NO982794L - Diagnostisering og behandling av AUR-1 og/eller AUR-2 relaterte lidelser - Google Patents
Diagnostisering og behandling av AUR-1 og/eller AUR-2 relaterte lidelserInfo
- Publication number
- NO982794L NO982794L NO982794A NO982794A NO982794L NO 982794 L NO982794 L NO 982794L NO 982794 A NO982794 A NO 982794A NO 982794 A NO982794 A NO 982794A NO 982794 L NO982794 L NO 982794L
- Authority
- NO
- Norway
- Prior art keywords
- aur
- polypeptides
- diagnosis
- treatment
- related disorders
- Prior art date
Links
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Steroid Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US880995P | 1995-12-18 | 1995-12-18 | |
| US2394396P | 1996-08-14 | 1996-08-14 | |
| PCT/US1996/018859 WO1997022702A1 (en) | 1995-12-18 | 1996-11-25 | Diagnosis and treatment of aur-1 and/or aur-2 related disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO982794D0 NO982794D0 (no) | 1998-06-17 |
| NO982794L true NO982794L (no) | 1998-08-18 |
| NO323646B1 NO323646B1 (no) | 2007-06-18 |
Family
ID=26678652
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19982794A NO323646B1 (no) | 1995-12-18 | 1998-06-17 | Nukleinsyremolekyl, nukleinsyreprobe, polypeptid, antistoff, hybridom, kit, anvendelse samt fremgangsmate. |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5962312A (no) |
| EP (2) | EP1655369A1 (no) |
| JP (1) | JP3944241B2 (no) |
| KR (1) | KR100459052B1 (no) |
| AT (1) | ATE315654T1 (no) |
| AU (1) | AU716330B2 (no) |
| CA (1) | CA2239692C (no) |
| DE (1) | DE69635740T2 (no) |
| DK (1) | DK0868519T3 (no) |
| ES (1) | ES2255715T3 (no) |
| IL (1) | IL124728A (no) |
| NO (1) | NO323646B1 (no) |
| NZ (1) | NZ323795A (no) |
| PT (1) | PT868519E (no) |
| WO (1) | WO1997022702A1 (no) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716575B2 (en) * | 1995-12-18 | 2004-04-06 | Sugen, Inc. | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| US6759212B1 (en) * | 1997-08-15 | 2004-07-06 | Chugai Seiyaku Kabushiki Kaisha | Cell cycle-regulating proteins |
| US5962232A (en) * | 1998-01-30 | 1999-10-05 | Incyte Pharmaceuticals, Inc. | Protein kinase molecules |
| WO2001021596A1 (en) * | 1999-09-21 | 2001-03-29 | Astrazeneca Ab | Quinazoline derivatives and their use as pharmaceuticals |
| US6352858B1 (en) | 2000-09-11 | 2002-03-05 | Isis Pharmaceuticals, Inc. | Antisense modulation of BTAK expression |
| JP2002236125A (ja) * | 2001-02-06 | 2002-08-23 | Igaku Seibutsugaku Kenkyusho:Kk | タンパク質リン酸化酵素活性の測定方法、測定用キット及び測定に用いる抗体 |
| US6872533B2 (en) | 2001-07-27 | 2005-03-29 | The Regents Of The University Of California | STK15 (STK6) gene polymorphism and methods of determining cancer risk |
| AU2003215460A1 (en) * | 2002-03-28 | 2003-10-13 | Qlt Inc. | Cancer associated protein kinases and their uses |
| FR2840905B1 (fr) * | 2002-06-12 | 2006-07-07 | Centre Nat Rech Scient | Anticorps monoclonal anti-aurora-a, son procede d'obtention, et ses utilisations dans le diagnostic et le traitement des cancers |
| US7444273B1 (en) * | 2002-06-21 | 2008-10-28 | Takeda San Diego, Inc. | Crystallization of aurora/LPL1P-related kinase |
| DE60335636D1 (de) * | 2002-09-11 | 2011-02-17 | Genentech Inc | Zusammensetzungen und verfahren für die tumordiagnose und behandlung |
| JP4606879B2 (ja) * | 2002-11-15 | 2011-01-05 | ジェノミック ヘルス， インコーポレイテッド | Ｅｇｆｒ陽性癌の遺伝子発現プロファイリング |
| DK1847539T3 (da) | 2002-12-24 | 2009-11-09 | Astrazeneca Ab | Quinazolin-derivater |
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| WO2004071572A2 (en) * | 2003-02-06 | 2004-08-26 | Genomic Health, Inc. | Gene expression markers for response to egfr inhibitor drugs |
| ATE412779T1 (de) * | 2003-02-20 | 2008-11-15 | Genomic Health Inc | Benutzung von intronischen rna sequenzen zur quantifizierung der genexpression |
| US20050164218A1 (en) * | 2003-05-30 | 2005-07-28 | David Agus | Gene expression markers for response to EGFR inhibitor drugs |
| ES2609234T3 (es) | 2003-06-24 | 2017-04-19 | Genomic Health, Inc. | Predicción de la probabilidad de recidiva de cáncer |
| CA2531967C (en) * | 2003-07-10 | 2013-07-16 | Genomic Health, Inc. | Expression profile algorithm and test for cancer prognosis |
| US20050095634A1 (en) * | 2003-10-16 | 2005-05-05 | Genomic Health Inc. | qRT-PCR assay system for gene expression profiling |
| EP1694686A1 (en) | 2003-12-19 | 2006-08-30 | Takeda San Diego, Inc. | Kinase inhibitors |
| ATE498022T1 (de) * | 2003-12-23 | 2011-02-15 | Genomic Health Inc | Universelle vervielfältigung von fragmentierter rns |
| WO2005100606A2 (en) * | 2004-04-09 | 2005-10-27 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| CA2566531A1 (en) | 2004-05-18 | 2005-12-15 | Rigel Pharmaceuticals, Inc. | Cycloalkyl substituted pyrimidinediamine compounds and their uses |
| WO2006031273A2 (en) * | 2004-06-18 | 2006-03-23 | Cytokinetics, Inc. | Cellular phenotype |
| US7550598B2 (en) | 2004-08-18 | 2009-06-23 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| US7285569B2 (en) | 2004-09-24 | 2007-10-23 | Hoff Hoffmann-La Roche Inc. | Tricycles, their manufacture and use as pharmaceutical agents |
| AR050948A1 (es) | 2004-09-24 | 2006-12-06 | Hoffmann La Roche | Derivados de ftalazinona; su obtencion y su utilizacion en la fabricacion de medicamentos para el tratamiento del cancer. |
| US7713973B2 (en) | 2004-10-15 | 2010-05-11 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| WO2006052862A1 (en) * | 2004-11-05 | 2006-05-18 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| AU2005304878B2 (en) * | 2004-11-05 | 2010-07-08 | Genomic Health, Inc. | Molecular indicators of breast cancer prognosis and prediction of treatment response |
| GB2420559B (en) * | 2004-11-15 | 2008-08-06 | Rigel Pharmaceuticals Inc | Stereoisomerically enriched 3-aminocarbonyl bicycloheptene pyrimidinediamine compounds and their uses |
| WO2006108489A1 (en) | 2005-04-14 | 2006-10-19 | F. Hoffmann-La Roche Ag | Aminopyrazole derivatives, their manufacture and use as pharmaceutical agents |
| US20070082327A1 (en) * | 2005-09-09 | 2007-04-12 | Cytokinetics, Inc. A Delaware Corporation | Cellular phenotype |
| US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
| WO2007079445A2 (en) * | 2006-01-03 | 2007-07-12 | Sunesis Pharmaceuticals, Inc. | Aurora expression constructs |
| SG175609A1 (en) | 2006-10-09 | 2011-11-28 | Takeda Pharmaceutical | Kinase inhibitors |
| JP5279063B2 (ja) * | 2007-05-25 | 2013-09-04 | 国立大学法人愛媛大学 | Ｈｌａ−ａ２拘束性抗原ペプチドおよびその用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945050A (en) * | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
| US5283173A (en) * | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
| DE69232718T2 (de) * | 1991-02-22 | 2003-04-03 | American Cyanamid Co., Madison | Identifizierung eines menschlichen rezeptor-tyrosinkinasegens |
| CA2157774A1 (en) * | 1993-04-07 | 1994-10-13 | Christopher John Marshall | Methods for screening of substances for therapeutic activity and yeast for use therein |
| US5830648A (en) * | 1995-05-05 | 1998-11-03 | Sugen, Inc. | Assay and method for transcript imaging |
-
1996
- 1996-11-25 DK DK96940870T patent/DK0868519T3/da active
- 1996-11-25 WO PCT/US1996/018859 patent/WO1997022702A1/en active IP Right Grant
- 1996-11-25 CA CA002239692A patent/CA2239692C/en not_active Expired - Lifetime
- 1996-11-25 EP EP05023434A patent/EP1655369A1/en not_active Withdrawn
- 1996-11-25 JP JP52280797A patent/JP3944241B2/ja not_active Expired - Lifetime
- 1996-11-25 NZ NZ323795A patent/NZ323795A/xx unknown
- 1996-11-25 AU AU10826/97A patent/AU716330B2/en not_active Expired
- 1996-11-25 DE DE69635740T patent/DE69635740T2/de not_active Revoked
- 1996-11-25 IL IL124728A patent/IL124728A/en not_active IP Right Cessation
- 1996-11-25 US US08/755,728 patent/US5962312A/en not_active Expired - Lifetime
- 1996-11-25 PT PT96940870T patent/PT868519E/pt unknown
- 1996-11-25 ES ES96940870T patent/ES2255715T3/es not_active Expired - Lifetime
- 1996-11-25 EP EP96940870A patent/EP0868519B1/en not_active Revoked
- 1996-11-25 KR KR10-1998-0704572A patent/KR100459052B1/ko not_active IP Right Cessation
- 1996-11-25 AT AT96940870T patent/ATE315654T1/de active
-
1997
- 1997-11-19 US US08/974,655 patent/US5972676A/en not_active Expired - Lifetime
-
1998
- 1998-06-17 NO NO19982794A patent/NO323646B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US5972676A (en) | 1999-10-26 |
| EP0868519A1 (en) | 1998-10-07 |
| DK0868519T3 (da) | 2006-05-08 |
| US5962312A (en) | 1999-10-05 |
| IL124728A0 (en) | 1999-01-26 |
| WO1997022702A1 (en) | 1997-06-26 |
| NO982794D0 (no) | 1998-06-17 |
| CA2239692C (en) | 2008-12-16 |
| AU1082697A (en) | 1997-07-14 |
| JP3944241B2 (ja) | 2007-07-11 |
| ES2255715T3 (es) | 2006-07-01 |
| JP2000502895A (ja) | 2000-03-14 |
| CA2239692A1 (en) | 1997-06-26 |
| KR20000064437A (ko) | 2000-11-06 |
| EP0868519B1 (en) | 2006-01-11 |
| KR100459052B1 (ko) | 2005-01-15 |
| PT868519E (pt) | 2006-05-31 |
| NO323646B1 (no) | 2007-06-18 |
| DE69635740T2 (de) | 2006-09-14 |
| NZ323795A (en) | 2000-01-28 |
| DE69635740D1 (de) | 2006-04-06 |
| IL124728A (en) | 2007-06-03 |
| AU716330B2 (en) | 2000-02-24 |
| ATE315654T1 (de) | 2006-02-15 |
| EP1655369A1 (en) | 2006-05-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |