucleotides from stannyl precursors |
| WO1996041646A2 (fr) | 1995-06-13 | 1996-12-27 | Dyer, Alison, Margaret | Compositions pharmaceutiques contenant du lornoxicam et de la cyclodextrine |
| US6331287B1 (en) | 1995-08-23 | 2001-12-18 | University Advanced Bio-Imaging Associates | 2′-deoxy-2′-fluoro-d-arabinofuranosyl pyrimidine nucleoside |
| WO2001005439A1 (fr) * | 1999-07-14 | 2001-01-25 | President And Fellows Of Harvard College | Radiodetection de proliferation cellulaire aberrante et therapie contre cette proliferation |
| KR200188038Y1 (ko) | 2000-01-24 | 2000-07-15 | 이정진 | 전자파 피해가 감소되는 안테나 구조를 가진 휴대폰. |
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2002
- 2002-01-18 TW TW091100830A patent/TWI247609B/zh not_active IP Right Cessation
- 2002-01-22 EP EP02716326A patent/EP1270017B1/fr not_active Expired - Lifetime
- 2002-01-22 AU AU2002226690A patent/AU2002226690B2/en not_active Ceased
- 2002-01-22 DE DE60210538T patent/DE60210538T2/de not_active Expired - Lifetime
- 2002-01-22 CA CA002402991A patent/CA2402991C/fr not_active Expired - Fee Related
- 2002-01-22 KR KR1020027012275A patent/KR100867729B1/ko active IP Right Grant
- 2002-01-22 JP JP2002559074A patent/JP4210118B2/ja not_active Expired - Lifetime
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- 2002-01-22 WO PCT/JP2002/000408 patent/WO2002058740A1/fr active IP Right Grant
- 2002-01-22 AT AT02716326T patent/ATE322912T1/de not_active IP Right Cessation
- 2002-01-22 CN CNB028001540A patent/CN100400107C/zh not_active Expired - Fee Related
- 2002-01-22 US US10/239,355 patent/US7045115B2/en not_active Expired - Lifetime
- 2002-09-10 NO NO20024324A patent/NO328812B1/no not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| TWI247609B (en) | 2006-01-21 |
| US7118731B2 (en) | 2006-10-10 |
| NZ520934A (en) | 2004-12-24 |
| CN100400107C (zh) | 2008-07-09 |
| WO2002058740A1 (fr) | 2002-08-01 |
| DE60210538T2 (de) | 2006-10-05 |
| DE60210538D1 (de) | 2006-05-24 |
| EP1270017B1 (fr) | 2006-04-12 |
| US7045115B2 (en) | 2006-05-16 |
| US20050129611A1 (en) | 2005-06-16 |
| CA2402991A1 (fr) | 2002-08-01 |
| CA2402991C (fr) | 2009-06-23 |
| AU2002226690B2 (en) | 2006-07-13 |
| NO20024324D0 (no) | 2002-09-10 |
| US20030124054A1 (en) | 2003-07-03 |
| CN1455683A (zh) | 2003-11-12 |
| JP4210118B2 (ja) | 2009-01-14 |
| ATE322912T1 (de) | 2006-04-15 |
| HK1059396A1 (en) | 2004-07-02 |
| JPWO2002058740A1 (ja) | 2004-05-27 |
| EP1270017A4 (fr) | 2004-04-28 |
| KR100867729B1 (ko) | 2008-11-10 |
| NO20024324L (no) | 2002-11-07 |
| EP1270017A1 (fr) | 2003-01-02 |
| KR20020084212A (ko) | 2002-11-04 |
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