NO314501B1 - Tetrahydronaftofuranaminforbindelser, fremgangsmåte ved fremstilling deravog farmasöytiske sammensetninger inneholdende dem - Google Patents
Tetrahydronaftofuranaminforbindelser, fremgangsmåte ved fremstilling deravog farmasöytiske sammensetninger inneholdende dem Download PDFInfo
- Publication number
- NO314501B1 NO314501B1 NO19964072A NO964072A NO314501B1 NO 314501 B1 NO314501 B1 NO 314501B1 NO 19964072 A NO19964072 A NO 19964072A NO 964072 A NO964072 A NO 964072A NO 314501 B1 NO314501 B1 NO 314501B1
- Authority
- NO
- Norway
- Prior art keywords
- ppm
- formula
- dihydrofuran
- propylamino
- tetrahydronaphtho
- Prior art date
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- 238000000034 method Methods 0.000 title claims description 17
- 239000008194 pharmaceutical composition Substances 0.000 title claims description 5
- 238000002360 preparation method Methods 0.000 title claims description 5
- -1 Tetrahydronaphthofuranamine Compounds Chemical class 0.000 title description 7
- 150000003839 salts Chemical class 0.000 claims abstract description 9
- 125000000217 alkyl group Chemical group 0.000 claims abstract description 8
- 125000000753 cycloalkyl group Chemical group 0.000 claims abstract description 4
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- 125000004432 carbon atom Chemical group C* 0.000 claims description 6
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- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229960000485 methotrexate Drugs 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 230000001095 motoneuron effect Effects 0.000 description 1
- AZTCBYBLWUXCCG-UHFFFAOYSA-N n-[4-(3-iodopropyl)phenyl]acetamide Chemical compound CC(=O)NC1=CC=C(CCCI)C=C1 AZTCBYBLWUXCCG-UHFFFAOYSA-N 0.000 description 1
- 101150006061 neur gene Proteins 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002547 new drug Substances 0.000 description 1
- 230000009871 nonspecific binding Effects 0.000 description 1
- 210000001672 ovary Anatomy 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 239000002244 precipitate Substances 0.000 description 1
- 150000003141 primary amines Chemical class 0.000 description 1
- 238000000425 proton nuclear magnetic resonance spectrum Methods 0.000 description 1
- 239000003368 psychostimulant agent Substances 0.000 description 1
- 239000002287 radioligand Substances 0.000 description 1
- 201000000980 schizophrenia Diseases 0.000 description 1
- 150000003335 secondary amines Chemical class 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910000029 sodium carbonate Inorganic materials 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000000527 sonication Methods 0.000 description 1
- 125000001424 substituent group Chemical group 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 239000003826 tablet Substances 0.000 description 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 239000012588 trypsin Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9511446A FR2739379B1 (fr) | 1995-09-29 | 1995-09-29 | Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO964072D0 NO964072D0 (no) | 1996-09-27 |
| NO964072L NO964072L (no) | 1997-04-01 |
| NO314501B1 true NO314501B1 (no) | 2003-03-31 |
Family
ID=9483043
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19964072A NO314501B1 (no) | 1995-09-29 | 1996-09-27 | Tetrahydronaftofuranaminforbindelser, fremgangsmåte ved fremstilling deravog farmasöytiske sammensetninger inneholdende dem |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5665765A (zh) |
| EP (1) | EP0765877B1 (zh) |
| JP (1) | JPH09110855A (zh) |
| CN (1) | CN1075067C (zh) |
| AT (1) | ATE256675T1 (zh) |
| AU (1) | AU707883B2 (zh) |
| CA (1) | CA2186337C (zh) |
| DE (1) | DE69631104T2 (zh) |
| DK (1) | DK0765877T3 (zh) |
| ES (1) | ES2213171T3 (zh) |
| FR (1) | FR2739379B1 (zh) |
| NO (1) | NO314501B1 (zh) |
| NZ (1) | NZ299465A (zh) |
| PT (1) | PT765877E (zh) |
| ZA (1) | ZA968167B (zh) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7216866B2 (en) * | 2003-04-28 | 2007-05-15 | Kyocera Mita Corporation | Sheet transport path switching mechanism |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4470990A (en) * | 1983-03-14 | 1984-09-11 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
| FR2613364B1 (fr) * | 1987-04-01 | 1989-06-09 | Adir | Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2613365B1 (fr) * | 1987-04-01 | 1989-07-28 | Adir | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
-
1995
- 1995-09-29 FR FR9511446A patent/FR2739379B1/fr not_active Expired - Fee Related
-
1996
- 1996-09-24 CA CA002186337A patent/CA2186337C/fr not_active Expired - Fee Related
- 1996-09-26 DE DE69631104T patent/DE69631104T2/de not_active Expired - Fee Related
- 1996-09-26 ES ES96402044T patent/ES2213171T3/es not_active Expired - Lifetime
- 1996-09-26 PT PT96402044T patent/PT765877E/pt unknown
- 1996-09-26 DK DK96402044T patent/DK0765877T3/da active
- 1996-09-26 AT AT96402044T patent/ATE256675T1/de not_active IP Right Cessation
- 1996-09-26 EP EP96402044A patent/EP0765877B1/fr not_active Expired - Lifetime
- 1996-09-27 AU AU65897/96A patent/AU707883B2/en not_active Ceased
- 1996-09-27 NO NO19964072A patent/NO314501B1/no not_active IP Right Cessation
- 1996-09-27 US US08/720,039 patent/US5665765A/en not_active Expired - Fee Related
- 1996-09-27 ZA ZA968167A patent/ZA968167B/xx unknown
- 1996-09-27 NZ NZ299465A patent/NZ299465A/en unknown
- 1996-09-27 CN CN96113084A patent/CN1075067C/zh not_active Expired - Fee Related
- 1996-09-30 JP JP8258217A patent/JPH09110855A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2186337A1 (fr) | 1997-03-30 |
| NO964072D0 (no) | 1996-09-27 |
| DE69631104D1 (de) | 2004-01-29 |
| NO964072L (no) | 1997-04-01 |
| ATE256675T1 (de) | 2004-01-15 |
| ES2213171T3 (es) | 2004-08-16 |
| PT765877E (pt) | 2004-04-30 |
| JPH09110855A (ja) | 1997-04-28 |
| EP0765877A1 (fr) | 1997-04-02 |
| DK0765877T3 (da) | 2004-04-19 |
| ZA968167B (en) | 1997-05-02 |
| EP0765877B1 (fr) | 2003-12-17 |
| CA2186337C (fr) | 2002-01-01 |
| NZ299465A (en) | 1997-06-24 |
| AU707883B2 (en) | 1999-07-22 |
| CN1075067C (zh) | 2001-11-21 |
| US5665765A (en) | 1997-09-09 |
| DE69631104T2 (de) | 2004-09-02 |
| FR2739379B1 (fr) | 1997-10-24 |
| FR2739379A1 (fr) | 1997-04-04 |
| AU6589796A (en) | 1997-04-10 |
| CN1150151A (zh) | 1997-05-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |