NO317103B1 - Nye substituerte pyridino arylpiperaziner er anvendelige ved behandling av benign prostata hyperplasi - Google Patents

Nye substituerte pyridino arylpiperaziner er anvendelige ved behandling av benign prostata hyperplasi Download PDF

Info

Publication number
NO317103B1
NO317103B1 NO20004141A NO20004141A NO317103B1 NO 317103 B1 NO317103 B1 NO 317103B1 NO 20004141 A NO20004141 A NO 20004141A NO 20004141 A NO20004141 A NO 20004141A NO 317103 B1 NO317103 B1 NO 317103B1
Authority
NO
Norway
Prior art keywords
hydrogen
mmol
compound
alkyl
mixture
Prior art date
Application number
NO20004141A
Other languages
English (en)
Norwegian (no)
Other versions
NO20004141D0 (no
NO20004141L (no
Inventor
William V Murray
Catherine P Prouty
Gee-Hong Kuo
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Publication of NO20004141D0 publication Critical patent/NO20004141D0/no
Publication of NO20004141L publication Critical patent/NO20004141L/no
Publication of NO317103B1 publication Critical patent/NO317103B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NO20004141A 1998-02-20 2000-08-18 Nye substituerte pyridino arylpiperaziner er anvendelige ved behandling av benign prostata hyperplasi NO317103B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7532198P 1998-02-20 1998-02-20
PCT/US1999/003608 WO1999042448A1 (en) 1998-02-20 1999-02-19 Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia

Publications (3)

Publication Number Publication Date
NO20004141D0 NO20004141D0 (no) 2000-08-18
NO20004141L NO20004141L (no) 2000-10-19
NO317103B1 true NO317103B1 (no) 2004-08-09

Family

ID=22124955

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20004141A NO317103B1 (no) 1998-02-20 2000-08-18 Nye substituerte pyridino arylpiperaziner er anvendelige ved behandling av benign prostata hyperplasi

Country Status (23)

Country Link
US (1) US6218396B1 (enExample)
EP (1) EP1054868B1 (enExample)
JP (1) JP2002503724A (enExample)
KR (1) KR100591028B1 (enExample)
CN (1) CN1121390C (enExample)
AR (1) AR014626A1 (enExample)
AT (1) ATE250580T1 (enExample)
AU (1) AU766398B2 (enExample)
BR (1) BR9909647A (enExample)
CZ (1) CZ294136B6 (enExample)
DE (1) DE69911582T2 (enExample)
DK (1) DK1054868T3 (enExample)
ES (1) ES2209468T3 (enExample)
HU (1) HUP0100781A3 (enExample)
IL (2) IL137954A0 (enExample)
NO (1) NO317103B1 (enExample)
NZ (1) NZ506462A (enExample)
PL (1) PL342339A1 (enExample)
PT (1) PT1054868E (enExample)
TR (1) TR200003220T2 (enExample)
TW (1) TW565555B (enExample)
WO (1) WO1999042448A1 (enExample)
ZA (1) ZA991315B (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998051298A1 (en) * 1997-05-12 1998-11-19 Ortho-Mcneil Pharmaceutical Inc. Arylsubstituted piperazines useful in the treatement of benign prostatic hyperlasia
MXPA03001268A (es) 2000-08-08 2004-09-06 Johnson & Johnson Ariloxipiperidinas sin imidazol.
AU2002367425B2 (en) * 2001-12-28 2006-03-09 Takeda Pharmaceutical Company Limited Preventives/remedies for urinary disturbance
USD545208S1 (en) 2006-09-27 2007-06-26 001 Corporation Perfume bottle and cap
EP2077262A4 (en) * 2006-10-23 2011-12-28 Takeda Pharmaceutical IMINOPYRIDINE DERIVATIVE AND USE THEREOF
US8481569B2 (en) 2008-04-23 2013-07-09 Takeda Pharmaceutical Company Limited Iminopyridine derivatives and use thereof
US20110039892A1 (en) * 2008-04-23 2011-02-17 Takeda Pharmaceutical Company Limited Iminopyridine derivative and use thereof
CN102066327B (zh) * 2008-04-23 2013-05-29 武田药品工业株式会社 亚氨基吡啶衍生物及其用途
CN103980195A (zh) * 2014-04-28 2014-08-13 广州医科大学 酰胺类苯基哌嗪衍生物及其盐与在制备治疗良性前列腺增生症药物中的应用
CN108530391B (zh) * 2018-05-17 2022-05-17 袁牧 一种酰胺类芳基哌嗪衍生物及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2027898A6 (es) * 1991-01-24 1992-06-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados de la 2-metoxifenilpiperacina.
US5403847A (en) 1992-11-13 1995-04-04 Synaptic Pharmaceutical Corporation Use of α1C specific compounds to treat benign prostatic hyperlasia
IT1266582B1 (it) * 1993-07-30 1997-01-09 Recordati Chem Pharm Derivati (di)azacicloesanici e diazacicloeptanici
DE4425146A1 (de) * 1994-07-15 1996-01-18 Basf Ag Verwendung heterocyclischer Verbindungen
US5688795A (en) * 1994-11-08 1997-11-18 Syntex (U.S.A.) Inc. 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy!-pyridine, pyrimidine and benzene derivatives as α1 -adrenoceptor antagonists
AU8130298A (en) * 1997-07-15 1999-02-10 Sankyo Company Limited Piperazine derivatives

Also Published As

Publication number Publication date
TW565555B (en) 2003-12-11
EP1054868A1 (en) 2000-11-29
AU3302599A (en) 1999-09-06
HUP0100781A3 (en) 2002-12-28
PT1054868E (pt) 2004-01-30
IL137954A (en) 2007-06-03
NO20004141D0 (no) 2000-08-18
EP1054868B1 (en) 2003-09-24
CZ294136B6 (cs) 2004-10-13
PL342339A1 (en) 2001-06-04
AR014626A1 (es) 2001-03-28
ES2209468T3 (es) 2004-06-16
DE69911582D1 (de) 2003-10-30
KR20010041115A (ko) 2001-05-15
ATE250580T1 (de) 2003-10-15
JP2002503724A (ja) 2002-02-05
HUP0100781A2 (hu) 2001-08-28
NZ506462A (en) 2003-07-25
KR100591028B1 (ko) 2006-06-22
US6218396B1 (en) 2001-04-17
TR200003220T2 (tr) 2001-04-20
WO1999042448A1 (en) 1999-08-26
BR9909647A (pt) 2000-11-21
CN1121390C (zh) 2003-09-17
CN1291188A (zh) 2001-04-11
CZ20003044A3 (cs) 2001-04-11
AU766398B2 (en) 2003-10-16
DE69911582T2 (de) 2005-09-15
ZA991315B (en) 2000-11-20
DK1054868T3 (da) 2003-12-22
NO20004141L (no) 2000-10-19
IL137954A0 (en) 2001-10-31
HK1030776A1 (en) 2001-05-18

Similar Documents

Publication Publication Date Title
NO317103B1 (no) Nye substituerte pyridino arylpiperaziner er anvendelige ved behandling av benign prostata hyperplasi
EP1025085B1 (en) Heterocycles useful in the treatment of benign prostatic hyperplasia and intermediates thereof
NO317104B1 (no) Ftalimidoarylpiperaziner som <alfa> 1A reseptorantagonister anvendelige ved behandling av benign prostata hyperplasi, og farmasoytisk sammensetning innbefattende samme
US6063785A (en) Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia
US6362338B1 (en) Phthalimido arylpiperazines useful in the treatment of benign prostatic hyperplasia
MXPA00008220A (en) Novel substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia
HK1030776B (en) Substituted pyridino arylpiperazines useful in the treatment of benign prostatic hyperplasia
EP1346983A2 (en) Phthalimido arylpiperazines as alpha 1A receptor antagonists useful in the treatment of benign prostatic hyperplasia
MXPA00008219A (en) Phtalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasia
CZ20003045A3 (cs) Ftalimidoarylpiperaziny jako antagonisty alfa IA receptorů použitelné při léčení benigního zbytnění prostaty
HK1031872B (en) Phtalimido arylpiperazines as alpha 1a receptor antagonists useful in the treatment of benign prostatic hyperplasia
HK1026701B (en) Heterocycles useful in the treatment of benign prostatic hyperplasia and intermediates thereof

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees