NO326964B1 - Farmasoytisk aktive uridinestere, anvendelser derav, fremgangsmate for fremstilling derav samt farmasoytisk sammensetning inneholdende slike forbindelser - Google Patents

Info

Publication number

NO326964B1

NO326964B1 NO20034782A NO20034782A NO326964B1 NO 326964 B1 NO326964 B1 NO 326964B1 NO 20034782 A NO20034782 A NO 20034782A NO 20034782 A NO20034782 A NO 20034782A NO 326964 B1 NO326964 B1 NO 326964B1

Authority

NO

Norway

Prior art keywords

carbon atoms

alkyl chain

acid

compound

branched

Prior art date

2001-04-30

Links

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• Global Dossier
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• 150000001875 compounds Chemical class 0.000 title claims description 108
• 238000000034 method Methods 0.000 title claims description 29
• 238000002360 preparation method Methods 0.000 title claims description 16
• 239000008194 pharmaceutical composition Substances 0.000 title claims description 15
• 230000008569 process Effects 0.000 title description 5
• -1 fatty acid esters Chemical class 0.000 claims abstract description 104
• DRTQHJPVMGBUCF-PSQAKQOGSA-N beta-L-uridine Natural products O[C@H]1[C@@H](O)[C@H](CO)O[C@@H]1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-PSQAKQOGSA-N 0.000 claims abstract description 23
• DRTQHJPVMGBUCF-UHFFFAOYSA-N uracil arabinoside Natural products OC1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 DRTQHJPVMGBUCF-UHFFFAOYSA-N 0.000 claims abstract description 23
• 229940045145 uridine Drugs 0.000 claims abstract description 23
• 206010012601 diabetes mellitus Diseases 0.000 claims abstract description 14
• MXHRCPNRJAMMIM-SHYZEUOFSA-N 2'-deoxyuridine Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-SHYZEUOFSA-N 0.000 claims abstract description 6
• MXHRCPNRJAMMIM-UHFFFAOYSA-N desoxyuridine Natural products C1C(O)C(CO)OC1N1C(=O)NC(=O)C=C1 MXHRCPNRJAMMIM-UHFFFAOYSA-N 0.000 claims abstract description 3
• 125000004432 carbon atom Chemical group C* 0.000 claims description 123
• 125000000217 alkyl group Chemical group 0.000 claims description 111
• 239000002253 acid Substances 0.000 claims description 44
• 150000003839 salts Chemical class 0.000 claims description 42
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• FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 10
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• 125000001204 arachidyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 claims description 2
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