NO323646B1 - Nukleinsyremolekyl, nukleinsyreprobe, polypeptid, antistoff, hybridom, kit, anvendelse samt fremgangsmate. - Google Patents
Nukleinsyremolekyl, nukleinsyreprobe, polypeptid, antistoff, hybridom, kit, anvendelse samt fremgangsmate. Download PDFInfo
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- NO323646B1 NO323646B1 NO19982794A NO982794A NO323646B1 NO 323646 B1 NO323646 B1 NO 323646B1 NO 19982794 A NO19982794 A NO 19982794A NO 982794 A NO982794 A NO 982794A NO 323646 B1 NO323646 B1 NO 323646B1
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Analytical Chemistry (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| US880995P | 1995-12-18 | 1995-12-18 | |
| US2394396P | 1996-08-14 | 1996-08-14 | |
| PCT/US1996/018859 WO1997022702A1 (en) | 1995-12-18 | 1996-11-25 | Diagnosis and treatment of aur-1 and/or aur-2 related disorders |
Publications (3)
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| NO982794D0 NO982794D0 (no) | 1998-06-17 |
| NO982794L NO982794L (no) | 1998-08-18 |
| NO323646B1 true NO323646B1 (no) | 2007-06-18 |
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| NO19982794A NO323646B1 (no) | 1995-12-18 | 1998-06-17 | Nukleinsyremolekyl, nukleinsyreprobe, polypeptid, antistoff, hybridom, kit, anvendelse samt fremgangsmate. |
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| EP (2) | EP0868519B1 (es) |
| JP (1) | JP3944241B2 (es) |
| KR (1) | KR100459052B1 (es) |
| AT (1) | ATE315654T1 (es) |
| AU (1) | AU716330B2 (es) |
| CA (1) | CA2239692C (es) |
| DE (1) | DE69635740T2 (es) |
| DK (1) | DK0868519T3 (es) |
| ES (1) | ES2255715T3 (es) |
| IL (1) | IL124728A (es) |
| NO (1) | NO323646B1 (es) |
| NZ (1) | NZ323795A (es) |
| PT (1) | PT868519E (es) |
| WO (1) | WO1997022702A1 (es) |
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| US6716575B2 (en) * | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| EP1004667B1 (en) * | 1997-08-15 | 2006-10-18 | Hiroshima University | Cell cycle-regulating proteins |
| US5962232A (en) * | 1998-01-30 | 1999-10-05 | Incyte Pharmaceuticals, Inc. | Protein kinase molecules |
| CN1391562A (zh) * | 1999-09-21 | 2003-01-15 | 阿斯特拉曾尼卡有限公司 | 用作药物的喹唑啉衍生物 |
| US6352858B1 (en) | 2000-09-11 | 2002-03-05 | Isis Pharmaceuticals, Inc. | Antisense modulation of BTAK expression |
| JP2002236125A (ja) * | 2001-02-06 | 2002-08-23 | Igaku Seibutsugaku Kenkyusho:Kk | タンパク質リン酸化酵素活性の測定方法、測定用キット及び測定に用いる抗体 |
| WO2003012046A2 (en) * | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Stk15 (stk6) gene polymorphism and methods of determining cancer risk |
| CA2480635A1 (en) * | 2002-03-28 | 2003-10-09 | Allen D. Delaney | Cancer associated protein kinases and their uses |
| FR2840905B1 (fr) * | 2002-06-12 | 2006-07-07 | Centre Nat Rech Scient | Anticorps monoclonal anti-aurora-a, son procede d'obtention, et ses utilisations dans le diagnostic et le traitement des cancers |
| US7444273B1 (en) * | 2002-06-21 | 2008-10-28 | Takeda San Diego, Inc. | Crystallization of aurora/LPL1P-related kinase |
| WO2004024063A2 (en) * | 2002-09-11 | 2004-03-25 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
| EP1570080A4 (en) * | 2002-11-15 | 2006-03-01 | Genomic Health Inc | GENE EXPRESSION PROFILING OF EGFR-POSITIVE CANCER DISEASE |
| ES2290529T3 (es) | 2002-12-24 | 2008-02-16 | Astrazeneca Ab | Derivados de fosfonooxiquinazolina y su uso farmaceutico. |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| CA2515096A1 (en) * | 2003-02-06 | 2004-08-26 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
| AU2004213871B9 (en) * | 2003-02-20 | 2009-09-03 | Genomic Health, Inc. | Use of intronic RNA to measure gene expression |
| US20050164218A1 (en) * | 2003-05-30 | 2005-07-28 | David Agus | Gene expression markers for response to EGFR inhibitor drugs |
| EP3470535B1 (en) * | 2003-06-24 | 2020-04-01 | Genomic Health, Inc. | Prediction of likelihood of cancer recurrence |
| US7526387B2 (en) * | 2003-07-10 | 2009-04-28 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| WO2005040396A2 (en) * | 2003-10-16 | 2005-05-06 | Genomic Health, Inc. | qRT-PCR ASSAY SYSTEM FOR GENE EXPRESSION PROFILING |
| JP2007514759A (ja) | 2003-12-19 | 2007-06-07 | タケダ サン ディエゴ インコーポレイテッド | キナーゼ阻害剤 |
| JP4718490B2 (ja) * | 2003-12-23 | 2011-07-06 | ジェノミック ヘルス， インコーポレイテッド | フラグメント化ｒｎａの全般的増幅 |
| DK2163650T3 (en) * | 2004-04-09 | 2015-11-02 | Genomic Health Inc | Genekspressionsmarkører for prediction of response to chemotherapy |
| JP4812763B2 (ja) | 2004-05-18 | 2011-11-09 | ライジェル ファーマシューティカルズ， インコーポレイテッド | シクロアルキル置換ピリミジンジアミン化合物およびそれらの用途 |
| US20050282208A1 (en) * | 2004-06-18 | 2005-12-22 | Cytokinetics, Inc. | Cellular phenotype |
| US7550598B2 (en) | 2004-08-18 | 2009-06-23 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| TW200624431A (en) | 2004-09-24 | 2006-07-16 | Hoffmann La Roche | Phthalazinone derivatives, their manufacture and use as pharmaceutical agents |
| US7713973B2 (en) | 2004-10-15 | 2010-05-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| CA2585561C (en) * | 2004-11-05 | 2018-07-17 | Genomic Health, Inc. | Esr1, pgr, bcl2 and scube2 group score as indicators of breast cancer prognosis and prediction of treatment response |
| HUE051605T2 (hu) * | 2004-11-05 | 2021-03-01 | Nsabp Found Inc | Kemoterápiára adott válasz elõrejelzése génexpressziós markereket alkalmazva |
| GB2420559B (en) * | 2004-11-15 | 2008-08-06 | Rigel Pharmaceuticals Inc | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses |
| WO2006108489A1 (en) | 2005-04-14 | 2006-10-19 | F. Hoffmann-La Roche Ag | Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents |
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| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
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| US4945050A (en) * | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5283173A (en) * | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| ATE221915T1 (de) * | 1991-02-22 | 2002-08-15 | American Cyanamid Co | Identifizierung eines menschlichen rezeptor- tyrosinkinasegens |
| EP0703984A1 (en) * | 1993-04-07 | 1996-04-03 | Cancer Research Campaign Technology Limited | Methods for screening of substances for therapeutic activity and yeast for use therein |
| US5830648A (en) * | 1995-05-05 | 1998-11-03 | Sugen, Inc. | Assay and method for transcript imaging |
-
1996
- 1996-11-25 JP JP52280797A patent/JP3944241B2/ja not_active Expired - Lifetime
- 1996-11-25 AU AU10826/97A patent/AU716330B2/en not_active Expired
- 1996-11-25 DK DK96940870T patent/DK0868519T3/da active
- 1996-11-25 IL IL124728A patent/IL124728A/en not_active IP Right Cessation
- 1996-11-25 PT PT96940870T patent/PT868519E/pt unknown
- 1996-11-25 EP EP96940870A patent/EP0868519B1/en not_active Revoked
- 1996-11-25 WO PCT/US1996/018859 patent/WO1997022702A1/en active IP Right Grant
- 1996-11-25 NZ NZ323795A patent/NZ323795A/xx unknown
- 1996-11-25 EP EP05023434A patent/EP1655369A1/en not_active Withdrawn
- 1996-11-25 AT AT96940870T patent/ATE315654T1/de active
- 1996-11-25 ES ES96940870T patent/ES2255715T3/es not_active Expired - Lifetime
- 1996-11-25 DE DE69635740T patent/DE69635740T2/de not_active Revoked
- 1996-11-25 KR KR10-1998-0704572A patent/KR100459052B1/ko not_active IP Right Cessation
- 1996-11-25 US US08/755,728 patent/US5962312A/en not_active Expired - Lifetime
- 1996-11-25 CA CA002239692A patent/CA2239692C/en not_active Expired - Lifetime
-
1997
- 1997-11-19 US US08/974,655 patent/US5972676A/en not_active Expired - Lifetime
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1998
- 1998-06-17 NO NO19982794A patent/NO323646B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JP3944241B2 (ja) | 2007-07-11 |
| NZ323795A (en) | 2000-01-28 |
| PT868519E (pt) | 2006-05-31 |
| CA2239692A1 (en) | 1997-06-26 |
| KR100459052B1 (ko) | 2005-01-15 |
| IL124728A0 (en) | 1999-01-26 |
| ATE315654T1 (de) | 2006-02-15 |
| DE69635740T2 (de) | 2006-09-14 |
| DE69635740D1 (de) | 2006-04-06 |
| IL124728A (en) | 2007-06-03 |
| EP0868519A1 (en) | 1998-10-07 |
| WO1997022702A1 (en) | 1997-06-26 |
| US5962312A (en) | 1999-10-05 |
| AU716330B2 (en) | 2000-02-24 |
| US5972676A (en) | 1999-10-26 |
| NO982794D0 (no) | 1998-06-17 |
| EP1655369A1 (en) | 2006-05-10 |
| JP2000502895A (ja) | 2000-03-14 |
| DK0868519T3 (da) | 2006-05-08 |
| KR20000064437A (ko) | 2000-11-06 |
| CA2239692C (en) | 2008-12-16 |
| AU1082697A (en) | 1997-07-14 |
| ES2255715T3 (es) | 2006-07-01 |
| NO982794L (no) | 1998-08-18 |
| EP0868519B1 (en) | 2006-01-11 |
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| MK1K | Patent expired |