NO315840B1 - Anvendelse av distrontiumsaltet av 2-[N,N- di(karboksymetyl)amino]-3-cyano-4-karboksymetyltiofen-5-karboksylsyre til fremstilling av etfarmasöytisk preparat for behandling av artrose - Google Patents

Anvendelse av distrontiumsaltet av 2-[N,N- di(karboksymetyl)amino]-3-cyano-4-karboksymetyltiofen-5-karboksylsyre til fremstilling av etfarmasöytisk preparat for behandling av artrose Download PDF

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Publication number
NO315840B1
NO315840B1 NO19972764A NO972764A NO315840B1 NO 315840 B1 NO315840 B1 NO 315840B1 NO 19972764 A NO19972764 A NO 19972764A NO 972764 A NO972764 A NO 972764A NO 315840 B1 NO315840 B1 NO 315840B1
Authority
NO
Norway
Prior art keywords
treatment
carboxymethyl
cyano
amino
preparation
Prior art date
Application number
NO19972764A
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English (en)
Norwegian (no)
Other versions
NO972764D0 (no
NO972764L (no
Inventor
Yannis Tsouderos
Pascale Deloffre
Michel Wierzbicki
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO972764D0 publication Critical patent/NO972764D0/no
Publication of NO972764L publication Critical patent/NO972764L/no
Publication of NO315840B1 publication Critical patent/NO315840B1/no

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Medicinal Preparation (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
NO19972764A 1996-06-17 1997-06-16 Anvendelse av distrontiumsaltet av 2-[N,N- di(karboksymetyl)amino]-3-cyano-4-karboksymetyltiofen-5-karboksylsyre til fremstilling av etfarmasöytisk preparat for behandling av artrose NO315840B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9607475A FR2749759B1 (fr) 1996-06-17 1996-06-17 Utilisation de sels de strontium pour l'obtention de compositions pharmaceutiques destinees au traitement de l'arthrose

Publications (3)

Publication Number Publication Date
NO972764D0 NO972764D0 (no) 1997-06-16
NO972764L NO972764L (no) 1997-12-18
NO315840B1 true NO315840B1 (no) 2003-11-03

Family

ID=9493102

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19972764A NO315840B1 (no) 1996-06-17 1997-06-16 Anvendelse av distrontiumsaltet av 2-[N,N- di(karboksymetyl)amino]-3-cyano-4-karboksymetyltiofen-5-karboksylsyre til fremstilling av etfarmasöytisk preparat for behandling av artrose

Country Status (16)

Country Link
US (1) US5856356A (hu)
EP (1) EP0813869B1 (hu)
JP (1) JP3935557B2 (hu)
CN (1) CN1136856C (hu)
AT (1) ATE233558T1 (hu)
AU (1) AU711950B2 (hu)
BR (1) BR9703603A (hu)
CA (1) CA2206837C (hu)
DE (1) DE69719408T2 (hu)
DK (1) DK0813869T3 (hu)
ES (1) ES2193337T3 (hu)
FR (1) FR2749759B1 (hu)
HU (1) HU227935B1 (hu)
NO (1) NO315840B1 (hu)
NZ (1) NZ328106A (hu)
ZA (1) ZA975323B (hu)

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FR2844797B1 (fr) * 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel des tetraesters de l'acide 5-[bis (carboxymethyl)]-3-carboxymethyl-4-cyano-2- thiophenecarboxylique, et application a la synthese des sels bivalents de l'acide ranelique et de leurs hydrates
FR2844795B1 (fr) * 2002-09-24 2004-10-22 Servier Lab Nouveau procede de synthese industriel du ranelate de strontium et de ses hydrates
FR2846558B1 (fr) * 2002-11-05 2006-07-14 Servier Lab Utilisation du sel distrontique de l'acide 2-n,n-di(carboxymethyl)amino-3-cyano-4-carboxymethyl- thiophene-5-carboxylique pour l'obtention de medicaments destines au traitement des douleurs gastro-duodenales
JP4750691B2 (ja) * 2003-03-27 2011-08-17 サントソルヴ エーエス 抗炎症治療
DK2266584T3 (da) * 2003-05-07 2013-01-02 Osteologix As Sammensætning med strontium og D-vitamin til profylakse og/eller behandling af brusk- og knogletilstande
AU2004237437B2 (en) * 2003-05-07 2011-01-20 Osteologix A/S Controlled release composition containing a strontium salt
DE602004002832T2 (de) * 2003-05-07 2007-06-06 Osteologix A/S Behandlung von knorpel/knochen-erkrankungen mit wasserlöslichen strontiumsalzen
US7927626B2 (en) 2003-08-07 2011-04-19 Ethicon, Inc. Process of making flowable hemostatic compositions and devices containing such compositions
AU2005216596B2 (en) * 2004-02-26 2011-03-24 Osteologix A/S Strontium-containing compounds for use in the prevention or treatment of necrotic bone conditions
EP1744770A2 (en) * 2004-05-06 2007-01-24 Osteologix A/S High yield and rapid syntheses methods for producing metallo-organic salts
CA2570503A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S A method of improving the medical treatment of pain
WO2006089546A1 (en) * 2005-02-28 2006-08-31 Osteologix A/S Tablets comprising a high load of strontium
CA2570389A1 (en) * 2004-06-17 2005-12-29 Osteologix A/S Treatments comprising strontium for rheumatic and arthritic diseases and pain
US7618651B2 (en) * 2004-06-24 2009-11-17 Idexx Laboratories Pharmaceutical compositions for drug delivery and methods of treating or preventing conditions using same
CN101018586B (zh) * 2004-06-25 2014-08-27 莫克瓦洛Spf有限公司 含锶和维生素d的组合物及其用途
EP1768748B2 (en) * 2004-06-25 2019-03-13 Mokwalo Pharma S.A. Compositions comprising strontium and vitamin d and uses thereof
FR2875807B1 (fr) 2004-09-30 2006-11-17 Servier Lab Forme cristalline alpha du ranelate de strontium, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
DE14172390T1 (de) 2004-10-08 2014-12-31 Forward Pharma A/S Gesteuerte Freisetzung von pharmazeutischen Zusammensetzungen mit Fumarinsäureester
US20080004344A1 (en) * 2004-11-10 2008-01-03 Aditech Pharma Ab Novel Salts of Fumaric Acid Monoalkylesters and Their Pharmaceutical Use
FR2899895B1 (fr) * 2006-04-12 2010-09-17 Servier Lab Nouveaux sels de strontium d'acides sulfoniques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ATE499120T1 (de) 2006-05-26 2011-03-15 Baxter Int Injizierbare fibrin-zusammensetzung zur knochenverstärkung
GB0612028D0 (en) * 2006-06-16 2006-07-26 Imp Innovations Ltd Bioactive glass
US20070292535A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating arthritic and or osteoporitic conditions
US20070292529A1 (en) * 2006-06-19 2007-12-20 Tabbiner Philip S Strontium compositions and methods of treating osteoporotic conditions
CN101204375B (zh) * 2006-12-19 2010-09-29 北京德众万全药物技术开发有限公司 一种雷奈酸锶干混悬剂
MX2009011268A (es) * 2007-04-23 2009-11-02 Baxter Int Composiciones de fibrina que contienen compuestos de estroncio.
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US8642831B2 (en) 2008-02-29 2014-02-04 Ferrosan Medical Devices A/S Device for promotion of hemostasis and/or wound healing
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US8906420B2 (en) 2009-01-09 2014-12-09 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
GB0911365D0 (en) 2009-06-30 2009-08-12 Bioceramic Therapeutics Ltd Multicomponent glasses for use as coatings and in personal care products
FR2953139B1 (fr) 2009-11-27 2012-04-13 Servier Lab Composition pharmaceutique comprenant un sel de strontium, de la vitamine d et une cyclodextrine
WO2011110597A1 (de) 2010-03-11 2011-09-15 Azad Pharmaceutical Ingredients Ag Verfahren zur herstellung von strontiumranelat
SA111320355B1 (ar) 2010-04-07 2015-01-08 Baxter Heathcare S A إسفنجة لايقاف النزف
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EP2530068A1 (en) 2011-05-31 2012-12-05 Lacer, S.A. New strontium salts, synthesis and use thereof in the treatment of osteoporosis
KR102102002B1 (ko) 2011-10-11 2020-04-20 백스터 인터내셔널 인코포레이티드 지혈 조성물
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JP6489485B2 (ja) 2013-12-11 2019-03-27 フェロサン メディカル デバイシーズ エイ/エス 押し出し増強因子を含んでいる乾燥組成物
CN106999621B (zh) 2014-10-13 2020-07-03 弗罗桑医疗设备公司 用于止血和伤口愈合的干组合物
BR112017013565B1 (pt) 2014-12-24 2021-12-28 Ferrosan Medical Devices A/S Seringa para retenção e mistura de primeira e segunda substâncias
CN107771093B (zh) 2015-07-03 2021-06-15 弗罗桑医疗设备公司 用于混合两种组分和用于在存储条件下保持真空的注射器
US10463636B2 (en) 2016-09-30 2019-11-05 Deanna J. Nelson Pharmaceutical quality strontium L-lactate
JP7395113B2 (ja) 2018-05-09 2023-12-11 フェロサン メディカル デバイシーズ エイ/エス 止血組成物を調製する方法

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Also Published As

Publication number Publication date
DE69719408D1 (de) 2003-04-10
FR2749759A1 (fr) 1997-12-19
JP3935557B2 (ja) 2007-06-27
ZA975323B (en) 1998-01-14
CA2206837A1 (fr) 1997-12-17
CN1136856C (zh) 2004-02-04
ES2193337T3 (es) 2003-11-01
DK0813869T3 (da) 2003-06-02
EP0813869B1 (fr) 2003-03-05
DE69719408T2 (de) 2003-12-24
NO972764D0 (no) 1997-06-16
BR9703603A (pt) 1998-09-01
AU2490297A (en) 1998-01-08
HU227935B1 (en) 2012-06-28
AU711950B2 (en) 1999-10-28
ATE233558T1 (de) 2003-03-15
NO972764L (no) 1997-12-18
CA2206837C (fr) 2002-12-03
HUP9701059A2 (hu) 1998-03-02
NZ328106A (en) 2001-04-27
CN1179944A (zh) 1998-04-29
FR2749759B1 (fr) 1999-11-26
JPH1059852A (ja) 1998-03-03
HU9701059D0 (en) 1997-08-28
US5856356A (en) 1999-01-05
EP0813869A1 (fr) 1997-12-29
HUP9701059A3 (en) 1998-05-28

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