NO315785B1 - Trifenyletylener til beskyttelse mot og behandling av osteoporose - Google Patents
Trifenyletylener til beskyttelse mot og behandling av osteoporose Download PDFInfo
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- NO315785B1 NO315785B1 NO19971037A NO971037A NO315785B1 NO 315785 B1 NO315785 B1 NO 315785B1 NO 19971037 A NO19971037 A NO 19971037A NO 971037 A NO971037 A NO 971037A NO 315785 B1 NO315785 B1 NO 315785B1
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- Prior art keywords
- estrogen
- compound
- compounds
- bone
- formula
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Materials For Photolithography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9418067A GB9418067D0 (en) | 1994-09-07 | 1994-09-07 | Triphenylethylenes for the prevention and treatment of osteoporosis |
| PCT/FI1995/000475 WO1996007402A1 (en) | 1994-09-07 | 1995-09-06 | Triphenylethylenes for the prevention and treatment of osteoporosis |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO971037D0 NO971037D0 (no) | 1997-03-06 |
| NO971037L NO971037L (no) | 1997-04-29 |
| NO315785B1 true NO315785B1 (no) | 2003-10-27 |
Family
ID=10761007
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19971037A NO315785B1 (no) | 1994-09-07 | 1997-03-06 | Trifenyletylener til beskyttelse mot og behandling av osteoporose |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US5750576A (el) |
| EP (1) | EP0779808B1 (el) |
| JP (1) | JP3910211B2 (el) |
| AT (1) | ATE183389T1 (el) |
| CA (1) | CA2198389C (el) |
| DE (1) | DE69511566T2 (el) |
| DK (1) | DK0779808T3 (el) |
| ES (1) | ES2135083T3 (el) |
| FI (1) | FI118755B (el) |
| GB (1) | GB9418067D0 (el) |
| GR (1) | GR3031109T3 (el) |
| IL (1) | IL115171A (el) |
| NO (1) | NO315785B1 (el) |
| NZ (1) | NZ291836A (el) |
| SI (1) | SI0779808T1 (el) |
| WO (1) | WO1996007402A1 (el) |
| ZA (1) | ZA957481B (el) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5504074A (en) * | 1993-08-06 | 1996-04-02 | Children's Medical Center Corporation | Estrogenic compounds as anti-angiogenic agents |
| GB9609171D0 (en) | 1996-05-02 | 1996-07-03 | Orion Yhtymae Oy | Antioxidant compounds |
| WO1998046588A2 (en) * | 1997-04-11 | 1998-10-22 | Neorx Corporation | Compounds and therapies for the prevention of vascular and non-vascular pathologies |
| GB9803521D0 (en) * | 1998-02-19 | 1998-04-15 | Orion Yhtymo Oy | New compounds and pharmaceutical compositions thereof |
| US20040186185A1 (en) * | 1998-05-07 | 2004-09-23 | Steiner Mitchell S. | Method for treatment and chemoprevention of prostate cancer |
| US7005428B1 (en) | 1998-06-11 | 2006-02-28 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| US6465445B1 (en) | 1998-06-11 | 2002-10-15 | Endorecherche, Inc. | Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors |
| TW593256B (en) * | 1999-11-16 | 2004-06-21 | Hormos Medical Oy Ltd | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
| SI1235776T1 (sl) * | 1999-11-16 | 2006-06-30 | Hormos Medical Corp | Trifenilalkenski derivati in njihova uporaba kot selektivni estrogenski receptorski modulatorji |
| US6245819B1 (en) * | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
| US20080249183A1 (en) * | 2001-11-29 | 2008-10-09 | Steiner Mitchell S | Treatment of androgen-deprivation induced osteoporosis |
| US20050080143A1 (en) * | 2001-11-29 | 2005-04-14 | Steiner Mitchell S. | Treatment of androgen-deprivation induced osteoporosis |
| US20040214898A1 (en) * | 2001-11-29 | 2004-10-28 | Steiner Mitchell S. | Methods for treating hot flashes |
| US20060269611A1 (en) * | 2001-11-29 | 2006-11-30 | Steiner Mitchell S | Prevention and treatment of androgen-deprivation induced osteoporosis |
| US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
| US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
| US8642079B2 (en) | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
| US20050187302A1 (en) * | 2004-02-23 | 2005-08-25 | Hormos Medical Corporation | Method for treatment or prevention of osteoporosis in individuals with high bone turnover |
| ES2392344T3 (es) | 2004-05-04 | 2012-12-07 | Hormos Medical Ltd. | Formulaciones orales líquidas de ospemifeno |
| US8758821B2 (en) | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
| US20060293294A1 (en) * | 2004-09-03 | 2006-12-28 | Hormos Medical Corporation | Method for treatment or prevention of androgen deficiency |
| US20060270641A1 (en) * | 2005-05-31 | 2006-11-30 | Steiner Mitchell S | Method for chemoprevention of prostate cancer |
| US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US8158828B2 (en) | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
| US8637706B2 (en) | 2005-11-28 | 2014-01-28 | Gtx, Inc. | Nuclear receptor binding agents |
| US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| CN101448490A (zh) * | 2006-05-22 | 2009-06-03 | 霍尔莫斯医疗有限公司 | 治疗慢性非细菌性前列腺炎的选择性雌激素受体调节剂或者芳香酶抑制剂 |
| US20080176255A1 (en) * | 2007-01-23 | 2008-07-24 | Edward Sobek | Mold detection composition and methods |
| EP2121553B1 (en) | 2007-02-14 | 2012-06-27 | Hormos Medical Ltd. | Method for the preparation of therapeutically valuable triphenylbutene derivatives |
| US7504530B2 (en) | 2007-02-14 | 2009-03-17 | Hormos Medical Ltd. | Methods for the preparation of fispemifene from ospemifene |
| US20080312239A1 (en) * | 2007-06-13 | 2008-12-18 | Quatrx Pharmaceuticals Company | Methods for the treatment of erectile dysfunction using fispemifene |
| US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| KR101149529B1 (ko) | 2009-09-11 | 2012-05-25 | 한국화학연구원 | 인덴온 유도체 및 이를 포함하는 약학적 조성물 |
| CN102770402B (zh) | 2010-01-19 | 2016-01-20 | 坎布雷卡尔斯库加公司 | 制造二苯甲酮衍生物的新方法 |
| JP6174156B2 (ja) * | 2012-10-19 | 2017-08-02 | フェルミオン オサケ ユキチュア | オスペミフェンの製造方法 |
| US20150321983A1 (en) | 2012-10-19 | 2015-11-12 | Fermion Oy | A process for the preparation of ospemifene |
| CN103739456A (zh) * | 2013-12-03 | 2014-04-23 | 镇江圣安医药有限公司 | 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用 |
| JP6697467B2 (ja) | 2014-12-29 | 2020-05-20 | オロン エス．ピー．エー． | オスペミフェン及びフィスペミフェンを調製するためのプロセス |
| WO2016110805A1 (en) * | 2015-01-09 | 2016-07-14 | Glenmark Pharmaceuticals Limited | Process for preparation of ospemifene |
| RU2694832C2 (ru) | 2015-03-10 | 2019-07-17 | Шионоги Инк. | Твёрдые дисперсии |
| KR102052133B1 (ko) * | 2017-08-10 | 2019-12-05 | 고려대학교 산학협력단 | 당 부가된 오스페미펜, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물 |
| GR1009542B (el) | 2018-04-25 | 2019-06-07 | Φαρματεν Α.Β.Ε.Ε. | Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων |
| KR20220115062A (ko) | 2021-02-09 | 2022-08-17 | (주)오스티오뉴로젠 | 크로몬 구조의 화합물을 포함하는 골다공증의 예방 및 치료용 약학적 조성물 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
-
1994
- 1994-09-07 GB GB9418067A patent/GB9418067D0/en active Pending
-
1995
- 1995-09-05 IL IL11517195A patent/IL115171A/xx not_active IP Right Cessation
- 1995-09-06 EP EP95929903A patent/EP0779808B1/en not_active Expired - Lifetime
- 1995-09-06 CA CA002198389A patent/CA2198389C/en not_active Expired - Lifetime
- 1995-09-06 AT AT95929903T patent/ATE183389T1/de active
- 1995-09-06 JP JP50923496A patent/JP3910211B2/ja not_active Expired - Lifetime
- 1995-09-06 ES ES95929903T patent/ES2135083T3/es not_active Expired - Lifetime
- 1995-09-06 SI SI9530295T patent/SI0779808T1/xx unknown
- 1995-09-06 DK DK95929903T patent/DK0779808T3/da active
- 1995-09-06 NZ NZ291836A patent/NZ291836A/en not_active IP Right Cessation
- 1995-09-06 ZA ZA957481A patent/ZA957481B/xx unknown
- 1995-09-06 WO PCT/FI1995/000475 patent/WO1996007402A1/en active IP Right Grant
- 1995-09-06 DE DE69511566T patent/DE69511566T2/de not_active Expired - Lifetime
- 1995-09-06 US US08/793,938 patent/US5750576A/en not_active Expired - Lifetime
-
1997
- 1997-03-04 FI FI970920A patent/FI118755B/fi not_active IP Right Cessation
- 1997-03-06 NO NO19971037A patent/NO315785B1/no not_active IP Right Cessation
- 1997-09-25 US US08/937,887 patent/US5912273A/en not_active Expired - Lifetime
-
1999
- 1999-08-30 GR GR990402191T patent/GR3031109T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2135083T3 (es) | 1999-10-16 |
| WO1996007402A1 (en) | 1996-03-14 |
| EP0779808A1 (en) | 1997-06-25 |
| IL115171A0 (en) | 1995-12-31 |
| DE69511566T2 (de) | 2000-04-27 |
| FI970920A (fi) | 1997-03-04 |
| CA2198389C (en) | 2007-02-20 |
| US5912273A (en) | 1999-06-15 |
| ZA957481B (en) | 1996-04-09 |
| DE69511566D1 (de) | 1999-09-23 |
| CA2198389A1 (en) | 1996-03-14 |
| EP0779808B1 (en) | 1999-08-18 |
| US5750576A (en) | 1998-05-12 |
| DK0779808T3 (da) | 2000-03-13 |
| AU3347895A (en) | 1996-03-27 |
| JP3910211B2 (ja) | 2007-04-25 |
| JPH10505079A (ja) | 1998-05-19 |
| GB9418067D0 (en) | 1994-10-26 |
| FI970920A0 (fi) | 1997-03-04 |
| FI118755B (fi) | 2008-03-14 |
| GR3031109T3 (en) | 1999-12-31 |
| ATE183389T1 (de) | 1999-09-15 |
| IL115171A (en) | 2001-08-26 |
| NZ291836A (en) | 1998-06-26 |
| NO971037D0 (no) | 1997-03-06 |
| NO971037L (no) | 1997-04-29 |
| SI0779808T1 (en) | 1999-10-31 |
| AU699845B2 (en) | 1998-12-17 |
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Legal Events
| Date | Code | Title | Description |
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| MK1K | Patent expired |