NO314080B1 - NMDA (N-metyl-D-aspartat) antagonister, farmasöytisk preparat inneholdendedisse og anvendelse derav for fremstilling av et medikament - Google Patents
NMDA (N-metyl-D-aspartat) antagonister, farmasöytisk preparat inneholdendedisse og anvendelse derav for fremstilling av et medikament Download PDFInfo
- Publication number
- NO314080B1 NO314080B1 NO19991533A NO991533A NO314080B1 NO 314080 B1 NO314080 B1 NO 314080B1 NO 19991533 A NO19991533 A NO 19991533A NO 991533 A NO991533 A NO 991533A NO 314080 B1 NO314080 B1 NO 314080B1
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- Norway
- Prior art keywords
- compound
- compound according
- dichloroindol
- acid
- propenoic acid
- Prior art date
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72317596A | 1996-09-30 | 1996-09-30 | |
| PCT/US1997/014486 WO1998014427A1 (en) | 1996-09-30 | 1997-08-18 | Nmda (n-methyl-d-aspartate) antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO991533D0 NO991533D0 (no) | 1999-03-29 |
| NO991533L NO991533L (no) | 1999-05-28 |
| NO314080B1 true NO314080B1 (no) | 2003-01-27 |
Family
ID=24905175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19991533A NO314080B1 (no) | 1996-09-30 | 1999-03-29 | NMDA (N-metyl-D-aspartat) antagonister, farmasöytisk preparat inneholdendedisse og anvendelse derav for fremstilling av et medikament |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0929521B1 (ko) |
| JP (1) | JP2001501221A (ko) |
| KR (1) | KR20000048715A (ko) |
| CN (1) | CN1139572C (ko) |
| AR (1) | AR009374A1 (ko) |
| AT (1) | ATE309215T1 (ko) |
| AU (1) | AU732997B2 (ko) |
| BR (1) | BR9712144A (ko) |
| CA (1) | CA2266556C (ko) |
| DE (1) | DE69734594T2 (ko) |
| DK (1) | DK0929521T3 (ko) |
| HU (1) | HUP0000882A3 (ko) |
| IL (1) | IL129187A0 (ko) |
| NO (1) | NO314080B1 (ko) |
| NZ (1) | NZ334343A (ko) |
| TW (1) | TW492958B (ko) |
| WO (1) | WO1998014427A1 (ko) |
| ZA (1) | ZA978602B (ko) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010053849A1 (en) * | 1999-06-16 | 2001-12-20 | Mary Jeanne Kreek | Plural biological sample arrays, and preparation and uses thereof |
| JP2004512260A (ja) | 2000-04-28 | 2004-04-22 | メモリアル スローン−ケッタリング キャンサー センター | 局所麻酔／オピオイド製剤およびその使用方法 |
| HU227197B1 (en) | 2000-10-24 | 2010-10-28 | Richter Gedeon Nyrt | Nmda receptor antagonist carboxylic acid amide derivatives and pharmaceutical compositions containing them |
| US7820688B2 (en) | 2001-04-27 | 2010-10-26 | Memorial Sloan-Kettering Cancer Center | Topical anesthetic/opioid formulations and uses thereof |
| US20030162825A1 (en) * | 2001-11-09 | 2003-08-28 | Sepracor Inc. | D-amino acid oxidase inhibitors for learning and memory |
| DE10306202A1 (de) * | 2003-02-13 | 2004-08-26 | Grünenthal GmbH | Arzneimittel enthaltend substituierte 2-Aryl-Aminoessigsäure-Verbindungen und/oder substituierte 2-Heteroaryl-Aminoessigsäure-Verbindungen |
| US7884124B2 (en) | 2006-06-30 | 2011-02-08 | Sepracor Inc. | Fluoro-substituted inhibitors of D-amino acid oxidase |
| EP2209765A4 (en) * | 2007-10-22 | 2010-12-01 | Orchid Res Lab Ltd | HISTONE DEACETYLASE INHIBITORS |
| EP2536713A1 (en) | 2010-02-16 | 2012-12-26 | Pfizer Inc. | (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors |
| EP3997092A4 (en) | 2019-07-08 | 2023-09-06 | University of Health Sciences & Pharmacy in St. Louis | G-PROTEIN POLARIZED OPIOID RECEPTOR AGONISTS/ANALGESICS WITH REDUCED ARRESTIN RECRUITMENT |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK0539503T3 (da) * | 1990-07-16 | 1996-05-13 | Merrell Pharma Inc | Excitatoriske aminosyreantagonister |
| GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
| WO1994027964A1 (en) * | 1993-05-27 | 1994-12-08 | Merrell Dow Pharmaceuticals Inc. | 3-(indol-3-yl) propenoic acid derivatives and as nmda antagonists |
| US5519048A (en) * | 1993-05-27 | 1996-05-21 | Merrell Pharmaceuticals Inc. | 3-(indol-3-yl)-propenoic acid derivatives and pharmaceutical compositions thereof |
| GB9319243D0 (en) * | 1993-09-17 | 1993-11-03 | Glaxo Spa | Heterocyclic compounds |
-
1997
- 1997-08-18 DK DK97938377T patent/DK0929521T3/da active
- 1997-08-18 EP EP97938377A patent/EP0929521B1/en not_active Expired - Lifetime
- 1997-08-18 WO PCT/US1997/014486 patent/WO1998014427A1/en active IP Right Grant
- 1997-08-18 KR KR1019990702680A patent/KR20000048715A/ko not_active Application Discontinuation
- 1997-08-18 AT AT97938377T patent/ATE309215T1/de not_active IP Right Cessation
- 1997-08-18 NZ NZ334343A patent/NZ334343A/xx unknown
- 1997-08-18 AU AU40718/97A patent/AU732997B2/en not_active Ceased
- 1997-08-18 IL IL12918797A patent/IL129187A0/xx not_active IP Right Cessation
- 1997-08-18 BR BR9712144-4A patent/BR9712144A/pt not_active IP Right Cessation
- 1997-08-18 CN CNB97198400XA patent/CN1139572C/zh not_active Expired - Fee Related
- 1997-08-18 DE DE69734594T patent/DE69734594T2/de not_active Expired - Fee Related
- 1997-08-18 JP JP10516523A patent/JP2001501221A/ja not_active Ceased
- 1997-08-18 CA CA002266556A patent/CA2266556C/en not_active Expired - Fee Related
- 1997-08-18 HU HU0000882A patent/HUP0000882A3/hu unknown
- 1997-09-24 TW TW086113932A patent/TW492958B/zh not_active IP Right Cessation
- 1997-09-25 ZA ZA9708602A patent/ZA978602B/xx unknown
- 1997-09-29 AR ARP970104462A patent/AR009374A1/es unknown
-
1999
- 1999-03-29 NO NO19991533A patent/NO314080B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998014427A1 (en) | 1998-04-09 |
| JP2001501221A (ja) | 2001-01-30 |
| CN1232452A (zh) | 1999-10-20 |
| HUP0000882A2 (hu) | 2000-09-28 |
| DK0929521T3 (da) | 2006-03-27 |
| AU4071897A (en) | 1998-04-24 |
| IL129187A0 (en) | 2000-02-17 |
| CA2266556C (en) | 2007-11-06 |
| ATE309215T1 (de) | 2005-11-15 |
| EP0929521A1 (en) | 1999-07-21 |
| NO991533D0 (no) | 1999-03-29 |
| ZA978602B (en) | 1998-03-30 |
| CN1139572C (zh) | 2004-02-25 |
| CA2266556A1 (en) | 1998-04-09 |
| DE69734594D1 (en) | 2005-12-15 |
| NZ334343A (en) | 2001-01-26 |
| EP0929521B1 (en) | 2005-11-09 |
| NO991533L (no) | 1999-05-28 |
| AU732997B2 (en) | 2001-05-03 |
| DE69734594T2 (de) | 2006-07-06 |
| KR20000048715A (ko) | 2000-07-25 |
| AR009374A1 (es) | 2000-04-12 |
| TW492958B (en) | 2002-07-01 |
| HUP0000882A3 (en) | 2001-04-28 |
| BR9712144A (pt) | 1999-08-31 |
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