NO315373B1 - Spirosykliske metallprotease-inhibitorer - Google Patents
Spirosykliske metallprotease-inhibitorer Download PDFInfo
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- NO315373B1 NO315373B1 NO19990856A NO990856A NO315373B1 NO 315373 B1 NO315373 B1 NO 315373B1 NO 19990856 A NO19990856 A NO 19990856A NO 990856 A NO990856 A NO 990856A NO 315373 B1 NO315373 B1 NO 315373B1
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2476696P | 1996-08-28 | 1996-08-28 | |
| PCT/US1997/014557 WO1998008850A1 (en) | 1996-08-28 | 1997-08-22 | Spirocyclic metalloprotease inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO990856D0 NO990856D0 (no) | 1999-02-23 |
| NO990856L NO990856L (no) | 1999-04-28 |
| NO315373B1 true NO315373B1 (no) | 2003-08-25 |
Family
ID=21822299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19990856A NO315373B1 (no) | 1996-08-28 | 1999-02-23 | Spirosykliske metallprotease-inhibitorer |
Country Status (30)
| Country | Link |
|---|---|
| US (1) | US6015912A (es) |
| EP (1) | EP0927183B1 (es) |
| JP (2) | JP3495376B2 (es) |
| KR (1) | KR100326611B1 (es) |
| CN (1) | CN1105723C (es) |
| AR (1) | AR009358A1 (es) |
| AT (1) | ATE272062T1 (es) |
| AU (1) | AU736238B2 (es) |
| BR (1) | BR9713178A (es) |
| CA (1) | CA2264044A1 (es) |
| CO (1) | CO4900045A1 (es) |
| CZ (1) | CZ63799A3 (es) |
| DE (1) | DE69730033T2 (es) |
| DK (1) | DK0927183T3 (es) |
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| HK (1) | HK1021184A1 (es) |
| HU (1) | HUP9904694A3 (es) |
| ID (1) | ID19418A (es) |
| IL (1) | IL128667A (es) |
| NO (1) | NO315373B1 (es) |
| NZ (1) | NZ334257A (es) |
| PE (1) | PE107798A1 (es) |
| PL (1) | PL331920A1 (es) |
| PT (1) | PT927183E (es) |
| RU (1) | RU2203274C2 (es) |
| SK (1) | SK284041B6 (es) |
| TR (1) | TR199900429T2 (es) |
| TW (1) | TW581761B (es) |
| WO (1) | WO1998008850A1 (es) |
| ZA (1) | ZA977699B (es) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030206874A1 (en) * | 1996-11-21 | 2003-11-06 | The Proctor & Gamble Company | Promoting whole body health |
| HUP0004595A3 (en) | 1997-07-31 | 2001-12-28 | Procter & Gamble | Acyclic metalloprotease inhibitors |
| EP1918278A1 (en) | 1998-02-04 | 2008-05-07 | Novartis AG | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| US6410580B1 (en) | 1998-02-04 | 2002-06-25 | Novartis Ag | Sulfonylamino derivatives which inhibit matrix-degrading metalloproteinases |
| US6846478B1 (en) | 1998-02-27 | 2005-01-25 | The Procter & Gamble Company | Promoting whole body health |
| US6197974B1 (en) * | 1998-10-26 | 2001-03-06 | Abbott Laboratories | Enantioselective synthesis of 3-aminopyrrolidines |
| IL145089A0 (en) | 1999-03-03 | 2002-06-30 | Procter & Gamble | Alkenyl-and alkynyl-containing metalloprotease inhibitors |
| US6566381B1 (en) | 1999-03-03 | 2003-05-20 | The Procter & Gamble Company | Hetero-substituted metalloprotease inhibitors |
| DE60134855D1 (de) * | 2000-06-30 | 2008-08-28 | Procter & Gamble | Orale zubereitungen, die antimikrobielle wirkstoffe enthalten zur prävention von systemischen erkrankungen |
| CA2415065C (en) * | 2000-06-30 | 2009-09-15 | The Procter & Gamble Company | Oral compositions comprising host-response modulating agent |
| US8283135B2 (en) | 2000-06-30 | 2012-10-09 | The Procter & Gamble Company | Oral care compositions containing combinations of anti-bacterial and host-response modulating agents |
| FR2818643B1 (fr) * | 2000-12-22 | 2003-02-07 | Servier Lab | Nouveaux inhibiteurs de metalloproteases, leur procede de preparation et les compositions pharmaceutiques que les contiennent |
| WO2003016248A2 (en) | 2001-08-17 | 2003-02-27 | Bristol-Myers Squibb Company Patent Department | Bicyclic hydroxamates as inhibitors of matrix metalloproteinases and/or tnf-$g(a) converting enzyme (tace) |
| EP2617419A1 (en) | 2003-04-24 | 2013-07-24 | Incyte Corporation | Aza spiro alkane derivatives as inhibitors of metallproteases |
| DE102004004974A1 (de) * | 2004-01-31 | 2005-08-18 | Aventis Pharma Deutschland Gmbh | Thieno-Iminosäure-Derivate als Inhibitoren von Matrix-Metalloproteinasen |
| CN102417480B (zh) * | 2006-06-01 | 2015-08-26 | 塞诺菲-安万特股份有限公司 | 作为蛋白酶抑制剂的螺环腈类 |
| JP2010519329A (ja) * | 2007-02-27 | 2010-06-03 | バーテックス ファーマシューティカルズ インコーポレイテッド | セリンプロテアーゼ阻害剤 |
| KR101571654B1 (ko) * | 2007-02-28 | 2015-11-25 | 레오 파마 에이/에스 | 신규한 포스포디에스테라제 억제제 |
| NZ597982A (en) | 2009-09-04 | 2013-01-25 | Glaxosmithkline Llc | CHEMICAL COMPOUNDS for treating Hepatitis C virus |
| WO2012123298A1 (en) | 2011-03-11 | 2012-09-20 | F. Hoffmann-La Roche Ag | Antiviral compounds |
| RU2523284C9 (ru) * | 2012-05-31 | 2014-10-10 | Автономная Некоммерческая Организация "Научно-Исследовательский Центр Биотехнологии Антибиотиков И Других Биологически Активных Веществ "Биоан" | Способ модификации макролидного антибиотика олигомицина а с помощью реакции [3+2]-диполярного циклоприсоединения азида и алкинов. 33-дезокис-33-(триазол-1-ил)-олигомицины а и их биологическая активность |
| UA119247C2 (uk) | 2013-09-06 | 2019-05-27 | РОЙВЕНТ САЙЕНСИЗ ҐмбГ | Спіроциклічні сполуки як інгібітори триптофангідроксилази |
| US9611201B2 (en) | 2015-03-05 | 2017-04-04 | Karos Pharmaceuticals, Inc. | Processes for preparing (R)-1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanol and 1-(5-chloro-[1,1′-biphenyl]-2-yl)-2,2,2-trifluoroethanone |
| AR110150A1 (es) * | 2016-11-09 | 2019-02-27 | Roivant Sciences Gmbh | Procesos para la preparación de inhibidores de tph1 |
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| US4709046A (en) * | 1983-05-09 | 1987-11-24 | E. R. Squibb & Sons, Inc. | Acylmercaptoalkanoyl and mercaptoalkanoyl spiro compounds |
| EP0189370A3 (de) * | 1985-01-16 | 1988-01-27 | Sandoz Ag | Spiro-dioxolane, -dithiolane und -oxothiolane |
| GB8601368D0 (en) * | 1986-01-21 | 1986-02-26 | Ici America Inc | Hydroxamic acids |
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| US4847384A (en) * | 1987-03-12 | 1989-07-11 | Sandoz Pharm. Corp. | Process for the preparation of certain nitrogen-containing mono- and bicyclic ace inhibitors, and novel intermediates useful therefor |
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| DD298639A5 (de) * | 1989-12-21 | 1992-03-05 | Institut Fuer Chemische Technologie,De | Verfahren zur herstellung von sulfobetainsubstituierten alpha-sulfonyl-carbonsaeuren aus diallylammoniumsalzen |
| DE4011172A1 (de) * | 1990-04-06 | 1991-10-10 | Degussa | Verbindungen zur bekaempfung von pflanzenkrankheiten |
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| DE4127842A1 (de) * | 1991-08-22 | 1993-02-25 | Rhone Poulenc Rorer Gmbh | 5-((omega)-arylalky)-2-thienyl alkansaeuren, ihre salze und/oder ihre derivate |
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-
1997
- 1997-08-22 AU AU41532/97A patent/AU736238B2/en not_active Ceased
- 1997-08-22 IL IL12866797A patent/IL128667A/en not_active IP Right Cessation
- 1997-08-22 DE DE69730033T patent/DE69730033T2/de not_active Expired - Fee Related
- 1997-08-22 PL PL97331920A patent/PL331920A1/xx unknown
- 1997-08-22 AT AT97939445T patent/ATE272062T1/de not_active IP Right Cessation
- 1997-08-22 CZ CZ99637A patent/CZ63799A3/cs unknown
- 1997-08-22 CN CN97197542A patent/CN1105723C/zh not_active Expired - Fee Related
- 1997-08-22 HU HU9904694A patent/HUP9904694A3/hu unknown
- 1997-08-22 SK SK255-99A patent/SK284041B6/sk unknown
- 1997-08-22 ES ES97939445T patent/ES2225983T3/es not_active Expired - Lifetime
- 1997-08-22 DK DK97939445T patent/DK0927183T3/da active
- 1997-08-22 NZ NZ334257A patent/NZ334257A/xx unknown
- 1997-08-22 RU RU99106587/04A patent/RU2203274C2/ru not_active IP Right Cessation
- 1997-08-22 BR BR9713178-4A patent/BR9713178A/pt not_active IP Right Cessation
- 1997-08-22 PT PT97939445T patent/PT927183E/pt unknown
- 1997-08-22 TR TR1999/00429T patent/TR199900429T2/xx unknown
- 1997-08-22 WO PCT/US1997/014557 patent/WO1998008850A1/en not_active Application Discontinuation
- 1997-08-22 CA CA002264044A patent/CA2264044A1/en not_active Abandoned
- 1997-08-22 KR KR1019997001652A patent/KR100326611B1/ko not_active IP Right Cessation
- 1997-08-22 EP EP97939445A patent/EP0927183B1/en not_active Expired - Lifetime
- 1997-08-22 JP JP51171798A patent/JP3495376B2/ja not_active Expired - Fee Related
- 1997-08-26 US US08/918,328 patent/US6015912A/en not_active Expired - Fee Related
- 1997-08-27 AR ARP970103899A patent/AR009358A1/es unknown
- 1997-08-27 ZA ZA9707699A patent/ZA977699B/xx unknown
- 1997-08-27 CO CO97049506A patent/CO4900045A1/es unknown
- 1997-08-28 PE PE1997000769A patent/PE107798A1/es not_active Application Discontinuation
- 1997-08-28 ID IDP972995A patent/ID19418A/id unknown
-
1998
- 1998-02-03 TW TW087101299A patent/TW581761B/zh not_active IP Right Cessation
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1999
- 1999-02-23 NO NO19990856A patent/NO315373B1/no unknown
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2000
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2003
- 2003-08-13 JP JP2003292947A patent/JP2004002470A/ja not_active Withdrawn
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