HUE051605T2 - Kemoterápiára adott válasz elõrejelzése génexpressziós markereket alkalmazva - Google Patents
Kemoterápiára adott válasz elõrejelzése génexpressziós markereket alkalmazvaInfo
- Publication number
- HUE051605T2 HUE051605T2 HUE05817266A HUE05817266A HUE051605T2 HU E051605 T2 HUE051605 T2 HU E051605T2 HU E05817266 A HUE05817266 A HU E05817266A HU E05817266 A HUE05817266 A HU E05817266A HU E051605 T2 HUE051605 T2 HU E051605T2
- Authority
- HU
- Hungary
- Prior art keywords
- chemotherapy
- gene expression
- predicting response
- expression markers
- markers
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US62548504P | 2004-11-05 | 2004-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE051605T2 true HUE051605T2 (hu) | 2021-03-01 |
Family
ID=35871164
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE05817266A HUE051605T2 (hu) | 2004-11-05 | 2005-11-04 | Kemoterápiára adott válasz elõrejelzése génexpressziós markereket alkalmazva |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US7930104B2 (hu) |
| EP (1) | EP1836629B1 (hu) |
| JP (1) | JP5020088B2 (hu) |
| AU (1) | AU2005304824B2 (hu) |
| CA (2) | CA3061785A1 (hu) |
| DK (1) | DK1836629T3 (hu) |
| ES (1) | ES2778851T3 (hu) |
| HU (1) | HUE051605T2 (hu) |
| IL (1) | IL182929A (hu) |
| PL (1) | PL1836629T3 (hu) |
| WO (1) | WO2006052862A1 (hu) |
Families Citing this family (90)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3115470B1 (en) * | 2002-03-13 | 2018-07-18 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| EP3470535B1 (en) | 2003-06-24 | 2020-04-01 | Genomic Health, Inc. | Prediction of likelihood of cancer recurrence |
| ES2550614T3 (es) * | 2004-04-09 | 2015-11-11 | Genomic Health, Inc. | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
| CA3061785A1 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| US9867530B2 (en) | 2006-08-14 | 2018-01-16 | Volcano Corporation | Telescopic side port catheter device with imaging system and method for accessing side branch occlusions |
| DK2081950T3 (da) * | 2006-09-21 | 2013-06-03 | Nuclea Biomarkers Llc | Med irinotecanbehandling forbundne ekspressionsprofiler |
| WO2008098086A2 (en) * | 2007-02-06 | 2008-08-14 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | A gene expression profile that predicts ovarian cancer subject response to chemotherapy |
| CA2680591A1 (en) * | 2007-03-15 | 2008-09-25 | Genomic Health, Inc. | Gene expression markers for prediction of patient response to chemotherapy |
| WO2008115561A2 (en) * | 2007-03-21 | 2008-09-25 | Bristol-Myers Squibb Company | Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents |
| WO2009009802A1 (en) | 2007-07-12 | 2009-01-15 | Volcano Corporation | Oct-ivus catheter for concurrent luminal imaging |
| JP5524835B2 (ja) | 2007-07-12 | 2014-06-18 | ヴォルカノ コーポレイション | 生体内撮像用カテーテル |
| US9596993B2 (en) | 2007-07-12 | 2017-03-21 | Volcano Corporation | Automatic calibration systems and methods of use |
| CA2694703A1 (en) * | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| EP2641978A1 (en) * | 2008-05-12 | 2013-09-25 | Genomic Health, Inc. | Tests to predict responsiveness of cancer patients to chemotherapy treatment options |
| TW201000119A (en) * | 2008-06-10 | 2010-01-01 | Oncotherapy Science Inc | MYBL2 epitope peptides and vaccines containing the same |
| US10359425B2 (en) * | 2008-09-09 | 2019-07-23 | Somalogic, Inc. | Lung cancer biomarkers and uses thereof |
| US20100221752A2 (en) * | 2008-10-06 | 2010-09-02 | Somalogic, Inc. | Ovarian Cancer Biomarkers and Uses Thereof |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| US7736861B1 (en) * | 2009-10-19 | 2010-06-15 | Aveo Pharmaceuticals, Inc. | Tivozanib response prediction |
| US9090945B2 (en) | 2009-12-14 | 2015-07-28 | North Carolina State University | Mean DNA copy number of chromosomal regions is of prognostic significance in cancer |
| WO2012006447A2 (en) | 2010-07-07 | 2012-01-12 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US20130116150A1 (en) | 2010-07-09 | 2013-05-09 | Somalogic, Inc. | Lung Cancer Biomarkers and Uses Thereof |
| ES2611000T3 (es) | 2010-07-27 | 2017-05-04 | Genomic Health, Inc. | Método para usar la expresión génica para determinar el pronóstico de cáncer de próstata |
| SG2014007454A (en) | 2010-08-13 | 2014-07-30 | Somalogic Inc | Pancreatic cancer biomarkers and uses thereof |
| US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| US11141063B2 (en) | 2010-12-23 | 2021-10-12 | Philips Image Guided Therapy Corporation | Integrated system architectures and methods of use |
| US11040140B2 (en) | 2010-12-31 | 2021-06-22 | Philips Image Guided Therapy Corporation | Deep vein thrombosis therapeutic methods |
| WO2013033489A1 (en) | 2011-08-31 | 2013-03-07 | Volcano Corporation | Optical rotary joint and methods of use |
| WO2013078537A1 (en) * | 2011-11-28 | 2013-06-06 | National Research Council Of Canada | Paclitaxel response markers for cancer |
| WO2013109690A1 (en) * | 2012-01-17 | 2013-07-25 | Myriad Genetics, Inc. | Breast cancer prognosis signatures |
| US10070827B2 (en) | 2012-10-05 | 2018-09-11 | Volcano Corporation | Automatic image playback |
| US11272845B2 (en) | 2012-10-05 | 2022-03-15 | Philips Image Guided Therapy Corporation | System and method for instant and automatic border detection |
| US9292918B2 (en) | 2012-10-05 | 2016-03-22 | Volcano Corporation | Methods and systems for transforming luminal images |
| US9286673B2 (en) | 2012-10-05 | 2016-03-15 | Volcano Corporation | Systems for correcting distortions in a medical image and methods of use thereof |
| US10568586B2 (en) | 2012-10-05 | 2020-02-25 | Volcano Corporation | Systems for indicating parameters in an imaging data set and methods of use |
| US9307926B2 (en) | 2012-10-05 | 2016-04-12 | Volcano Corporation | Automatic stent detection |
| US9858668B2 (en) | 2012-10-05 | 2018-01-02 | Volcano Corporation | Guidewire artifact removal in images |
| JP2015532536A (ja) | 2012-10-05 | 2015-11-09 | デイビッド ウェルフォード， | 光を増幅するためのシステムおよび方法 |
| US9324141B2 (en) | 2012-10-05 | 2016-04-26 | Volcano Corporation | Removal of A-scan streaking artifact |
| US9367965B2 (en) | 2012-10-05 | 2016-06-14 | Volcano Corporation | Systems and methods for generating images of tissue |
| US9840734B2 (en) | 2012-10-22 | 2017-12-12 | Raindance Technologies, Inc. | Methods for analyzing DNA |
| WO2014078700A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| WO2014080060A1 (es) * | 2012-11-23 | 2014-05-30 | Servicio Andaluz De Salud | Método para predecir la respuesta al tratamiento con quimioterapia en pacientes con cáncer |
| CA2894403A1 (en) | 2012-12-13 | 2014-06-19 | Volcano Corporation | Devices, systems, and methods for targeted cannulation |
| CA2895770A1 (en) | 2012-12-20 | 2014-07-24 | Jeremy Stigall | Locating intravascular images |
| US10939826B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Aspirating and removing biological material |
| CA2895989A1 (en) | 2012-12-20 | 2014-07-10 | Nathaniel J. Kemp | Optical coherence tomography system that is reconfigurable between different imaging modes |
| US10942022B2 (en) | 2012-12-20 | 2021-03-09 | Philips Image Guided Therapy Corporation | Manual calibration of imaging system |
| CA2895502A1 (en) | 2012-12-20 | 2014-06-26 | Jeremy Stigall | Smooth transition catheters |
| US11406498B2 (en) | 2012-12-20 | 2022-08-09 | Philips Image Guided Therapy Corporation | Implant delivery system and implants |
| WO2014100530A1 (en) | 2012-12-21 | 2014-06-26 | Whiseant Chester | System and method for catheter steering and operation |
| EP2934280B1 (en) | 2012-12-21 | 2022-10-19 | Mai, Jerome | Ultrasound imaging with variable line density |
| JP2016508757A (ja) | 2012-12-21 | 2016-03-24 | ジェイソン スペンサー， | 医療データのグラフィカル処理のためのシステムおよび方法 |
| US9612105B2 (en) | 2012-12-21 | 2017-04-04 | Volcano Corporation | Polarization sensitive optical coherence tomography system |
| EP2934323A4 (en) | 2012-12-21 | 2016-08-17 | Andrew Hancock | SYSTEM AND METHOD FOR MULTI-PASS PROCESSING OF IMAGE SIGNALS |
| JP2016508233A (ja) | 2012-12-21 | 2016-03-17 | ナサニエル ジェイ． ケンプ， | 光学スイッチを用いた電力効率のよい光学バッファリング |
| EP2936626A4 (en) | 2012-12-21 | 2016-08-17 | David Welford | SYSTEMS AND METHODS FOR REDUCING LIGHT WAVE LENGTH TRANSMISSION |
| WO2014100606A1 (en) | 2012-12-21 | 2014-06-26 | Meyer, Douglas | Rotational ultrasound imaging catheter with extended catheter body telescope |
| US9486143B2 (en) | 2012-12-21 | 2016-11-08 | Volcano Corporation | Intravascular forward imaging device |
| US10058284B2 (en) | 2012-12-21 | 2018-08-28 | Volcano Corporation | Simultaneous imaging, monitoring, and therapy |
| US10226597B2 (en) | 2013-03-07 | 2019-03-12 | Volcano Corporation | Guidewire with centering mechanism |
| EP2965263B1 (en) | 2013-03-07 | 2022-07-20 | Bernhard Sturm | Multimodal segmentation in intravascular images |
| US11154313B2 (en) | 2013-03-12 | 2021-10-26 | The Volcano Corporation | Vibrating guidewire torquer and methods of use |
| CN105228518B (zh) | 2013-03-12 | 2018-10-09 | 火山公司 | 用于诊断冠状微脉管疾病的系统和方法 |
| US11026591B2 (en) | 2013-03-13 | 2021-06-08 | Philips Image Guided Therapy Corporation | Intravascular pressure sensor calibration |
| CN105120759B (zh) | 2013-03-13 | 2018-02-23 | 火山公司 | 用于从旋转血管内超声设备产生图像的系统和方法 |
| US9301687B2 (en) | 2013-03-13 | 2016-04-05 | Volcano Corporation | System and method for OCT depth calibration |
| EP2967606B1 (en) | 2013-03-14 | 2018-05-16 | Volcano Corporation | Filters with echogenic characteristics |
| US10292677B2 (en) | 2013-03-14 | 2019-05-21 | Volcano Corporation | Endoluminal filter having enhanced echogenic properties |
| US10219887B2 (en) | 2013-03-14 | 2019-03-05 | Volcano Corporation | Filters with echogenic characteristics |
| CN103290134B (zh) * | 2013-06-21 | 2015-04-22 | 中国农业科学院兰州畜牧与兽药研究所 | 牛actb基因转录水平荧光定量pcr检测试剂盒 |
| JP6492100B2 (ja) | 2013-11-15 | 2019-03-27 | ノースカロライナ ステート ユニヴァーシティNorth Carolina State University | イヌの泌尿生殖器悪性腫瘍を診断する為の染色体評価 |
| US10501806B2 (en) | 2014-04-15 | 2019-12-10 | North Carolina State University | Chromosomal assessment to differentiate histiocytic malignancy from lymphoma in dogs |
| WO2015175692A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US10513738B2 (en) | 2014-07-24 | 2019-12-24 | North Carolina State University | Method to diagnose malignant melanoma in the domestic dog |
| CN104263723B (zh) * | 2014-09-15 | 2017-06-06 | 南京医科大学 | 一种与原发性肺癌辅助诊断相关的低频高外显性遗传标志物及其应用 |
| DK3210142T3 (da) | 2014-10-24 | 2020-11-16 | Koninklijke Philips Nv | Vurdering af tgf-cellulær signaleringsvejaktivitet under anvendelse af matematisk modellering af målgenekspression |
| EP3210144B1 (en) | 2014-10-24 | 2020-10-21 | Koninklijke Philips N.V. | Medical prognosis and prediction of treatment response using multiple cellular signaling pathway activities |
| ES2857953T3 (es) | 2014-10-24 | 2021-09-29 | Koninklijke Philips Nv | Pronóstico médico y predicción de la respuesta al tratamiento usando las actividades de múltiples rutas de señalización celular |
| AU2016309659A1 (en) | 2015-08-14 | 2018-04-12 | Koninklijke Philips N.V. | Assessment of NFkB cellular signaling pathway activity using mathematical modelling of target gene expression |
| US11066466B2 (en) * | 2016-04-14 | 2021-07-20 | Academia Sinica | Inhibition of SCUBE2, a novel VEGFR2 co-receptor, suppresses tumor angiogenesis |
| EP3464640B1 (en) | 2016-05-31 | 2021-06-30 | North Carolina State University | Methods of mast cell tumor prognosis and uses thereof |
| US20200315996A1 (en) * | 2016-06-02 | 2020-10-08 | Board Of Trustees, Southern Illinois University | Treatment of Endometriosis and Niclosamide Derivatives |
| CA3058406A1 (en) * | 2017-03-30 | 2018-10-04 | The Board Of Trustees Of The University Of Illinois | Method and kit for diagnosing early stage pancreatic cancer |
| EP3461915A1 (en) | 2017-10-02 | 2019-04-03 | Koninklijke Philips N.V. | Assessment of jak-stat1/2 cellular signaling pathway activity using mathematical modelling of target gene expression |
| EP3502279A1 (en) | 2017-12-20 | 2019-06-26 | Koninklijke Philips N.V. | Assessment of mapk-ap 1 cellular signaling pathway activity using mathematical modelling of target gene expression |
| WO2020226333A1 (ko) | 2019-05-03 | 2020-11-12 | 주식회사 디시젠 | 암 예후 예측방법 및 이의 조성물 |
| US20220357328A1 (en) * | 2019-09-09 | 2022-11-10 | Oaklabs Gmbh | Superior biomarker signature to predict the response of a breast cancer patient to chemotherapy |
| CN112725444A (zh) * | 2020-12-30 | 2021-04-30 | 杭州联川基因诊断技术有限公司 | 一种检测pgr基因表达的引物、探针、试剂盒和检测方法 |
Family Cites Families (82)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE56509B1 (en) | 1982-11-04 | 1991-08-28 | Univ California | Methods for oncogenic detection |
| USRE35491E (en) * | 1982-11-04 | 1997-04-08 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US4699877A (en) * | 1982-11-04 | 1987-10-13 | The Regents Of The University Of California | Methods and compositions for detecting human tumors |
| US7838216B1 (en) * | 1986-03-05 | 2010-11-23 | The United States Of America, As Represented By The Department Of Health And Human Services | Human gene related to but distinct from EGF receptor gene |
| US5015568A (en) * | 1986-07-09 | 1991-05-14 | The Wistar Institute | Diagnostic methods for detecting lymphomas in humans |
| US5202429A (en) | 1986-07-09 | 1993-04-13 | The Wistar Institute | DNA molecules having human BCL-2 gene sequences |
| US4968603A (en) | 1986-12-31 | 1990-11-06 | The Regents Of The University Of California | Determination of status in neoplastic disease |
| US5831066A (en) * | 1988-12-22 | 1998-11-03 | The Trustees Of The University Of Pennsylvania | Regulation of bcl-2 gene expression |
| US5858678A (en) * | 1994-08-02 | 1999-01-12 | St. Louis University | Apoptosis-regulating proteins |
| US5830753A (en) | 1994-09-30 | 1998-11-03 | Ludwig Institute For Cancer Research | Isolated nucleic acid molecules coding for tumor rejection antigen precursor dage and uses thereof. |
| ATE315654T1 (de) | 1995-12-18 | 2006-02-15 | Sugen Inc | Diagnose und behandlung von mit aur-1 und/oder aur-2 assoziierten erkrankungen |
| US6716575B2 (en) | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| US5670325A (en) | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| US5741650A (en) | 1996-01-30 | 1998-04-21 | Exact Laboratories, Inc. | Methods for detecting colon cancer from stool samples |
| US5821082A (en) * | 1996-05-23 | 1998-10-13 | St. Louis University Health Sciences Center | Anti-proliferation domain of a human Bcl-2 and DNA encoding the same |
| US6100029A (en) | 1996-08-14 | 2000-08-08 | Exact Laboratories, Inc. | Methods for the detection of chromosomal aberrations |
| US6143529A (en) | 1996-08-14 | 2000-11-07 | Exact Laboratories, Inc. | Methods for improving sensitivity and specificity of screening assays |
| US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US6146828A (en) | 1996-08-14 | 2000-11-14 | Exact Laboratories, Inc. | Methods for detecting differences in RNA expression levels and uses therefor |
| US5952178A (en) | 1996-08-14 | 1999-09-14 | Exact Laboratories | Methods for disease diagnosis from stool samples |
| US6203993B1 (en) | 1996-08-14 | 2001-03-20 | Exact Science Corp. | Methods for the detection of nucleic acids |
| US6020137A (en) | 1996-08-14 | 2000-02-01 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| US5861278A (en) | 1996-11-01 | 1999-01-19 | Genetics Institute, Inc. | HNF3δ compositions |
| DE69739105D1 (de) | 1996-11-20 | 2008-12-24 | Univ Yale | Survivin, ein protein das zelluläre apoptosis hemmt, und dessen modulation |
| US5830665A (en) | 1997-03-03 | 1998-11-03 | Exact Laboratories, Inc. | Contiguous genomic sequence scanning |
| US6033893A (en) | 1997-06-26 | 2000-03-07 | Incyte Pharmaceuticals, Inc. | Human cathepsin |
| WO1999002714A1 (en) | 1997-07-07 | 1999-01-21 | Abbott Laboratories | Reagents and methods useful for detecting diseases of the breast |
| US6020135A (en) | 1998-03-27 | 2000-02-01 | Affymetrix, Inc. | P53-regulated genes |
| JP2003528564A (ja) * | 1998-06-06 | 2003-09-30 | ジェノスティック ファーマ リミテッド | 遺伝的プロファイリングに使用するプローブ |
| US6696558B2 (en) | 1998-09-09 | 2004-02-24 | The Burnham Institute | Bag proteins and nucleic acid molecules encoding them |
| WO2000050595A2 (en) | 1999-02-25 | 2000-08-31 | Ivan Gout | Nucleic acid molecules associated with melanoma and thyroid tumors |
| US20020039764A1 (en) | 1999-03-12 | 2002-04-04 | Rosen Craig A. | Nucleic, acids, proteins, and antibodies |
| AU3395900A (en) | 1999-03-12 | 2000-10-04 | Human Genome Sciences, Inc. | Human lung cancer associated gene sequences and polypeptides |
| US6692916B2 (en) | 1999-06-28 | 2004-02-17 | Source Precision Medicine, Inc. | Systems and methods for characterizing a biological condition or agent using precision gene expression profiles |
| US6960439B2 (en) * | 1999-06-28 | 2005-11-01 | Source Precision Medicine, Inc. | Identification, monitoring and treatment of disease and characterization of biological condition using gene expression profiles |
| US6326148B1 (en) | 1999-07-12 | 2001-12-04 | The Regents Of The University Of California | Detection of copy number changes in colon cancer |
| US6710170B2 (en) | 1999-09-10 | 2004-03-23 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of ovarian cancer |
| US6271002B1 (en) * | 1999-10-04 | 2001-08-07 | Rosetta Inpharmatics, Inc. | RNA amplification method |
| AU777096B2 (en) | 1999-10-06 | 2004-09-30 | Regents Of The University Of California, The | Differentially expressed genes associated with Her-2/neu overexpression |
| CA2391455A1 (en) | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6750013B2 (en) | 1999-12-02 | 2004-06-15 | Protein Design Labs, Inc. | Methods for detection and diagnosing of breast cancer |
| US6248535B1 (en) | 1999-12-20 | 2001-06-19 | University Of Southern California | Method for isolation of RNA from formalin-fixed paraffin-embedded tissue specimens |
| WO2001051661A2 (en) * | 2000-01-13 | 2001-07-19 | Amsterdam Support Diagnostics B.V. | A universal nucleic acid amplification system for nucleic acids in a sample |
| US6322986B1 (en) * | 2000-01-18 | 2001-11-27 | Albany Medical College | Method for colorectal cancer prognosis and treatment selection |
| WO2001055454A1 (en) * | 2000-01-28 | 2001-08-02 | Althea Technologies, Inc. | Methods for analysis of gene expression |
| WO2001059064A2 (en) | 2000-01-31 | 2001-08-16 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| WO2001070979A2 (en) | 2000-03-21 | 2001-09-27 | Millennium Pharmaceuticals, Inc. | Genes, compositions, kits, and method for identification, assessment, prevention and therapy of ovarian cancer |
| AU2001251086A1 (en) * | 2000-03-31 | 2001-10-15 | Sir Mortimer B. Davis Jewish General Hospital | Microchip arrays of regulatory genes |
| AU2001266787A1 (en) | 2000-06-07 | 2002-01-08 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| US20030165952A1 (en) * | 2000-07-21 | 2003-09-04 | Sten Linnarsson | Method and an alggorithm for mrna expression analysis |
| AU2001278011A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ecg1 protein and related reagents and methods of use thereof |
| AU2001277202A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Bstp-ras/rerg protein and related reagents and methods of use thereof |
| AU2001278070A1 (en) | 2000-07-26 | 2002-02-05 | Applied Genomics, Inc. | Basal cell markers in breast cancer and uses thereof |
| US7795232B1 (en) | 2000-08-25 | 2010-09-14 | Genta Incorporated | Methods of treatment of a bcl-2 disorder using bcl-2 antisense oligomers |
| US6582919B2 (en) * | 2001-06-11 | 2003-06-24 | Response Genetics, Inc. | Method of determining epidermal growth factor receptor and HER2-neu gene expression and correlation of levels thereof with survival rates |
| US6602670B2 (en) * | 2000-12-01 | 2003-08-05 | Response Genetics, Inc. | Method of determining a chemotherapeutic regimen based on ERCC1 expression |
| US20030143539A1 (en) | 2000-12-08 | 2003-07-31 | Francois Bertucci | Gene expression profiling of primary breast carcinomas using arrays of candidate genes |
| AU2002255478A1 (en) | 2001-01-10 | 2002-09-12 | Pe Corporation (Ny) | Kits, such as nucleic acid arrays, comprising a majority of human exons or transcripts, for detecting expression and other uses thereof |
| EP1350114A2 (en) | 2001-01-12 | 2003-10-08 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| US7776518B2 (en) | 2001-01-12 | 2010-08-17 | Yale University | Detection of survivin in the biological fluids of cancer patients |
| MXPA03006617A (es) | 2001-01-24 | 2004-12-02 | Protein Design Labs Inc | Metodos de diagnostico de cancer de pecho, composiciones y metodos de rastreo de moduladores de cancer de pecho. |
| IL157872A0 (en) * | 2001-03-12 | 2004-03-28 | Monogen Inc | A panel for detecting a generic disease state containing a plurality of probes and using cell-based diagnosis |
| US7514209B2 (en) | 2001-06-18 | 2009-04-07 | Rosetta Inpharmatics Llc | Diagnosis and prognosis of breast cancer patients |
| WO2003011897A1 (en) | 2001-07-27 | 2003-02-13 | The Regents Of The University Of California | Modulation of heregulin and her3 interaction |
| AU2002343443A1 (en) * | 2001-09-28 | 2003-04-14 | Whitehead Institute For Biomedical Research | Classification of lung carcinomas using gene expression analysis |
| KR20040064275A (ko) | 2001-11-09 | 2004-07-16 | 소스 프리시전 메디슨, 인코포레이티드 | 유전자 발현 프로파일을 이용한 질병의 동정, 모니터링,치료 및 생물학적 상태의 확인 |
| US20030198972A1 (en) | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| EP3115470B1 (en) * | 2002-03-13 | 2018-07-18 | Genomic Health, Inc. | Gene expression profiling in biopsied tumor tissues |
| EP1492871A2 (en) | 2002-03-28 | 2005-01-05 | QLT Inc. | Cancer associated protein kinases and their uses |
| EP1900827A3 (en) | 2002-05-21 | 2008-04-16 | Bayer HealthCare AG | Methods and compositions for the prediction, diagnosis, prognosis, prevention and treatment of malignant neoplasia |
| JP4606879B2 (ja) * | 2002-11-15 | 2011-01-05 | ジェノミック ヘルス， インコーポレイテッド | Ｅｇｆｒ陽性癌の遺伝子発現プロファイリング |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| CA2527285A1 (en) * | 2003-05-28 | 2004-12-23 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| EP3470535B1 (en) * | 2003-06-24 | 2020-04-01 | Genomic Health, Inc. | Prediction of likelihood of cancer recurrence |
| WO2005008213A2 (en) * | 2003-07-10 | 2005-01-27 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| ES2550614T3 (es) * | 2004-04-09 | 2015-11-11 | Genomic Health, Inc. | Marcadores de expresión génica para predecir la respuesta a la quimioterapia |
| WO2006052731A2 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| CA3061785A1 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| US7888019B2 (en) * | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| CA2694703A1 (en) * | 2007-08-16 | 2009-02-26 | Aventis Inc. | Gene expression markers of recurrence risk in cancer patients after chemotherapy |
| EP2641978A1 (en) * | 2008-05-12 | 2013-09-25 | Genomic Health, Inc. | Tests to predict responsiveness of cancer patients to chemotherapy treatment options |
| US20110123990A1 (en) * | 2009-11-23 | 2011-05-26 | Baker Joffre B | Methods To Predict Clinical Outcome Of Cancer |
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| IL182929A (en) | 2011-11-30 |
| US8868352B2 (en) | 2014-10-21 |
| US7930104B2 (en) | 2011-04-19 |
| ES2778851T3 (es) | 2020-08-12 |
| PL1836629T3 (pl) | 2020-06-15 |
| JP5020088B2 (ja) | 2012-09-05 |
| EP1836629A1 (en) | 2007-09-26 |
| CA2585571A1 (en) | 2006-05-18 |
| WO2006052862A1 (en) | 2006-05-18 |
| AU2005304824A1 (en) | 2006-05-18 |
| CA2585571C (en) | 2020-01-21 |
| IL182929A0 (en) | 2007-09-20 |
| CA3061785A1 (en) | 2006-05-18 |
| EP1836629B1 (en) | 2020-03-04 |
| DK1836629T3 (da) | 2020-05-18 |
| US20060166230A1 (en) | 2006-07-27 |
| US20110178374A1 (en) | 2011-07-21 |
| US20150079591A1 (en) | 2015-03-19 |
| JP2008520192A (ja) | 2008-06-19 |
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