NO318783B1 - Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. - Google Patents
Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. Download PDFInfo
- Publication number
- NO318783B1 NO318783B1 NO19975729A NO975729A NO318783B1 NO 318783 B1 NO318783 B1 NO 318783B1 NO 19975729 A NO19975729 A NO 19975729A NO 975729 A NO975729 A NO 975729A NO 318783 B1 NO318783 B1 NO 318783B1
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- Prior art keywords
- peptide
- amino acid
- epo
- peptide according
- peptides
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/64—Cyclic peptides containing only normal peptide links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Dermatology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/484,635 US5773569A (en) | 1993-11-19 | 1995-06-07 | Compounds and peptides that bind to the erythropoietin receptor |
| US08/484,631 US5830851A (en) | 1993-11-19 | 1995-06-07 | Methods of administering peptides that bind to the erythropoietin receptor |
| PCT/US1996/009810 WO1996040749A1 (en) | 1995-06-07 | 1996-06-07 | Compounds and peptides that bind to the erythropoietin receptor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO975729D0 NO975729D0 (no) | 1997-12-05 |
| NO975729L NO975729L (no) | 1998-02-05 |
| NO318783B1 true NO318783B1 (no) | 2005-05-09 |
Family
ID=27048076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19975729A NO318783B1 (no) | 1995-06-07 | 1997-12-05 | Peptid som binder til erytropoietinreseptoren og anvendelse derav, samt farmasoytiske blandinger som inneholder peptidet. |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP1510524A3 (cs) |
| JP (3) | JP4050314B2 (cs) |
| KR (1) | KR100459984B1 (cs) |
| CN (1) | CN1192748A (cs) |
| AT (1) | ATE254138T1 (cs) |
| AU (1) | AU712713B2 (cs) |
| BR (1) | BR9609006A (cs) |
| CA (1) | CA2223833C (cs) |
| CZ (1) | CZ391097A3 (cs) |
| DE (1) | DE69630708T2 (cs) |
| ES (1) | ES2210374T3 (cs) |
| HU (1) | HUP9901069A2 (cs) |
| IL (1) | IL122417A0 (cs) |
| NO (1) | NO318783B1 (cs) |
| NZ (1) | NZ310804A (cs) |
| PL (1) | PL185040B1 (cs) |
| TR (1) | TR199701557T2 (cs) |
| WO (1) | WO1996040749A1 (cs) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830851A (en) * | 1993-11-19 | 1998-11-03 | Affymax Technologies N.V. | Methods of administering peptides that bind to the erythropoietin receptor |
| US5773569A (en) * | 1993-11-19 | 1998-06-30 | Affymax Technologies N.V. | Compounds and peptides that bind to the erythropoietin receptor |
| US5767078A (en) * | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
| US6121416A (en) * | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| DE19904396A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Substituierte Pyrazolbenzylamin-Derivate |
| DE19904406A1 (de) * | 1999-02-04 | 2000-08-10 | Bayer Ag | Substituierte Pyrazolcarbonsäuren |
| US6703480B1 (en) | 1999-11-24 | 2004-03-09 | Palani Balu | Peptide dimers as agonists of the erythropoientin (EPO) receptor, and associated methods of synthesis and use |
| US7259146B2 (en) | 2000-05-26 | 2007-08-21 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective peptides |
| GB0208742D0 (en) | 2002-04-17 | 2002-05-29 | Bradford Particle Design Ltd | Particulate materials |
| US7208145B2 (en) | 2002-12-31 | 2007-04-24 | Nektar Therapeutics Al, Corporation | Polymeric reagents comprising a ketone or a related functional group |
| KR20060028675A (ko) | 2003-05-12 | 2006-03-31 | 아피맥스, 인크. | 신규한 폴리 (에틸렌 글리콜) 개질 화합물 및 그의 용도 |
| KR101163683B1 (ko) | 2003-05-12 | 2012-07-10 | 아피맥스, 인크. | 에리스로포이에틴 수용체에 결합하는 신규의 펩티드 |
| PT1625156E (pt) | 2003-05-12 | 2013-01-09 | Affymax Inc | Novos péptidos que se fixam ao receptor da eritropoietina |
| CN1849141A (zh) | 2003-05-12 | 2006-10-18 | 阿费麦克斯公司 | 用于聚(乙二醇)修饰的肽的间隔臂部分 |
| EP2644206B1 (en) | 2003-05-23 | 2019-04-03 | Nektar Therapeutics | PEG derivatives containing two PEG chains |
| SI1675622T1 (sl) | 2003-09-17 | 2017-09-29 | Nektar Therapeutics | Večkraka polimerna predzdravila |
| ES2733764T3 (es) | 2003-12-16 | 2019-12-02 | Nektar Therapeutics | Método para la preparación de oligo etilenglicol monodisperso |
| JP2007529475A (ja) * | 2004-03-17 | 2007-10-25 | アプラーゲン ゲゼルシャフト ミット ベシュレンクテル ハフツング | 等比体積の形態変換 |
| WO2005107815A2 (en) | 2004-05-03 | 2005-11-17 | Nektar Therapeutics Al, Corporation | Polymer derivatives comprising an imide branching point |
| WO2005108463A2 (en) | 2004-05-03 | 2005-11-17 | Nektar Therapeutics Al, Corporation | Branched polyethylen glycol derivates comprising an acetal or ketal branching point |
| US7589063B2 (en) | 2004-12-14 | 2009-09-15 | Aplagen Gmbh | Molecules which promote hematopoiesis |
| KR20070092706A (ko) * | 2004-11-10 | 2007-09-13 | 아플라겐 게엠베하 | 조혈을 촉진하는 분자 |
| AU2005310189A1 (en) * | 2004-11-11 | 2006-06-08 | Affymax, Inc. | Novel peptides that bind to the erythropoietin receptor |
| EP1884235A1 (en) * | 2005-04-26 | 2008-02-06 | Ajinomoto Co., Inc. | Myeloerythroid progenitor differentiation inducer |
| US7550433B2 (en) | 2005-06-03 | 2009-06-23 | Affymax, Inc. | Erythropoietin receptor peptide formulations and uses |
| CA2648732A1 (en) * | 2005-06-23 | 2006-12-28 | Aplagen Gmbh | Supravalent compounds |
| NZ565937A (en) * | 2005-08-05 | 2011-09-30 | Araim Pharmaceuticals Inc | Tissue protective peptides and uses thereof |
| JP2009529509A (ja) * | 2006-03-09 | 2009-08-20 | アプラゲン ゲーエムベーハー | 造血を促進する修飾分子 |
| CN101528263B (zh) | 2006-06-30 | 2013-01-23 | Sku资产管理有限公司 | 用于癌症的先天性免疫方法的缀合物 |
| JP2010520855A (ja) | 2007-01-31 | 2010-06-17 | アフィーマックス・インコーポレイテッド | 修飾基をポリペプチドおよびその他の高分子に結合するための窒素ベースのリンカー |
| EP2018835B1 (de) | 2007-07-09 | 2014-03-05 | Augustinus Bader | Wirkstoff abgebendes Pflaster |
| CN101456911A (zh) * | 2007-12-12 | 2009-06-17 | 江苏豪森药业股份有限公司 | 促红细胞生成素模拟肽衍生物及其可药用盐和其制备方法与用途 |
| US20110105400A1 (en) * | 2008-03-26 | 2011-05-05 | Orthologic Corp. | Methods for treating acute myocardial infarction |
| WO2010014258A2 (en) | 2008-08-01 | 2010-02-04 | Nektar Therapeutics Al, Corporation | Conjugates having a releasable linkage |
| EP2331140B1 (en) | 2008-08-11 | 2018-07-04 | Nektar Therapeutics | Multi-arm polymeric alkanoate conjugates |
| US8492503B2 (en) | 2008-09-11 | 2013-07-23 | Nektar Therapeutics | Polymeric alpha-hydroxy aldehyde and ketone reagents and conjugation method |
| WO2010033207A1 (en) | 2008-09-19 | 2010-03-25 | Nektar Therapeutics | Polymer conjugates of therapeutic peptides |
| PL2342223T3 (pl) * | 2008-09-26 | 2017-09-29 | Ambrx, Inc. | Zmodyfikowane polipeptydy zwierzęcej erytropoetyny i ich zastosowania |
| EP2443459B1 (en) * | 2009-06-19 | 2018-12-26 | The Arizona Board of Regents, A Body Corporate Of the State of Arizona acting for and on behalf Of Arizona State University | Compound arrays for sample profiling |
| WO2011012306A2 (en) | 2009-07-30 | 2011-02-03 | Aplagen Gmbh | Use of emps for antagonising epo-stimulatory effects on epo-responsive tumors while maintaining erythropoiesis |
| DK2590666T3 (en) | 2010-07-06 | 2017-07-17 | Augustinus Bader | TOPICAL APPLICATION OF ERYTHROPOIETIN FOR USE IN THE TREATMENT OF DAMAGE OF THE CORNS |
| US20130331443A1 (en) | 2010-12-22 | 2013-12-12 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of taxane-based compounds |
| WO2012088445A1 (en) | 2010-12-22 | 2012-06-28 | Nektar Therapeutics | Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds |
| WO2012166555A1 (en) | 2011-05-27 | 2012-12-06 | Nektar Therapeutics | Water - soluble polymer - linked binding moiety and drug compounds |
| WO2013171810A1 (ja) | 2012-05-14 | 2013-11-21 | パナソニック株式会社 | 耐熱性抗体提示ファージを得る方法 |
