FI970920A - Trifenyylietyleenejä käytettäväksi osteoporoosin ehkäisyyn ja hoitoon - Google Patents

Trifenyylietyleenejä käytettäväksi osteoporoosin ehkäisyyn ja hoitoon Download PDF

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Publication number
FI970920A
FI970920A FI970920A FI970920A FI970920A FI 970920 A FI970920 A FI 970920A FI 970920 A FI970920 A FI 970920A FI 970920 A FI970920 A FI 970920A FI 970920 A FI970920 A FI 970920A
Authority
FI
Finland
Prior art keywords
pct
osteoporosis
prevention
treatment
triphenylethylenes
Prior art date
Application number
FI970920A
Other languages
English (en)
Swedish (sv)
Other versions
FI970920A0 (fi
FI118755B (fi
Inventor
Michael Degregorio
Lauri Veikko Matti Kangas
Pirkko Haerkoenen
Kalervo Vaeaenaenen
Aire Laine
Valerie Wiebe
Original Assignee
Orion Yhtymae Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orion Yhtymae Oy filed Critical Orion Yhtymae Oy
Publication of FI970920A0 publication Critical patent/FI970920A0/fi
Publication of FI970920A publication Critical patent/FI970920A/fi
Application granted granted Critical
Publication of FI118755B publication Critical patent/FI118755B/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Photolithography (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
FI970920A 1994-09-07 1997-03-04 Trifenyylietyleenejä käytettäväksi osteoporoosin ehkäisyyn ja hoitoon FI118755B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9418067 1994-09-07
GB9418067A GB9418067D0 (en) 1994-09-07 1994-09-07 Triphenylethylenes for the prevention and treatment of osteoporosis
PCT/FI1995/000475 WO1996007402A1 (en) 1994-09-07 1995-09-06 Triphenylethylenes for the prevention and treatment of osteoporosis
FI9500475 1995-09-06

Publications (3)

Publication Number Publication Date
FI970920A0 FI970920A0 (fi) 1997-03-04
FI970920A true FI970920A (fi) 1997-03-04
FI118755B FI118755B (fi) 2008-03-14

Family

ID=10761007

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970920A FI118755B (fi) 1994-09-07 1997-03-04 Trifenyylietyleenejä käytettäväksi osteoporoosin ehkäisyyn ja hoitoon

Country Status (17)

Country Link
US (2) US5750576A (fi)
EP (1) EP0779808B1 (fi)
JP (1) JP3910211B2 (fi)
AT (1) ATE183389T1 (fi)
CA (1) CA2198389C (fi)
DE (1) DE69511566T2 (fi)
DK (1) DK0779808T3 (fi)
ES (1) ES2135083T3 (fi)
FI (1) FI118755B (fi)
GB (1) GB9418067D0 (fi)
GR (1) GR3031109T3 (fi)
IL (1) IL115171A (fi)
NO (1) NO315785B1 (fi)
NZ (1) NZ291836A (fi)
SI (1) SI0779808T1 (fi)
WO (1) WO1996007402A1 (fi)
ZA (1) ZA957481B (fi)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504074A (en) * 1993-08-06 1996-04-02 Children's Medical Center Corporation Estrogenic compounds as anti-angiogenic agents
GB9609171D0 (en) 1996-05-02 1996-07-03 Orion Yhtymae Oy Antioxidant compounds
AU6959898A (en) * 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
GB9803521D0 (en) 1998-02-19 1998-04-15 Orion Yhtymo Oy New compounds and pharmaceutical compositions thereof
US20040186185A1 (en) * 1998-05-07 2004-09-23 Steiner Mitchell S. Method for treatment and chemoprevention of prostate cancer
US7005428B1 (en) 1998-06-11 2006-02-28 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
US6465445B1 (en) 1998-06-11 2002-10-15 Endorecherche, Inc. Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors
SI1235776T1 (sl) * 1999-11-16 2006-06-30 Hormos Medical Corp Trifenilalkenski derivati in njihova uporaba kot selektivni estrogenski receptorski modulatorji
TW593256B (en) * 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
US20080249183A1 (en) * 2001-11-29 2008-10-09 Steiner Mitchell S Treatment of androgen-deprivation induced osteoporosis
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US20040214898A1 (en) * 2001-11-29 2004-10-28 Steiner Mitchell S. Methods for treating hot flashes
US20050080143A1 (en) * 2001-11-29 2005-04-14 Steiner Mitchell S. Treatment of androgen-deprivation induced osteoporosis
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US20050187302A1 (en) * 2004-02-23 2005-08-25 Hormos Medical Corporation Method for treatment or prevention of osteoporosis in individuals with high bone turnover
US8758821B2 (en) 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
CA2565134C (en) * 2004-05-04 2013-05-21 Veli-Matti Lehtola Novel oral formulations of ospemifene
US20060293294A1 (en) * 2004-09-03 2006-12-28 Hormos Medical Corporation Method for treatment or prevention of androgen deficiency
US20060270641A1 (en) * 2005-05-31 2006-11-30 Steiner Mitchell S Method for chemoprevention of prostate cancer
US8158828B2 (en) 2005-11-28 2012-04-17 Gtx, Inc. Nuclear receptor binding agents
US8546451B2 (en) 2005-11-28 2013-10-01 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US8637706B2 (en) 2005-11-28 2014-01-28 Gtx, Inc. Nuclear receptor binding agents
US9409856B2 (en) 2005-11-28 2016-08-09 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
EP2029128B1 (en) * 2006-05-22 2015-08-05 Hormos Medical Ltd. Method of treatment of chronic nonbacterial prostatitis with selective estrogen receptor modulators or aromatase inhibitors
US20080176255A1 (en) * 2007-01-23 2008-07-24 Edward Sobek Mold detection composition and methods
MX2009008660A (es) 2007-02-14 2009-10-13 Hormos Medical Ltd Metodo para la preparacion de derivados de trifenilbuteno terapeuticamente valiosos.
WO2008099060A2 (en) * 2007-02-14 2008-08-21 Hormos Medical Ltd Methods for the preparation of fispemifene from ospemifene
WO2008157335A2 (en) 2007-06-13 2008-12-24 Quatrx Pharmaceuticals Company Methods for the treatment of erectile dysfunction using fispemifene
US9624161B2 (en) 2009-02-23 2017-04-18 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
US9427418B2 (en) 2009-02-23 2016-08-30 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
KR101149529B1 (ko) 2009-09-11 2012-05-25 한국화학연구원 인덴온 유도체 및 이를 포함하는 약학적 조성물
DK2526080T3 (da) * 2010-01-19 2014-04-28 Cambrex Karlskoga Ab Nye fremgangsmåder til fremstilling af benzophenonderivater
US20150321983A1 (en) 2012-10-19 2015-11-12 Fermion Oy A process for the preparation of ospemifene
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
CN103739456A (zh) * 2013-12-03 2014-04-23 镇江圣安医药有限公司 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用
ES2717546T3 (es) 2014-12-29 2019-06-21 Olon Spa Proceso para la preparación de ospemifeno y fispemifeno
WO2016110805A1 (en) * 2015-01-09 2016-07-14 Glenmark Pharmaceuticals Limited Process for preparation of ospemifene
AU2016229086B2 (en) 2015-03-10 2018-12-06 Shionogi Inc. Solid dispersions
KR102052133B1 (ko) * 2017-08-10 2019-12-05 고려대학교 산학협력단 당 부가된 오스페미펜, 이의 제조방법 및 이를 유효성분으로 함유하는 약학적 조성물
GR1009542B (el) 2018-04-25 2019-06-07 Φαρματεν Α.Β.Ε.Ε. Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων
KR20220115062A (ko) 2021-02-09 2022-08-17 (주)오스티오뉴로젠 크로몬 구조의 화합물을 포함하는 골다공증의 예방 및 치료용 약학적 조성물

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9207437D0 (en) * 1992-04-03 1992-05-20 Orion Yhtymae Oy Topical administration of toremifene and its metabolites

Also Published As

Publication number Publication date
ZA957481B (en) 1996-04-09
JP3910211B2 (ja) 2007-04-25
DE69511566T2 (de) 2000-04-27
NZ291836A (en) 1998-06-26
JPH10505079A (ja) 1998-05-19
AU699845B2 (en) 1998-12-17
IL115171A0 (en) 1995-12-31
US5912273A (en) 1999-06-15
WO1996007402A1 (en) 1996-03-14
ES2135083T3 (es) 1999-10-16
AU3347895A (en) 1996-03-27
FI970920A0 (fi) 1997-03-04
NO315785B1 (no) 2003-10-27
GR3031109T3 (en) 1999-12-31
EP0779808B1 (en) 1999-08-18
NO971037D0 (no) 1997-03-06
FI118755B (fi) 2008-03-14
CA2198389C (en) 2007-02-20
NO971037L (no) 1997-04-29
DE69511566D1 (de) 1999-09-23
EP0779808A1 (en) 1997-06-25
SI0779808T1 (en) 1999-10-31
CA2198389A1 (en) 1996-03-14
IL115171A (en) 2001-08-26
ATE183389T1 (de) 1999-09-15
US5750576A (en) 1998-05-12
GB9418067D0 (en) 1994-10-26
DK0779808T3 (da) 2000-03-13

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