NO315406B1 - Blanding som omfatter lamell¶re polymeriske partikler samt fremstilling derav - Google Patents

Blanding som omfatter lamell¶re polymeriske partikler samt fremstilling derav Download PDF

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Publication number
NO315406B1
NO315406B1 NO19976018A NO976018A NO315406B1 NO 315406 B1 NO315406 B1 NO 315406B1 NO 19976018 A NO19976018 A NO 19976018A NO 976018 A NO976018 A NO 976018A NO 315406 B1 NO315406 B1 NO 315406B1
Authority
NO
Norway
Prior art keywords
polymer
particles
active agent
mixture according
lamellar
Prior art date
Application number
NO19976018A
Other languages
English (en)
Norwegian (no)
Other versions
NO976018D0 (no
NO976018L (no
Inventor
Allan G A Coombes
Stanley Stewart Davis
Diane L Major
John M Wood
Original Assignee
West Pharmaceutical Service Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by West Pharmaceutical Service Dr filed Critical West Pharmaceutical Service Dr
Publication of NO976018D0 publication Critical patent/NO976018D0/no
Publication of NO976018L publication Critical patent/NO976018L/no
Publication of NO315406B1 publication Critical patent/NO315406B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/788Of specified organic or carbon-based composition
    • Y10S977/795Composed of biological material
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/84Manufacture, treatment, or detection of nanostructure
    • Y10S977/895Manufacture, treatment, or detection of nanostructure having step or means utilizing chemical property
    • Y10S977/896Chemical synthesis, e.g. chemical bonding or breaking
    • Y10S977/897Polymerization
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915Therapeutic or pharmaceutical composition
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/915Therapeutic or pharmaceutical composition
    • Y10S977/917Vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Materials For Medical Uses (AREA)
  • Graft Or Block Polymers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
NO19976018A 1995-07-13 1997-12-22 Blanding som omfatter lamell¶re polymeriske partikler samt fremstilling derav NO315406B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9514285.7A GB9514285D0 (en) 1995-07-13 1995-07-13 Polymeric lamellar substrate particles for drug delivery
PCT/GB1996/001695 WO1997002810A2 (en) 1995-07-13 1996-07-15 Polymeric lamellar substrate particles for drug delivery

Publications (3)

Publication Number Publication Date
NO976018D0 NO976018D0 (no) 1997-12-22
NO976018L NO976018L (no) 1997-12-22
NO315406B1 true NO315406B1 (no) 2003-09-01

Family

ID=10777561

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19976018A NO315406B1 (no) 1995-07-13 1997-12-22 Blanding som omfatter lamell¶re polymeriske partikler samt fremstilling derav

Country Status (13)

Country Link
US (1) US6001395A (da)
EP (1) EP0837673B1 (da)
JP (1) JPH11508912A (da)
AT (1) ATE214918T1 (da)
AU (1) AU709031B2 (da)
CA (1) CA2223884A1 (da)
DE (1) DE69620182T2 (da)
DK (1) DK0837673T3 (da)
ES (1) ES2175109T3 (da)
GB (1) GB9514285D0 (da)
NO (1) NO315406B1 (da)
PT (1) PT837673E (da)
WO (1) WO1997002810A2 (da)

Families Citing this family (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884435B1 (en) 1997-01-30 2005-04-26 Chiron Corporation Microparticles with adsorbent surfaces, methods of making same, and uses thereof
EP1275380A1 (en) * 1997-01-30 2003-01-15 Chiron Corporation Use of microparticles with adsorbed antigen to stimulate immune responses
WO1998033487A1 (en) * 1997-01-30 1998-08-06 Chiron Corporation Use of microparticles with adsorbed antigen to stimulate immune responses
US7135191B2 (en) * 1997-09-04 2006-11-14 Zsolt Istvan Hertelendy Urogenital or anorectal transmucosal vaccine delivery system
GB9722682D0 (en) * 1997-10-27 1997-12-24 Scherer Ltd R P Pharmaceutical products
US20030059471A1 (en) * 1997-12-15 2003-03-27 Compton Bruce Jon Oral delivery formulation
US7393630B2 (en) 1997-12-16 2008-07-01 Novartis Vaccines And Diagnostics, Inc. Use of microparticles combined with submicron oil-in-water emulsions
EP1042001B1 (en) 1997-12-16 2002-04-03 Chiron Corporation Use of microparticles combined with submicron oil-in-water emulsions
SE9801288D0 (sv) * 1998-04-14 1998-04-14 Astra Ab Vaccine delivery system and metod of production
ES2260923T3 (es) * 1998-07-29 2006-11-01 Chiron Corporation Micorparticulas con superficies adsorbentes, procedimientos de fabricacion y uso de las mismas.
ATE295151T1 (de) 1998-10-01 2005-05-15 Powderject Res Ltd Sprühbeschichtete mikropartikel für nadellose spritzen
FR2786098B1 (fr) 1998-11-20 2003-05-30 Flamel Tech Sa Particules a base de polyaminoacide(s) et susceptibles d'etre utilisees comme vecteurs de principe(s) actif(s), suspension colloidale les comprenant et leurs procedes de fabrication
US6365173B1 (en) 1999-01-14 2002-04-02 Efrat Biopolymers Ltd. Stereocomplex polymeric carriers for drug delivery
WO2000050050A1 (en) * 1999-02-23 2000-08-31 Isis Pharmaceuticals, Inc. Multiparticulate formulation
US8206749B1 (en) 1999-02-26 2012-06-26 Novartis Vaccines And Diagnostics, Inc. Microemulsions with adsorbed macromolecules and microparticles
GB9905136D0 (en) 1999-03-06 1999-04-28 Danbiosyst Uk Surface modification of lamellar particles
US20050214227A1 (en) * 1999-03-08 2005-09-29 Powderject Research Limited Microparticle formulations for sustained-release of bioactive compounds
US7713739B1 (en) 2000-11-17 2010-05-11 Novartis Vaccines And Diagnostics, Inc. Microparticle-based transfection and activation of dendritic cells
FR2801226B1 (fr) 1999-11-23 2002-01-25 Flamel Tech Sa Suspension colloidale de particules submicroniques de vectorisation de principes actifs et son mode de preparation
FR2814952B1 (fr) 2000-10-06 2004-01-02 Flamel Tech Sa Suspension colloidale de particules submicromiques de vectorisation de principes actifs et leur mode de preparation
AU2001290678A1 (en) * 2000-09-08 2002-03-22 Powderject Research Limited Alginate particle formulation
ATE350015T1 (de) 2000-09-28 2007-01-15 Novartis Vaccines & Diagnostic Mikropartikelzusammensetzungen und verfahren zu ihrer herstellung
US7266687B2 (en) * 2001-02-16 2007-09-04 Motorola, Inc. Method and apparatus for storing and distributing encryption keys
CA2476626A1 (en) * 2002-02-20 2003-08-28 Chiron Corporation Microparticles with adsorbed polypeptide-containing molecules
CA2480826C (fr) 2002-04-09 2012-02-07 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
US7285289B2 (en) * 2002-04-12 2007-10-23 Nagy Jon O Nanoparticle vaccines
JP2003342196A (ja) * 2002-05-31 2003-12-03 Mukku:Kk 静脈注射用組成物、その製造法およびその製剤
FR2840614B1 (fr) 2002-06-07 2004-08-27 Flamel Tech Sa Polyaminoacides fonctionnalises par de l'alpha-tocopherol et leurs applications notamment therapeutiques
US7649023B2 (en) 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
JP2006525354A (ja) * 2003-05-01 2006-11-09 アルキメデス・ディヴェロップメント・リミテッド Lh−rhアナログロイプロイドの経鼻投与
ES2596553T3 (es) 2003-06-02 2017-01-10 Glaxosmithkline Biologicals Sa Composiciones inmunogénicas a base de micropartículas que comprenden toxoide adsorbido y un antígeno que contiene un polisacárido
FR2859909B1 (fr) 2003-09-22 2007-09-07 Biomerieux Sa Procede de preparation de microparticules bioresorbables, microparticules obtenues et utilisation
US20060263350A1 (en) * 2003-09-26 2006-11-23 Fairfield Clinical Trials Llc Combination antihistamine medication
CA2564588A1 (en) * 2004-05-12 2005-12-01 Surmodics, Inc. Natural biodegradable polysaccharide coatings for medical articles
WO2007040557A1 (en) * 2005-09-21 2007-04-12 Surmodics, Inc. Coatings and articles including natural biodegradable polysaccharides
US20070071792A1 (en) * 2005-09-21 2007-03-29 Varner Signe E In VIVO formed matrices including natural biodegradale polysaccharides and ophthalmic uses thereof
WO2008051245A2 (en) 2005-12-02 2008-05-02 Novartis Ag Nanoparticles for use in immunogenic compositions
US8460362B2 (en) * 2006-07-20 2013-06-11 Orbusneich Medical, Inc. Bioabsorbable polymeric medical device
CN103494661B (zh) * 2006-07-20 2016-03-30 奥巴斯尼茨医学公司 可生物吸收的聚合物医疗器械
CN103122132B (zh) 2006-07-20 2016-03-16 奥巴斯尼茨医学公司 用于医疗器械的可生物吸收聚合物组合物
EP2073754A4 (en) * 2006-10-20 2012-09-26 Orbusneich Medical Inc BIOABSORBABLE POLYMER COMPOSITION AND MEDICAL DEVICE BACKGROUND
US7959942B2 (en) * 2006-10-20 2011-06-14 Orbusneich Medical, Inc. Bioabsorbable medical device with coating
WO2008070118A1 (en) * 2006-12-05 2008-06-12 Landec Corporation Drug delivery
US20090263346A1 (en) * 2006-12-05 2009-10-22 David Taft Systems and methods for delivery of drugs
US20100004124A1 (en) * 2006-12-05 2010-01-07 David Taft Systems and methods for delivery of materials for agriculture and aquaculture
US20090246155A1 (en) * 2006-12-05 2009-10-01 Landec Corporation Compositions and methods for personal care
US8399007B2 (en) * 2006-12-05 2013-03-19 Landec Corporation Method for formulating a controlled-release pharmaceutical formulation
US20080154241A1 (en) * 2006-12-07 2008-06-26 Burkstrand Michael J Latent stabilization of bioactive agents releasable from implantable medical articles
US20110130822A1 (en) * 2007-07-20 2011-06-02 Orbusneich Medical, Inc. Bioabsorbable Polymeric Compositions and Medical Devices
US20100094405A1 (en) * 2008-10-10 2010-04-15 Orbusneich Medical, Inc. Bioabsorbable Polymeric Medical Device
US8062739B2 (en) * 2007-08-31 2011-11-22 Zimmer, Inc. Hydrogels with gradient
US8114883B2 (en) * 2007-12-04 2012-02-14 Landec Corporation Polymer formulations for delivery of bioactive materials
ES2498091T3 (es) 2008-04-28 2014-09-24 Novartis Ag Procedimiento para producir nanopartículas
CA2723192A1 (en) 2008-05-07 2009-11-12 Surmodics, Inc. Delivery of nucleic acid complexes from particles
EP2349077A4 (en) * 2008-10-11 2015-01-21 Orbusneich Medical Inc BIORESORBABLE POLYMERIC COMPOSITIONS AND MEDICAL DEVICES
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
AU2014236938B2 (en) * 2013-03-14 2018-12-20 Allergan, Inc. Composition of a sustained-release delivery and method of stabilizing proteins during fabrication process
US11555177B2 (en) 2016-07-13 2023-01-17 President And Fellows Of Harvard College Antigen-presenting cell-mimetic scaffolds and methods for making and using the same

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4492720A (en) * 1983-11-15 1985-01-08 Benjamin Mosier Method of preparing microspheres for intravascular delivery
DK0724432T3 (da) * 1993-10-22 2003-01-27 Genentech Inc Fremgangsmåder og præparater til mikroindkapsling af antigener til brug som vacciner
GB9412273D0 (en) * 1994-06-18 1994-08-10 Univ Nottingham Administration means
US5827531A (en) * 1994-12-02 1998-10-27 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microcapsules and methods for making

Also Published As

Publication number Publication date
US6001395A (en) 1999-12-14
NO976018D0 (no) 1997-12-22
DE69620182D1 (de) 2002-05-02
WO1997002810A3 (en) 1997-02-20
ATE214918T1 (de) 2002-04-15
DK0837673T3 (da) 2002-07-22
EP0837673B1 (en) 2002-03-27
WO1997002810A2 (en) 1997-01-30
JPH11508912A (ja) 1999-08-03
PT837673E (pt) 2002-09-30
CA2223884A1 (en) 1997-01-30
EP0837673A2 (en) 1998-04-29
GB9514285D0 (en) 1995-09-13
ES2175109T3 (es) 2002-11-16
NO976018L (no) 1997-12-22
AU709031B2 (en) 1999-08-19
DE69620182T2 (de) 2003-01-16
AU6466596A (en) 1997-02-10

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