| CN103450348B (zh) * | 2012-05-29 | 2016-03-30 | 中国人民解放军军事医学科学院毒物药物研究所 | 一种促红细胞生成素模拟肽、其制备方法和用途 |
| CN106608906A (zh) * | 2015-10-22 | 2017-05-03 | 天津药物研究院有限公司 | 一种具有刺激红细胞生成功能的环形多肽的制备及其应用 |
| CN106928338A (zh) * | 2015-12-31 | 2017-07-07 | 杭州阿德莱诺泰制药技术有限公司 | 促红细胞生成素肽及衍生物和聚合物、制备方法和应用 |
| GB201609083D0 (en) | 2016-05-24 | 2016-07-06 | Syntab Therapeutics Gmbh | Synthetic compound |
| JP7445978B2 (ja) * | 2018-09-14 | 2024-03-08 | エポメッド株式会社 | 抗エリスロポエチン受容体ペプチド |
| KR20220019027A (ko) | 2019-06-10 | 2022-02-15 | 레스피라 테라퓨틱스 인크. | 담체-기반 제제 및 관련 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210501A (en) * | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| WO1990008822A1 (en) * | 1989-02-03 | 1990-08-09 | Genetics Institute, Inc. | Erythropoietin receptor |
| DE3924746A1 (de) * | 1989-07-26 | 1991-01-31 | Behringwerke Ag | Erythropoietin (epo)-peptide und dagegen gerichtete antikoerper |
| US5767078A (en) * | 1995-06-07 | 1998-06-16 | Johnson; Dana L. | Agonist peptide dimers |
-
1996
- 1996-06-07 BR BR9609006-5A patent/BR9609006A/pt unknown
- 1996-06-07 EP EP03025811A patent/EP1510524A3/en not_active Withdrawn
- 1996-06-07 AU AU61667/96A patent/AU712713B2/en not_active Ceased
- 1996-06-07 KR KR1019970709231A patent/KR100459984B1/ko not_active IP Right Cessation
- 1996-06-07 CN CN96196094A patent/CN1192748A/zh active Pending
- 1996-06-07 ES ES96919296T patent/ES2210374T3/es not_active Expired - Lifetime
- 1996-06-07 DE DE69630708T patent/DE69630708T2/de not_active Expired - Lifetime
- 1996-06-07 AT AT96919296T patent/ATE254138T1/de not_active IP Right Cessation
- 1996-06-07 CZ CZ973910A patent/CZ391097A3/cs unknown
- 1996-06-07 IL IL12241796A patent/IL122417A0/xx unknown
- 1996-06-07 PL PL96323858A patent/PL185040B1/pl not_active IP Right Cessation
- 1996-06-07 CA CA2223833A patent/CA2223833C/en not_active Expired - Fee Related
- 1996-06-07 WO PCT/US1996/009810 patent/WO1996040749A1/en active IP Right Grant
- 1996-06-07 EP EP96919296A patent/EP0886648B8/en not_active Expired - Lifetime
- 1996-06-07 NZ NZ310804A patent/NZ310804A/xx not_active IP Right Cessation
- 1996-06-07 HU HU9901069A patent/HUP9901069A2/hu unknown
- 1996-06-07 TR TR97/01557T patent/TR199701557T2/xx unknown
- 1996-06-07 JP JP50202397A patent/JP4050314B2/ja not_active Expired - Fee Related
-
1997
- 1997-12-05 NO NO19975729A patent/NO318783B1/no not_active IP Right Cessation
-
2007
- 2007-07-18 JP JP2007186814A patent/JP2007277264A/ja active Pending
-
2009
- 2009-08-31 JP JP2009200615A patent/JP2009280616A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| BR9609006A (pt) | 1999-12-14 |
| EP1510524A2 (en) | 2005-03-02 |
| EP1510524A3 (en) | 2006-06-07 |
| IL122417A0 (en) | 1998-06-15 |
| NO975729D0 (no) | 1997-12-05 |
| EP0886648A1 (en) | 1998-12-30 |
| EP0886648B1 (en) | 2003-11-12 |
| CZ391097A3 (cs) | 1998-07-15 |
| JP2009280616A (ja) | 2009-12-03 |
| TR199701557T2 (xx) | 2002-06-21 |
| JP4050314B2 (ja) | 2008-02-20 |
| EP0886648A4 (en) | 2000-01-12 |
| DE69630708D1 (de) | 2003-12-18 |
| JP2007277264A (ja) | 2007-10-25 |
| HUP9901069A2 (hu) | 1999-07-28 |
| KR100459984B1 (ko) | 2005-06-20 |
| EP0886648B8 (en) | 2004-03-03 |
| NZ310804A (en) | 1998-10-28 |
| PL185040B1 (pl) | 2003-02-28 |
| AU712713B2 (en) | 1999-11-11 |
| CA2223833C (en) | 2010-12-21 |
| NO975729L (no) | 1998-02-05 |
| AU6166796A (en) | 1996-12-30 |
| WO1996040749A1 (en) | 1996-12-19 |
| CA2223833A1 (en) | 1996-12-19 |
| KR19990022656A (ko) | 1999-03-25 |
| PL323858A1 (en) | 1998-04-27 |
| CN1192748A (zh) | 1998-09-09 |
| ATE254138T1 (de) | 2003-11-15 |
| ES2210374T3 (es) | 2004-07-01 |
| DE69630708T2 (de) | 2004-08-05 |
| JPH11507367A (ja) | 1999-06-29 |
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| MM1K | Lapsed by not paying the annual fees |